Highlights

• Sleep management plays a role as a potential target to prevent dementia, and sleep problems are common in patients with type 2 diabetes.
• Type 2 diabetes patients with sleep disorders were found to have more incidence of all cause dementia, Alzheimer disease, and other dementia.
• In patients with type 2 diabetes, men and older adults with sleep disorders were associated with an increased risk of dementia compared to their counterparts without sleep disorders.

Highlights

• To our best knowledge, this is the first study evaluating the association of bone turnover markers with the severity of diabetic retinopathy.
• Lower serum levels of procollagen type 1 N-terminal propeptide and β-cross-linked C-telopeptide of type I collagen (β-CTX) were associated with higher odds for DR, while β-CTX was associated with its severity.

Highlights

• Distinct trajectories of estimated glomerular filtration rate (eGFR) were associated with myocardial infarction (MI) risk in a diabetic or prediabetic population.
• The MI risk was higher in the high-decreasing group although the eGFR levels were similar to the moderate-stable group during the last exposure period.
• The moderate-increasing group still had a significantly increased MI risk when reaching the normal range.

Highlights

• The survival rate and the limb salvage rate of patients in this study were 76.8% and 97.6%.
• This study suggested that fibrinogen may be used as an index to predict restenosis after interventional intervention.
• The results indicated that the detection of sdLDL may provide a new research direction for preventing restenosis after intervention.

Highlights

• A machine learning model can significantly predict imminent development of islet autoimmunity based on environmental, genetic, and metabolic features.
• The machine learning algorithm feature selection identified type 1 diabetes-associated single nucleotide polymorphisms from The Environmental Determinants of the Diabetes in the Young (TEDDY) analysis are correlated to related data from the Diabetes Autoimmunity Study in the Young (DAISY) study.
• Most of the metabolic features predicting the development of islet autoantibodies belonged to three pathways; lipid oxidation, phospholipase A2 signaling, and pentose phosphate.

Highlights

• MODY is mostly overlooked due to uncertain clinical presentations and is often misdiagnosed as T1DM.
• This paper presents possible clinical and laboratory clues to consider a diagnosis of MODY in children presenting with hyperglycaemia.
• In addition, this paper reviews the association of these probable markers with MODY-causing genes.

Highlights

• Inhaled insulin added to basal insulin achieved comparable efficacy to insulin lispro in type 1 diabetes mellitus.
• Inhaled insulin has a more rapid postprandial glycemic response than the insulin analogue insulin lispro.