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    2023
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Research Article
Open Access

A Novel Pyroptosis-Based Prognostic Model Correlated with the Parainflammatory Immune Microenvironment of Pancreatic Cancer

Kong-kong Wei,  Zhi-xing Du,  Jun-ge Deng,  Jin-wei Yang,  Hao Chen, 
  • First Published: 21 December 2023
Research Article
Open Access

DJ-1: A Potential Biomarker Related to Prognosis, Chemoresistance, and Expression of Microenvironmental Chemokine in HR-Positive Breast Cancer

Yinghong Xie,  Yuancheng Li,  Mengzhu Yang, 
  • First Published: 13 December 2023
Research Article
Open Access

The Expression of Semaphorin3E in Vagal Ganglion and Lung Tissue Is Related to Airway Hyperresponsiveness in Murine Asthma Model

Liyan Chen,  Xiaohui Yuan,  Yaowei He,  Zichuan Fan,  Ya Guan,  Qiuying Li,  Yaying Chen,  Lianglan Bao,  Yidan Huang,  Kefang Lai, 
  • First Published: 11 December 2023
Research Article
Open Access

Development of an Anoikis-Related Gene Signature for Lung Squamous Cell Carcinomato Predict Prognosis, Immune Landscape, and Immunotherapy Response

Jian Liu,  Hui Zheng,  Li Wei, 
  • First Published: 09 December 2023
Research Article
Open Access

Suppression of NK Cell Activation by JAK3 Inhibition: Implication in the Treatment of Autoimmune Diseases

Wai Chung Wu,  Carol Shiu,  Tak Keung Tong,  Shui On Leung,  Chin Wai Hui, 
  • First Published: 08 December 2023
Research Article
Open Access

Risk Prediction Models for Invasive Mechanical Ventilation in Patients with Autoimmune Encephalitis: A Retrospective Cohort Study

Shiyang Xie,  Meilin Chen,  Luying Qiu,  Long Li,  Shumin Deng,  Fang Liu,  Hefei Fu,  Yanzhe Wang, 
  • First Published: 05 December 2023
Research Article
Open Access

Identification and Development of Synovial B-Cell-Related Genes Diagnostic Signature for Rheumatoid Arthritis

Jifeng Tang,  Jinfang Xia,  Huiming Sheng,  Jinpiao Lin, 
  • First Published: 25 November 2023
Research Article
Open Access

EGF-Receptor against Amphiregulin (AREG) Influences Costimulatory Molecules on Monocytes and T Cells and Modulates T-Cell Responses

Stephan Dreschers,  Christopher Platen,  Louise Oppermann,  Caitlin Doughty,  Andreas Ludwig,  Aaron Babendreyer,  Thorsten W. Orlikowsky, 
  • First Published: 24 November 2023
Review Article
Open Access

Targeting Neutrophil Extracellular Traps: A Novel Antitumor Strategy

Hao Zuo,  Mengjie Yang,  Qian Ji,  Shengqiao Fu,  Xi Pu,  Xu Zhang,  Xu Wang, 
  • First Published: 09 November 2023
Research Article
Open Access

Sestrin2 Regulates Endoplasmic Reticulum Stress-Dependent Ferroptosis to Engage Pulmonary Fibrosis by Nuclear Factor Erythroid 2-Related Factor 2/Activating Transcription Factor 4 (NRF2/ATF4)

Zhaoxing Dong,  Ting Li,  Cenli Wang,  Yong Zhou,  Zhongkai Tong,  Xuekui Du, 
  • First Published: 07 November 2023
Research Article
Open Access

Common Pollen Modulate Immune Responses against Viral-Like Challenges in Airway Coculture Model

Tarleena Tossavainen,  Maria-Viola Martikainen,  Hanna Loukola,  Marjut Roponen, 
  • First Published: 06 November 2023
Research Article
Open Access

GPC3 Promotes Lung Squamous Cell Carcinoma Progression and HLA-A2-Restricted GPC3 Antigenic Peptide-Modified Dendritic Cell-Induced Cytotoxic T Lymphocytes to Kill Lung Squamous Cell Carcinoma Cells

Jing Ning,  Jianqiao Ding,  Shu Wang,  Youhong Jiang,  Daqing Wang,  Shenyi Jiang, 
  • First Published: 06 November 2023
Review Article
Open Access

Understanding How Minerals Contribute to Optimal Immune Function

Alina Stefanache,  Ionut-Iulian Lungu,  Ioan-Adrian Butnariu,  Gabriela Calin,  Cristian Gutu,  Constantin Marcu,  Carmen Grierosu,  Elena Roxana Bogdan Goroftei,  Letitia-Doina Duceac,  Marius Gabriel Dabija,  Florina Popa,  Daniela Damir, 
  • First Published: 01 November 2023
Research Article
Open Access

Bone Mesenchymal Stem Cell-Derived Small Extracellular Vesicles Ameliorated Lipopolysaccharide-Induced Lung Injury Via the miR-21-5p/PCSK6 Pathway

Bo Cai,  Weidong Song,  Song Chen,  Jie Sun,  Rui Zhou,  Zhen Han,  Jian Wan, 
  • First Published: 28 October 2023
Research Article
Open Access

Circulating miR-320b Contributes to CD4+ T-Cell Proliferation in Systemic Lupus Erythematosus via MAP3K1

Zutong Li,  Rou Wang,  Dandan Wang,  Shujie Zhang,  Hua Song,  Shuai Ding,  Yantong Zhu,  Xin Wen,  Hui Li,  Hongwei Chen,  Shanshan Liu,  Lingyun Sun, 
  • First Published: 26 October 2023
Research Article
Open Access

Tim-3 Is Differentially Expressed during Cell Activation and Interacts with the LSP-1 Protein in Human Macrophages

Ranferi Ocaña-Guzman,  Lucero A. Ramon-Luing,  Luis A. Vazquez-Bolaños,  Michelle Rodríguez-Alvarado,  Fausi Bulhusen-Rodriguez,  Alonso Torres-Hatem,  Karen Gonzalez-Torres,  Mariana Citlalli de Alba-Alvarado,  Isabel Sada-Ovalle, 
  • First Published: 26 October 2023
Research Article
Open Access

The Value of IgM Memory B-Cells in the Assessment of Splenic Function in Childhood Cancer Survivors at Risk for Splenic Dysfunction: A DCCSS-LATER Study

Bente M. Houtman,  Iris Walraven,  Elke de Grouw,  Richard W. M. van der Maazen,  Leontien C. M. Kremer,  Eline van Dulmen-den Broeder,  Marry M. van den Heuvel-Eibrink,  Wim J. E. Tissing,  Dorine Bresters,  Helena J. H. van der Pal,  Andrica C. H. de Vries,  Marloes Louwerens,  Margriet van der Heiden-van der Loo,  Sebastian J. C. Neggers,  Geert O. Janssens,  Nicole M. A. Blijlevens,  Annechien J. A. Lambeck,  Frank Preijers,  Jacqueline J. Loonen, 
  • First Published: 20 October 2023
Research Article
Open Access

Dupilumab Efficacy in Patients with Type 2 Asthma with and without Elevated Blood Neutrophils

Eugene R. Bleecker,  Reynold A. Panettieri Jr.,  Njira L. Lugogo,  Jonathan Corren,  Nadia Daizadeh,  Juby A. Jacob-Nara,  Yamo Deniz,  Paul J. Rowe,  Angela Khodzhayev,  Xavier Soler,  Thomas J. Ferro,  Christopher N. Hansen, 
  • First Published: 19 October 2023
Research Article
Open Access

Association between Butter, Margarine, and Olive Oil Intake and Asthma Symptoms among School Children: Result from a Large-Scale Cross-Sectional Study

Arezoo Sadat Emrani,  Bahareh Sasanfar,  Zahra Nafei,  Nasrin Behniafard,  Amin Salehi-Abargouei, 
  • First Published: 18 October 2023
Research Article
Open Access

Irradiation Attenuates Systemic Lupus Erythematosus-Like Morbidity in NZBWF1 Mice: Focusing on CD180-Negative Cells

Kazuko Fujita,  Taku Kuwabara,  Bing Wang,  Kaoru Tanaka,  Kei Ito,  Yuri Akishima-Fukasawa,  Tetuo Mikami,  Yoshikiyo Akasaka,  Toshiharu Ishii, 
  • First Published: 18 October 2023
Research Article
Open Access

Sex-Specific Immune Responses to Seasonal Influenza Vaccination in Diabetic Individuals: Implications for Vaccine Efficacy

Anirban Sengupta,  Noha Al-Otaibi,  Jorma Hinkula, 
  • First Published: 17 October 2023
Research Article
Open Access

Broadly Reactive SARS-CoV-2-Specific T-Cell Response and Participation of Memory B and T Cells in Patients with Omicron COVID-19 Infection

Pragya D. Yadav,  Rima R. Sahay,  Sukeshani Salwe,  Diptee Trimbake,  Prasad Babar,  Gajanan N. Sapkal,  Gururaj R. Deshpande,  Kiran Bhise,  Anita M. Shete,  Priya Abraham,  Anuradha S. Tripathy, 
  • First Published: 17 October 2023
Review Article
Open Access

A Review of Antibiotic Efficacy in COVID-19 Control

Hamidreza Hekmat,  Aziz Rasooli,  Zeinab Siami,  Kauthar Amir Rutajengwa,  Zahra Vahabi,  Fatemeh Alsadat Mirzadeh, 
  • First Published: 10 October 2023
Research Article
Open Access

Differential Production of Midkine and Pleiotrophin by Innate APCs upon Stimulation through Nucleic Acid-Sensing TLRs

Elias A. Said,  Sumaya Al-Dughaishi,  Wadha Al-Hatmi,  Iman Al-Reesi,  Mohammed S. Al-Balushi,  Atika Al-Bimani,  Juma Z. Al-Busaidi,  Marwa Al-Riyami,  Murtadha Al-Khabori,  Salam Al-Kindi,  Francesco A. Procopio,  Shadia Al-Sinawi,  Aliyaa Al-Ansari,  Crystal Y. Koh,  Khalid Al-Naamani,  Ali A. Al-Jabri, 
  • First Published: 09 October 2023
Research Article
Open Access

The Role of the IL-33/ST2 Axis in CpG-Induced Macrophage Activation Syndrome

Yuanji Dong,  Rongfen Gao,  Kailin He,  Jixin Zhong,  Lingli Dong, 
  • First Published: 05 October 2023
Research Article
Open Access

Diagnostic Value of CD25, CD69, and CD134 on Tuberculosis-Specific Antigen-Stimulated CD4+ T Cells for Tuberculous Pleurisy

Hanlu Shi,  Liping Yang,  Fujie Zhang,  Yu Zhou,  Yonglie Zhou, 
  • First Published: 27 September 2023
Research Article
Open Access

Alterations in the “Gut–Liver Axis” on Rats with Immunological Hepatic Fibrosis

Zhaoyao Qi,  Xinxin Qi,  Yuanhui Xu,  Hongguang Sun,  Dengfeng Li,  Jincun Liu,  Meili Cong,  Tao Liu, 
  • First Published: 21 September 2023
Research Article
Open Access

sNASP Mutation Aggravates to the TLR4-Mediated Inflammation in SLE by TAK1 Pathway

Yatao Bao,  Meng Lian,  Yong Chen,  Xiaotian Gu,  Kunyu Cao,  Xiaoping Du,  Jiyu Ju, 
  • First Published: 20 September 2023
Research Article
Open Access

Super Enhancer Regulatory Gene FYB1 Promotes the Progression of T Cell Acute Lymphoblastic Leukemia by Activating IGLL1

Kunlong Zhang,  Jun Lu,  Fang Fang,  Yongping Zhang,  Juanjuan Yu,  Yanfang Tao,  Wenyuan liu,  Lihui Lu,  Zimu Zhang,  Xinran Chu,  Jianwei Wang,  Xiaolu Li,  Yuanyuan Tian,  Zhiheng Li,  Qian Li,  Xu Sang,  Li Ma,  Ningling Wang,  Jian Pan,  Shaoyan Hu, 
  • First Published: 19 September 2023
Research Article
Open Access

Dupilumab’s Impact on Blood Parameters in Nasal Polyposis: 18-Month Follow-Up in Real Life

Antonella Loperfido,  Andrea Ciofalo,  Carlo Cavaliere,  Elona Begvarfaj,  Francesca Cascone,  Giacomo Alfonzo,  Rosalba Cadeddu,  Stefano Millarelli,  Gianluca Bellocchi,  Antonio Greco,  Marco de Vincentiis,  Simonetta Masieri, 
  • First Published: 15 September 2023
Research Article
Open Access

Evaluation of CD47 in the Suppressive Tumor Microenvironment and Immunotherapy in Prostate Cancer

Qianqian Wang,  Chunxaing Feng,  Yuchun Chen,  Tianming Peng,  Yong Li,  Kunlin Wu,  Xiaoyong Pu,  Hanzhong Chen,  Jiumin Liu, 
  • First Published: 09 September 2023
Review Article
Open Access

Endoplasmic Reticulum Stress in Systemic Lupus Erythematosus and Lupus Nephritis: Potential Therapeutic Target

Hui-Yuan Li,  Li-Feng Huang,  Xiao-Rong Huang,  Dan Wu,  Xiao-Cui Chen,  Ji-Xin Tang,  Ning An,  Hua-Feng Liu,  Chen Yang, 
  • First Published: 31 August 2023
Research Article
Open Access

Effect of Differently Polarized Human Macrophages on the SH-SY5Y Cells Damaged by Ischemia and Hypoxia In Vitro

Ivan Mikhailovich Rashchupkin,  Ekaterina Yakovlevna Shevela,  Aleksandra Aleksandrovna Maksimova,  Marina Aleksandrovna Tikhonova,  Aleksandr Anatolevich Ostanin,  Elena Removna Chernykh, 
  • First Published: 31 August 2023
Research Article
Open Access

Physiological Changes in the Levels of Anti-Cytokine Autoantibodies in Early Pregnancy Are Missing in Pregnant Women with Hashimoto’s Thyroiditis

Szabina Erdő-Bonyár,  Diána Simon,  Anna Bajnok,  Jasper Nörenberg,  Tímea Serény-Litvai,  Ákos Várnagy,  Kálmán Kovács,  Eszter Hantosi,  Emese Mezősi,  Tímea Berki, 
  • First Published: 25 August 2023
Research Article
Open Access

Sesamin Protects against APAP-Induced Acute Liver Injury by Inhibiting Oxidative Stress and Inflammatory Response via Deactivation of HMGB1/TLR4/NFκB Signal in Mice

Hui Du,  Shiwen Tong,  Ge Kuang,  Xia Gong,  Ningman Jiang,  Xian Yang,  Hao Liu,  Nana Li,  Yao Xie,  Yang Xiang,  Jiashi Guo,  Zhenhan Li,  Yinglin Yuan,  Shengwang Wu,  Jingyuan Wan, 
  • First Published: 24 August 2023
Review Article
Open Access

The Important Role of Interleukin-2 in COVID-19

Leila Ghanbari Naeini,  Laleh Abbasi,  Farzaneh Karimi,  Pajman Kokabian,  Fahimeh Abdi Abyaneh,  Delaram Naderi, 
  • First Published: 22 August 2023
Research Article
Open Access

Periventricular Microglia Polarization and Morphological Changes Accompany NLRP3 Inflammasome-Mediated Neuroinflammation after Hypoxic–Ischemic White Matter Damage in Premature Rats

Liu Yang,  Yajun Zhang,  Xuefei Yu,  Danni Li,  Na Liu,  Xindong Xue,  Jianhua Fu, 
  • First Published: 19 August 2023
Retraction
Open Access

Retracted: Ameliorative Impact of Liraglutide on Chronic Intermittent Hypoxia-Induced Atrial Remodeling

Journal of Immunology Research, 
  • First Published: 16 August 2023

Retraction
Open Access

Retracted: Mutational Screening of Skeletal Genes in 14 Chinese Children with Osteogenesis Imperfecta Using Targeted Sequencing

Journal of Immunology Research, 
  • First Published: 16 August 2023

Retraction
Open Access

Retracted: Comparison of Outcomes between Two Surgical Techniques for Patients with Intestinal Neuronal Dysplasia

Journal of Immunology Research, 
  • First Published: 16 August 2023

Retraction
Open Access

Retracted: Relationship between Platelet-to-Lymphocyte Ratio and Lymphocyte-to-Monocyte Ratio with Spontaneous Preterm Birth: A Systematic Review and Meta-analysis

Journal of Immunology Research, 
  • First Published: 16 August 2023

Research Article
Open Access

The Immunomodulatory Activity of Punica granatum L. Peel Extract Increases the Lifespan of Mice with Lethal Sepsis

Liana de O. Trovão,  Liliane dos S. Rodrigues,  Priscila M. Mendes,  Patrícia C. S. Alves,  Aluísio da S. Oliveira,  Jefferson M. Brito,  André A. M. Vale,  Dimitrius V. de O. Garbis,  Gisele Simão,  Ana Paula S. A. dos Santos,  Paulo V. S. Pereira,  Lucilene A. Silva,  Andresa A. Berretta,  Flávia R. F. Nascimento,  Rosane N. M. Guerra,  Valério Monteiro-Neto,  Elizabeth S. Fernandes,  Márcia C. G. Maciel, 
  • First Published: 16 August 2023
Review Article
Open Access

IL-17: Balancing Protective Immunity and Pathogenesis

Lu Sun,  Lufei Wang,  Bethany B. Moore,  Shaoping Zhang,  Peng Xiao,  Ann M. Decker,  Hom-Lay Wang, 
  • First Published: 12 August 2023
Research Article
Open Access

Analyzation of the Peripheral Blood Mononuclear Cells Atlas and Cell Communication of Rheumatoid Arthritis Patients Based on Single-Cell RNA-Seq

Xinqiang Song,  Yu Zhang,  Lijun Zhao,  Jinke Fan,  Tao Peng,  Ying Ma,  Nailiang Guo,  Xiaotong Wang,  Xudong Liu,  Zhe Liu,  Lei Wang, 
  • First Published: 12 August 2023
Research Article
Open Access

Novel Predictive Scoring System for Intravenous Immunoglobulin Resistance Helps Timely Intervention in Kawasaki Disease: The Chinese Experience

Yan Wang,  Shuoyin Huang,  Panpan Wang,  Yan Wu,  Yingying Liu,  Yuting Pan,  Jinyuan Dong,  Zhidan Fan,  Haiguo Yu, 
  • First Published: 09 August 2023
Review Article
Open Access

Insights Regarding the Role of Inflammasomes in Leukemia: What Do We Know?

Fabíola Silva Alves-Hanna,  Juniel Assis Crespo-Neto,  Glenda Menezes Nogueira,  Daniele Sá Pereira,  Amanda Barros Lima,  Thaís Lohana Pereira Ribeiro,  Vitória Giovanna Rodrigues Santos,  Joey Ramone Ferreira Fonseca,  Fábio Magalhães-Gama,  Aya Sadahiro,  Allyson Guimarães Costa, 
  • First Published: 04 August 2023
Research Article
Open Access

Early Life Exposure to Human Milk Oligosaccharides Reduces Allergic Response in a Murine Asthma Model

Tahereh Bozorgmehr,  Rozlyn C. T. Boutin,  Sarah E. Woodward,  Katherine Donald,  Jo May Chow,  Rachael H. Buck,  B. Brett Finlay, 
  • First Published: 29 July 2023
Research Article
Open Access

S100A9 Regulated M1/M2 Macrophage Polarization in Interleukin-10-Induced Promotion of Malignant Pleural Effusion

Xue-Bin Pei,  Feng-Shuang Yi,  Shu-Feng Dong,  Qing-Yu Chen,  Xin-Yu Shi, 
  • First Published: 25 July 2023
Research Article
Open Access

MicroRNA-22 Regulates the Pro-inflammatory Responses and M1 Polarization of Macrophages by Targeting GLUT1 and 4-1BBL

Young Jun Kang, 
  • First Published: 10 July 2023
Research Article
Open Access

Small Extracellular Vesicles Secreted by iPSC-Derived MSCs Ameliorate Pulmonary Inflammation and Lung Injury Induced by Sepsis through Delivery of miR-125b-5p

Wei Peng,  Yun Yang,  Jiaquan Chen,  Zeyao Xu,  Yuanlei Lou,  Qi Li,  Ning Zhao,  Kejian Qian,  Fen Liu, 
  • First Published: 01 July 2023
Research Article
Open Access

Effect of Saengmaeksan on Fatigue, Liver Function, and Immunity Combined with High-Intensity Training

Shi Juan,  Jae-Hoon Lee,  Se-Jong Won,  SiYeon Oh,  Min-Seong Ha, 
  • First Published: 30 June 2023
Research Article
Open Access

miR-1 Inhibits the Ferroptosis of Chondrocyte by Targeting CX43 and Alleviates Osteoarthritis Progression

Ming Zhou,  Chenjun Zhai,  Kai Shen,  Gang Liu,  Lei Liu,  Jian He,  Jun Chen,  Yaozeng Xu, 
  • First Published: 30 June 2023
Review Article
Open Access

Spotlight on NLRP6 and Tumor Research Situation: A Potential Cancer Participant

Liangzheng Chang,  Yuying Tian,  Lei Xu,  Qiuyao Hao,  Lingyu Song,  Yinying Lu,  Yunhuan Zhen, 
  • First Published: 28 June 2023
Research Article
Open Access

Serum TGF-β1 and CD14 Predicts Response to Anti-TNF-α Therapy in IBD

Stepan Coufal,  Miloslav Kverka,  Jakub Kreisinger,  Tomas Thon,  Filip Rob,  Martin Kolar,  Zuzana Reiss,  Dagmar Schierova,  Klara Kostovcikova,  Radka Roubalova,  Lukas Bajer,  Zuzana Jackova,  Martin Mihula,  Pavel Drastich,  Jana Tresnak Hercogova,  Michaela Novakova,  Martin Vasatko,  Milan Lukas,  Helena Tlaskalova-Hogenova,  Zuzana Jiraskova Zakostelska, 
  • First Published: 20 June 2023
Review Article
Open Access

The Potential Nexus between Helminths and SARS-CoV-2 Infection: A Literature Review

Hayder M. Al-kuraishy,  Ali I. Al-Gareeb,  Luay Alkazmi,  Maisra M. El-Bouseary,  Rabab S. Hamad,  Mahmoud Abdelhamid,  Gaber El-Saber Batiha, 
  • First Published: 20 June 2023
Research Article
Open Access

Evaluation of Der p 10 in a Cohort of European Children: Role of Molecular Diagnostics and Clinical Features

Cristiana Indolfi,  Giulio Dinardo,  Angela Klain,  Alessandra Salvatori,  Marica Esposito,  Viviana Vela,  Fabio Decimo,  Giorgio Ciprandi,  Michele Miraglia del Giudice, 
  • First Published: 19 June 2023
Review Article
Open Access

Role of Extracellular microRNAs in Sepsis-Induced Acute Lung Injury

Chenlu Xiong,  Xuan Huang,  Shibiao Chen,  Yong Li, 
  • First Published: 19 June 2023
Research Article
Open Access

Circadian Regulator-Mediated Molecular Subtypes Depict the Features of Tumor Microenvironment and Indicate Prognosis in Head and Neck Squamous Cell Carcinoma

Ling Aye,  Zhanying Wang,  Fanghua Chen,  Yujun Xiong,  Jiaying Zhou,  Feizhen Wu,  Li Hu,  Dehui Wang, 
  • First Published: 12 June 2023
Research Article
Open Access

Interferon-Induced Transmembrane Protein 3 rs34481144 C/T Genotype and Clinical Parameters Related to Progression of COVID-19

Melika Gholami,  Fatemeh Sakhaee,  Fahimeh Mirzaei Gheinari,  Fattah Sotoodehnejadnematalahi,  Morteza Ghazanfari Jajin,  Mohammad Saber Zamani,  Iraj Ahmadi,  Enayat Anvari,  Abolfazl Fateh, 
  • First Published: 07 June 2023
Research Article
Open Access

KIF22 in the Prognosis and Immune Biomarking of Pan-Cancer

Xiuhong Guo,  Huayue Cao,  Mei Hu,  Yuening Wu,  Jingxiang Li, 
  • First Published: 31 May 2023
Research Article
Open Access

The Underlying Mechanism of Duanteng Yimu Decoction in Inhibiting Synovial Hyperplasia in Rheumatoid Arthritis

Wei Feng,  Xiao-Qin Zhong,  Xue-Xia Zheng,  Qing-Ping Liu,  Min-Ying Liu,  Xiao-Bao Liu,  Chang-Song Lin,  Qiang Xu, 
  • First Published: 21 May 2023
Research Article
Open Access

Production of Dermatophagoides farinae Having Low Bacterial Content Using Ampicillin

Ju Yeong Kim,  Myung-hee Yi,  Myungjun Kim,  Jun Ho Choi,  Seogwon Lee,  Tai-Soon Yong, 
  • First Published: 18 May 2023
Review Article
Open Access

Protein Phosphatase 2A: Role in T Cells and Diseases

Suyasha Roy,  Lalit Batra, 
  • First Published: 17 May 2023
Research Article
Open Access

Predicting the Progress of Tuberculosis by Inflammatory Response-Related Genes Based on Multiple Machine Learning Comprehensive Analysis

Shuai Ma,  Peifei Peng,  Zhihao Duan,  Yifeng Fan,  Xinzhi Li, 
  • First Published: 16 May 2023
Research Article
Open Access

Clinical Characteristics and Serum Cytokines Profiling in Hospitalized COVID-19 Patients in Lebanon

Farouk F. Abou Hassan,  Mirna Bou Hamdan,  Nada M. Melhem, 
  • First Published: 16 May 2023
Research Article
Open Access

Sensitization to nsLTP: A Retrospective Study in An Italian Pediatric Population over the Last Decade

Cristiana Indolfi,  Giulio Dinardo,  Angela Klain,  Marcella Contieri,  Giuseppina Rosaria Umano,  Fabio Decimo,  Salvatore Abbadessa,  Carolina Vitulano,  Giorgio Ciprandi,  Michele Miraglia del Giudice, 
  • First Published: 16 May 2023
Research Article
Open Access

Systemic Immune-Inflammatory Index, Tumor-Infiltrating Lymphocytes, and Clinical Outcomes in Esophageal Squamous Cell Carcinoma Receiving Concurrent Chemoradiotherapy

Jun Yang,  Jifang Zheng,  Jianjian Qiu,  Mengyan Zhang,  Lingyun Liu,  Zhiping Wang,  Qunhao Zheng,  Yanyan Liu,  Mingqiu Chen,  Jiancheng Li, 
  • First Published: 16 May 2023
Research Article
Open Access

Exosome Derived from Human Umbilical Cord Mesenchymal Cell Exerts Immunomodulatory Effects on B Cells from SLE Patients

Ying Zhao,  Wenbin Song,  Zilin Yuan,  Min Li,  Gang Wang,  Liping Wang,  Yueping Liu,  Bo Diao, 
  • First Published: 12 May 2023
Research Article
Open Access

Exogenous Interleukin-37 Alleviates Hepatitis with Reduced Dendritic Cells and Induced Regulatory T Cells in Acute Murine Cytomegalovirus Infection

Yufei Ruan,  Zhengwang Wen,  Ke Chen,  Jianan Xi,  Bo Wu,  Zhiyong Xu,  Minzhi Jiang,  Junling Zhang,  Yiping Chen,  Qi Liu, 
  • First Published: 12 May 2023
Research Article
Open Access

Comprehensive Analysis of m7G-Related Genes and Chronic Hepatitis B: Diagnostic Markers, Immune Microenvironment Regulation, Disease Progression

Rongzheng Zhang,  Yan Xia,  Jianming Dong,  Xiaomei Ju,  Kun Zhou,  Xinyang Cao,  Jiaqi Li,  Jiaqiu Ru,  Mengrui Guo,  Shuyun Zhang, 
  • First Published: 10 May 2023
Research Article
Open Access

Development and Validation of an Immunotherapy-Related Prognostic Signature Based on Lymph Node Ratio for Gastric Cancer

Jianxin Li,  Ting Han,  Xin Wang,  Yinchun Wang,  Xuan Chen,  Wangsheng Chen,  Qingqiang Yang, 
  • First Published: 29 April 2023
Research Article
Open Access

Increased FOXM1 Expression was Associated with the Prognosis and the Recruitment of Neutrophils in Endometrial Cancer

Jing Chen,  Pusheng Yang,  Shaojing Li,  Yichen Feng, 
  • First Published: 29 April 2023
Research Article
Open Access

Antieosinophil Antibodies Alone or in Combination with Antineutrophil Cytoplasmic Antibodies (ANCA) Detected in Different Autoimmune Conditions

Régis Dieckmann,  Rille Pullerits,  Johan Bylund,  Anna Karlsson-Bengtsson,  Hans Herlitz,  Christine Wennerås,  Pontus Thulin, 
  • First Published: 26 April 2023
Research Article
Open Access

Molecular Allergy Diagnostics in Children with Cow’s Milk Allergy: Prediction of Oral Food Challenge Response in Clinical Practice

Maria Angela Tosca,  Irene Schiavetti,  Roberta Olcese,  Chiara Trincianti,  Giorgio Ciprandi, 
  • First Published: 24 April 2023
Research Article
Open Access

Immune Cell Response during COVID-19 Infection and following SARS-CoV-2 Vaccination in Patients Admitted to Intensive Care Unit

Khadija Bahrini,  Nejla Stambouli,  Mouna Ben Azaiez,  Aicha Rebai,  Ferid Abid,  Chihebeddine Romdhani,  Iheb Labben,  Hédi Gharsallah,  Mustapha Ferjani, 
  • First Published: 24 April 2023
Research Article
Open Access

Morroniside Ameliorates Endotoxin-Induced Uveitis by Regulating the M1/M2 Polarization Balance of Macrophages

Wenjie Li,  Lin Liu,  Ziwei Zhang,  Hong Lu, 
  • First Published: 23 April 2023
Review Article
Open Access

Insights into the Roles of B Cells in Patients with Sepsis

Xijie Dong,  Hao Tu,  Shuang Qin,  Xiangjun Bai,  Fan Yang,  Zhanfei Li, 
  • First Published: 22 April 2023
Research Article
Open Access

Macrophages Phenotype Regulated by IL-6 Are Associated with the Prognosis of Platinum-Resistant Serous Ovarian Cancer: Integrated Analysis of Clinical Trial and Omics

Xiaoqing Wu,  Wenping Lu,  Chaojie Xu,  Cuihong Jiang,  Zhili Zhuo,  Ruipeng Wang,  Dongni Zhang,  Yongjia Cui,  Lei Chang,  Xi Zuo,  Ya’nan Wang,  Heting Mei,  Weixuan Zhang,  Mengfan Zhang,  Chen Li, 
  • First Published: 19 April 2023
Research Article
Open Access

Hotspots and Frontiers of Host Immune Response in Idiopathic Pulmonary Fibrosis: A Bibliometric and Scientific Visual Research from 2000 to 2022

Shirong Li,  Pengyue Zhao,  Chao Wang,  Yun Xia,  Haoyan Wang,  Wenjie Qi, 
  • First Published: 19 April 2023
Research Article
Open Access

Membrane and Soluble CD137 in Systemic Lupus Erythematosus: Role as Biomarkers for Disease Activity

Fulvia Ceccarelli,  Francesco Natalucci,  Alessandra Di Filippo,  Giulio Olivieri,  Chiara Napoletano,  Aurelia Rughetti,  Marianna Nuti,  Ilaria Grazia Zizzari,  Fabrizio Conti, 
  • First Published: 18 April 2023
Research Article
Open Access

Roles of Pyroptosis-Related Genes in the Diagnosis and Subtype Classification of Periodontitis

Xiaofan Cheng,  Yifang Hu,  Guan Gui,  Xiaoya Hu,  Jie Zhu,  Bowei Shi,  Shoushan Bu, 
  • First Published: 10 April 2023
Research Article
Open Access

Assessment of Functional Capacity of Immune System in Patients with Multiple Sclerosis using QuantiFERON Monitor

Zbysek Pavelek,  Ondrej Soucek,  Jan Krejsek,  Ilona Sejkorova,  Oldrich Vysata,  Blanka Klimová,  Francesco Angelucci,  Pavel Stourac,  Martin Valis,  Marek Peterka,  Lukáš Sobisek,  Michal Novotny, 
  • First Published: 07 April 2023
Research Article
Open Access

Identification of Hub Biomarkers and Immune and Inflammation Pathways Contributing to Kawasaki Disease Progression with RT-qPCR Verification

Hongjun Ba,  Lili Zhang,  Huimin Peng,  Xiufang He,  Yuese Lin,  Xuandi Li,  Shujuan Li,  Ling Zhu,  Youzhen Qin,  Xing Zhang,  Yao Wang, 
  • First Published: 06 April 2023
Research Article
Open Access

Aldehyde Dehydrogenase 2 Ameliorates LPS-Induced Acute Kidney Injury through Detoxification of 4-HNE and Suppression of the MAPK Pathway

Jifu Jin,  Rebecca Suchi Chang,  Sujuan Xu,  Guang Xia,  Jennifer Ming Jen Wong,  Yi Fang,  Ping Jia,  Xiaoqiang Ding, 
  • First Published: 06 April 2023
Research Article
Open Access

Multiple CD59 Polymorphisms in Chinese Patients with Mycobacterium tuberculosis Infection

Jie Tang,  Zhenzhen Zhao,  Juan Zhou,  Lin Jiao,  Wenjing Zhou,  Binwu Ying,  Yuwei Yang, 
  • First Published: 02 April 2023
Research Article
Open Access

Ubiquitin-Specific Protease 43 Impacts Pancreatic Ductal Adenocarcinoma Prognosis by Altering Its Proliferation and Infiltration of Surrounding Immune Cells

Ziqi Zhao,  Zhikun Lin,  Xin Guo,  Abdullah Al-danakh,  Hui He,  Henan Qin,  Chi Ma,  Ningning Zhang,  Guang Tan, 
  • First Published: 02 April 2023
Research Article
Open Access

Nasopharyngeal Carcinoma Subtype Discovery via Immune Cell Scores from Tumor Microenvironment

Yanbo Sun,  Yun Liu,  Hanqi Chu, 
  • First Published: 31 March 2023
Research Article
Open Access

c-Myb Dominates TBK1-Mediated Endotoxin Tolerance in Kupffer Cells by Negatively Regulating DTX4

Yi-Lin Wu,  Le-Han Pan,  Zhu-Jun Yi,  Wen-Feng Zhang,  Jian-Ping Gong, 
  • First Published: 31 March 2023
Research Article
Open Access

Cyr61 Mediates Angiotensin II-Induced Podocyte Apoptosis via the Upregulation of TXNIP

Jingxue Ma,  Ruiying Ma,  Xiaoyue Zhao,  Yingxiu Wang,  Shengxue Liao,  Cong Nong,  Fengling Lu,  Zhao Liang,  Junhui Huang,  Yan Huang,  Zhengxi Zhu,  Junjie Wang, 
  • First Published: 29 March 2023
Research Article
Open Access

Potential Targets and Mechanisms of Jiedu Quyu Ziyin Decoction for Treating SLE-GIOP: Based on Network Pharmacology and Molecular Docking

Jie Li,  Run-yu Chang,  Lin-feng Chen,  Su-hai Qian,  Rong-yun Wang,  Ji-le Lan,  Lin Huang,  Xing-hong Ding, 
  • First Published: 28 March 2023
Research Article
Open Access

Adjuvant Efficacy of the ECMS-Oil on Immune Responses against Bordetella bronchiseptica in Mice through the TLR2/MyD88/NF-κB Pathway

Chenwen Xiao,  Yee Huang,  Xuemei Cui,  Qiang Wei,  Quanan Ji,  Yan Liu,  Su Fei,  Yao Pan,  Xiangfei Xu,  Huang Pan,  Guolian Bao, 
  • First Published: 27 March 2023
Research Article
Open Access

circSPECC1 Promotes Proliferation and Migration of LNCaP Prostate Cancer Cells by Affecting Their Epithelial-Mesenchymal Transition

Fangmei Xie,  Jian Shen,  Zeping Han,  Wenfeng Luo,  Liyin Liao,  Jinhua He, 
  • First Published: 27 March 2023
Research Article
Open Access

miR-21-5p Inhibits Ferroptosis in Hepatocellular Carcinoma Cells by Regulating the AKT/mTOR Signaling Pathway through MELK

Zongqiang Hu,  Laibang Li,  Ma Li,  Xibing Zhang,  Yu Zhang,  Jianghua Ran,  Li Li, 
  • First Published: 24 March 2023
Research Article
Open Access

SERPINB4 Promotes Keratinocyte Inflammation via p38MAPK Signaling Pathway

Yanan Zhang,  Luling Wang,  Xiaoying Sun,  Fulun Li, 
  • First Published: 21 March 2023
Research Article
Open Access

Development of a Novel Recombinant Full-Length IgY Monoclonal Antibody against Human Thymidine Kinase 1 for Automatic Chemiluminescence Analysis on a Sandwich Biotin-Streptavidin Platform for Early Tumour Discovery

Xiangbin Wang,  Shan Li,  Rui Zhao,  Huijun Li,  Peng Gao,  Cuicui Jin,  Cong Fang,  Yongping Liu,  Ailian Hei,  Ji Zhou,  Jin Li,  Ellen He,  Sven Skog, 
  • First Published: 17 March 2023
Research Article
Open Access

Vascular Normalization Was Associated with Colorectal Tumor Regression upon Anti-PD-L1 Combinational Therapy

Yan Zhang,  Jiayan Gao,  Yan He,  Ziwei Qi,  Long Qian,  Wanpei Chen,  Haiyan Xu,  Yanhua Yue,  Xunyuan Mao,  Shuxin Guo,  Yan Zhou,  Shuru Zhou,  Songbing Qin,  Xueguang Zhang,  Yuhui Huang, 
  • First Published: 17 March 2023
Research Article
Open Access

Network-Based Method to Investigate the Promoted Cell Apoptosis Mechanisms of Oridonin in OSCC through the RNA-Transcriptome

Guohui Wu,  Yusheng Guo,  Yang Liu,  Xiangsheng Cai,  Tanggang Deng,  Tianchu Pei,  Long Huang,  Kai Chen,  Xuan Pan, 
  • First Published: 16 March 2023
Research Article
Open Access

The Potential Diagnostic Biomarkers for the IgG Subclass in Coal Workers’ Pneumoconiosis

Zhao-Guo Li,  Bai-Cun Li,  Zhi-Wei Li,  Hui-Yuan Hu,  Xia Ma,  Hong Cao,  Zhi-Hua Yu,  Hua-Ping Dai,  Jing Wang,  Chen Wang, 
  • First Published: 14 March 2023
Research Article
Open Access

Fecal Keratin 8 Is a Noninvasive and Specific Marker for Intestinal Injury in Necrotizing Enterocolitis

Kewei Wang,  Guozhong Tao,  Zhen Sun,  Jingjing Wei,  Junlin Liu,  Jordan Taylor,  Michelle Gibson,  Mirko Mostaghimi,  Misty Good,  Karl G. Sylvester, 
  • First Published: 14 March 2023
Research Article
Open Access

Immunohistochemical Features of MMP-9 and pSTAT1 in Granuloma Annulare and Sarcoidosis: A Comparative Study of 62 Cases

Ze Wu,  Linghui Li,  Hui Qu,  Rui-Qun Qi,  Jun Niu, 
  • First Published: 14 March 2023
Research Article
Open Access

Pollen Food Allergy Syndrome in Japanese Children and Adolescents: Risk Factors and Pollen Sensitisation

Masaya Kato,  Manabu Miyamoto,  Fumitaka Takayanagi,  Yusuke Ando,  Yuji Fujita,  Motoko Nakayama,  Shigemi Yoshihara, 
  • First Published: 09 March 2023
Research Article
Open Access

The SIX1/LDHA Axis Promotes Lactate Accumulation and Leads to NK Cell Dysfunction in Pancreatic Cancer

Wanli Ge,  Lingdong Meng,  Shouji Cao,  Chaoqun Hou,  Xiaole Zhu,  Dongya Huang,  Qiang Li,  Yunpeng Peng,  Kuirong Jiang, 
  • First Published: 08 March 2023
Research Article
Open Access

Necrostatin-1 Alleviates Diffuse Pulmonary Haemorrhage by Preventing the Release of NETs via Inhibiting NE/GSDMD Activation in Murine Lupus

Xinai Han,  Xiaoming Zhang,  Rui Song,  Shiqi Li,  Shujing Zou,  Quanguang Tan,  Tianyang Liu,  Shugeng Luo,  Zhe Wu,  Hongyu Jie,  Jinhong Wang, 
  • First Published: 01 March 2023
Research Article
Open Access

lncRNA HCG11 Promotes Colorectal Cancer Cell Malignant Behaviors via Sponging miR-26b-5p

Song Guo,  Bingtan Song,  Lin Li,  Hesheng Li,  Tao Yang,  Lianmeng Cao,  Jian Wang, 
  • First Published: 23 February 2023
Research Article
Open Access

Identification of B and T Cell Epitopes to Design an Epitope-Based Peptide Vaccine against the Cell Surface Binding Protein of Monkeypox Virus: An Immunoinformatics Study

Lincon Mazumder,  Md. Rakibul Hasan,  Kanij Fatema,  Shamima Begum,  Abul Kalam Azad,  Mohammad Ariful Islam, 
  • First Published: 22 February 2023
Research Article
Open Access

The Efficacy and Mechanism of Qinghua Jianpi Recipe in Inhibiting Canceration of Colorectal Adenoma Based on Inflammatory Cancer Transformation

Ting Liu,  Juping You,  Qingjian Gao,  Yufeng Zhang,  Wei Xu,  Desong Kong,  Li Chen,  Bao Yuan,  Haibing Hua, 
  • First Published: 15 February 2023
Review Article
Open Access

[Retracted] Relationship between Platelet-to-Lymphocyte Ratio and Lymphocyte-to-Monocyte Ratio with Spontaneous Preterm Birth: A Systematic Review and Meta-analysis

Liang Peng,  Baodi Cao,  Fangpeng Hou,  Baolin Xu,  Hong Zhou,  Luyi Liang,  Yu Jiang,  Xiaohui Wang,  Jingjian Zhou, 
  • First Published: 13 February 2023

Research Article
Open Access

Downregulation of miR-137 Facilitates CD4+ T Cell Pyroptosis in Systemic Lupus Erythematosus via Stimulating AMPK Pathway

Aimin Gong,  Long Mi,  Fangzhi Wei,  Yanping Zhuang,  Yitian Song,  Chengdan Pan,  Xuan Zhang,  Guiling Lin,  Zhiquan Wu,  Ying Liu, 
  • First Published: 09 February 2023
Research Article
Open Access

Exploration of Lipid Metabolism Alterations in Children with Active Tuberculosis Using UHPLC-MS/MS

Baixu Sun,  Fang Liu,  Qingqin Yin,  Tingting Jiang,  Min Fang,  Li Duan,  Shuting Quan,  Xue Tian,  Adong Shen,  Kaixia Mi,  Lin Sun, 
  • First Published: 09 February 2023
Research Article
Open Access

Characterization of Infiltrating Immune Cells and Secretory or Membrane-Associated Proteins in KRAS Lung Adenocarcinoma

Yunyi Bian,  Guoshu Bi,  Guangyao Shan,  Jiaqi Liang,  Qihai Sui,  Zhengyang Hu,  Qun Wang,  Yi Zhang,  Hong Fan, 
  • First Published: 06 February 2023
Research Article
Open Access

House Dust Mite and Cat Dander Extract Induce Asthma-Like Histopathology with an Increase of Mucosal Mast Cells in a Guinea Pig Model

Patricia Ramos-Ramírez,  Jielu Liu,  Sofia Mogren,  Joshua Gregory,  Malin Noreby,  Anne Petrén,  Ying Lei,  Henric Olsson,  Marianne van Hage,  Jukka Kervinen,  Lars Hellman,  Cecilia Andersson,  Gunnar Nilsson,  Mikael Adner, 
  • First Published: 31 January 2023
Research Article
Open Access

SEMA5A-PLXNB3 Axis Promotes PDAC Liver Metastasis Outgrowth through Enhancing the Warburg Effect

Kun Wang,  Min He,  Xin Fan,  Jian Zhou,  Jian Yang,  Lin Wang,  Zhihong Zhao,  Chun Dai,  Zixiang Zhang, 
  • First Published: 27 January 2023
Research Article
Open Access

Pyroptosis-Related Signature Predicts the Progression of Ulcerative Colitis and Colitis-Associated Colorectal Cancer as well as the Anti-TNF Therapeutic Response

Yumei Ning,  Kun Lin,  Jun Fang,  Xiaojia Chen,  Xinyi Hu,  Lan Liu,  Qiu Zhao,  Haizhou Wang,  Fan Wang, 
  • First Published: 27 January 2023
Research Article
Open Access

Clinical Significance of Different Profiles of anti-Ro Antibodies in Connective Tissue Diseases

Hai-Tao Yang,  Xiao-Ping Hong,  Jie-Wen Guo,  Xiao-Ling Zhong,  Rui Liao,  Cui-Lian Liu,  Li-Xiong Liu,  Kai Li,  Yu-Lan Chen,  Dong-Zhou Liu, 
  • First Published: 25 January 2023
Review Article
Open Access

Berberine in Sepsis: Effects, Mechanisms, and Therapeutic Strategies

Tingxia Lv,  Chunpan Zhang,  Lan Hu,  Chao Wang,  Shirong Li,  He Wang,  Wenjie Qi, 
  • First Published: 25 January 2023
Research Article
Open Access

Age-Related Changes in Female Murine Reproductive Mucosa with respect to γδ T Cell Presence

Katarzyna Skulska,  Anna Ewa Kędzierska,  Małgorzata Krzyżowska,  Grzegorz Chodaczek, 
  • First Published: 23 January 2023
Research Article
Open Access

The Expression of ARMCX1 in Gastric Cancer Contributes to Prognosis and Influences Chemotherapy

Changheng Lv,  Di Yang,  Donghu Zhang,  Jiajia Shen,  Zechen Wang,  Siyuan He,  Lingzhang Meng,  Jian Song,  Jingjie Zhao, 
  • First Published: 23 January 2023
Research Article
Open Access

Exosome-Associated Gene Signature for Predicting the Prognosis of Ovarian Cancer Patients

Zihan Zhu,  Rui Geng,  Yixin Zhang,  Jinhui Liu,  Jianling Bai, 
  • First Published: 23 January 2023
Research Article
Open Access

Coexpression of PD-L1/PD-1 with CXCR3/CD36 and IL-19 Increase in Extranodal Lymphoma

Manal Mohamed Saber, 
  • First Published: 23 January 2023
Research Article
Open Access

Drug Resistance of Mycobacterium tuberculosis Based on Whole-Genome Sequencing in the Yi Ethnic Group, Sichuan Province, China

Wenfeng Gao,  Xiaoru Chen,  Liang Yao,  Jing Li,  Yuan Gao,  Ting Li,  Yunkui Li,  Weina Wang,  Shu Zhang,  Jinge He, 
  • First Published: 23 January 2023
Research Article
Open Access

Identification of Adipogenesis Subgroups and Immune Infiltration Characteristics in Diabetic Peripheral Neuropathy

Yumin Lin,  Liyuan Qu,  Jintao Wu,  Meicen Pu,  Yijuan Huang,  Ying Cao, 
  • First Published: 19 January 2023
Research Article
Open Access

Activation of Most Toll-Like Receptors in Whole Human Blood Attenuates Platelet Deposition on Collagen under Flow

Y. Liu,  S. L. Diamond, 
  • First Published: 17 January 2023
Research Article
Open Access

Identification and Analysis of Potential Immune-Related Biomarkers in Endometriosis

Yanan He,  Jixin Li,  Yanjun Qu,  Liyuan Sun,  Xibo Zhao,  Han Wu,  Guangmei Zhang, 
  • First Published: 10 January 2023
Research Article
Open Access

Profiling of Peripheral TRBV and CD4+CD25+ Treg in CHB Patients with HBeAg SC during TDF Treatment

Jiezuan Yang,  Haifeng Lu,  Baikun Chen,  Lili Jiang,  Hua Zhang,  Ping Ye,  Linfeng Jin, 
  • First Published: 10 January 2023
Research Article
Open Access

FTY720 Attenuates LPS-Induced Inflammatory Bone Loss by Inhibiting Osteoclastogenesis via the NF-κB and HDAC4/ATF Pathways

Chongwei Chen,  Sujing Zong,  Zhenyu Wang,  Ruijia Yang,  Yanjing Guo,  Yunfei Wang,  Xinping Chen,  Yue Li,  Shaowei Wang, 
  • First Published: 06 January 2023
Research Article
Open Access

Differences in the Clinical Characteristics and 1-Year Mortality Rates of Patients with Dermatomyositis with anti-Jo-1 and anti-MDA5 Antibodies

Chao-Han Liu,  Chew-Teng Kor,  Ming-Hui Hung,  Kai-Hung Hsiao,  Yen-Huang Cheng,  Ya-Chih Tien, 
  • First Published: 04 January 2023