Due to the concept of oligometastasis in lung cancer, thermal ablation combined with other therapies is gradually recognized.This article reviews the concept, classification, local treatment and prognosis of extracranial oligometastasis.

Significant predictors for doxorubicin pharmacokinetic variability.

Representative evidence relevant to RT combined with ICI in the brain, lung, head and neck and pelvic malignance suggest that RT+ICI combination therapy might augment toxicities without augmenting sAE. Early recognition and proper management is essential to prevent sAE and indicate a good prognosis.

We report a large multicenter study of 980 locally advanced nasopharyngeal carcinoma patients treated with either cisplatin or carboplatin concurrently with radiotherapy. The results represent real-world evidence with extensive details of patient characteristics, treatment modalities, tolerability, and survival outcomes. Carboplatin should be considered as an alternative regimen, particularly in cisplatin-ineligible patients.

Frailty is a common clinical syndrome among the elderly; however, it is frequently neglected in patients with hematological malignancies, especially among the Asian population. This is the first study to evaluate the prevalence rate and effect of frailty on survival outcome in elderly patients undergoing immunochemotherapy for the treatment of B-cell lymphoma in Taiwan. This study found a negative association between the numbers of geriatric dimensional impairment and survival outcome. Pretreatment frailty assessment is essential to assist clinicians and patients with B-cell lymphoma with prognosis prediction and counseling on an appropriate treatment goal.

We conducted a A multi-institutional retrospective study of intravesical recurrence (IVR) after nephroureterectomy. Contrary to our expectations, IVR risk factors were ≦pT1, pN0/pNx, G1/2, and absence of LVI. These findings provide insight into IVR, which may help with the development of personalized prevention and treatment strategies.

In this study we demonstrate the utility of multiparametric MRI in prediction of response to radiotherapy in cases of locally advanced carcinoma cervix. Pre-treatment apparent diffusion coefficient of the tumor was the most accurate measure for predicting response to treatment as well as for treatment induced fractional volume reduction.

Posterior approach only total en bloc spondylectomy is safe to performed without pre-operative embolization in spinal metastasis patients. Longer term follow-up studies will be able to further identify the benefits of TES for the long-term local control of diseases

Graphical Abstract: Decrease in systemic immune-inflammation index (SII) is associated with better histological tumor response and longer overall survival.

Among around 400 Korean breast cancer survivors, we found that a high BMI was associated with unfavorable levels of inflammatory markers. High BMI at study entry, more so than at diagnosis, showed a strong association with the summary z-score for inflammatory markers.

Many health professionals caring for patients with cancer often discuss the financial concerns of their patients and have increasing awareness of these issues but are limited by time and practical supports. Resources supporting financial-related discussions for all health professionals are urgently needed to advance action in this field.

We retrospectively analyzed malignant lymphoma in patients who underwent auto-peripheral blood stem cell transplantation, with high-dose cytarabine MEAM therapy as the conditioning regimen. In all cases, the 3-year overall survival after transplantation was 80.6% and the 3-year progression-free survival after transplantation was 65.7%. There were no cases of treatment-related mortality with this therapy, and this one tended to be more effective than ICE and BU/CY/VP-16 therapies.

Radiation therapy (RT) is effective treatment for symptomatic multiple myeloma-related bone disease. This population-based study showed increasing use of short course RT of 2-5 fractions. However, the use of single-fraction RT remains low, even at the end of life. There is large institutional variation in practice.

We evaluated the experience of patients from an Asian population who underwent awake craniotomy for brain tumor resection. We showed that there is high level of acceptance for awake craniotomy in this population. Patients generally felt well-prepared before the surgery, tolerated intraoperative procedure and motor/language testing well, and were mostly satisfied with the postoperative care. The overall experience was overwhelmingly positive—100% “good” or “excellent” rating.

Graphical Abstract: Our study showed overall survival comparable to that reported by pivotal clinical trials and other recent RWD studies. Other survival outcomes were also reassuring and overall, the findings support the achievement of health gains from use of ICI in advanced unresectable and metastatic melanoma in New Zealand.

Diagnostic efficacy in therapeutic response by different imaging measurement of hypopharyngeal carcinoma with evaluated and proved diagnostic performance in different time point. The thickness and axial area distinguish prognosis better than RECIST 1.1. The thickness is the best for therapeutic response evaluation.

Although the incidence of thyroid cancer in Chinese population was lower than the global average, given the huge population base, the burden of thyroid cancer disease in China cannot be ignored, especially the fatal burden among males in China.

Graphical Abstract: Colorectal cancer local staging using preoperative imaging may differ between the multidisciplinary team (MDT) opinion and original radiology report. This is the first prospective study to compare diagnostic agreement between a specialised colorectal cancer MDT and the radiology report in this setting, demonstrating consistent local staging between the two modalities.

This study aimed to describe the current practice in Australasia in managing potentially resectable pancreatic cancer. Description of neoadjuvant chemotherapy (NAT), surgical and survival outcomes in borderline resectable pancreatic cancer (BRPC) using real-world data was extracted from PURPLE (Pancreatic cancer: Understanding Routine Practice and Lifting End results).

Image-guided percutaneous pericardial effusion drainage for cancer patients is safe and contributes to the alleviation of symptoms. Additionally, catheter removal is possible in most patients, thereby allowing a catheter-free period for them.

Cancer stakeholders’ perspectives of COVID-19 vaccination.

• One in five participants with CIPN reported their symptoms interfered with their ability to exercise.

• Participants aged ≥60, with grade ≥1 CIPN or BMI ≥30, were less likely to meet physical activity guidelines.

• Tailored interventions are needed to increase physical activity post treatment to improve physical function and quality of life.

Color fluorescence imaging using indocyanine green would allow for the accurate and safe harvest of sentinel lymph nodes by the improvement of visibility in head and neck cancer. However, it would be currently preferable that this method is used complementally in combination with the conventional methods due to low sensitivity.

Image-guided percutaneous pericardial effusion drainage for cancer patients is safe and contributes to the alleviation of symptoms. Additionally, catheter removal is possible in most patients, thereby allowing a catheter-free period for them.