Cytopathology Enigma Portal Collection

26 August 2020
12 November 2024

2018: Volume 29

Endobronchial ultrasound guided transbronchial needle aspirate from subcarinal lymph node: Mesothelial lesion, a diagnostic dilemma

Endoscopic ultrasound guided needle aspirates in the mediastinum can occasionally produce diagnostic difficulties. We describe a mesothelial lesion which presented in this way and outline the process used to make the final diagnosis.

Neoplasms with cytoplasmic vacuoles – Many differential diagnoses on cytology

The origin of metastatic tumours with cytoplasmic vacuoles can be difficult to determine. Not all primary tumours are adenocarcinomas. A rare sub type of a non-epithelial tumour is described and confirmed with the help of immunohistochemical markers.

Aspiration cytology of a scalp lump

Unusual lesions presenting as lumps on the skin can be diagnosed with some confidence by cytology. We describe the cytological features of an uncommon tumor on the scalp.

Cytological diagnosis of a testicular tumour in an infertile male which mimicked epididymitis

This case highlights an important differential diagnosis for testicular swellings associated with infertility and showed typical cytoplasmic inclusions which are characteristic although not always present even on histopathology.

Aspirate from an abdominal lump in a known case of breast carcinoma

In this report we describe the means of diagnosing an incidental abdominal wall lump in an otherwise asymptomatic patient who had a history of previously treated breast carcinoma. FNAC and excision showed the lesion to be a granular cell tumor. Granular cell tumors are quite rare in subcutaneous tissue. FNAC is easily available, widely acceptable and minimally invasive and it can readily be used to screen and characterize such lesions.

Morphology quiz: Pericardial effusion as first manifestation of malignancy

We report a case of pericardial effusion in a 56-year-old female as the initial presentation of multiple myeloma. Serous-haemorrhagic fluid was obtained through a pericardiocentesis. A Papanicolaou stained smear, immunocytochemistry and a bone marrow biopsy illustrate this case.

Non-small cell lung carcinoma metastatic cells in a pericardial effusion

Lung carcinoma can rarely present initially with a pericardial effusion. We describe a case with clearly illustrated images to emphasise that this situation can be encountered in everyday cytology practice.

2017: Volume 29

Enigma portal case: Pleural effusion

The current case is a well-documented rare case of a 14-year-old female with metastatic PTES to the pleural fluid, detailing its cytological and immunophenotypical features. Knowledge of possible morphological aspects of involvement of such singular cases are essential to include these entities as possible differentials along the patients’ diagnostic workup.

Morphology quiz: Renal disease and cytopathology

The authors provide a self-assessment style quiz on various types of urinary cast and their clinical relevance.

2017: Volume 28

Morphology quiz: Mediastinal adenopathy cytology from endobronchial ultrasound transbronchial aspiration (EBUS-TBNA)

Quiz related to cytological examination of infiltrated mediastinal lymph nodes after Endobronchial Ultrasound Transbronchial Aspiration.

Morphology Quiz: Cytopathology of a thyroid neoplasm

Primary Biphasic Synovial Sarcoma of the thyroid gland is exceedingly rare and cytological diagnosis can be very challenging and insidious. A cytological diagnosis of Biphasic Synovial Sarcoma can be hypothesized by an experienced cytopathologist, within a well-coordinate multidisciplinary team work.

Fine needle aspiration cytology from a postauricular swelling

Aspiration from recurrent post auricular swelling is always diagnostic challenge. Presence of polykaryocyte and eosinophil along with serological finding helps in appropriate diagnosis.

2016: Volume 28

Pulmonary actinomycosis: a rare case diagnosed on bronchoalveolar lavage cytology

In this paper we have described a very rare case of actinomycosis in bronchoalveolar lavage.

Detection of cryptococcosis in liquid-based sputum cytology

Sputum cytology is a simple non-invasive technique which can lead to rapid diagnosis of many pulmonary lesions. Liquid-based cytology (LBC) can further aid in the diagnosis by providing a cleaner background. There are only a few reports of detection of cryptococcus in sputum samples. We report a case of cryptococcosis diagnosed on sputum cytology aided with LBC.

Morphology quiz: a 12-year-old child with a tumour in the neck

A 12-year-old male patient came to our clinic with a growing neck mass on the right side. A painless mass was observed in the right neck area below the chin in the physical examination. A single, hypoechoic, solid lesion of approximately 3 cm in size, adjacent to the mandibular area, was detected using ultrasonography. An ultrasound-guided fine-needle aspiration biopsy was performed.