Highlights

• Hypertension and diabetes are well-known major risk factors for coronary heart disease and diabetes is associated with increased need for repeat revascularization after stent implantation.
• In this study, the cumulative incidences of any repeat revascularization, target lesion revascularization (TLR), and target vessel revascularization (TVR) in the diabetes only group were significantly higher than the hypertension only group after risk adjustment.
• However, the cumulative incidences of major adverse cardiac events (MACEs), all-cause death, and recurrent myocardial infarction (Re-MI) were similar between these two groups.

Highlights A nested, nationwide, propensity-matched cohort study was carried out using the Clinical Practice Research Datalink with 1186 patients with no past history of ASCVD, half of whom had undergone bariatric surgery. Bariatric surgery was associated with improved ASCVD outcomes and lower mortality, highlighting a potential prognostic role of the surgery in patients with obesity and T2DM.

Highlights

• Even without progressing to type 2 diabetes, gestational hyperglycemia is associated with an increased risk of cardiovascular disease (CVD).
• The association between gestational hyperglycemia and CVD risk could be modified by lifestyle factors and hypertension.
• Subsequent blood pressure management and lifestyle intervention for women with gestational hyperglycemia are important approaches to prevent CVD.

Highlights

• The results of this paper is a post-hoc analysis of the original Da Qing Prevention Study.
• The findings showed that hypertension per se not only led to a higher incidence of cardio-cerebral-vascular disease, but also increased the risk of cardiovascular disease events by accelerating the development of diabetes among subjects with impaired glucose tolerance.
• It suggested that an individualized intervention targeting to control hypertension together with preventing the development of diabetes may favor the reduction of the diabetes-related macro-complications among the impaired glucose tolerance population with hypertension.

Highlights

• Fetal and early childhood exposure to the Chinese famine exacerbated risk of CVD due to diabetes.
• The targeting of early life nutrition should be considered as an important long-term strategy to prevent CVD, especially in areas affected by famine and other natural disasters.

Highlights

• Prior studies have reported an association between cardiovascular disease and risk of incident diabetes mellitus. However, factors that may explain the association remain unclear.
• Using propensity score matching, we reinforced the concern that cardiovascular disease may increase the risk of developing diabetes mellitus.
• We further showed that the association between cardiovascular disease and incident diabetes mellitus was partially explained by cardiovascular medications such as beta-blockers, statins, and diuretics.