Highlights

• Red blood cell (RBC) lifespan variation, is the main cause of variation in glycosylated hemoglobin (HbA1c), independent of blood glucose levels.
• This study highlighted the important impact of RBC lifespan on HbA1c test value in T2DM with HbA1c test value <7%.
• We discovered that the HbA1c test value in type 2 diabetes (T2DM) patients with RBC lifespan <90 days significantly underestimated their general blood glucose condition.
• Our results will provide more useful information to advance management of blood glucose levels for T2DM.

Highlights

• Cardiovascular risk factors worsened during COVID-19 in young people with type 1 diabetes.
• Blood pressure and atherogenic lipid levels were higher in 2020/2021 than expected.
• No further boost in 2020 and 2021 of the preexisting increase in body mass index-SD score.
• A reduction in organized sports but no change in smoking behavior was observed.

Highlights

• This study constructed the first 5-year all-cause mortality risk prediction model for patients with type 2 diabetes mellitus in south China.
• This well-performing model, using highly accessible predictors collected in routine clinical settings, provides a powerful tool for clinicians to identify high-risk diabetic patients.

Highlights

• Reproductive variables are associated with metabolic syndrome (MetS) and its components, but the results are conflicting.
• In this cross-sectional study involving 4453 women over 40, we found that reproductive variables, including menarche, pregnancy, childbirth, breastfeeding, and menopause, may play a role in modulating the risk of MetS.
• Simple information on reproductive history could help identify women who might have a higher risk of metabolic disorder in their later life and prevent the subsequent related chronic diseases.

Highlights

• Mobile health (mHealth) is an emerging forefront in patient-centric care.
• Efficacy of mHealth interventions on health outcomes among older adults with type 2 diabetes is limited.
• Modest benefits on cardiometabolic outcomes with mHealth interventions have uncovered critical gaps in the field and offered insights to address barriers at hand.

Highlights

• Sodium/glucose cotransporter-2 inhibitors (SGLT-2i) showed an important renoprotective effect on sustained administration, regardless of the presence of diabetes, the baseline estimated glomerular filtration rate (eGFR) and different types of SGLT-2i.
• There was an acute decline of eGFR in the initial administration (4.02 ml/min/1.73 m²), and renoprotective effect of SGLT-2i appeared subsequently, which should be noticed by clinicians.

Highlights

• Our study suggests that people with diabetes (PWD) face issues of affording and obtaining insulin and diabetes supplies, even in a population predominantly on private health insurance.
• Financially independent young adults reported increased compensatory strategies and resulting perilous behaviors to ration or obtain insulin and supplies, indicating that additional issues may arise once transitioning into adulthood.
• This study suggests that improved access and affordability of insulin and diabetes supplies is needed to reduce the financial burden and prevent adverse outcomes among PWD.