Sciatica is a severe pain that radiates from the back to the hip and outer side of the leg caused by compression of the sciatic nerve. However, traditional treatments can be invasive and costly and may not provide long-term relief. Occupational therapy offers a promising alternative. This article explores occupational therapy-based assessments, interventions, outcomes, progress tracking, pharmacotherapy, challenges owing to surgical approaches, and devices for sciatic pain rehabilitation. Future research could focus on developing and validating new assessment tools and outcome measures specific to sciatica, enabling more accurate evaluation and progress monitoring.

This perspective paper discusses how the development of flexible neural interfaces and devices can overcome the limitations of traditional neurotechnology and could revolutionize investigations into neural principles behind intelligence, consciousness, and behavior. Innovations in material science and device/system-level integrations further extend research capabilities to free-behaving animals, enabling profound insights into neurocognitive functions. Advances in artificial intelligence and brain organoids promise future decoding of complex neural signals. The development of transient materials and devices will provide the foundation for deploying next-generation neurotechnologies in clinics, aiming to treat complex neurogenic diseases and improve neurorehabilitation.

The optimal treatment for chronic intracranial arterial occlusion remains uncertain, with endovascular recanalization presenting significant challenges. Accurate assessment of the distal vascular bed during the procedure is critical for success. This paper introduces a technique utilizing dynamic real-time three-dimensional roadmap guidance, which reduces radiation exposure, contrast medium usage, and procedure-related complications such as vessel perforation or dissection. The dynamic 3D roadmap offers a safe, accurate, and effective tool for endovascular recanalization in chronic intracranial arterial occlusion.

This review highlights the glymphatic system's role in clearing CNS metabolic waste, involving key structures such as AQP4 channels and meningeal lymphatic vessels. It examines how sleep, arterial pulsation, aging, and drugs affect glymphatic function. It also connects glymphatic dysfunction with neurological diseases such as stroke and hydrocephalus and neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease. Moreover, it discusses diagnostic biomarkers, such as enlarged perivascular spaces (PVS) and DTI-ALPS, and emerging treatments, including exercise, 40 Hz multisensory stimulation, lymphaticovenular anastomosis, and targeted drug delivery. These insights offer new avenues for diagnosing and treating CNS diseases.

This paper reviews the pathogenesis of hydrocephalus, emphasizing the role of oxidative stress in hydrocephalus, including the causes of oxidative stress, related signaling pathways, and pathological changes from oxidative stress. This paper aims to discuss the possibility of oxidative stress as a new target for hydrocephalus treatment; thus it details antioxidants with potential for future hydrocephalus research.