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Journal of Immunology Research

Journal of Immunology Research

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    Research Article
    Open Access
    oa

    Single-Cell Data and Weighted Correlation Network Analysis Revealed the Regulatory Mechanisms of Macrophages in Carotid Plaques

    Yakun Ding,  Xiaoyang Niu,  Peng Guo,  Bing Wang, 
    • 9987367
    • First Published: 21 July 2025
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    Review Article
    Open Access
    oa

    Epigenetic Regulation of B Cell Memory Formation: A Poised Model for B Cell Epigenetic Reprograming

    Carlos Valverde-Hernandez, 
    • 9328523
    • First Published: 17 July 2025
    • Abstract
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    Research Article
    Open Access
    oa

    Integrated Transcriptomic Analysis Provided Diagnostic and Pathophysiological Insights for Epilepsy

    Shuang Li,  Zhigang Wang,  Yake Zheng,  Yunqing Ma,  Zhi Huang,  Yajun Lian, 
    • 5925485
    • First Published: 15 July 2025
    • Abstract
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    Research Article
    Open Access
    oa

    Poxvirus Vectors Activate Human NK and MAIT Cells in a Type I Interferon, IL-18, and Monocyte-Dependent Manner

    Kombo F. N’guessan,  Zhanna Shubin,  Kawthar Machmach,  Johan K. Sandberg,  Julie A. Ake,  Sandhya Vasan,  Michael A. Eller,  Dominic Paquin-Proulx, 
    • 1203141
    • First Published: 12 July 2025
    • Abstract
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    Research Article
    Open Access
    oa

    4-Phenyl Butyric Acid (4-PBA) Suppresses Neutrophil Recruitment in a Murine Model of Acute Perinatal Inflammation

    Christian Gille,  Maylis Jungwirth,  Silvia Pezer,  Stefanie Dietz-Ziegler,  Natascha Köstlin-Gille,  Trim Lajqi, 
    • 2438058
    • First Published: 07 July 2025
    • Abstract
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    Review Article
    Open Access
    oa

    The Multifaceted Role of the IL-2 Cytokine Family in Melanoma: Mechanisms, Therapeutic Implications, and Immune Modulation

    Mona Daghaighei,  Samaneh Dodge,  Soheil Bolandi,  Boutros Youssef,  Niket Attarde,  Moein Maddahi,  Maryam Mostofi,  Reza Morovatshoar,  Mehrnaz Mostafavi,  Dejbakht Majid,  Mohammadamin Joulani,  Pegah Tamimi,  Malihe Sharafi,  Qumars Behfar,  Yasaman Ghodsi Boushehri,  Alireza Azani, 
    • 8890939
    • First Published: 02 July 2025
    • Abstract
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    Open Access
    oa

    Longitudinal Analysis of Traditional Inflammatory Markers (IL-6, CRP) Juxtaposed With Heparin-Binding Protein (HBP) and Serum Amyloid A Protein Component (SAA) During Acute Infection and Convalescence From COVID-19 Infection in the Context of Initial Viral Load and Markers of Tissue Destruction

    Ahmed Sayed Ahmed,  Mohamed A. Mahmoud,  Hossam Gad,  Mohamed Antar,  Abdelhamed Elgazar,  Vasishta Anil,  Daniel A. Diedrich,  Krzysztof Laudanski, 
    • 8881752
    • First Published: 28 June 2025
    • Abstract
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    Open Access
    oa

    Erratum to “Global Trends in Research of Amino Acid Metabolism in T Lymphocytes in Recent 15 Years: A Bibliometric Analysis”

    • 9813495
    • First Published: 24 June 2025

    This article corrects the following:

    • Global Trends in Research of Amino Acid Metabolism in T Lymphocytes in Recent 15 Years: A Bibliometric Analysis
      • Jiaona Xu, 
      • Yinan Yu, 
      • Shijie Li, 
      • Fanghui Qiu, 
      • Volume 2025Issue 1Journal of Immunology Research
      • First Published online: January 24, 2025
    • Full text
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    Research Article
    Open Access
    oa

    Macrophage Transcriptomic Alterations Driven by Alphavirus-Based Cancer Immunotherapy Vectors

    Ksenija Korotkaja,  Darija Lapina,  Zhanna Rudevica,  Anna Zajakina, 
    • 6573891
    • First Published: 13 June 2025
    • Abstract
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    Research Article
    Open Access
    oa

    The Molecular Mechanisms of Imatinib Treatment on Acute Lung Injury in Septic Mice Through Proteomic Technology

    Xiao Wang,  ZhiQing Zhou,  DuanYang Li,  BoYang Zhang,  XiaoLong Zong,  Xue Liang,  ZhenYu Li, 
    • 4526375
    • First Published: 09 June 2025
    • Abstract
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    Research Article
    Open Access
    oa

    Roles of Mitochondrial Fusion and Division in Harmine Derivative H-2-168-Induced Neurotoxicity

    Yuehong Gong,  Meichi Pan,  Hang Ren,  Dongling Peng,  Meiling Zhao,  Yicong Zhao,  Chunlin Luo,  Qin Ma,  Hao Wen,  Jianhua Wang, 
    • 6678026
    • First Published: 03 June 2025
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    Research Article
    Open Access
    oa

    Monoclonal Antibodies Against Vascular Endothelial Growth Factor A (VEGF-A) Reduce Synovitis, Bone Damage, and Osteogenesis in an SKG Mouse Model of Spondyloarthritis

    Marcin Czepiel,  Małgorzata Stec,  Anna Gąsiorek,  Anna Gałuszka,  Kornelia Kłosińska,  Joanna Kozieł,  Jarosław Czyż,  Jarosław Baran,  Przemysław Błyszczuk,  Maciej Siedlar,  Mariusz Korkosz, 
    • 8870895
    • First Published: 30 May 2025
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    Review Article
    Open Access
    oa

    Th17/Treg Cell Imbalance May Contribute to Spontaneous Preterm Labor

    Meiyi Xu,  Cunling Zhang,  Dan Wu,  Liying Yao,  Mengyuan Geng,  Shanshan Li,  Yuling Guo,  Qiushui Wang,  Zhuo Wei,  Wen Li, 
    • 8405365
    • First Published: 22 May 2025
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    Research Article
    Open Access
    oa

    Antiretroviral Therapy at Conception Leads to Lower Peripheral CD49a+ NK Cells and Higher SERPINB2

    Yanling Huo,  Jinhee Kim,  Deborah Kacanek,  Sadia Samer,  Elizabeth G. Livingston,  Elizabeth Stankiewicz Machado,  Elena Martinelli, 
    • 4771787
    • First Published: 21 May 2025
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    Open Access
    oa

    The Impact of Killer Cell Immunoglobulin-Like Receptors and Human Leukocyte Antigen-E, Human Leukocyte Antigen-G Polymorphisms on Innate Immunity and COVID-19 Severity

    Cigdem Kekik,  Sonay Temurhan,  Yeliz Ogret,  Behnoush Nasr Zanjani,  Demet Kıvanc,  Fatma Savran Oguz,  Murat Kose,  Fatma Betul Oktelik,  Gunnur Deniz, 
    • 6691437
    • First Published: 12 May 2025
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    Retraction
    Open Access
    oa

    RETRACTION: lncRNA PANTR1 Upregulates BCL2A1 Expression to Promote Tumorigenesis and Warburg Effect of Hepatocellular Carcinoma through Restraining miR-587

    Journal of Immunology Research, 
    • 9874823
    • First Published: 04 May 2025

    This article retracts the following:

    • lncRNA PANTR1 Upregulates BCL2A1 Expression to Promote Tumorigenesis and Warburg Effect of Hepatocellular Carcinoma through Restraining miR-587
      • Xirui Ma, 
      • Ziming Mao, 
      • Jing Zhu, 
      • Huifang Liu, 
      • Fengling Chen, 
      • Volume 2021Issue 1Journal of Immunology Research
      • First Published online: August 13, 2021
    • Full text
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    Research Article
    Open Access
    oa

    Exploring the Potential Link Between Autoimmune Diseases and Pan-Cancer: A Multidatabase Mendelian Randomization Analysis

    Chenguang Wang,  Zhiyong Liu,  Yuhao Zhou,  Yan He,  Yashu Zhang,  Shiqi Chen,  Wenqing Yang,  Lijun Fan, 
    • 6468979
    • First Published: 28 April 2025
    • Abstract
    • Full text
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    Review Article
    Open Access
    oa

    Progression in the In Vitro Macrophage Expansion

    Yunpeng Wei,  Jingzhao Yang,  Wenhong Zu,  Mengran Wang,  Yong Zhao, 
    • 9994439
    • First Published: 28 April 2025
    • Abstract
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    Research Article
    Open Access
    oa

    Evaluation of Immunostimulatory Effects of Bacterial Lysate Proteins on THP-1 Macrophages: Pro-inflammatory Cytokine Response and Proteomic Profiling

    Md. Mijanur Rahman,  Asma Talukder,  Md. Sifat Rahi,  Plabon Kumar Das,  I. Darren Grice,  Glen C. Ulett,  Ming Q. Wei, 
    • 2289241
    • First Published: 25 April 2025
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    Research Article
    Open Access
    oa

    Correlation Analysis of Human Immunological Indicators and Nosocomial Infections, Along With Evaluation Value for Prognosis

    Cai-jun Wu,  Jun Yan,  Li-ping Sun,  Lin-qin Ma,  Lan Li,  Jin Liu,  Jia-qi Zhang,  Yang Ren,  Wei Bi, 
    • 5539590
    • First Published: 24 April 2025
    • Abstract
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    Review Article
    Open Access
    oa

    Research Progress on the Immunological Correlation Between Papillary Thyroid Carcinoma and Hashimoto’s Thyroiditis

    Digui Fang,  Limei Zhou,  Biao Zheng, 
    • 7192808
    • First Published: 23 April 2025
    • Abstract
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    Research Article
    Open Access
    oa

    LINC00892 as a Prognostic Biomarker in Lung Adenocarcinoma: Role in Immune Infiltration and EMT Suppression

    Xinyu Luan,  Xuxing Peng,  Qinghua Hou,  Jixian Liu, 
    • 4341348
    • First Published: 22 April 2025
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    Research Article
    Open Access
    oa

    Bidirectional Interaction Between Chronic Kidney Disease and Porphyromonas gingivalis Infection Drives Inflammation and Immune Dysfunction

    Karina Adamowicz,  Andrea Sofia Lima Ribeiro,  Anna Golda,  Marta Wadowska,  Jan Potempa,  Christoph Schmaderer,  Hans-Joachim Anders,  Joanna Koziel,  Maciej Lech, 
    • 8355738
    • First Published: 17 April 2025
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    Research Article
    Open Access
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    In Silico Design and Characterization of a Multiepitope Vaccine Candidate Against Brucella canis Using a Reverse Vaccinology Approach

    Vicente Arriagada,  Alberto Osorio,  Crisleri Carrera-Naipil,  Carlos A. Villacis-Aguirre,  Cristian Escobar,  Nicolás Morales,  Danthe Villa,  Lien Mardones,  Dafne Pérez,  Macarena Jara,  Raúl E. Molina,  Ítalo Ferrari,  Sebastián Azocar,  Leonardo A. Gómez,  Ángel A. Oñate, 
    • 6348238
    • First Published: 15 April 2025
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    Review Article
    Open Access
    oa

    Exploring the Role of Cellular Interactions in the Colorectal Cancer Microenvironment

    Jiadai Tang,  Liuhan Chen,  Xin Shen,  Tingrong Xia,  Zhengting Li,  Xiaoying Chai,  Yao Huang,  Shaoqiong Yang,  Xinjun Peng,  Junbo Lai,  Rui Li,  Lin Xie, 
    • 4109934
    • First Published: 11 April 2025
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    Open Access
    oa

    Distribution of HLA-DRB1 Alleles in Patients With Antiphospholipid Syndrome and Their Association With Antiphospholipid Antibodies Presence and Damage Indexes

    Ewa Haladyj,  Barbara Stypinska,  Agata Matusiewicz,  Marzena Olesinska,  Agnieszka Paradowska-Gorycka, 
    • 2827348
    • First Published: 24 March 2025
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    Research Article
    Open Access
    oa

    Serum Proteomics of Experimental Malaria-Associated ARDS Reveals a Regulation of Acute-Phase Response Proteins

    Lívia Rosa-Fernandes,  Verônica Feijoli Santiago,  Yasmin da Silva-Santos,  Tissiane Tarosso Lopes,  Erika Paula Machado Peixoto,  Stefani Aparecida Minchio Rodrigues,  Claudio Romero Farias Marinho,  Giuseppe Palmisano,  Sabrina Epiphanio, 
    • 5642957
    • First Published: 23 March 2025
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    Open Access
    oa

    Identification of a Prognostic Signature Based on Tumor-Infiltrating B Lymphocyte mRNA in Head and Neck Squamous Cell Carcinoma

    Mingjun Zhang,  Qi Sun,  Yisong Yao,  Xi Chen,  Jiaxuan Li,  Ting Yuan,  Yakui Mou,  Yumei Li,  Xicheng Song, 
    • 9375885
    • First Published: 20 March 2025
    • Abstract
    • Full text
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    Research Article
    Open Access
    oa

    Metal Hypersensitivity in Patients With Failure of Joint Prosthesis Treatment

    Jana Bruna,  Jarmila Prochazkova,  Stepan Podzimek,  Lucie Himmlova,  Tatjana Janatova,  Alex Vinsu, 
    • 4319686
    • First Published: 10 March 2025
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    Research Article
    Open Access
    oa

    Plasma-Derived Neuronal Exosomal CircRNAs as Potential Biomarkers for Central Nervous System Infections

    Rui Zhang,  Bihan Deng,  Shuaibing Shi,  Geng Lu,  Jun Xia,  Hongwei Liang,  Fei Liu,  Shuangshuang Gu,  Jun Wang, 
    • 9363390
    • First Published: 25 February 2025
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    Open Access
    oa

    Chemically Induced Senescence Prompts Functional Changes in Human Microglia-Like Cells

    S. Armanville,  C. Tocco,  Z. Haj Mohamad,  D. Clarke,  R. Robitaille,  J. Drouin-Ouellet, 
    • 3214633
    • First Published: 24 February 2025
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    Open Access
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    Nucleated Red Blood Cells Secrete Haptoglobin to Induce Immunosuppressive Function in Monocytes

    Shusuke Takeuchi,  Satoshi Fujiyama,  Motomichi Nagafuji,  Miyuki Mayumi,  Makoto Saito,  Mana Obata-Yasuoka,  Hiromi Hamada,  Yayoi Miyazono,  Hidetoshi Takada, 
    • 8085784
    • First Published: 20 February 2025
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    Open Access
    oa

    FABP7 in Hepatic Macrophages Promotes Fibroblast Activation and CD4+ T-Cell Migration by Regulating M2 Polarization During Liver Fibrosis

    Hirofumi Miyazaki,  Tunyanat Wannakul,  Shuhan Yang,  Dandan Yang,  Ayano Karasawa,  Ai Shishido,  Ruizhu Cao,  Yui Yamamoto,  Yoshiteru Kagawa,  Shuhei Kobayashi,  Masaki Ogata,  Motoko Maekawa,  Yuji Owada, 
    • 6987981
    • First Published: 19 February 2025
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    Open Access
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    Risk Allele rs117026326-Mediated Alternative Splicing of GTF2I Promotes B Cell Proliferation in Primary Sjögren’s Syndrome

    Chaowen Luo,  Chaofeng Lian,  Jinlei Sun,  Liling Zhao,  Shuo Zhang,  Yongzhe Li,  Hua Chen,  Fengchun Zhang, 
    • 4821639
    • First Published: 18 February 2025
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    Open Access
    oa

    Durability of Functional SARS-CoV-2-Specific Immunological Memory and T Cell Response up to 8–9 Months Postrecovery From COVID-19

    Diptee Trimbake,  Dharmendra Singh,  Yogesh Gurav K.,  Prasad Babar,  Varsha Dange S.,  Anuradha S. Tripathy, 
    • 9743866
    • First Published: 10 February 2025
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    Open Access
    oa

    Unveiling the Interplay Between Dendritic Cells and Natural Killer Cells as Key Players in Leishmania Infection

    Ana Valério-Bolas,  Mafalda Meunier,  Armanda Rodrigues,  Joana Palma-Marques,  Rui Ferreira,  Inês Cardoso,  Lis Lobo,  Marta Monteiro,  Telmo Nunes,  Ana Armada,  Wilson T. Antunes,  Graça Alexandre-Pires,  Isabel Pereira da Fonseca,  Gabriela Santos-Gomes, 
    • 3176927
    • First Published: 10 February 2025
    • Abstract
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    Open Access
    oa

    Clinical Efficacy of Transcutaneous Electrical Nerve Stimulation (TENS) in Pediatric Functional Constipation: Impact on Immunological Indicators and Gut Microbiota

    Piao Guo,  Xue Ning Zhang,  Xin Yu Jin,  Wen Juan Xia,  Li Zhou,  Wei Song Sheng,  Dan Rong Zhu, 
    • 8888730
    • First Published: 05 February 2025
    • Abstract
    • Full text
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    Research Article
    Open Access
    oa

    Global Trends in Research of Amino Acid Metabolism in T Lymphocytes in Recent 15 Years: A Bibliometric Analysis

    Jiaona Xu,  Yinan Yu,  Shijie Li,  Fanghui Qiu, 
    • 3393342
    • First Published: 24 January 2025

    Correction(s) for this article

    • Erratum to “Global Trends in Research of Amino Acid Metabolism in T Lymphocytes in Recent 15 Years: A Bibliometric Analysis”
      • Volume 2025Issue 1Journal of Immunology Research
      • First Published online: June 24, 2025
    • Abstract
    • Full text
    • PDF
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    Review Article
    Open Access
    oa

    Advancements and Future Directions of Dual-Target Chimeric Antigen Receptor T-Cell Therapy in Preclinical and Clinical Studies

    Chenyun Zhang,  Haizhou Liu, 
    • 5845167
    • First Published: 15 January 2025
    • Abstract
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    Research Article
    Open Access
    oa

    NF-κB Inhibitory Activity of the Di-Hydroxy Derivative of Piperlongumine (PL-18)

    Yael Schlichter Kadosh,  Subramani Muthuraman,  Ariel Kushmaro,  Rajendran Saravana Kumar,  Jacob Gopas, 
    • 9915695
    • First Published: 08 January 2025
    • Abstract
    • Full text
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    Open Access
    oa

    Immune Tolerance Regulation Is Critical to Immune Homeostasis

    Lei Han,  Tianxiang Wu,  Qin Zhang,  Anning Qi,  Xiaohui Zhou, 
    • 5006201
    • First Published: 07 January 2025
    • Abstract
    • Full text
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