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    Annals of Neurology: Volume 94, Issue 2

    C1, i-vi, 211-415
    August 2023
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Free Access

Annals of Neurology: Volume 94, Number 2, August 2023

  • Page: C1
  • First Published: 26 July 2023

Issue Information

Free Access

Issue Information

  • Pages: i-vi
  • First Published: 26 July 2023

Review

Open Access

When Alzheimer's is LATE: Why Does it Matter?

Peter T. Nelson MD, PhD,  Julie A. Schneider MD, MS,  Gregory A. Jicha MD, PhD,  Michael Tran Duong PhD,  David A. Wolk MD, 
  • Pages: 211-222
  • First Published: 28 May 2023

Research Articles

Markers of Vitamin B12 Status in Relation to Cerebrospinal Fluid Biomarkers of Alzheimer's Disease and Cognitive Performance

Babak Hooshmand MD, PhD, MPH,  Franziska Appold MD,  Patrick Fissler PhD,  Robert Perneczky MD, PhD,  Markus Otto MD,  Hayrettin Tumani MD,  Miia Kivipelto MD, PhD,  Christine A. F. von Arnim MD, 
  • Pages: 223-231
  • First Published: 12 May 2023

Associations of VGF with Neuropathologies and Cognitive Health in Older Adults

Lei Yu PhD,  Vladislav A. Petyuk PhD,  Katia de Paiva Lopes PhD,  Shinya Tasaki PhD,  Vilas Menon PhD,  Yanling Wang PhD,  Julie A. Schneider MD,  Philip L. De Jager MD, PhD,  David A. Bennett MD, 
  • Pages: 232-244
  • First Published: 13 May 2023

Retromer Proteins Reduced in Down Syndrome and the Dp16 Model: Impact of APP Dose and Preclinical Studies of a γ-Secretase Modulator

Xu-Qiao Chen PhD,  Mariko Sawa PhD,  Ann Becker BA,  Dmitry Karachentsev PhD,  Xinxin Zuo PhD,  Kevin D. Rynearson PhD,  Rudolph E. Tanzi PhD,  William C. Mobley MD, PhD, 
  • Pages: 245-258
  • First Published: 11 April 2023
Open Access

A Comparison Between Early Presentation of Dementia with Lewy Bodies, Alzheimer's Disease, and Parkinson's Disease: Evidence from Routine Primary Care and UK Biobank Data

Thomas Nedelec PhD,  Baptiste Couvy-Duchesne PhD,  Aube Darves-Bornoz BSc,  Raphaël Couronne PhD,  Fleur Monnet MSc,  Laurène Gantzer MSc,  Béranger Lekens MSc,  Yeda Wu MD, PhD,  Nicolas Villain MD, PhD,  Anette Schrag MD, PhD,  Stanley Durrleman PhD,  Jean-Christophe Corvol MD, PhD, 
  • Pages: 259-270
  • First Published: 25 April 2023
A Comparison Between Early Presentation of Dementia with Lewy Bodies, Alzheimer's Disease, and Parkinson's Disease: Evidence from Routine Primary Care and UK Biobank Data

Connectivity Profile for Subthalamic Nucleus Deep Brain Stimulation in Early Stage Parkinson Disease

Mallory L. Hacker PhD, MSCI,  Nanditha Rajamani MSc,  Clemens Neudorfer MD,  Barbara Hollunder MSc,  Simon Oxenford,  Ningfei Li PhD,  Alice L. Sternberg ScM,  Thomas L. Davis MD,  Peter E. Konrad MD, PhD,  Andreas Horn MD, PhD,  David Charles MD, 
  • Pages: 271-284
  • First Published: 13 May 2023

Serum Alpha and Beta-CGRP Levels in Chronic Migraine Patients Before and After Monoclonal Antibodies Against CGRP or its Receptor

Gabriel Gárate BBiot,  Vicente González-Quintanilla MD, PhD,  Andrea González MD,  Marta Pascual MD,  Sara Pérez-Pereda MD, PhD,  Jorge Madera MD,  Julio Pascual MD, PhD, 
  • Pages: 285-294
  • First Published: 11 April 2023
Open Access

Impact of Clinician Training Background and Stroke Location on Bedside Diagnostic Test Accuracy in the Acute Vestibular Syndrome – A Meta-Analysis

Alexander A. Tarnutzer MD,  Daniel Gold MD,  Zheyu Wang PhD,  Karen A. Robinson PhD,  Jorge C. Kattah MD,  Georgios Mantokoudis MD,  Ali S. Saber Tehrani MD,  David S. Zee MD,  Jonathan A. Edlow MD,  David E. Newman-Toker MD, PhD, 
  • Pages: 295-308
  • First Published: 11 April 2023
Open Access

Intravenous Thrombolysis 4.5–9 Hours After Stroke Onset: A Cohort Study from the TRISP Collaboration

Valerian L. Altersberger MD,  Gerli Sibolt MD,  Lukas S. Enz MD, PhD,  Christian Hametner MD,  Jan F. Scheitz MD,  Hilde Henon MD,  Guido Bigliardi MD,  Davide Strambo MD,  Nicolas Martinez-Majander MD,  Lotte J. Stolze MD,  Mirjam R. Heldner MD,  Ilaria Grisendi MD,  Dejana R. Jovanovic MD, PhD,  Yannick Bejot MD, PhD,  Alessandro Pezzini MD,  Ronen R. Leker MD,  Georg Kägi MD,  Susanne Wegener MD,  Carlo W. Cereda MD,  Georges Ntaios PhD,  Gian Marco De Marchis MD, MSc,  Leo H. Bonati MD,  Marios Psychogios MD,  Philippe Lyrer MD,  Silja Räty MD,  Marjaana Tiainen MD, PhD,  Anke Wouters MD, PhD,  François Caparros MD,  Miriam Heyse MD,  Hebun Erdur MD,  Visnja Padjen PhD,  Marialuisa Zedde MD,  Marcel Arnold MD,  Paul J. Nederkoorn MD, PhD,  Patrik Michel MD,  Andrea Zini MD, FESO,  Charlotte Cordonnier PhD,  Christian H. Nolte MD,  Peter A. Ringleb MD,  Sami Curtze PhD,  Stefan T. Engelter MD,  Henrik Gensicke MD, on behalf of the TRISP collaborators , 
  • Pages: 309-320
  • First Published: 28 April 2023

Perioperative Acute Ischemic Stroke in Patients with Atrial Fibrillation

Liqi Shu MD,  Wei Jiang MD,  Han Xiao MS,  Nils Henninger MD, PhD,  Thanh N. Nguyen MD,  James E. Siegler MD,  Adam de Havenon MD, MS,  Eric D. Goldstein MD,  Daniel Mandel MD,  Maheen Rana MD,  Fawaz Al-Mufti MD,  Jennifer Frontera MD,  Karen Furie MD,  Shadi Yaghi MD, 
  • Pages: 321-329
  • First Published: 15 May 2023

Neuro-Images

Free Access

Cinematic Rendering of Extracranial to Intracranial Arterial Bypass

Arsany Hakim MD,  David Bervini MD, MAdvSurg, 
  • Pages: 330-331
  • First Published: 22 June 2023

Research Articles

KCNT2-Related Disorders: Phenotypes, Functional, and Pharmacological Properties

Maria Cristina Cioclu MD,  Ilaria Mosca PhD,  Paolo Ambrosino PhD,  Deborah Puzo MSc,  Allan Bayat MD, PhD,  Saskia B. Wortmann MD, PhD,  Johannes Koch MD,  Vincent Strehlow MD,  Kentaro Shirai MD,  Naomichi Matsumoto MD, PhD,  Stephan J. Sanders MD, PhD,  Vincent Michaud MD,  Marine Legendre MD, PhD,  Antonella Riva MD,  Pasquale Striano MD, PhD,  Hiltrud Muhle MD,  Manuela Pendziwiat MSc,  Gaetan Lesca MD, PhD,  Giuseppe Donato Mangano MD,  Rosaria Nardello MD,  KCNT2-study group ,  Johannes R. Lemke MD,  Rikke S. Møller PhD,  Maria Virginia Soldovieri PhD,  Guido Rubboli MD,  Maurizio Taglialatela MD, PhD, 
  • Pages: 332-349
  • First Published: 16 April 2023
Open Access

White Matter Changes after Neurobehavioral Therapy for Functional Seizures

Christina Mueller PhD,  Adam M. Goodman PhD,  Jane B. Allendorfer PhD,  Rodolphe Nenert PhD,  Tyler E. Gaston MD,  Leslie E. Grayson MD,  Stephen Correia PhD,  Noah S. Philip MD,  W. Curt LaFrance Jr MD, MPH,  Jerzy P. Szaflarski MD, PhD, 
  • Pages: 350-365
  • First Published: 21 April 2023
Open Access

Positron Emission Tomography with [18F]-DPA-714 Unveils a Smoldering Component in Most Multiple Sclerosis Lesions which Drives Disease Progression

Mariem Hamzaoui PhD,  Jeanne Garcia MD,  Giacomo Boffa MD, PhD,  Andrea Lazzarotto MD, PhD,  Martina Absinta MD, PhD,  Vito A.G. Ricigliano MD, PhD,  Theodore Soulier MD, PhD,  Matteo Tonietto PhD,  Philippe Gervais PhD,  Anne Bissery MD,  Céline Louapre MD, PhD,  Michel Bottlaender PhD,  Benedetta Bodini MD, PhD,  Bruno Stankoff MD, PhD, 
  • Pages: 366-383
  • First Published: 11 April 2023
Open Access

Shared Genetic Risk Factors for Multiple Sclerosis/Psoriasis Suggest Involvement of Interleukin-17 and Janus Kinase–Signal Transducers and Activators of Transcription Signaling

Matthew T. Patrick PhD,  Rajan P. Nair PhD,  Kevin He PhD,  Philip E. Stuart MS,  Allison C. Billi MD, PhD,  Xiang Zhou PhD,  Johann E. Gudjonsson MD, PhD,  Jorge R. Oksenberg PhD,  James T. Elder MD, PhD,  Lam C. Tsoi PhD, 
  • Pages: 384-397
  • First Published: 01 May 2023
Open Access

Post-Translational Modifications of the DUX4 Protein Impact Toxic Function in FSHD Cell Models

Renatta N. Knox MD, PhD,  Jocelyn O. Eidahl PhD,  Lindsay M. Wallace PhD,  Sarah G. Choudury PhD,  Afrooz Rashnonejad Msc, PhD,  Katelyn Daman PhD,  Matthew J. Guggenbiller BS,  Nizar Y. Saad PhD,  Michael E. Hoover PhD,  Liwen Zhang PhD,  Owen E. Branson PhD,  Charles P. Emerson Jr PhD,  Michael A. Freitas PhD,  Scott Q. Harper PhD, 
  • Pages: 398-413
  • First Published: 26 April 2023

Letters/Replies

Suvorexant for Preventing Alzheimer's Disease

Tomoyuki Kawada MD, 
  • Page: 414
  • First Published: 27 June 2023

Reply to Suvorexant for Preventing Alzheimer's Disease

Brendan P. Lucey MD, MSCI,  Randall J. Bateman MD, 
  • Pages: 414-415
  • First Published: 28 June 2023