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    2020
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[Retracted] VGLL4 Protects against Oxidized-LDL-Induced Endothelial Cell Dysfunction and Inflammation by Activating Hippo-YAP/TEAD1 Signaling Pathway

Kaicheng Xu,  Haomin Zhao,  Xiaolei Qiu,  Xiwen Liu,  Fucheng Zhao,  Yue Zhao, 
  • First Published: 30 December 2020

Research Article
Open Access

A Metabolic Gene Signature to Predict Overall Survival in Head and Neck Squamous Cell Carcinoma

Zeng-Hong Wu,  Yun Tang,  Yue Zhou, 
  • First Published: 30 December 2020
Research Article
Open Access

Inhibition of Peptidyl Arginine Deiminase-4 Prevents Renal Ischemia-Reperfusion-Induced Remote Lung Injury

Mingjun Du,  Lei Yang,  Jianmin Gu,  Jiawei Wu,  Yiwen Ma,  Tao Wang, 
  • First Published: 30 December 2020
Research Article
Open Access

The Monocyte-to-Lymphocyte Ratio at Hospital Admission Is a Novel Predictor for Acute Traumatic Intraparenchymal Hemorrhage Expansion after Cerebral Contusion

Jiangtao Sheng,  Tian Li,  Dongzhou Zhuang,  Shirong Cai,  Jinhua Yang,  Faxiu Ding,  Xiaoxuan Chen,  Fei Tian,  Mindong Huang,  Lianjie Li,  Kangsheng Li,  Weiqiang Chen, 
  • First Published: 29 December 2020
Research Article
Open Access

Oxidative and/or Inflammatory Thrust Induced by Silver Nanoparticles in Rabbits: Effect of Vitamin E or NSAID Administration on Semen Parameters

Collodel Giulia,  Mattioli Simona,  Moretti Elena,  Cerretani Daniela,  Micheli Lucia,  Fiaschi Anna Ida,  Menchetti Laura,  Brecchia Gabriele,  Castellini Cesare, 
  • First Published: 28 December 2020
Research Article
Open Access

Association of Plasma C1q/TNF-Related Protein 3 (CTRP3) in Patients with Atrial Fibrillation

Liwen Chen,  Shuwang Liu,  Wei Xu,  Yuan Zhang,  Jin Bai,  Lei Li,  Ming Cui,  Lijie Sun, 
  • First Published: 28 December 2020
Research Article
Open Access

Early T-Cell Precursor Leukemia Has a Higher Risk of Induction-Related Infection among T-Cell Acute Lymphoblastic Leukemia in Adult

Kangyu Huang,  Min Dai,  Qiuli Li,  Nannan Liu,  Dainan Lin,  Qiang Wang,  Xuan Zhou,  Zhixiang Wang,  Ya Gao,  Hua Jin,  Xiaoli Liu,  Qifa Liu,  Hongsheng Zhou, 
  • First Published: 24 December 2020
Research Article
Open Access

Beneficial Effects of Rosmarinic Acid on IPEC-J2 Cells Exposed to the Combination of Deoxynivalenol and T-2 Toxin

Judit Mercédesz Pomothy,  Réka Fanni Barna,  Erzsébet Anna Pászti,  Ákos Babiczky,  Áron Szóládi,  Ákos Jerzsele,  Erzsébet Pásztiné Gere, 
  • First Published: 22 December 2020
Research Article
Open Access

Monocyte Chemotactic Protein 1-Induced Protein 1 Is Highly Expressed in Inflammatory Bowel Disease and Negatively Regulates Neutrophil Activities

Jian Lin,  Gengfeng Li,  Chunjin Xu,  Huiying Lu,  Cui Zhang,  Zhi Pang,  Zhanju Liu, 
  • First Published: 22 December 2020
Research Article
Open Access

C1q/TNF-Related Protein 9 Inhibits Coxsackievirus B3-Induced Injury in Cardiomyocytes through NF-κB and TGF-β1/Smad2/3 by Modulating THBS1

Kebei Liu,  Juan Wang,  Xinru Gao,  Wei Ren, 
  • First Published: 21 December 2020
Research Article
Open Access

Leptin Receptor Deficiency Protects Mice against Chronic Cerebral Hypoperfusion-Induced Neuroinflammation and White Matter Lesions

Yu Du,  Yufei Song,  Xiaojie Zhang,  Yan Luo,  Wenying Zou,  Jiawei Zhang,  Jianliang Fu, 
  • First Published: 18 December 2020
Research Article
Open Access

Therapeutic Effect of Ginsenoside Rd on Experimental Autoimmune Encephalomyelitis Model Mice: Regulation of Inflammation and Treg/Th17 Cell Balance

Bo Jin,  Chixiao Zhang,  Yu Geng,  Mei Liu, 
  • First Published: 18 December 2020
Research Article
Open Access

Nicotine Synergizes with High-Fat Diet to Induce an Anti-Inflammatory Microenvironment to Promote Breast Tumor Growth

Thalia Jimenez,  Theodore Friedman,  Jaydutt Vadgama,  Vineeta Singh,  Alexandria Tucker,  Javier Collazo,  Satyesh Sinha,  Amiya Sinha Hikim,  Rajan Singh,  Shehla Pervin, 
  • First Published: 14 December 2020
Research Article
Open Access

The Prognosis Role of AST/ALT (De Ritis) Ratio in Patients with Adult Secondary Hemophagocytic Lymphohistiocytosis

Guangli Yin,  Changfeng Man,  Shengen Liao,  Hongxia Qiu, 
  • First Published: 08 December 2020
Research Article
Open Access

Dextromethorphan Suppresses Lipopolysaccharide-Induced Epigenetic Histone Regulation in the Tumor Necrosis Factor-α Expression in Primary Rat Microglia

Yung-Ning Yang,  Yu-Chen S. H. Yang,  Pei-Ling Wu,  Chun-Hwa Yang,  Kuang-Che Kuo,  San-Nan Yang, 
  • First Published: 08 December 2020
Corrigendum
Open Access

Corrigendum to “Protective Effects of Pretreatment with Oleanolic Acid in Rats in the Acute Phase of Hepatic Ischemia-Reperfusion Injury: Role of the PI3K/Akt Pathway”

Bo Gui,  Fuzhou Hua,  Jie Chen,  Zeping Xu,  Hongbin Sun,  Yanning Qian, 
  • First Published: 07 December 2020

Research Article
Open Access

Cryptococcus neoformans Secretes Small Molecules That Inhibit IL-1β Inflammasome-Dependent Secretion

Pedro Henrique Bürgel,  Clara Luna Marina,  Pedro H. V. Saavedra,  Patrícia Albuquerque,  Stephan Alberto Machado de Oliveira,  Paulo Henrique de Holanda Veloso Janior,  Raffael Araújo de Castro,  Heino M. Heyman,  Carolina Coelho,  Radames J. B. Cordero,  Arturo Casadevall,  Joshua D. Nosanchuk,  Ernesto S. Nakayasu,  Robin C. May,  Aldo Henrique Tavares,  Anamelia Lorenzetti Bocca, 
  • First Published: 07 December 2020
Research Article
Open Access

Detection of CD39 and a Highly Glycosylated Isoform of Soluble CD73 in the Plasma of Patients with Cervical Cancer: Correlation with Disease Progression

Ricardo Muñóz-Godínez,  María de Lourdes Mora-García,  Benny Weiss-Steider,  Juan José Montesinos-Montesinos,  Adriana del Carmen Aguilar-Lemarroy,  Rosario García-Rocha,  Jorge Hernández-Montes,  Christian Azucena Don-López,  Luis Roberto Ávila-Ibarra,  Daniela Berenice Torres-Pineda,  Gabriela Molina-Castillo,  Rommel Chacón-Salinas,  Luis Vallejo-Castillo,  Sonia Mayra Pérez-Tapia,  Alberto Monroy-García, 
  • First Published: 07 December 2020
Review Article
Open Access

COVID-19 and Neutrophils: The Relationship between Hyperinflammation and Neutrophil Extracellular Traps

Leandro Borges,  Tania Cristina Pithon-Curi,  Rui Curi,  Elaine Hatanaka, 
  • First Published: 04 December 2020
Research Article
Open Access

Investigation of Cytotoxicity, Oxidative Stress, and Inflammatory Responses of Tantalum Nanoparticles in THP-1-Derived Macrophages

Li Zhang,  El-Mustapha Haddouti,  Hannes Beckert,  Ralf Biehl,  Shyam Pariyar,  Julian M. Rüwald,  Xian Li,  Max Jaenisch,  Christof Burger,  Dieter C. Wirtz,  Koroush Kabir,  Frank A. Schildberg, 
  • First Published: 04 December 2020
Research Article
Open Access

Free Fatty Acids and Their Inflammatory Derivatives Affect BDNF in Stroke Patients

Dariusz Kotlega,  Agnieszka Zembron-Lacny,  Barbara Morawin,  Monika Golab-Janowska,  Przemyslaw Nowacki,  Malgorzata Szczuko, 
  • First Published: 03 December 2020
Research Article
Open Access

Helminthostachys zeylanica Water Extract Ameliorates Airway Hyperresponsiveness and Eosinophil Infiltration by Reducing Oxidative Stress and Th2 Cytokine Production in a Mouse Asthma Model

Wen-Chung Huang,  Nai-Chun Ting,  Yu-Ling Huang,  Li-Chen Chen,  Chwan-Fwu Lin,  Chian-Jiun Liou, 
  • First Published: 02 December 2020
Research Article
Open Access

High-Fructose Diet Increases Inflammatory Cytokines and Alters Gut Microbiota Composition in Rats

Yong Wang,  Wentao Qi,  Ge Song,  Shaojie Pang,  Zhenzhen Peng,  Yong Li,  Panli Wang, 
  • First Published: 30 November 2020
Research Article
Open Access

Tetrandrine Inhibits Titanium Particle-Induced Inflammatory Osteolysis through the Nuclear Factor-κB Pathway

Zige Liu,  Yan Li,  Fengying Guo,  Chen Zhang,  Guorui Song,  Jiahao Yang,  Desheng Chen, 
  • First Published: 29 November 2020
Research Article
Open Access

Glycogen Synthase Kinase 3β Promotes Postoperative Cognitive Dysfunction by Inducing the M1 Polarization and Migration of Microglia

Jingjin Li,  Chonglong Shi,  Zhengnian Ding,  Wenjie Jin, 
  • First Published: 28 November 2020
Research Article
Open Access

Atopic Dermatitis and Psoriasis as Overlapping Syndromes

A. Bozek,  M. Zajac,  M. Krupka, 
  • First Published: 28 November 2020
Research Article
Open Access

Effects of Dietary Histidine on Growth Performance, Serum Amino Acids, and Intestinal Morphology and Microbiota Communities in Low Protein Diet-Fed Piglets

Meng Kang,  Jie Yin,  Jie Ma,  Xin Wu,  Ke Huang,  Tiejun Li,  Long Ouyang, 
  • First Published: 28 November 2020
Research Article
Open Access

Neutrophil-Lymphocyte Ratio in Predicting Infective Endocarditis: A Case-Control Retrospective Study

Ying Chen,  Liang-jun Ye,  Yue Wu,  Bing-zheng Shen,  Fan Zhang,  Qiang Qu,  Jian Qu, 
  • First Published: 28 November 2020
Research Article
Open Access

IL-33 Mediates Lung Inflammation by the IL-6-Type Cytokine Oncostatin M

Fernando Botelho,  Anisha Dubey,  Ehab A. Ayaub,  Rex Park,  Ashley Yip,  Allison Humbles,  Roland Kolbeck,  Carl D. Richards, 
  • First Published: 28 November 2020
Corrigendum
Open Access

Corrigendum to “I-alowCD11bhigh DC Regulates the Immune Response in the Eyes of Experimental Autoimmune Uveitis”

Yu Zhao,  Jingwen Wang,  Zhang Min,  Li Peng,  Shuhong Qi,  Wei Lin, 
  • First Published: 28 November 2020

Research Article
Open Access

High Erythropoiesis Resistance Index Is a Significant Predictor of Cardiovascular and All-Cause Mortality in Chinese Maintenance Hemodialysis Patients

Xiangxue Lu,  Jialing Zhang,  Shixiang Wang,  Qian Yu,  Han Li, 
  • First Published: 26 November 2020
Research Article
Open Access

Inflammatory-Related Clinical and Metabolic Outcomes in COVID-19 Patients

Maria Martinez-Urbistondo,  Alberto Mora-Vargas,  Esther Expósito-Palomo,  Raquel Castejón,  M. Jesús Citores,  Silvia Rosado,  Carmen de Mendoza,  Isolina Baños,  Ana Fernández-Cruz,  Lidia Daimiel,  Rodrigo San-Cristóbal,  Juan Antonio Vargas,  J. Alfredo Martinez, 
  • First Published: 26 November 2020
Research Article
Open Access

Total Glucosides of Paeony Alleviate Cell Apoptosis and Inflammation by Targeting the Long Noncoding RNA XIST/MicroRNA-124-3p/ITGB1 Axis in Renal Ischemia/Reperfusion Injury

Fang Chen,  Yi Hu,  Yuetao Xie,  Zonghui Zhao,  Lin Ma,  Zhili Li,  Wanlong Tan, 
  • First Published: 25 November 2020
Review Article
Open Access

Inflammatory Response, a Key Pathophysiological Mechanism of Obesity-Induced Depression

Shu-Lin Shao,  Da-Qian Liu,  Bo Zhang,  Shu-Ming Huang, 
  • First Published: 24 November 2020
Research Article
Open Access

P-MAPA, a Fungi-Derived Immunomodulatory Compound, Induces a Proinflammatory Response in a Human Whole Blood Model

Mariana Torrente Gonçalves,  Carla Cristina Squaiella-Baptistão,  Giselle Pidde,  Priscila Hess Lopes,  Iseu da Silva Nunes,  Denise V. Tambourgi, 
  • First Published: 24 November 2020
Research Article
Open Access

Cangfudaotan Decoction Alleviates Insulin Resistance and Improves Follicular Development in Rats with Polycystic Ovary Syndrome via IGF-1-PI3K/Akt-Bax/Bcl-2 Pathway

Chenye Wang,  Caifei Ding,  Zhoujia Hua,  Chunyue Chen,  Jia Yu, 
  • First Published: 24 November 2020
Research Article
Open Access

Lipoxin A4 Reduces Ventilator-Induced Lung Injury in Rats with Large-Volume Mechanical Ventilation

Qi Wang,  Guang-xiao Xu,  Qi-hang Tai,  Yan Wang, 
  • First Published: 23 November 2020
Research Article
Open Access

Changes in Peripheral Blood Neutrophils, Lymphocytes and IL-10 in Children with Kawasaki Disease from Different Age Groups Undergoing Intravenous Immunoglobulin: A Retrospective Study

Chun Zhang,  Xuan Zhang,  Jia Shen,  Xiaotong Lu,  Jian Zhang,  Sun Chen, 
  • First Published: 19 November 2020
Research Article
Open Access

Contribution of Connexin Hemichannels to the Pathogenesis of Acute Lung Injury

Shuaiwei Wang,  Yafang Sun,  Yu Bai,  Nannan Zhou,  Na Chen,  Edmund J. Miller,  Yijie Zhang,  Wei Li, 
  • First Published: 18 November 2020
Research Article
Open Access

The Effects of Targeted Temperature Management on Oxygen-Glucose Deprivation/Reperfusion-Induced Injury and DAMP Release in Murine Primary Cardiomyocytes

Giang Tong,  Phuong D. Lam,  Franka Brey,  Jana Krech,  Sylvia J. Wowro,  Nalina N. A. von Garlen,  Felix Berger,  Katharina R. L. Schmitt, 
  • First Published: 18 November 2020
Review Article
Open Access

Immunometabolism, Micronutrients, and Bariatric Surgery: The Use of Transcriptomics and Microbiota-Targeted Therapies

Shannon Galyean,  Dhanashree Sawant,  Andrew C. Shin, 
  • First Published: 17 November 2020
Research Article
Open Access

Effects of Urate-Lowering Therapy on Risk of Hyperlipidemia in Gout by a Population-Based Cohort Study and on In Vitro Hepatic Lipogenesis-Related Gene Expression

Yi-Jen Fang,  Tien-Yuan Wu,  Cheng-Li Lin,  Chih-Yang Su,  Jia-Rong Li,  Yun-Lung Chung,  Ni Tien,  Yun-Ping Lim, 
  • First Published: 16 November 2020
Research Article
Open Access

The Change of Systemic Immune-Inflammation Index Independently Predicts Survival of Colorectal Cancer Patients after Curative Resection

Qingqing Chen,  Haohao Wu,  Xinwei Guo,  Ke Gu,  Wenjie Wang,  Xiaochen Chen,  Shengjun Ji,  Hui Yang,  Jiahao Zhu, 
  • First Published: 16 November 2020
Research Article
Open Access

Prostanoid Receptor Subtypes and Its Endogenous Ligands with Processing Enzymes within Various Types of Inflammatory Joint Diseases

Mohammed A. Al-Madol,  Mohammed Shaqura,  Thilo John,  Rudolf Likar,  Reham Said Ebied,  Magdi M. Salih,  Sascha Treskatsch,  Michael Schäfer,  Shaaban A. Mousa, 
  • First Published: 12 November 2020
Research Article
Open Access

Clinical Differences between Eosinophilic and Noneosinophilic Acute Exacerbation of Chronic Obstructive Pulmonary Disease: A Multicenter Cross-Sectional Study

Guangming Dai,  Yajuan Ran,  Jiajia Wang,  Xingru Chen,  Junnan Peng,  Xinglong Li,  Huojin Deng,  Min Xiao,  Tao Zhu, 
  • First Published: 12 November 2020
Research Article
Open Access

Culturing Articular Cartilage Explants in the Presence of Autologous Adipose Tissue Modifies Their Inflammatory Response to Lipopolysaccharide

Wendy Pearson,  Anna E. N. Garland,  Ashley Nixon,  John P. Cant,  Mark B. Hurtig, 
  • First Published: 12 November 2020
Research Article
Open Access

Baicalin Liposome Alleviates Lipopolysaccharide-Induced Acute Lung Injury in Mice via Inhibiting TLR4/JNK/ERK/NF-κB Pathway

Yu Long,  Yan Xiang,  Songyu Liu,  Yulu Zhang,  Jinyan Wan,  Qiyue Yang,  Mingquan Cui,  Zhimin Ci,  Nan Li,  Wei Peng, 
  • First Published: 11 November 2020
Research Article
Open Access

Effects of the Glutamine Administration on T Helper Cell Regulation and Inflammatory Response in Obese Mice Complicated with Polymicrobial Sepsis

Chiu-Li Yeh,  Li-Han Su,  Jin-Ming Wu,  Po-Jen Yang,  Po-Chu Lee,  Po-Da Chen,  Chun-Chieh Huang,  Der-Yirng Hsieh,  Hsueh-Ju Wang,  Sung-Ling Yeh,  Ming-Tsan Lin, 
  • First Published: 10 November 2020
Research Article
Open Access

Mibefradil and Flunarizine, Two T-Type Calcium Channel Inhibitors, Protect Mice against Lipopolysaccharide-Induced Acute Lung Injury

Limei Wan,  Weibin Wu,  Shunjun Jiang,  Shanhe Wan,  Dongmei Meng,  Zhipeng Wang,  Jiajie Zhang,  Li Wei,  Pengjiu Yu, 
  • First Published: 10 November 2020
Research Article
Open Access

Plasma Proteome Profiling of Coronary Artery Disease Patients: Downregulation of Transthyretin—An Important Event

Monu,  Rupsi Kharb,  Ankita Sharma,  Monu Kumar Chaddar,  Rakesh Yadav,  Prachi Agnihotri,  Anand Kar,  Sagarika Biswas, 
  • First Published: 10 November 2020
Research Article
Open Access

ASK1 Enhances Angiotensin II-Induced Liver Fibrosis In Vitro by Mediating Endoplasmic Reticulum Stress-Dependent Exosomes

Pei-pei Fang,  Chen-wei Pan,  Wei Lin,  Jie Li,  Shan-shan Huang,  Guang-yao Zhou,  Wen-jun Du,  Qiang Li, 
  • First Published: 09 November 2020
Corrigendum
Open Access

Corrigendum to “Interleukin-9 Deletion Relieves Vascular Dysfunction and Decreases Blood Pressure via the STAT3 Pathway in Angiotensin II-Treated Mice”

Yunzhao Yang,  Shaoqun Tang,  Chunchun Zhai,  Xin Zeng,  Qingjian Liu,  Cheng Xu,  Hexiang Chen, 
  • First Published: 09 November 2020

Research Article
Open Access

The Association of Fecal Microbiota in Ankylosing Spondylitis Cases with C-Reactive Protein and Erythrocyte Sedimentation Rate

Gang Liu,  Yonghong Hao,  Qiang Yang,  Shucai Deng, 
  • First Published: 07 November 2020
Research Article
Open Access

Negligible Effect of Estrogen Deficiency on Development of Skeletal Changes Induced by Type 1 Diabetes in Experimental Rat Models

Aleksandra Janas,  Ewa Kruczek,  Piotr Londzin,  Sławomir Borymski,  Zenon P. Czuba,  Joanna Folwarczna, 
  • First Published: 06 November 2020
Research Article
Open Access

Expression Profiling of Long Noncoding RNA and Messenger RNA in a Cecal Ligation and Puncture-Induced Colon Injury Mouse Model

Jinxiang Huang,  Yuan Liu,  Qingqiang Xie,  Guorui Liang,  Haifan Kong,  Meiling Liu,  Yujie Wang,  Shanshan Zhang,  Xuefeng Li, 
  • First Published: 04 November 2020
Retraction
Open Access

Retracted: Further Increase in the Expression of Activation Markers on Monocyte-Derived Dendritic Cells in Coronary Artery Disease Patients with Ectasia Compared to Patients with Coronary Artery Disease Alone

Mediators of Inflammation, 
  • First Published: 02 November 2020

Research Article
Open Access

Combinational Pretreatment of Colony-Stimulating Factor 1 Receptor Inhibitor and Triptolide Upregulates BDNF-Akt and Autophagic Pathways to Improve Cerebral Ischemia

Xiaoxue Du,  Feng Gao,  Shijia Chen,  Benson O. A. Botchway,  Nashwa Amin,  Zhiying Hu,  Marong Fang, 
  • First Published: 31 October 2020
Research Article
Open Access

Correlation between Blood and CSF Compartment Cytokines and Chemokines in Subjects with Cryptococcal Meningitis

Elizabeth C. Okafor,  Katherine H. Hullsiek,  Darlisha A. Williams,  James E. Scriven,  Joshua Rhein,  Henry W. Nabeta,  Abdu K. Musubire,  Radha Rajasingham,  Conrad Muzoora,  Charlotte Schutz,  Graeme Meintjes,  David B. Meya,  David R. Boulware, 
  • First Published: 29 October 2020
Research Article
Open Access

Increased Levels of Soluble CD206 Associated with Rapidly Progressive Interstitial Lung Disease in Patients with Dermatomyositis

Ya-Wen Shen,  Ya-Mei Zhang,  Zhen-Guo Huang,  Guo-Chun Wang,  Qing-Lin Peng, 
  • First Published: 28 October 2020
Review Article
Open Access

Review of the Roles and Interaction of Androgen and Inflammation in Benign Prostatic Hyperplasia

Yu Tong,  Ren-yuan Zhou, 
  • First Published: 28 October 2020
Research Article
Open Access

Involvement of the Inflammasome and Th17 Cells in Skin Lesions of Human Cutaneous Leishmaniasis Caused by Leishmania (Viannia) panamensis

K. Gonzalez,  J. E. Calzada,  C. E. P. Corbett,  A. Saldaña,  M. D. Laurenti, 
  • First Published: 28 October 2020
Research Article
Open Access

Isoorientin Inhibits Inflammation in Macrophages and Endotoxemia Mice by Regulating Glycogen Synthase Kinase 3β

Yingui Li,  Yijing Zhao,  Xiaoqin Tan,  Jiayan Liu,  Yingkun Zhi,  Lang Yi,  Shasha Bai,  Qun Du,  Qing X. Li,  Yan Dong, 
  • First Published: 28 October 2020
Research Article
Open Access

Short-Term Efficacy and Safety of Secukinumab for Ankylosing Spondylitis: A Systematic Review and Meta-Analysis of RCTs

Yu Zhou,  Jinhui Ma,  Juncheng Ge,  Bailiang Wang,  Debo Yue,  Weiguo Wang, 
  • First Published: 28 October 2020
Research Article
Open Access

Alterations in the Blood Parameters and Fecal Microbiota and Metabolites during Pregnant and Lactating Stages in Bama Mini Pigs as a Model

Cui Ma,  QianKun Gao,  WangHong Zhang,  Md. Abul Kalam Azad,  XiangFeng Kong, 
  • First Published: 26 October 2020
Research Article
Open Access

Serum and Cerebrospinal Fluid Cytokine Biomarkers for Diagnosis of Multiple Sclerosis

Ekaterina Martynova,  Mehendi Goyal,  Shikhar Johri,  Vinay Kumar,  Timur Khaibullin,  Albert A. Rizvanov,  Subhash Verma,  Svetlana F. Khaiboullina,  Manoj Baranwal, 
  • First Published: 26 October 2020
Research Article
Open Access

Expression of AIM2 in Rheumatoid Arthritis and Its Role on Fibroblast-Like Synoviocytes

Yong Chen,  Qiu Fujuan,  Ensheng Chen,  Beijia Yu,  Fangfang Zuo,  Yi Yuan,  Xiaofeng Zhao,  Changhong Xiao, 
  • First Published: 26 October 2020
Research Article
Open Access

Necrostatin-1 Synergizes the Pan Caspase Inhibitor to Attenuate Lung Injury Induced by Ischemia Reperfusion in Rats

Liangrong Wang,  Baihui Chen,  Xiangqing Xiong,  Shunli Chen,  Lida Jin,  Meizhen Zhu, 
  • First Published: 24 October 2020
Research Article
Open Access

Activating CD137 Signaling Promotes Sprouting Angiogenesis via Increased VEGFA Secretion and the VEGFR2/Akt/eNOS Pathway

Bo Li,  Yue Zhang,  Runting Yin,  Wei Zhong,  Rui Chen,  Jinchuan Yan, 
  • First Published: 24 October 2020
Research Article
Open Access

Association of Circulating Omentin-1 with Osteoporosis in a Chinese Type 2 Diabetic Population

Pijun Yan,  Yong Xu,  Zhihong Zhang,  Jianhua Zhu,  Ying Miao,  Chenlin Gao,  Qin Wan, 
  • First Published: 23 October 2020
Research Article
Open Access

Transforming Growth Factor Beta Receptor 3 Haplotypes in Sickle Cell Disease Are Associated with Lipid Profile and Clinical Manifestations

Rayra P. Santiago,  Camylla V. B. Figueiredo,  Luciana M. Fiuza,  Sètondji C. M. A. Yahouédéhou,  Rodrigo M. Oliveira,  Milena M. Aleluia,  Suellen P. Carvalho,  Cleverson A. Fonseca,  Valma M. L. Nascimento,  Larissa C. Rocha,  Caroline C. Guarda,  Marilda S. Gonçalves, 
  • First Published: 23 October 2020
Research Article
Open Access

Hypertryptasemia and Mast Cell-Related Disorders in Severe Osteoporotic Patients

Giulia Carosi,  Gregorio Guabello,  Matteo Longhi,  Federica Grifoni,  Elena Passeri,  Sabrina Corbetta, 
  • First Published: 22 October 2020
Research Article
Open Access

Characterization of Synovial Cytokine Patterns in Bucket-Handle and Posterior Horn Meniscal Tears

Marco Turati,  Davide Maggioni,  Nicolò Zanchi,  Marta Gandolla,  Massimo Gorla,  Paola Sacerdote,  Silvia Franchi,  Laura Rizzi,  Alessandra Pedrocchi,  Robert J. Omeljaniuk,  Giovanni Zatti,  Antonio Torsello,  Marco Bigoni, 
  • First Published: 22 October 2020
Research Article
Open Access

Molecularly Distinct NLRP3 Inducers Mediate Diverse Ratios of Interleukin-1β and Interleukin-18 from Human Monocytes

Kristine Midtbö,  Daniel Eklund,  Eva Särndahl,  Alexander Persson, 
  • First Published: 22 October 2020
Research Article
Open Access

Evaluating the Relationship of GDF-15 with Clinical Characteristics, Cardinal Features, and Survival in Multiple Myeloma

Małgorzata Banaszkiewicz,  Jolanta Małyszko,  Krzysztof Batko,  Ewa Koc-Żórawska,  Marcin Żórawski,  Paulina Dumnicka,  Artur Jurczyszyn,  Karolina Woziwodzka,  Joanna Tisończyk,  Marcin Krzanowski,  Jacek Małyszko,  Anna Waszczuk-Gajda,  Ryszard Drożdż,  Marek Kuźniewski,  Katarzyna Krzanowska, 
  • First Published: 21 October 2020
Research Article
Open Access

Crude Radix Aconiti Lateralis Preparata (Fuzi) with Glycyrrhiza Reduces Inflammation and Ventricular Remodeling in Mice through the TLR4/NF-κB Pathway

Ping Yan,  Wen Mao,  Lushuai Jin,  Mingsun Fang,  Xia Liu,  Jiali Lang,  Lu Jin,  Beibei Cao,  Qiyang Shou,  Huiying Fu, 
  • First Published: 20 October 2020
Corrigendum
Open Access

Corrigendum to “Loss of SNHG4 Attenuated Spinal Nerve Ligation-Triggered Neuropathic Pain through Sponging miR-423-5p”

Xia Pan,  Cheng Shen,  Yayi Huang,  Long Wang,  Zhongyuan Xia, 
  • First Published: 17 October 2020

Research Article
Open Access

Systemic Effects Induced by Hyperoxia in a Preclinical Model of Intra-abdominal Sepsis

M. Isabel García-Laorden,  Raquel Rodríguez-González,  José L. Martín-Barrasa,  Sonia García-Hernández,  Ángela Ramos-Nuez,  H. Celeste González-García,  Jesús M. González-Martín,  Robert M. Kacmarek,  Jesús Villar, 
  • First Published: 16 October 2020
Research Article
Open Access

Luteolin Attenuates IL-1β-Induced THP-1 Adhesion to ARPE-19 Cells via Suppression of NF-κB and MAPK Pathways

Wen-Chung Huang,  Chian-Jiun Liou,  Szu-Chuan Shen,  Sindy Hu,  Chien-Yu Hsiao,  Shu-Ju Wu, 
  • First Published: 16 October 2020
Research Article
Open Access

Saponin from Periploca forrestii Schltr Mitigates Oxazolone-Induced Atopic Dermatitis via Modulating Macrophage Activation

Luting Zeng,  Yingqin Liu,  Congcong Xing,  Yijie Huang,  Xin Sun,  Guangchen Sun, 
  • First Published: 15 October 2020
Research Article
Open Access

Real-Life Data on the Efficacy of Canakinumab in Patients with Adult-Onset Still’s Disease

Antonio Vitale,  Virginia Berlengiero,  Jurgen Sota,  Luisa Ciarcia,  Nicola Ricco,  Sara Barneschi,  Mariam Mourabi,  Giuseppe Lopalco,  Chiara Marzo,  Francesca Bellisai,  Florenzo Iannone,  Bruno Frediani,  Luca Cantarini, 
  • First Published: 15 October 2020
Research Article
Open Access

Simvastatin Posttreatment Controls Inflammation and Improves Bacterial Clearance in Experimental Sepsis

Flora Magno de Jesus Oliveira,  Cassiano Felippe Gonçalves-de-Albuquerque,  Isabel Matos Medeiros de Moraes,  Patrícia Alves Reis,  Vinicius Novaes Rocha,  Patrícia Torres Bozza,  Adriana Ribeiro Silva,  Hugo Caire de Castro Faria Neto, 
  • First Published: 14 October 2020
Research Article
Open Access

Guttiferone K Exerts the Anti-inflammatory Effect on Mycobacterium Tuberculosis- (H37Ra-) Infected Macrophages by Targeting the TLR/IRAK-1 Mediated Akt and NF-κB Pathway

Qingwen Zhang,  Jinxia Sun,  Yan Fu,  Weigang He,  Yinhong Li,  Hongsheng Tan,  Hongxi Xu,  Xin Jiang, 
  • First Published: 10 October 2020
Research Article
Open Access

Molecular Mechanisms of Glial Cells Related Signaling Pathways Involved in the Neuroinflammatory Response of Depression

Junhui Wang,  Jie Qin,  Peng Wang,  Yu Sun,  Qi Zhang, 
  • First Published: 10 October 2020
Research Article
Open Access

Mica Can Alleviate TNBS-Induced Colitis in Mice by Reducing Angiotensin II and IL-17A and Increasing Angiotensin-Converting Enzyme 2, Angiotensin 1-7, and IL-10

Mengdie Shen,  Bibi Zhang,  Mengyao Wang,  Li’na Meng,  Bin Lv, 
  • First Published: 10 October 2020
Research Article
Open Access

Chinese Medicine Huzhen Tongfeng Formula Effectively Attenuates Gouty Arthritis by Inhibiting Arachidonic Acid Metabolism and Inflammatory Mediators

Jianping Deng,  Zicong Wu,  Chen Chen,  Zhenling Zhao,  Yifei Li,  Zhengquan Su,  Yiguang Lin,  Yifei Wang,  Zhiping Wang, 
  • First Published: 09 October 2020
Research Article
Open Access

Identification of Potential Biomarkers and Immune Features of Sepsis Using Bioinformatics Analysis

Fang-Chen Gong,  Ran Ji,  Yu-Ming Wang,  Zhi-Tao Yang,  Ying Chen,  En-Qiang Mao,  Er-Zhen Chen, 
  • First Published: 09 October 2020
Research Article
Open Access

CD4+ T Cell Profile and Activation Response in Sickle Cell Disease Patients with Osteonecrosis

Paula B. Daltro,  Tiago O. Ribeiro,  Gildásio C. Daltro,  Roberto J. Meyer,  Vitor Fortuna, 
  • First Published: 09 October 2020
Research Article
Open Access

Serum Cystatin C and Coronavirus Disease 2019: A Potential Inflammatory Biomarker in Predicting Critical Illness and Mortality for Adult Patients

Dan Chen,  Wenwu Sun,  Jia Li,  Bohua Wei,  Wei Liu,  Xiaopin Wang,  Fan Song,  Liangkai Chen,  Junhui Yang,  Li Yu, 
  • First Published: 08 October 2020
Research Article
Open Access

Inhibitory Effects of Apigenin on Tumor Carcinogenesis by Altering the Gut Microbiota

Shichang Bian,  Hongjuan Wan,  Xinyan Liao,  Weisheng Wang, 
  • First Published: 06 October 2020
Research Article
Open Access

Essential Oil and Juice from Bergamot and Sweet Orange Improve Acne Vulgaris Caused by Excessive Androgen Secretion

Peng Sun,  Liang Zhao,  Nanhai Zhang,  Chengtao Wang,  Wei Wu,  Arshad Mehmood,  Liebing Zhang,  Baoping Ji,  Feng Zhou, 
  • First Published: 06 October 2020
Review Article
Open Access

The Role of Matrix Metalloproteinase-9 in Atherosclerotic Plaque Instability

Tiewei Li,  Xiaojuan Li,  Yichuan Feng,  Geng Dong,  Yuewu Wang,  Junmei Yang, 
  • First Published: 06 October 2020
Research Article
Open Access

Disease-Specific Autoantibodies Induce Trained Immunity in RA Synovial Tissues and Its Gene Signature Correlates with the Response to Clinical Therapy

Xiaoli Dai,  Xiaoqiu Dai,  Zheng Gong,  Chen Yang,  Keqin Zeng,  Fang-Yuan Gong,  Qiao Zhong,  Xiao-Ming Gao, 
  • First Published: 06 October 2020
Research Article
Open Access

Baicalein Restores the Balance of Th17/Treg Cells via Aryl Hydrocarbon Receptor to Attenuate Colitis

Chang Liu,  Yanyang Li,  Yanping Chen,  Shaowei Huang,  Xiaojing Wang,  Shuang Luo,  Yulin Su,  Lian Zhou,  Xia Luo, 
  • First Published: 05 October 2020
Review Article
Open Access

The Role of Inflammation in the Pathogenesis of Preeclampsia

Michał Michalczyk,  Aleksander Celewicz,  Marta Celewicz,  Paula Woźniakowska-Gondek,  Rafał Rzepka, 
  • First Published: 05 October 2020
Research Article
Open Access

Trained Innate Immunity by Repeated Low-Dose Lipopolysaccharide Injections Displays Long-Term Neuroprotective Effects

Xiao-yan Zhou,  Rong Gao,  Jian Hu,  Da-peng Gao,  Yan-ling Liao,  Jian-jun Yang, 
  • First Published: 01 October 2020
Research Article
Open Access

P2Y2 Receptor Induces L. amazonensis Infection Control in a Mechanism Dependent on Caspase-1 Activation and IL-1β Secretion

Maria Luiza Thorstenberg,  Monique Daiane Andrade Martins,  Vanessa Figliuolo,  Claudia Lucia Martins Silva,  Luiz Eduardo Baggio Savio,  Robson Coutinho-Silva, 
  • First Published: 01 October 2020
Research Article
Open Access

The Expression Pattern and Regulatory Mechanism of the G0/G1 Switch Gene 2 (G0S2) in the Pathogenesis and Treatment of AChR Myasthenia Gravis (MG)

Liqun Xu,  Zhibin Li,  Yi Li,  Zhaohui Luo,  Yuebei Luo,  Bo Xiao,  Huan Yang, 
  • First Published: 30 September 2020
Clinical Study
Open Access

Elevated Circulating Fetuin-B Levels Are Associated with Insulin Resistance and Reduced by GLP-1RA in Newly Diagnosed PCOS Women

Mani Mokou,  Shan Yang,  Bin Zhan,  Shan Geng,  Kejia Li,  Mengliu Yang,  Gangyi Yang,  Wuquan Deng,  Hua Liu,  Dongfang Liu,  Zhiming Zhu,  Ling Li, 
  • First Published: 30 September 2020
Retraction
Open Access

Retracted: The Anti-Inflammatory Effects of Shinbaro3 Is Mediated by Downregulation of the TLR4 Signalling Pathway in LPS-Stimulated RAW 264.7 Macrophages

Mediators of Inflammation, 
  • First Published: 29 September 2020

Research Article
Open Access

Distinguishable Immunologic Characteristics of COVID-19 Patients with Comorbid Type 2 Diabetes Compared with Nondiabetic Individuals

Ruxing Zhao,  Yujing Sun,  Yongyuan Zhang,  Weili Wang,  Shouyu Wang,  Chuang Wang,  Jinbo Liu,  Ling Gao,  Zhao Hu,  Jianchun Fei,  Xinguo Hou,  Huizhen Zheng,  Li Chen, 
  • First Published: 29 September 2020
Research Article
Open Access

Anticolitic Effect of Berberine in Rat Experimental Model: Impact of PGE2/p38 MAPK Pathways

Li Jia,  Kuijin Xue,  Junheng Liu,  Ola A. Habotta,  Lianhai Hu,  Ahmed E. Abdel Moneim, 
  • First Published: 29 September 2020
Research Article
Open Access

Exploring the Mechanism on the Medullary Visceral Zone Inhibiting the Cholinergic Anti-inflammatory Pathway Induced by Sepsis

H. B. Li,  Y. Zhou,  A. H. Zhao,  L. L. Guo, 
  • First Published: 29 September 2020
Research Article
Open Access

Serum Soluble Interleukin-2 Receptor Does Not Differentiate Complex Regional Pain Syndrome from Other Pain Conditions in a Tertiary Referral Setting

K. D. Bharwani,  M. Dirckx,  D. L. Stronks,  W. A. Dik,  F. J. P. M. Huygen, 
  • First Published: 28 September 2020
Clinical Study
Open Access

The Role of Multimodality Imaging in Monitoring Disease Activity and Therapeutic Response to Tocilizumab in Giant Cell Arteritis

Edoardo Conticini,  Jurgen Sota,  Paolo Falsetti,  Caterina Baldi,  Marco Bardelli,  Francesca Bellisai,  Gian Marco Tosi,  Bruno Frediani,  Luca Cantarini, 
  • First Published: 27 September 2020
Research Article
Open Access

Serum YKL-40 Levels Are Associated with the Atherogenic Index of Plasma in Children

Yoowon Kwon,  Ju Hee Kim,  Eun Kyo Ha,  Hye Mi Jee,  Hey Sung Baek,  Man Yong Han,  Su Jin Jeong, 
  • First Published: 26 September 2020
Research Article
Open Access

Evaluation of the Biomarkers HMGB1 and IL-6 as Predictors of Mortality in Cirrhotic Patients with Acute Kidney Injury

Célio Geraldo de Oliveira Gomes,  Marcus Vinicius Melo de Andrade,  Ludmila Resende Guedes,  Henrique Carvalho Rocha,  Roberto Gardone Guimarães,  Fernando Antônio Castro Carvalho,  Eduardo Garcia Vilela, 
  • First Published: 25 September 2020
Research Article
Open Access

Diagnostic and Predictive Values of Inflammatory Factors in Pathology and Survival of Patients Undergoing Total Cystectomy

Xingxing Tang,  Yudong Cao,  Jia Liu,  Shuo Wang,  Yong Yang,  Peng Du, 
  • First Published: 24 September 2020
Research Article
Open Access

Metabolic Profiling by UPLC–Orbitrap–MS/MS of Liver from C57BL/6 Mice with DSS-Induced Inflammatory Bowel Disease

Zhongquan Xin,  Zhenya Zhai,  Hongrong Long,  Fan Zhang,  Xiaojun Ni,  Jinping Deng,  Lunzhao Yi,  Baichuan Deng, 
  • First Published: 23 September 2020
Review Article
Open Access

Cytokine Storm in COVID-19 Patients, Its Impact on Organs and Potential Treatment by QTY Code-Designed Detergent-Free Chemokine Receptors

Mujahed I. Mustafa,  Abdelrahman H. Abdelmoneim,  Eiman M. Mahmoud,  Abdelrafie M. Makhawi, 
  • First Published: 23 September 2020
Research Article
Open Access

Effects of Altered Levels of Pro- and Anti-Inflammatory Mediators on Locations of In-Stent Reocclusions in Elderly Patients

Xia Li,  Dianxuan Guo,  Ying Chen,  Youdong Hu,  Fenglin Zhang, 
  • First Published: 23 September 2020
Retraction
Open Access

Retracted: Neuropilin-1highCD4+CD25+ Regulatory T Cells Exhibit Primary Negative Immunoregulation in Sepsis

Mediators of Inflammation, 
  • First Published: 18 September 2020

Research Article
Open Access

TLR4/AP-1-Targeted Anti-Inflammatory Intervention Attenuates Insulin Sensitivity and Liver Steatosis

Xiang Hu,  Jing Zhou,  Sha-sha Song,  Wen Kong,  Yan-Chuan Shi,  Lu-Lu Chen,  Tian-Shu Zeng, 
  • First Published: 16 September 2020
Research Article
Open Access

Increased Serum Interleukin-2 Levels Are Associated with Abnormal Peripheral Blood Natural Killer Cell Levels in Patients with Active Rheumatoid Arthritis

Baochen Li,  Qiaoling Guo,  Yanyan Wang,  Rui Su,  Chong Gao,  Jinfang Zhao,  Xiaofeng Li,  Caihong Wang, 
  • First Published: 15 September 2020
Research Article
Open Access

Circulating Th1 and Th2 Subset Accumulation Kinetics in Septic Patients with Distinct Infection Sites: Pulmonary versus Nonpulmonary

Ming Xue,  Yuying Tang,  Xu Liu,  Mingyuan Gu,  Jianfeng Xie,  Ling Liu,  Yingzi Huang,  Fengmei Guo,  Yi Yang,  Haibo Qiu, 
  • First Published: 14 September 2020
Review Article
Open Access

Pain Mechanism in Rheumatoid Arthritis: From Cytokines to Central Sensitization

Yanting Cao,  Danping Fan,  Yiqing Yin, 
  • First Published: 12 September 2020
Corrigendum
Open Access

Corrigendum to “CD206+ Cell Number Differentiates Influenza A (H1N1)pdm09 from Seasonal Influenza A Virus in Fatal Cases”

Heidi G. Rodriguez-Ramirez,  Mario C. Salinas-Carmona,  Oralia Barboza-Quintana,  Americo Melo-de la Garza,  Luis Angel Ceceñas-Falcon,  Lilia M. Rangel-Martinez,  Adrian G. Rosas-Taraco, 
  • First Published: 11 September 2020

Research Article
Open Access

IκB Kinase Inhibitor VII Modulates Sepsis-Induced Excessive Inflammation and Cardiac Dysfunction in 5/6 Nephrectomized Mice

Mei Ding,  Dede Lian,  Lirong Zhang,  Tiechao Jiang,  Wei Wang, 
  • First Published: 10 September 2020

Research Article
Open Access

Expression of Matrix Metalloproteinases and Their Tissue Inhibitors in Peripheral Blood Leukocytes and Plasma of Children with Nonalcoholic Fatty Liver Disease

Joanna B. Trojanek,  Jacek Michałkiewicz,  Renata Grzywa-Czuba,  Wojciech Jańczyk,  Lidia Gackowska,  Izabela Kubiszewska,  Anna Helmin-Basa,  Aldona Wierzbicka-Rucińska,  Mieczysław Szalecki,  Piotr Socha, 
  • First Published: 10 September 2020
Review Article
Open Access

The Potential of Food Protein-Derived Bioactive Peptides against Chronic Intestinal Inflammation

Wanying Zhu,  Liying Ren,  Li Zhang,  Qinqin Qiao,  Muhammad Zahid Farooq,  Qingbiao Xu, 
  • First Published: 09 September 2020
Research Article
Open Access

Leptin Promoted IL-17 Production from ILC2s in Allergic Rhinitis

Yanhui Wen,  Qingxiang Zeng,  Xi Luo,  Renqiang Ma,  Yiquan Tang,  Wenlong Liu, 
  • First Published: 09 September 2020
Review Article
Open Access

Interactions between Gut Microbiota and Immunomodulatory Cells in Rheumatoid Arthritis

Huihui Xu,  Hongyan Zhao,  Danping Fan,  Meijie Liu,  Jinfeng Cao,  Ya Xia,  Dahong Ju,  Cheng Xiao,  Qingdong Guan, 
  • First Published: 09 September 2020
Research Article
Open Access

Overexpression of Ubiquitin-Specific Protease 2 (USP2) in the Heart Suppressed Pressure Overload-Induced Cardiac Remodeling

Junhui Xing,  Pengcheng Li,  Jin Hong,  Mengyu Wang,  Yuzhou Liu,  Yueqiao Gao,  Jianzeng Dong,  Heping Gu,  Ling Li, 
  • First Published: 07 September 2020
Retraction
Open Access

Retracted: The Parenteral Vitamin C Improves Sepsis and Sepsis-Induced Multiple Organ Dysfunction Syndrome via Preventing Cellular Immunosuppression

Mediators of Inflammation, 
  • First Published: 04 September 2020

Research Article
Open Access

Neutrophil-Lymphocyte Ratio (NLR) Reflects Myocardial Inhomogeneities in Hemodialyzed Patients

Kamila Bołtuć,  Arkadiusz Bociek,  Robert Dziugieł,  Martyna Bociek,  Tomasz Zapolski,  Wojciech Dąbrowski,  Andrzej Jaroszyński, 
  • First Published: 03 September 2020
Research Article
Open Access

Lower Central Fat Increase Risk of One-Year Muscle Mass Loss in Menopausal Women

Ying-Chou Chen,  Wei-Che Lin,  Tien-Tsai Cheng,  Jia-Feng Chen,  Shan-Fu Yu,  Chung-Yuan Hsu, 
  • First Published: 02 September 2020
Review Article
Open Access

The Central Role and Possible Mechanisms of Bacterial DNAs in Sepsis Development

Zhenxing Cheng,  Simon T. Abrams,  James Austin,  Julien Toh,  Susan Siyu Wang,  Zhi Wang,  Qian Yu,  Weiping Yu,  Cheng Hock Toh,  Guozheng Wang, 
  • First Published: 31 August 2020
Research Article
Open Access

Fatty Acid Profile and Metabolism Are Related to Human Sperm Parameters and Are Relevant in Idiopathic Infertility and Varicocele

Giulia Collodel,  Elena Moretti,  Daria Noto,  Francesca Iacoponi,  Cinzia Signorini, 
  • First Published: 31 August 2020
Research Article
Open Access

CypB-CD147 Signaling Is Involved in Crosstalk between Cartilage and FLS in Collagen-Induced Arthritis

Qishan Wang,  Bingxin Xu,  Kaijian Fan,  Jing Wu,  Tingyu Wang, 
  • First Published: 29 August 2020
Research Article
Open Access

MicroRNA-155 Participates in the Expression of LSD1 and Proinflammatory Cytokines in Rheumatoid Synovial Cells

Ziliang Yu,  Hao Liu,  Jianbo Fan,  Feihu Chen,  Wei Liu, 
  • First Published: 27 August 2020
Corrigendum
Open Access

Corrigendum to “miR-221 Alleviates the Ox-LDL-Induced Macrophage Inflammatory Response via the Inhibition of DNMT3b-Mediated NCoR Promoter Methylation”

Jinshan Ye,  Yaxi Wu,  Ruiwei Guo,  Wenjun Zeng,  Yanan Duan,  Zhihua Yang,  Lixia Yang, 
  • First Published: 21 August 2020

Research Article
Open Access

The Predictive Value of Growth Differentiation Factor-15 in Recurrence of Atrial Fibrillation after Catheter Ablation

Ying Wei,  Shuwang Liu,  Haiyi Yu,  Yuan Zhang,  Wei Gao,  Ming Cui,  Lei Li, 
  • First Published: 21 August 2020
Research Article
Open Access

The Role of T Cells and Macrophages in Asthma Pathogenesis: A New Perspective on Mutual Crosstalk

Xueyi Zhu,  Jie Cui,  La Yi,  Jingjing Qin,  Wuniqiemu Tulake,  Fangzhou Teng,  Weifeng Tang,  Ying Wei,  Jingcheng Dong, 
  • First Published: 19 August 2020
Review Article
Open Access

The Functional Roles of IL-33/ST2 Axis in Ocular Diseases

Yujing Qian,  Meifen Zhang, 
  • First Published: 18 August 2020
Review Article
Open Access

The Association between Inflammation and Pulse Wave Velocity in Dyslipidemia: An Evidence-Based Review

Amilia Aminuddin,  Md Rizman M. L. M. Lazim,  Adila A. Hamid,  Chua K. Hui,  Mohd H. Mohd Yunus,  Jaya Kumar,  Azizah Ugusman, 
  • First Published: 18 August 2020
Research Article
Open Access

Ac2-26 Alleviates Brain Injury after Cardiac Arrest and Cardiopulmonary Resuscitation in Rats via the eNOS Pathway

Jing Gong,  Qi-Hang Tai,  Guang-Xiao Xu,  Xue-Ting Wang,  Jing-Li Zhu,  Xiao-Qing Zhao,  Hai-Bin Sun,  Dan Zhu,  Wei Gao, 
  • First Published: 18 August 2020
Research Article
Open Access

Circulating Inflammatory Markers Are Inversely Associated with Heart Rate Variability Measures in Type 1 Diabetes

Anne-Marie L. Wegeberg,  Tina Okdahl,  Tina Fløyel,  Christina Brock,  Niels Ejskjaer,  Sam Riahi,  Flemming Pociot,  Joachim Størling,  Birgitte Brock, 
  • First Published: 18 August 2020
Research Article
Open Access

miRNA-10a-5p Alleviates Insulin Resistance and Maintains Diurnal Patterns of Triglycerides and Gut Microbiota in High-Fat Diet-Fed Mice

Yawei Guo,  Xiaohui Zhu,  Sha Zeng,  Mingyi He,  Xiurong Xing,  Changyuan Wang, 
  • First Published: 17 August 2020
Research Article
Open Access

Micheliolide Attenuates Lipopolysaccharide-Induced Inflammation by Modulating the mROS/NF-κB/NLRP3 Axis in Renal Tubular Epithelial Cells

Xianghong Lei,  Shuting Li,  Congwei Luo,  Yuxian Wang,  Yanxia Liu,  Zhaozhong Xu,  Qianyin Huang,  Fangqin Zou,  Yihua Chen,  Fenfen Peng,  Haibo Long, 
  • First Published: 17 August 2020
Review Article
Open Access

The Role of CTHRC1 in Regulation of Multiple Signaling and Tumor Progression and Metastasis

Dan Mei,  Yue Zhu,  Lingling Zhang,  Wei Wei, 
  • First Published: 12 August 2020
Review Article
Open Access

Role of RING-Type E3 Ubiquitin Ligases in Inflammatory Signalling and Inflammatory Bowel Disease

Liguo Zhu,  Ying Li,  Longyuan Zhou,  Guang Yang,  Ying Wang,  Jing Han,  Li Li,  Shenghong Zhang, 
  • First Published: 10 August 2020
Research Article
Open Access

Anti-Inflammatory and Antioxidant Effects of Carpesium cernuum L. Methanolic Extract in LPS-Stimulated RAW 264.7 Macrophages

Yea-Jin Park,  Se-Yun Cheon,  Dong-Sung Lee,  Divina C. Cominguez,  Zhiyun Zhang,  Sangwoo Lee,  Hyo-Jin An, 
  • First Published: 08 August 2020
Research Article
Open Access

Midregional Proadrenomedullin (MRproADM) Serum Levels in Critically Ill Patients Are Associated with Short-Term and Overall Mortality during a Two-Year Follow-Up

Lukas Buendgens,  Eray Yagmur,  Axel Ginsberg,  Ralf Weiskirchen,  Theresa Wirtz,  Samira Abu Jhaisha,  Albrecht Eisert,  Tom Luedde,  Christian Trautwein,  Frank Tacke,  Alexander Koch, 
  • First Published: 07 August 2020
Research Article
Open Access

Advanced Glycation End Products Induce Vascular Smooth Muscle Cell-Derived Foam Cell Formation and Transdifferentiate to a Macrophage-Like State

Zhengyang Bao,  Lihua Li,  Yue Geng,  Jinchuan Yan,  Zhiyin Dai,  Chen Shao,  Zhen Sun,  Lele Jing,  Qiwen Pang,  Lili Zhang,  Xiaodong Wang,  Zhongqun Wang, 
  • First Published: 07 August 2020
Research Article
Open Access

Clinical Features at Onset and Genetic Characterization of Pediatric and Adult Patients with TNF-α Receptor—Associated Periodic Syndrome (TRAPS): A Series of 80 Cases from the AIDA Network

Carla Gaggiano,  Antonio Vitale,  Laura Obici,  Giampaolo Merlini,  Alessandra Soriano,  Ombretta Viapiana,  Marco Cattalini,  Maria Cristina Maggio,  Giuseppe Lopalco,  Davide Montin,  Masen Abdel Jaber,  Lorenzo Dagna,  Raffaele Manna,  Antonella Insalaco,  Matteo Piga,  Francesco La Torre,  Virginia Berlengiero,  Viviana Gelardi,  Luisa Ciarcia,  Giacomo Emmi,  Piero Ruscitti,  Francesco Caso,  Rolando Cimaz,  José Hernández-Rodríguez,  Paola Parronchi,  Ludovico Luca Sicignano,  Elena Verrecchia,  Florenzo Iannone,  Jurgen Sota,  Salvatore Grosso,  Carlo Salvarani,  Bruno Frediani,  Roberto Giacomelli,  Maria Antonietta Mencarelli,  Alessandra Renieri,  Donato Rigante,  Luca Cantarini, 
  • First Published: 07 August 2020
Research Article
Open Access

The Effects of Dietary Glycine on the Acetic Acid-Induced Mouse Model of Colitis

Xin Wu,  Yongmin Zheng,  Jie Ma,  Jie Yin,  Shuai Chen, 
  • First Published: 05 August 2020
Research Article
Open Access

Association of C1q/TNF-Related Protein-9 (CTRP9) Level with Obstructive Sleep Apnea in Patients with Coronary Artery Disease

Zexuan Li,  Yunhui Du,  Lixin Jia,  Jingyao Fan,  Ruifeng Guo,  Xinliang Ma,  Xiao Wang,  Shaoping Nie,  Yongxiang Wei, 
  • First Published: 05 August 2020
Research Article
Open Access

Protection of Fecal Microbiota Transplantation in a Mouse Model of Multiple Sclerosis

Kanglan Li,  Shouchao Wei,  Li Hu,  Xiaojian Yin,  Yingren Mai,  Chunmei Jiang,  Xiaoping Peng,  Xingxing Cao,  Zhongkai Huang,  Haihong Zhou,  Guoda Ma,  Zhou Liu,  Huiliang Li,  Bin Zhao, 
  • First Published: 05 August 2020
Research Article
Open Access

Higher Serum Neuropeptide Y Levels Are Associated with Metabolically Unhealthy Obesity in Obese Chinese Adults: A Cross-Sectional Study

Hao-Neng Tang,  Fen Xiao,  Ya-Ru Chen,  Si-Qi Zhuang,  Yue Guo,  Hui-Xuan Wu,  Hou-De Zhou, 
  • First Published: 04 August 2020
Research Article
Open Access

Inhibition of the ROS-EGFR Pathway Mediates the Protective Action of Nox1/4 Inhibitor GKT137831 against Hypertensive Cardiac Hypertrophy via Suppressing Cardiac Inflammation and Activation of Akt and ERK1/2

Si-yu Zeng,  Qiu-jiang Yan,  Li Yang,  Qing-hua Mei,  Hui-qin Lu, 
  • First Published: 04 August 2020
Research Article
Open Access

Comprehensive Analysis of a circRNA-miRNA-mRNA Network to Reveal Potential Inflammation-Related Targets for Gastric Adenocarcinoma

YunXia Liu,  YeFeng Xu,  Feng Xiao,  JianFeng Zhang,  YiQing Wang,  YongWei Yao,  JieWen Yang, 
  • First Published: 01 August 2020
Research Article
Open Access

Plasma and Cellular Forms of Fibronectin as Prognostic Markers in Sepsis

Anna Lemańska-Perek,  Dorota Krzyżanowska-Gołąb,  Tomasz Skalec,  Barbara Adamik, 
  • First Published: 01 August 2020
Research Article
Open Access

Mast Cell Deficiency Protects Mice from Surgery-Induced Neuroinflammation

Xiang Zhang,  Hongquan Dong,  Fei Wang,  Jun Zhang, 
  • First Published: 01 August 2020
Research Article
Open Access

Aplysin Retards Pancreatic Necrosis and Inflammatory Responses in NOD Mice by Stabilizing Intestinal Barriers and Regulating Gut Microbial Composition

Ying Liu,  Xinyue Cui,  Ming-Qing Gao,  Meilan Xue,  Hongwei Xu,  Zhishang Chang,  Yushan Jiang,  Hui Liang, 
  • First Published: 01 August 2020
Research Article
Open Access

Association of Pathogenic Th17 Cells with the Disease Severity and Its Potential Implication for Biological Treatment Selection in Psoriasis Patients

Cristina Aguilar-Flores,  Octavio Castro-Escamilla,  Elizabeth M. Ortega-Rocha,  César Maldonado-García,  Fermín Jurado-Santa Cruz,  Gibrán Pérez-Montesinos,  Alicia Lemini-López,  Laura C. Bonifaz, 
  • First Published: 31 July 2020
Research Article
Open Access

Imbalance in PB IL-17-Secreting and Regulatory Cells in Pars Planitis Is Associated with Dysregulation of IFN-γ-Secreting Cells, Especially in Patients with Clinical Complications

Agata Kosmaczewska,  Joanna Przeździecka-Dołyk,  Anna Turno-Kręcicka,  Lidia Ciszak,  Aleksandra Szteblich,  Agnieszka Węgrzyn,  Irena Frydecka,  Marta Misiuk-Hojło, 
  • First Published: 31 July 2020
Research Article
Open Access

Role of Oxygen Supply in Macrophages in a Model of Simulated Orthodontic Tooth Movement

Agnes Schröder,  Leonie Barschkies,  Jonathan Jantsch,  Peter Proff,  Lina Gölz,  James Deschner,  Christian Kirschneck, 
  • First Published: 29 July 2020
Review Article
Open Access

Significance of Omega-3 Fatty Acids in the Prophylaxis and Treatment after Spinal Cord Injury in Rodent Models

Piotr Wojdasiewicz,  Łukasz A. Poniatowski,  Paweł Turczyn,  Justyna Frasuńska,  Agnieszka Paradowska-Gorycka,  Beata Tarnacka, 
  • First Published: 29 July 2020
Research Article
Open Access

Soluble IL-2 Receptor in Dermatomyositis: Its Associations with Skin Ulcers and Disease Activity

Linrong He,  Xiaoming Shu,  Xia Liu,  Yongpeng Ge,  Sizhao Li,  Xin Lu,  Guochun Wang, 
  • First Published: 28 July 2020
Review Article
Open Access

Neutrophil Extracellular Traps: Signaling Properties and Disease Relevance

Tiewei Li,  Zhengyan Zhang,  Xiaojuan Li,  Geng Dong,  Min Zhang,  Zhe Xu,  Junmei Yang, 
  • First Published: 28 July 2020
Research Article
Open Access

The Influence of Adalimumab and Cyclosporine A on the Expression Profile of the Genes Related to TGFβ Signaling Pathways in Keratinocyte Cells Treated with Lipopolysaccharide A

Iwona Adwent,  Beniamin Oskar Grabarek,  Marta Kojs-Mrożkiewicz,  Ryszard Brus,  Rafał Staszkiewicz,  Andrzej Plewka,  Michał Stasiowski,  Anita Lyssek-Boroń, 
  • First Published: 26 July 2020
Research Article
Open Access

The Depletion of ABI3BP by MicroRNA-183 Promotes the Development of Esophageal Carcinoma

Hongfei Cai,  Yang Li,  Da Qin,  Rui Wang,  Ze Tang,  Tianyu Lu,  Youbin Cui, 
  • First Published: 26 July 2020
Review Article
Open Access

Understanding the Role of Exercise in Nonalcoholic Fatty Liver Disease: ERS-Linked Molecular Pathways

Yong Zou,  Zhengtang Qi, 
  • First Published: 25 July 2020
Research Article
Open Access

PDK1/mTOR Signaling in Myeloid Cells Differentially Regulates the Early and Late Stages of Sepsis

Juan Du,  Guoli Li,  Mingxi Hua,  Junyan Han,  Yu Hao,  Hui Zeng,  Ang Li,  Yaxian Kong, 
  • First Published: 25 July 2020
Review Article
Open Access

Research Progress on NK Cell Receptors and Their Signaling Pathways

Yingying Chen,  Dan Lu,  Alexey Churov,  Rong Fu, 
  • First Published: 24 July 2020
Research Article
Open Access

Cyr61 Promotes Inflammation of a Gouty Arthritis Model in Rats

Mi Zhou,  Kan Ze,  Liang Hua,  Liu Liu,  Le Kuai,  Ming Zhang,  Bin Li,  Yifei Wang,  Xin Li, 
  • First Published: 24 July 2020
Research Article
Open Access

Overexpression of CXCL14 Alleviates Ventilator-Induced Lung Injury through the Downregulation of PKM2-Mediated Cytokine Production

Rui Zhu,  Yan-Qing Lei,  Dong-Chi Zhao, 
  • First Published: 23 July 2020
Research Article
Open Access

High T3 Induces β-Cell Insulin Resistance via Endoplasmic Reticulum Stress

Bo Liang,  Liyun Liu,  Huibin Huang,  Liangyi Li,  Jingxiong Zhou, 
  • First Published: 22 July 2020
Research Article
Open Access

Inhibition of miR-17~92 Cluster Ameliorates High Glucose-Induced Podocyte Damage

Xiaobao Fan,  Zhiming Hao,  Zhenjiang Li,  Xiaoming Wang,  Jing Wang, 
  • First Published: 21 July 2020
Corrigendum
Open Access

Corrigendum to “Dietary Magnesium Intake and Leukocyte Telomere Attrition in Adults: The Regulatory Role of Serum Tumor Necrosis Factor α”

Jie Yu,  Haibin Liu,  Shuli He,  Pingping Li,  Chunxiao Ma,  Minglei Ma,  Yiwen Liu,  Lu Lv,  Fan Ping,  Huabing Zhang,  Wei Li,  Qi Sun,  Lingling Xu,  Yuxiu Li, 
  • First Published: 18 July 2020

Review Article
Open Access

Neutrophil Extracellular Traps (NETs) and Damage-Associated Molecular Patterns (DAMPs): Two Potential Targets for COVID-19 Treatment

Sebastiano Cicco,  Gerolamo Cicco,  Vito Racanelli,  Angelo Vacca, 
  • First Published: 16 July 2020
Research Article
Open Access

Serum Cholinesterases, a Novel Marker of Clinical Activity in Inflammatory Bowel Disease: A Retrospective Case-Control Study

Xiaona Shao,  Lei Yang,  Keyue Hu,  Ruiwei Shen,  Qunqun Ye,  Xiaogang Yuan,  Qiang Zhao,  Jianwei Shen, 
  • First Published: 14 July 2020
Research Article
Open Access

Relationship of Serum Levels of IL-17, IL-18, TNF-α, and Lung Function Parameters in Patients with COPD, Asthma-COPD Overlap, and Bronchial Asthma

Nailya Kubysheva,  Marina Boldina,  Tatyana Eliseeva,  Svetlana Soodaeva,  Igor Klimanov,  Anastasia Khaletskaya,  Venera Bayrasheva,  Valery Solovyev,  Luis Alfonso Villa-Vargas,  Marco Antonio Ramírez-Salinas,  Moisés Salinas-Rosales,  Dmitry Yu. Ovsyannikov,  Ildar Batyrshin, 
  • First Published: 12 July 2020
Research Article
Open Access

IL-37 Exerts Anti-Inflammatory Effects in Fetal Membranes of Spontaneous Preterm Birth via the NF-κB and IL-6/STAT3 Signaling Pathway

Lulu Wang,  Zheng Liu,  Dongni Huang,  Yuxin Ran,  Hanwen Zhang,  Jie He,  Nanlin Yin,  Hongbo Qi, 
  • First Published: 11 July 2020
Research Article
Open Access

A Novel Putative Role of TNK1 in Atherosclerotic Inflammation Implicating the Tyk2/STAT1 Pathway

Mei-Hua Bao,  Qiao-Li Lv,  Hai-Gang Li,  Yi-Wen Zhang,  Bao-Feng Xu,  Bin-Sheng He, 
  • First Published: 10 July 2020
Research Article
Open Access

Evaluation of IL-29 in Euthyroid Patients with Graves’ Orbitopathy: A Preliminary Study

Bogusz Falkowski,  Ewelina Szczepanek-Parulska,  Nadia Sawicka-Gutaj,  Aleksandra Krygier,  Marek Ruchala, 
  • First Published: 09 July 2020
Research Article
Open Access

Association of Lifestyle and Body Composition on Risk Factors of Cardiometabolic Diseases and Biomarkers in Female Adolescents

Valter Paulo Neves Miranda,  Paulo Roberto dos Santos Amorim,  Ronaldo Rocha Bastos,  Karina Lúcia Ribeiro Canabrava,  Márcio Vidigal Miranda Júnior,  Fernanda Rocha Faria,  Sylvia do Carmo Castro Franceschini,  Maria do Carmo Gouveia Peluzio,  Silvia Eloiza Priore, 
  • First Published: 09 July 2020
Research Article
Open Access

Intraoperative Peritoneal Interleukin-6 Concentration Changes in Relation to the High-Mobility Group Protein B1 and Heat Shock Protein 70 Levels in Children Undergoing Cholecystectomy

Marzena Tylicka,  Ewa Matuszczak,  Joanna Kamińska,  Wojciech Dębek,  Beata Modzelewska,  Tomasz Kleszczewski,  Violetta Dymicka-Piekarska,  Joanna Matowicka-Karna,  Maria Karpińska,  Olga M. Koper-Lenkiewicz, 
  • First Published: 08 July 2020
Review Article
Open Access

Molecular Mechanisms Contributing Bacterial Infections to the Incidence of Various Types of Cancer

Salah A. Sheweita,  Awad S. Alsamghan, 
  • First Published: 08 July 2020
Research Article
Open Access

Biological Characterization of Commercial Recombinantly Expressed Immunomodulating Proteins Contaminated with Bacterial Products in the Year 2020: The SAA3 Case

Sara Abouelasrar Salama,  Mirre De Bondt,  Nele Berghmans,  Mieke Gouwy,  Vivian Louise Soares de Oliveira,  Sergio C. Oliveira,  Flavio A. Amaral,  Paul Proost,  Jo Van Damme,  Sofie Struyf,  Mieke De Buck, 
  • First Published: 06 July 2020
Research Article
Open Access

Associations of Serological Biomarkers of sICAM-1, IL-1β, MIF, and su-PAR with 3-Month Mortality in Acute Exacerbation of Idiopathic Pulmonary Fibrosis

Xuran Li,  Ying Zhou,  Ruyi Zou,  Haoran Chen,  Xiaoqin Liu,  Xiaohua Qiu,  Yonglong Xiao,  Hourong Cai,  Jinghong Dai, 
  • First Published: 06 July 2020
Research Article
Open Access

The Pneumococcal Polysaccharide-Tetanus Toxin Native C-Fragment Conjugate Vaccine: The Carrier Effect and Immunogenicity

Rui Yu,  Junjie Xu,  Tao Hu,  Wei Chen, 
  • First Published: 04 July 2020
Research Article
Open Access

Anti-Inflammatory Effect of a Peptide Derived from the Synbiotics, Fermented Cudrania tricuspidata with Lactobacillus gasseri, on Inflammatory Bowel Disease

Jimyeong Ha,  Hyemin Oh,  Nam Su Oh,  Yeongeun Seo,  Joohyun Kang,  Min Hee Park,  Kyung Su Kim,  Shin Ho Kang,  Yohan Yoon, 
  • First Published: 04 July 2020
Research Article
Open Access

Inhibition of A2B Adenosine Receptor Attenuates Intestinal Injury in a Rat Model of Necrotizing Enterocolitis

Lie Huang,  Juan Fan,  Yan-Xiang Chen,  Jian-Hui Wang, 
  • First Published: 03 July 2020
Research Article
Open Access

Response of Human Mesenchymal Stromal Cells from Periodontal Tissue to LPS Depends on the Purity but Not on the LPS Source

Christian Behm,  Alice Blufstein,  Setareh Younes Abhari,  Christoph Koch,  Johannes Gahn,  Christina Schäffer,  Andreas Moritz,  Xiaohui Rausch-Fan,  Oleh Andrukhov, 
  • First Published: 02 July 2020
Research Article
Open Access

TREM-1 and TREM-2 Expression on Blood Monocytes Could Help Predict Survival in High-Grade Glioma Patients

K. Kluckova,  J. Kozak,  K. Szaboova,  B. Rychly,  M. Svajdler,  M. Suchankova,  E. Tibenska,  B. Filova,  J. Steno,  V. Matejcik,  M. Homolova,  M. Bucova, 
  • First Published: 01 July 2020
Research Article
Open Access

Study the Association of Tumor Necrosis Factor Promoter Polymorphism with Type 2 Diabetic Nephropathy

Mahmoud Emara,  Rawhia El-Edel,  Waleed M. Fathy,  Noran T. Aboelkhair,  Mona M. Watany,  Dalia H. Abou-Elela, 
  • First Published: 01 July 2020
Research Article
Open Access

Targeting Myeloid-Derived Suppressor Cells Is a Novel Strategy for Anti-Psoriasis Therapy

Chao Chen,  Lirong Tan,  Wu Zhu,  Li Lei,  Yehong Kuang,  Panpan Liu,  Jie Li,  Xiang Chen,  Cong Peng, 
  • First Published: 28 June 2020
Review Article
Open Access

Clinical Events Associated with Acupuncture Intervention for the Treatment of Chronic Inflammation Associated Disorders

Hua Bai,  Senlei Xu,  Qiulan Wu,  Shanshan Xu,  Ke Sun,  Jiahong Wu,  Xuefeng Xia,  Yuchen Liu,  Hongru Zhang,  Shengfeng Lu, 
  • First Published: 27 June 2020
Review Article
Open Access

The Effects of Dietary Nutrition on Sleep and Sleep Disorders

Mingxia Zhao,  Houzhen Tuo,  Shuhui Wang,  Lin Zhao, 
  • First Published: 25 June 2020
Research Article
Open Access

Mast Cell Activation, Neuroinflammation, and Tight Junction Protein Derangement in Acute Traumatic Brain Injury

Duraisamy Kempuraj,  Mohammad Ejaz Ahmed,  Govindhasamy Pushpavathi Selvakumar,  Ramasamy Thangavel,  Sudhanshu P. Raikwar,  Smita A. Zaheer,  Shankar S. Iyer,  Casey Burton,  Donald James,  Asgar Zaheer, 
  • First Published: 24 June 2020
Research Article
Open Access

Suppressors of Cytokine Signaling (SOCS)1 and SOCS3 Proteins Are Mediators of Interleukin-10 Modulation of Inflammatory Responses Induced by Chlamydia muridarum and Its Major Outer Membrane Protein (MOMP) in Mouse J774 Macrophages

Skyla A. Duncan,  Rajnish Sahu,  Saurabh Dixit,  Shree R. Singh,  Vida A. Dennis, 
  • First Published: 24 June 2020
Research Article
Open Access

Secoisolariciresinol Diglucoside Exerts Anti-Inflammatory and Antiapoptotic Effects through Inhibiting the Akt/IκB/NF-κB Pathway on Human Umbilical Vein Endothelial Cells

Shaoyang Zhang,  Meili Cheng,  Zhen Wang,  Yuzhi Liu,  Yuhua Ren,  Shikuo Rong,  Xue Wang, 
  • First Published: 24 June 2020
Research Article
Open Access

Diagnostic and Prognostic Value of IL-6 and sTREM-1 in SIRS and Sepsis in Children

Beata Smok,  Krzysztof Domagalski,  Małgorzata Pawłowska, 
  • First Published: 22 June 2020
Research Article
Open Access

Understanding Human Cerebral Malaria through a Blood Transcriptomic Signature: Evidences for Erythrocyte Alteration, Immune/Inflammatory Dysregulation, and Brain Dysfunction

Sandrine Cabantous,  Belco Poudiougou,  Aurélie Bergon,  Abdoulaye Barry,  Aboubacar A. Oumar,  Abdoulaye M. Traore,  Christophe Chevillard,  Ogobara Doumbo,  Alain Dessein,  Sandrine Marquet, 
  • First Published: 22 June 2020
Research Article
Open Access

RID: Evaluation of the Possible Inhibiting Effect of the Proinflammatory Signaling Induced by TNF-α through NF-κβ and AP-1 in Two Cell Lines of Breast Cancer

F. A. Monsalve,  A. Rojas,  I. Gonzalez,  R. Perez,  C. Añasco,  J. Romero,  P. Araya,  L. S. Santos,  F. Delgado-Lopez, 
  • First Published: 22 June 2020
Research Article
Open Access

Dexmedetomidine Attenuates Neurotoxicity in Developing Rats Induced by Sevoflurane through Upregulating BDNF-TrkB-CREB and Downregulating ProBDNF-P75NRT-RhoA Signaling Pathway

Yunxia Dong,  Wei Hong,  Zhiyin Tang,  Yan Gao,  Xiuying Wu,  Hongtao Liu, 
  • First Published: 20 June 2020
Research Article
Open Access

High-Pressure Pneumoperitoneum Aggravates Surgery-Induced Neuroinflammation and Cognitive Dysfunction in Aged Mice

Bo Lu,  Hui Yuan,  Xiaojie Zhai,  Xiaoyu Li,  Jinling Qin,  Junping Chen,  Bo Meng, 
  • First Published: 19 June 2020
Research Article
Open Access

miR-135a Alleviates Silica-Induced Pulmonary Fibrosis by Targeting NF-κB/Inflammatory Signaling Pathway

Bin Xie,  Can Lu,  Chen Chen,  Jianhua Zhou,  Zhenghao Deng, 
  • First Published: 17 June 2020
Corrigendum
Open Access

Corrigendum to “Macrophage Migration Inhibitory Factor Promotes the Interaction between the Tumor, Macrophages, and T Cells to Regulate the Progression of Chemically Induced Colitis-Associated Colorectal Cancer”

Thalia Pacheco-Fernández,  Imelda Juárez-Avelar,  Oscar Illescas,  Luis I. Terrazas,  Rogelio Hernández-Pando,  Carlos Pérez-Plasencia,  Emma B. Gutiérrez-Cirlos,  Federico Ávila-Moreno,  Yolanda I. Chirino,  José Luis Reyes,  Vilma Maldonado,  Miriam Rodriguez-Sosa, 
  • First Published: 17 June 2020

Research Article
Open Access

Sustained Immunoparalysis in Endotoxin-Tolerized Monocytic Cells

Christina K. Weisheit,  Alexandra Klüners,  Lennart Wild,  Alexandra Casalter,  Stefanie Heilmann-Heimbach,  Sugirthan Sivalingam,  Jan L. Kleiner,  Stefan F. Ehrentraut,  Andreas Hoeft,  Stilla Frede,  Heidi Ehrentraut, 
  • First Published: 13 June 2020
Review Article
Open Access

Tryptophan Metabolism, Regulatory T Cells, and Inflammatory Bowel Disease: A Mini Review

Xueyan Ding,  Peng Bin,  Wenwen Wu,  Yajie Chang,  Guoqiang Zhu, 
  • First Published: 12 June 2020
Research Article
Open Access

Pirfenidone Inhibits Hypoxic Pulmonary Hypertension through the NADPH/ROS/p38 Pathway in Adventitial Fibroblasts in the Pulmonary Artery

Song Zhang,  ZongXiu Yin,  WeiDong Qin,  XiaoLi Ma,  Yao Zhang,  EnXiu Liu,  YanBiao Chu, 
  • First Published: 11 June 2020
Research Article
Open Access

Amelioration of Coagulation Disorders and Inflammation by Hydrogen-Rich Solution Reduces Intestinal Ischemia/Reperfusion Injury in Rats through NF-κB/NLRP3 Pathway

Ling Yang,  Yan Guo,  Xin Fan,  Ye Chen,  Bo Yang,  Ke-Xuan Liu,  Jun Zhou, 
  • First Published: 10 June 2020
Research Article
Open Access

Decoy Receptor 3 Promotes Preosteoclast Cell Death via Reactive Oxygen Species-Induced Fas Ligand Expression and the IL-1α/IL-1 Receptor Antagonist Pathway

Yi-Jen Peng,  Ching-Tsung Peng,  Yi-Hsuan Lin,  Gu-Jiun Lin,  Shing-Hwa Huang,  Shyi-Jou Chen,  Huey-Kang Sytwu,  Chia-Pi Cheng, 
  • First Published: 10 June 2020
Research Article
Open Access

High Mean Platelet Volume Associates with In-Hospital Mortality in Severe Pneumonia Patients

Jieru Chen,  Yihao Li,  Yingsi Zeng,  Yu Tian,  Yueqiang Wen,  Zebin Wang, 
  • First Published: 08 June 2020
Research Article
Open Access

CD137 Signaling Promotes Endothelial Apoptosis by Inhibiting Nrf2 Pathway, and Upregulating NF-κB Pathway

Tianxin Geng,  Yang Yan,  Yue Zhang,  Liangjie Xu,  Guangyao Zang,  Jin Chuan Yan, 
  • First Published: 06 June 2020
Research Article
Open Access

Cytokine and Chemokine Profile in Patients with Multiple Myeloma Treated with Bortezomib

Paweł Robak,  Edyta Węgłowska,  Izabela Dróżdż,  Damian Mikulski,  Dariusz Jarych,  Magdalena Ferlińska,  Ewa Wawrzyniak,  Małgorzata Misiewicz,  Piotr Smolewski,  Wojciech Fendler,  Janusz Szemraj,  Tadeusz Robak, 
  • First Published: 06 June 2020
Research Article
Open Access

IL-17A in the Psoriatic Patients’ Serum and Plaque Scales as Potential Marker of the Diseases Severity and Obesity

Anna Michalak-Stoma,  Joanna Bartosińska,  Małgorzata Kowal,  Dorota Raczkiewicz,  Dorota Krasowska,  Grażyna Chodorowska, 
  • First Published: 05 June 2020
Research Article
Open Access

PCSK9 Expression in Epicardial Adipose Tissue: Molecular Association with Local Tissue Inflammation

Elena Dozio,  Massimiliano Ruscica,  Elena Vianello,  Chiara Macchi,  Clementina Sitzia,  Gerd Schmitz,  Lorenza Tacchini,  Massimiliano M. Corsi Romanelli, 
  • First Published: 04 June 2020
Research Article
Open Access

Progranulin Improves Acute Lung Injury through Regulating the Differentiation of Regulatory T Cells and Interleukin-10 Immunomodulation to Promote Macrophage Polarization

Yan-qing Chen,  Chuan-jiang Wang,  Ke Xie,  Ming Lei,  Yu-sen Chai,  Fang Xu,  Shi-hui Lin, 
  • First Published: 31 May 2020
Research Article
Open Access

Protein Level and Infantile Diarrhea in a Postweaning Piglet Model

Jing Gao,  Jie Yin,  Kang Xu,  Hui Han,  ZeMin Liu,  ChenYu Wang,  TieJun Li,  YuLong Yin, 
  • First Published: 31 May 2020
Research Article
Open Access

hnRNPA2/B1 Ameliorates LPS-Induced Endothelial Injury through NF-κB Pathway and VE-Cadherin/β-Catenin Signaling Modulation In Vitro

Yi Chen,  Dan Tang,  Linjie Zhu,  Tianjie Yuan,  Yingfu Jiao,  Hexin Yan,  Weifeng Yu, 
  • First Published: 30 May 2020
Research Article
Open Access

The Effects of Sidt2 on the Inflammatory Pathway in Mouse Mesangial Cells

Hui Sun,  Jia-ming Ding,  Hui-hao Zheng,  Kang-jia Lv,  Yun-fei Hu,  Ying-hui Luo,  Xue Wu,  Wen-jun Pei,  Li-zhuo Wang,  Ming-cai Wu,  Yao Zhang,  Jia-lin Gao, 
  • First Published: 28 May 2020
Review Article
Open Access

Exosomes: Potential Therapies for Disease via Regulating TLRs

Hong-Yan Guo,  An-Chun Cheng,  Ming-Shu Wang,  Zhong-Qiong Yin,  Ren-Yong Jia, 
  • First Published: 27 May 2020
Research Article
Open Access

Role of Colchicine Treatment in Tumor Necrosis Factor Receptor Associated Periodic Syndrome (TRAPS): Real-Life Data from the AIDA Network

Antonio Vitale,  Jurgen Sota,  Laura Obici,  Nicola Ricco,  Maria Cristina Maggio,  Marco Cattalini,  Piero Ruscitti,  Francesco Caso,  Raffaele Manna,  Ombretta Viapiana,  Valeria Caggiano,  Giacomo Emmi,  Antonella Insalaco,  Davide Montin,  Francesco Licciardi,  Alessandra Soriano,  Lorenzo Dagna,  Carlo Salvarani,  Vittoria Lamacchia,  José Hernández-Rodríguez,  Roberto Giacomelli,  Bruno Frediani,  Alessandra Renieri,  Luca Cantarini, 
  • First Published: 27 May 2020
Research Article
Open Access

Effects of GABA Supplementation on Intestinal SIgA Secretion and Gut Microbiota in the Healthy and ETEC-Infected Weanling Piglets

Yuanyuan Zhao,  Jing Wang,  Hao Wang,  Yonggang Huang,  Ming Qi,  Simeng Liao,  Peng Bin,  Yulong Yin, 
  • First Published: 26 May 2020
Research Article
Open Access

Prognostic Value of Pretreatment Systemic Immune-Inflammation Index in Glioblastoma Multiforme Patients Undergoing Postneurosurgical Radiotherapy Plus Concurrent and Adjuvant Temozolomide

Erkan Topkan,  Ali Ayberk Besen,  Yurday Ozdemir,  Ahmet Kucuk,  Huseyin Mertsoylu,  Berrin Pehlivan,  Ugur Selek, 
  • First Published: 23 May 2020
Research Article
Open Access

Dietary Magnesium Intake and Leukocyte Telomere Attrition in Adults: The Regulatory Role of Serum Tumor Necrosis Factor α

Jie Yu,  Haibin Liu,  Shuli He,  Pingping Li,  Chunxiao Ma,  Minglei Ma,  Yiwen Liu,  Lu Lv,  Fan Ping,  Huabing Zhang,  Wei Li,  Qi Sun,  Lingling Xu,  Yuxiu Li, 
  • First Published: 22 May 2020

Research Article
Open Access

High Concentrations of Uric Acid and Angiotensin II Act Additively to Produce Endothelial Injury

Quan Hong,  Liyuan Wang,  Zhiyong Huang,  Zhe Feng,  Shaoyuan Cui,  Bo Fu,  Guangyan Cai,  Xiangmei Chen,  Di Wu, 
  • First Published: 22 May 2020
Research Article
Open Access

miR-6869-5p Inhibits Glioma Cell Proliferation and Invasion via Targeting PGK1

Fakai Wang,  Huanjun Zhang,  Bing Liu,  Wei Liu,  Zengchao Zhang, 
  • First Published: 21 May 2020
Research Article
Open Access

Neutrophil to Lymphocyte Ratio Predicts Adverse Cardiovascular Outcome in Peritoneal Dialysis Patients Younger than 60 Years Old

Yingsi Zeng,  Zijun Chen,  Qinkai Chen,  Xiaojiang Zhan,  Haibo Long,  Fenfen Peng,  Fengping Zhang,  Xiaoran Feng,  Qian Zhou,  Lingling Liu,  Xuan Peng,  Evergreen Tree Nephrology Association,  Guanhua Guo,  Yujing Zhang,  Zebin Wang,  Yueqiang Wen,  Jiao Li,  Jianbo Liang, 
  • First Published: 20 May 2020
Research Article
Open Access

TLR7 Polymorphism (rs179008 and rs179009) in HIV-Infected Individual Naïve to ART

HariOm Singh,  Dharmesh Samani,  Sumit Aggarwal, 
  • First Published: 20 May 2020
Research Article
Open Access

Higher Levels of High-Sensitivity C-Reactive Protein Is Positively Associated with the Incidence of Hyperuricemia in Chinese Population: A Report from the China Health and Retirement Longitudinal Study

Hui-Xu Dai,  Zhi-Ying Zhao,  Yang Xia,  Qi-Jun Wu,  Yu-Hong Zhao, 
  • First Published: 20 May 2020
Research Article
Open Access

miR-199a-5p Exacerbated Intestinal Barrier Dysfunction through Inhibiting Surfactant Protein D and Activating NF-κB Pathway in Sepsis

Xianjin Du,  Dan Tian,  Jie Wei,  Chen Yan,  Peng Hu,  Xu Wu,  Wenbin Yang,  Zhanyong Zhu, 
  • First Published: 18 May 2020
Research Article
Open Access

Corticosterone Inhibits LPS-Induced NLRP3 Inflammasome Priming in Macrophages by Suppressing Xanthine Oxidase

Ling Wu,  Chengfu Zhou,  Jianfeng Wu,  Shikun Chen,  Zedan Tian,  Quan Du, 
  • First Published: 18 May 2020
Research Article
Open Access

Dynamic Monitoring of sTREM-1 and Other Biomarkers in Acute Cholangitis

Jiahui Jiang,  Xiaolei Wang,  Tongtong Cheng,  Mingyue Han,  Xinxin Wu,  Haitong Wan,  DaojunYu, 
  • First Published: 15 May 2020
Research Article
Open Access

Long-Term Outcomes of Behçet’s Syndrome-Related Uveitis: A Monocentric Italian Experience

Jurgen Sota,  Luca Cantarini,  Antonio Vitale,  Arianna Sgheri,  Stefano Gentileschi,  Valeria Caggiano,  Viviana Gelardi,  Bruno Frediani,  Gian Marco Tosi,  Claudia Fabiani, 
  • First Published: 15 May 2020
Research Article
Open Access

Relieving Sore Throat Formula Exerts a Therapeutic Effect on Pharyngitis through Immunoregulation and NF-κB Pathway

Yushi Ding,  Suyun Yu,  Zhonghong Wei,  Rui Deng,  Peng Chen,  Yifan Sun,  Qi Jia,  Xiaoman Li,  Yuanyuan Wu,  Wenxing Chen,  Kurt S. Zanker,  Aiyun Wang,  Yin Lu, 
  • First Published: 15 May 2020
Research Article
Open Access

TREM-1 and TREM-2 Expression on CD14+ Cells in Bronchoalveolar Lavage Fluid in Pulmonary Sarcoidosis and Hypersensitivity Pneumonitis in the Context of T Cell Immune Response

M. Suchankova,  J. Urban,  M. Ganovska,  E. Tibenska,  K. Szaboova,  E. Tedlova,  F. Sandor,  I. Majer,  M. Bobovcak,  I. Jonner,  B. Konig,  M. Bucova, 
  • First Published: 14 May 2020
Research Article
Open Access

Notch-Hes1 Signaling Regulates IL-17A+γδ+T Cell Expression and IL-17A Secretion of Mouse Psoriasis-Like Skin Inflammation

Yanqin Wang,  Xinxin Li,  Xiaoyun Xing,  Haibo Xue,  Ruiqun Qi,  Hong Ji,  Lei Ma, 
  • First Published: 12 May 2020
Research Article
Open Access

Sitagliptin on Carotid Intima-Media Thickness in Type 2 Diabetes Mellitus Patients and Anemia: A Subgroup Analysis of the PROLOGUE Study

Zhengri Lu,  Genshan Ma,  Lijuan Chen, 
  • First Published: 11 May 2020
Research Article
Open Access

Intravenous Arginine Administration Downregulates NLRP3 Inflammasome Activity and Attenuates Acute Kidney Injury in Mice with Polymicrobial Sepsis

Sharon Angela Tanuseputero,  Ming-Tsan Lin,  Sung-Ling Yeh,  Chiu-Li Yeh, 
  • First Published: 11 May 2020
Review Article
Open Access

Organ-Protective Effects and the Underlying Mechanism of Dexmedetomidine

Naren Bao,  Bing Tang, 
  • First Published: 09 May 2020
Research Article
Open Access

Exposure to Air Pollution Exacerbates Inflammation in Rats with Preexisting COPD

Jing Wang,  Ya Li,  Peng Zhao,  Yange Tian,  Xuefang Liu,  Huihui He,  Rui Jia,  Brian G. Oliver,  Jiansheng Li, 
  • First Published: 08 May 2020
Research Article
Open Access

Albumin-to-Fibrinogen Ratio Independently Predicts 28-Day Mortality in Patients with Peritonitis-Induced Sepsis

Huiyu Tai,  Zhiyun Zhu,  Haifeng Mei,  Wenbin Sun,  Wei Zhang, 
  • First Published: 06 May 2020
Research Article
Open Access

Loss of SNHG4 Attenuated Spinal Nerve Ligation-Triggered Neuropathic Pain through Sponging miR-423-5p

Xia Pan,  Cheng Shen,  Yayi Huang,  Long Wang,  Zhongyuan Xia, 
  • First Published: 06 May 2020

Research Article
Open Access

The Role of Matrix Metalloproteinases (MMP-2 and MMP-9) in Ageing and Longevity: Focus on Sicilian Long-Living Individuals (LLIs)

Patrizia Cancemi,  Anna Aiello,  Giulia Accardi,  Rosalia Caldarella,  Giuseppina Candore,  Calogero Caruso,  Marcello Ciaccio,  Laura Cristaldi,  Francesca Di Gaudio,  Valentina Siino,  Sonya Vasto, 
  • First Published: 05 May 2020
Research Article
Open Access

Associations between Interleukin Gene Polymorphisms and Risks of Developing Extremity Posttraumatic Osteomyelitis in Chinese Han Population

Nan Jiang,  Su-yi Li,  Yun-fei Ma,  Yan-jun Hu,  Qing-rong Lin,  Bin Yu, 
  • First Published: 05 May 2020
Review Article
Open Access

Detection and Prognosis of Prostate Cancer Using Blood-Based Biomarkers

Wei Jin,  Xiang Fei,  Xia Wang,  Yan Song,  Fangjie Chen, 
  • First Published: 04 May 2020
Review Article
Open Access

Regulation of Iron Homeostasis and Related Diseases

Yikun Li,  Xiali Huang,  Jingjing Wang,  Ruiling Huang,  Dan Wan, 
  • First Published: 02 May 2020
Research Article
Open Access

Calprotectin as a New Sensitive Marker of Neutrophilic Inflammation in Patients with Bronchiolitis Obliterans

S. P. Jerkic,  F. Michel,  H. Donath,  E. Herrmann,  R. Schubert,  M. Rosewich,  S. Zielen, 
  • First Published: 01 May 2020
Research Article
Open Access

Identification of miRNA-mRNA Crosstalk in Respiratory Syncytial Virus- (RSV-) Associated Pediatric Pneumonia through Integrated miRNAome and Transcriptome Analysis

Xu Zhang,  Feng Huang,  Diyuan Yang,  Tao Peng,  Gen Lu, 
  • First Published: 01 May 2020
Research Article
Open Access

Reevaluation of Lung Injury in TNF-Induced Shock: The Role of the Acid Sphingomyelinase

Lucy K. Reiss,  Ute Raffetseder,  Lydia Gibbert,  Hannah K. Drescher,  Konrad L. Streetz,  Agatha Schwarz,  Christian Martin,  Stefan Uhlig,  Dieter Adam, 
  • First Published: 01 May 2020
Research Article
Open Access

Chitosan-Based Nanoparticles for Intracellular Delivery of ISAV Fusion Protein cDNA into Melanoma Cells: A Path to Develop Oncolytic Anticancer Therapies

Claudia Robles-Planells,  Giselle Sánchez-Guerrero,  Carlos Barrera-Avalos,  Silvia Matiacevich,  Leonel E. Rojo,  Jorge Pavez,  Edison Salas-Huenuleo,  Marcelo J. Kogan,  Alejandro Escobar,  Luis A. Milla,  Ricardo Fernandez,  Mónica Imarai,  Eugenio Spencer,  Juan Pablo Huidobro-Toro,  Claudio Acuña-Castillo, 
  • First Published: 29 April 2020
Research Article
Open Access

Carbon Monoxide-Releasing Molecule-3 Suppresses Tumor Necrosis Factor-α- and Interleukin-1β-Induced Expression of Junctional Molecules on Human Gingival Fibroblasts via the Heme Oxygenase-1 Pathway

Jia Lv,  Yongsheng Liu,  Shuhan Jia,  Yuna Zhang,  Haoyang Tian,  Jingyuan Li,  Hui Song, 
  • First Published: 28 April 2020
Research Article
Open Access

Age-Related Differences in the Association between Plasma High-Sensitivity C-Reactive Protein and Noncalcified or Mixed Coronary Atherosclerotic Plaques

Tiewei Li,  Ning Chen,  Zhengan Liu,  Zhiming Shan,  Geng Dong,  Junmei Yang,  Minglu Qi, 
  • First Published: 28 April 2020
Research Article
Open Access

Association of Brain-Gut Peptides with Inflammatory Cytokines in Moyamoya Disease

Wenxiu Han,  Feng Jin,  Hailiang Zhang,  Mengqi Yang,  Changmeng Cui,  Changshui Wang,  Pei Jiang, 
  • First Published: 28 April 2020
Research Article
Open Access

Carotenoids Inhibit Fructose-Induced Inflammatory Response in Human Endothelial Cells and Monocytes

Ping Lin,  Qian Ren,  Qin Wang,  Jiali Wu, 
  • First Published: 28 April 2020
Research Article
Open Access

Global Transcriptional Profiling Reveals Novel Autocrine Functions of Interleukin 6 in Human Vascular Endothelial Cells

Liza U. Ljungberg,  Mulugeta M. Zegeye,  Caroline Kardeby,  Knut Fälker,  Dirk Repsilber,  Allan Sirsjö, 
  • First Published: 28 April 2020
Research Article
Open Access

The Role of MIF-173G/C Gene Polymorphism in the Susceptibility of Autoimmune Diseases

Xiangrong Du,  Ruixia Li,  Shoujun Song,  Lei Ma,  Haibo Xue, 
  • First Published: 28 April 2020
Research Article
Open Access

Autophagy Contributes to Host Immunity and Protection against Zika Virus Infection via Type I IFN Signaling

Yuyi Huang,  Yujie Wang,  Shuhui Meng,  Zhuohang Chen,  Haifan Kong,  Ting Pan,  Gen Lu,  Xuefeng Li, 
  • First Published: 28 April 2020
Research Article
Open Access

Fibrinogen as a Prognostic Predictor in Pediatric Patients with Sepsis: A Database Study

Xiaomeng Tang,  Lujing Shao,  Jiaying Dou,  Yiping Zhou,  Min Chen,  Yun Cui,  Yucai Zhang,  Chunxia Wang, 
  • First Published: 28 April 2020

Clinical Study
Open Access

Pioglitazone Metformin Complex Improves Polycystic Ovary Syndrome Comorbid Psychological Distress via Inhibiting NLRP3 Inflammasome Activation: A Prospective Clinical Study

Qing-jun Guo,  Jing Shan,  Yi-feng Xu,  Yan-yan Hu,  Cui-lan Huo,  Jing-yun Song,  Chao-qun Wang,  Hui Zhou,  Chao-qin Yu,  Qin Huang, 
  • First Published: 28 April 2020
Research Article
Open Access

Effects of Compressive and Tensile Strain on Macrophages during Simulated Orthodontic Tooth Movement

Agnes Schröder,  Paul Käppler,  Ute Nazet,  Jonathan Jantsch,  Peter Proff,  Fabian Cieplik,  James Deschner,  Christian Kirschneck, 
  • First Published: 28 April 2020
Research Article
Open Access

Antagonistic Peptides That Specifically Bind to the First and Second Extracellular Loops of CCR5 and Anti-IL-23p19 Antibody Reduce Airway Inflammation by Suppressing the IL-23/Th17 Signaling Pathway

Yingli Zhang,  Rongrong Liang,  Aicen Xie,  Wenqian Shi,  Huarong Huang,  Yingqiang Zhong, 
  • First Published: 28 April 2020
Research Article
Open Access

IL-33 Inhibits Hepatitis B Virus through Its Receptor ST2 in Hydrodynamic HBV Mouse Model

Xiuzhu Gao,  Xiumei Chi,  Xiaomei Wang,  Ruihong Wu,  Hongqin Xu,  MengRu Zhan,  Dong Li,  Yanhua Ding,  Damo Xu,  Junqi Niu, 
  • First Published: 28 April 2020
Research Article
Open Access

Enhanced Wound Healing- and Inflammasome-Associated Gene Expression in TNFAIP3-Interacting Protein 1- (TNIP1-) Deficient HaCaT Keratinocytes Parallels Reduced Reepithelialization

Rambon Shamilov,  Tyler W. Ackley,  Brian J. Aneskievich, 
  • First Published: 21 April 2020
Research Article
Open Access

Anti-Inflammatory and Antioxidant Activities of the Methanolic Extract of Cyrtocarpa procera Bark Reduces the Severity of Ulcerative Colitis in a Chemically Induced Colitis Model

Mario Rodriguez-Canales,  Elizdath Martinez-Galero,  Alma D. Nava-Torres,  Luvia E. Sanchez-Torres,  Leticia Garduño-Siciliano,  Maria Margarita Canales-Martinez,  Luis I. Terrazas,  Marco A. Rodriguez-Monroy, 
  • First Published: 21 April 2020
Research Article
Open Access

Predictors for Short-Term Efficacy of Allergen-Specific Sublingual Immunotherapy in Children with Allergic Rhinitis

Wenlong Liu,  Qingxiang Zeng,  Renzhong Luo, 
  • First Published: 21 April 2020
Review Article
Open Access

Role of Mitochondrial Stress Protein HSP60 in Diabetes-Induced Neuroinflammation

Donisha Shani Niharika Keembiya Liyanagamage,  Ryan D. Martinus, 
  • First Published: 19 April 2020
Review Article
Open Access

Density of Langerhans Cells in Nonmelanoma Skin Cancers: A Systematic Review

Joanna Pogorzelska-Dyrbuś,  Jacek C. Szepietowski, 
  • First Published: 19 April 2020
Clinical Study
Open Access

Both Low and High Postprocedural hsCRP Associate with Increased Risk of Death in Acute Coronary Syndrome Patients Treated by Percutaneous Coronary Intervention

Runzhen Chen,  Chen Liu,  Peng Zhou,  Yu Tan,  Zhaoxue Sheng,  Jiannan Li,  Jinying Zhou,  Yi Chen,  Li Song,  Hanjun Zhao,  Hongbing Yan, 
  • First Published: 17 April 2020
Research Article
Open Access

Decreased Plasma Maresin 1 Concentration Is Associated with Diabetic Foot Ulcer

Tian Miao,  Bangliang Huang,  Niexia He,  Lihua Sun,  Guangsheng Du,  Xiaoli Gong,  Yong Xu,  Yi Zheng,  Hongting Zheng,  Hua Qu, 
  • First Published: 16 April 2020
Research Article
Open Access

Inhibition of GPR91 Reduces Inflammatory Mediators Involved in Active Labor in Myometrium

Ratana Lim,  Martha Lappas, 
  • First Published: 15 April 2020
Research Article
Open Access

Sodium Butyrate Protects N2a Cells against Aβ Toxicity In Vitro

Jingxuan Sun,  Boyu Yuan,  Yancheng Wu,  Yuhong Gong,  Wenjin Guo,  Shoupeng Fu,  Yongxin Luan,  Wei Wang, 
  • First Published: 15 April 2020
Research Article
Open Access

Alarmins HMGB1, IL-33, S100A7, and S100A12 in Psoriasis Vulgaris

Pavel Borsky,  Zdenek Fiala,  Ctirad Andrys,  Martin Beranek,  Kvetoslava Hamakova,  Andrea Malkova,  Tereza Svadlakova,  Jan Krejsek,  Vladimir Palicka,  Lenka Borska,  Vit Rehacek, 
  • First Published: 15 April 2020
Research Article
Open Access

Diallyl Disulfide Suppresses Inflammatory and Oxidative Machineries following Carrageenan Injection-Induced Paw Edema in Mice

Hongxing Zhang,  Chi Shang,  Zhao Tian,  Hatem K. Amin,  Rami B. Kassab,  Ahmed E. Abdel Moneim,  Yingang Zhang, 
  • First Published: 15 April 2020
Research Article
Open Access

Decreased Soluble Receptor of Advanced Glycation End Product Levels Correlated with Inflammation in Silicosis

Heliang Liu,  Jingjing Ma,  Tian Jiang,  Enhong Li,  Xiaokun Zhao,  Ying Wang,  Jie Cui,  Xiaohui Hao,  Lingli Guo, 
  • First Published: 14 April 2020
Research Article
Open Access

Methimazole Inhibits the Expression of GFAP and the Migration of Astrocyte in Scratched Wound Model In Vitro

Lina Zhao,  Xianyu Zhang,  Chunhai Zhang, 
  • First Published: 13 April 2020
Review Article
Open Access

Synovial Macrophages in Rheumatoid Arthritis: The Past, Present, and Future

Jiajie Tu,  Xinming Wang,  Xun Gong,  Wenming Hong,  Dafei Han,  Yilong Fang,  Yawei Guo,  Wei Wei, 
  • First Published: 13 April 2020
Research Article
Open Access

Anti-Inflammatory Profile of Jungia sellowii Less. by Downregulation of Proinflammatory Mediators and Inhibition of NF-κB and p38 Pathways

Geison Vicente,  Yeo Jim Kinoshita Moon,  Daniela Weingärtner Rosa,  Luíse Azevedo Lima,  Najla Adel Saleh,  Julia Salvan da Rosa,  Tânia Beatriz Creczynski-Pasa,  Maique Weber Biavatti,  Eduardo Monguilhott Dalmarco,  Tânia Silvia Fröde, 
  • First Published: 11 April 2020
Research Article
Open Access

MitoQ Modulates Lipopolysaccharide-Induced Intestinal Barrier Dysfunction via Regulating Nrf2 Signaling

Shengfeng Zhang,  Qingniao Zhou,  Youcheng Li,  Yunli Zhang,  Yinmei Wu, 
  • First Published: 11 April 2020
Research Article
Open Access

Identification of Hub Genes Related to Carcinogenesis and Prognosis in Colorectal Cancer Based on Integrated Bioinformatics

Benjiao Gong,  Yanlei Kao,  Chenglin Zhang,  Fudong Sun,  Zhaohua Gong,  Jian Chen, 
  • First Published: 09 April 2020
Research Article
Open Access

The Plasma Soluble Urokinase Plasminogen Activator Receptor Is Related to Disease Activity of Patients with ANCA-Associated Vasculitis

Fei Huang,  Yueqiang Li,  Ranran Xu,  Anying Cheng,  Yongman Lv,  Qingquan Liu, 
  • First Published: 07 April 2020
Research Article
Open Access

The Supernatant of Tonsil-Derived Mesenchymal Stem Cell Has Antiallergic Effects in Allergic Rhinitis Mouse Model

In-Su Park,  Ji Hye Kim,  Jun-Sang Bae,  Dong-Kyu Kim,  Ji-Hun Mo, 
  • First Published: 07 April 2020
Research Article
Open Access

Assessment of Arf6 Deletion in PLB-985 Differentiated in Neutrophil-Like Cells and in Mouse Neutrophils: Impact on Adhesion and Migration

Jouda Gamara,  Lynn Davis,  Emmanuelle Rollet-Labelle,  Tsunaki Hongu,  Yuji Funakoshi,  Yasunori Kanaho,  Fawzi Aoudjit,  Sylvain G. Bourgoin, 
  • First Published: 07 April 2020
Research Article
Open Access

The Expression of IL-12 Family Members in Patients with Hypertension and Its Association with the Occurrence of Carotid Atherosclerosis

Jing Ye,  Yuan Wang,  Zhen Wang,  Ling Liu,  Zicong Yang,  Menglong Wang,  Yao Xu,  Di Ye,  Jishou Zhang,  Qi Zhou,  Yingzhong Lin,  Qingwei Ji,  Jun Wan, 
  • First Published: 06 April 2020
Review Article
Open Access

Mycobiome in the Gut: A Multiperspective Review

Voon Kin Chin,  Voon Chen Yong,  Pei Pei Chong,  Syafinaz Amin Nordin,  Rusliza Basir,  Maha Abdullah, 
  • First Published: 04 April 2020
Research Article
Open Access

Dietary Supplementation of L-Arginine and N-Carbamylglutamate Attenuated the Hepatic Inflammatory Response and Apoptosis in Suckling Lambs with Intrauterine Growth Retardation

Hao Zhang,  Yaotian Fan,  Mabrouk Elsabagh,  Shuang Guo,  Mengzhi Wang,  Honghua Jiang, 
  • First Published: 04 April 2020
Research Article
Open Access

Dexmedetomidine Protects against Ischemia and Reperfusion-Induced Kidney Injury in Rats

Naren Bao,  Di Dai, 
  • First Published: 03 April 2020
Research Article
Open Access

Endocan: A Biomarker for Hepatosteatosis in Patients with Metabolic Syndrome

Hande Erman,  Engin Beydogan,  Seher Irem Cetin,  Banu Boyuk, 
  • First Published: 01 April 2020
Research Article
Open Access

Long-Term Effectiveness of Secukinumab in Patients with Axial Spondyloarthritis

Stefano Gentileschi,  Donato Rigante,  Jurgen Sota,  Giuseppe Lopalco,  Maria Grazia Giannotta,  Giacomo Emmi,  Gerardo Di Scala,  Florenzo Iannone,  Claudia Fabiani,  Bruno Frediani,  Luca Cantarini, 
  • First Published: 31 March 2020
Research Article
Open Access

CXCL14 Overexpression Attenuates Sepsis-Associated Acute Kidney Injury by Inhibiting Proinflammatory Cytokine Production

Jing Lv,  Zhi-Lin Wu,  Zheng Gan,  Ping Gui,  Shang-Long Yao, 
  • First Published: 31 March 2020
Research Article
Open Access

High CD163 Expression on Classical Monocytes Is Associated with Immune Control of HBV Infection in Noncirrhotic Patients

Anna Parfieniuk-Kowerda,  Kamil Grubczak,  Andrzej Eljaszewicz,  Magdalena Świderska,  Magdalena Maciaszek,  Anatol Panasiuk,  Jerzy Jaroszewicz,  Robert Flisiak,  Marcin Moniuszko, 
  • First Published: 29 March 2020
Research Article
Open Access

Complement Activation in Association with Markers of Neutrophil Extracellular Traps and Acute Myocardial Infarction in Stable Coronary Artery Disease

Karsten E. Kluge,  Miriam S. Langseth,  Trine B. Opstad,  Alf Å. Pettersen,  Harald Arnesen,  Theis Tønnessen,  Ingebjørg Seljeflot,  Ragnhild Helseth, 
  • First Published: 26 March 2020
Research Article
Open Access

Assessment of Selected Parameters of Liver Fibrosis and Inflammation in Patients with Diagnosed Cystic Fibrosis

Sabina Więcek,  Halina Woś,  Andrzej Pogorzelski,  Bożena Kordys-Darmolinska,  Henryk Mazurek,  Urszula Grzybowska-Chlebowczyk, 
  • First Published: 25 March 2020
Review Article
Open Access

Resolution of Inflammation in Neurodegenerative Diseases: The Role of Resolvins

Sajad Chamani,  Vanessa Bianconi,  Aida Tasbandi,  Matteo Pirro,  George E. Barreto,  Tannaz Jamialahmadi,  Amirhossein Sahebkar, 
  • First Published: 25 March 2020
Review Article
Open Access

Perspectives in HPV Secondary Screening and Personalized Therapy Basing on Our Understanding of HPV-Related Carcinogenesis Pathways

Aleksander Celewicz,  Marta Celewicz,  Michał Michalczyk,  Rafał Rzepka, 
  • First Published: 25 March 2020
Research Article
Open Access

ADAR1 Alleviates Inflammation in a Murine Sepsis Model via the ADAR1-miR-30a-SOCS3 Axis

Zhou Shangxun,  Li Junjie,  Zhao Wei,  Wang Yutong,  Jia Wenyuan,  Liu Shanshou,  Wang Yanjun,  Wang Qianmei,  Feng Zhusheng,  Yu Chaoping,  Zhuang Ran,  Yin Wen,  Huang Yang, 
  • First Published: 24 March 2020
Research Article
Open Access

Protein Kinase A Is Involved in Neuropathic Pain by Activating the p38MAPK Pathway to Mediate Spinal Cord Cell Apoptosis

Yajun Deng,  Liang Yang,  Qiqi Xie,  Fengbiao Yang,  Guoqiang Li,  Guangzhi Zhang,  Shaoping Li,  Zuolong Wu,  Jing Wang,  Xuewen Kang, 
  • First Published: 23 March 2020
Research Article
Open Access

Leukotriene Pathway Activation Associates with Poor Glycemic Control and with Cardiovascular Autonomic Neuropathy in Type 1 Diabetes

Daniele P. Santos-Bezerra,  Luciano R. Filgueiras,  Maria Beatriz Monteiro,  Sharon N. Admoni,  Ricardo V. Perez,  Ana M. Cavaleiro,  Cleide G. Machado,  Ubiratan F. Machado,  Marisa Passarelli,  Sonia Jancar,  Maria Lucia Correa-Giannella, 
  • First Published: 23 March 2020
Research Article
Open Access

The Enlargement of Abdominal Lymph Nodes Is a Characteristic of Autoimmune Liver Disease

Yongjuan Wang,  Xiuxiu Xu,  Maojuan Ran,  Xiaopei Guo,  Lu Zhou,  Xi Wang,  Bangmao Wang,  Jie Zhang, 
  • First Published: 21 March 2020
Editorial
Open Access

Dendritic Cells: Immune Response in Infectious Diseases and Autoimmunity

Renata Sesti-Costa,  Pedro Manoel Mendes de Moraes-Vieira,  Luisa Cervantes-Barragan, 
  • First Published: 20 March 2020
Review Article
Open Access

Immunophenotypic Profiles in Polycystic Ovary Syndrome

Cong Hu,  Bo Pang,  Zhanchuan Ma,  Huanfa Yi, 
  • First Published: 19 March 2020
Review Article
Open Access

Molecular and Cellular Pathways Contributing to Joint Damage in Rheumatoid Arthritis

Qinghua Fang,  Chun Zhou,  Kutty Selva Nandakumar, 
  • First Published: 17 March 2020
Review Article
Open Access

The Therapeutic Potential of MicroRNAs in Atrial Fibrillation

Xiaona Xu,  Zhiqiang Zhao,  Guangping Li, 
  • First Published: 12 March 2020
Research Article
Open Access

Cells and Cytokines in Milk of Subclinically Infected Bovine Mammary Glands after the Use of Immunomodulatory Composition GLP 810

Gundega Gulbe,  Māra Pilmane,  Vaira Saulīte,  Simona Doniņa,  Jevgenijs Jermolajevs,  Lilija Peškova,  Anda Valdovska, 
  • First Published: 10 March 2020
Research Article
Open Access

I-alowCD11bhigh DC Regulates the Immune Response in the Eyes of Experimental Autoimmune Uveitis

Yu Zhao,  Jingwen Wang,  Zhang Min,  Li Peng,  Shuhong Qi,  Wei Lin, 
  • First Published: 10 March 2020

Research Article
Open Access

Proinflammatory Effects of Ubiquitin-Specific Protease 5 (USP5) in Rheumatoid Arthritis Fibroblast-Like Synoviocytes

Xiao-Bo Luo,  Jian-Cheng Xi,  Zhen Liu,  Yu Long,  Li-tao Li,  Zhan-Peng Luo,  Dao-Hong Liu, 
  • First Published: 09 March 2020
Research Article
Open Access

Leptin Regulated ILC2 Cell through the PI3K/AKT Pathway in Allergic Rhinitis

Qingxiang Zeng,  Xi Luo,  Yiquan Tang,  Wenlong Liu,  Renzhong Luo, 
  • First Published: 07 March 2020
Research Article
Open Access

Multiple Anesthesia/Surgery Cannot Impair Reference Memory in Adult Mice

Xiaoxin Zhou,  Jian Lu,  Tong Wu,  Xuliang Jiang,  Weitian Tian,  Wanbing Dai,  Siyi Qi,  Xuemei Chen,  Jiaqiang Zhang,  Diansan Su, 
  • First Published: 07 March 2020
Research Article
Open Access

Assessing the Effects of Parthenolide on Inflammation, Bone Loss, and Glial Cells within a Collagen Antibody-Induced Arthritis Mouse Model

B. Williams,  F. Lees,  H. Tsangari,  M. R. Hutchinson,  E. Perilli,  T. N. Crotti, 
  • First Published: 04 March 2020
Editorial
Open Access

Vision for Mediators of Inflammation

Anshu Agrawal, 
  • First Published: 04 March 2020
Review Article
Open Access

The Role of Inflammation in the Pathogenesis of Osteoarthritis

Yoke Yue Chow,  Kok-Yong Chin, 
  • First Published: 03 March 2020
Research Article
Open Access

Serine Deficiency Exacerbates Inflammation and Oxidative Stress via Microbiota-Gut-Brain Axis in D-Galactose-Induced Aging Mice

Fengen Wang,  Hongbin Zhou,  Ligang Deng,  Lei Wang,  Jingqing Chen,  Xihong Zhou, 
  • First Published: 02 March 2020
Research Article
Open Access

Nicotine Impairs the Response of Lung Epithelial Cells to IL-22

Hannah My-Hanh Nguyen,  Jaclene Amber Torres,  Sudhanshu Agrawal,  Anshu Agrawal, 
  • First Published: 29 February 2020
Research Article
Open Access

Three Ingredients of Safflower Alleviate Acute Lung Injury and Inhibit NET Release Induced by Lipopolysaccharide

Yun-peng Wang,  Yu Guo,  Ping-shan Wen,  Zhen-zhen Zhao,  Jian Xie,  Kai Yang,  Qing Yang,  Jia-feng Wang,  Xiao-ming Deng, 
  • First Published: 29 February 2020
Research Article
Open Access

Recombinant Erythropoietin Provides Protection against Renal Fibrosis in Adenine-Induced Chronic Kidney Disease

Estefanía Vázquez-Méndez,  Yanet Gutiérrez-Mercado,  Edgar Mendieta-Condado,  Francisco Javier Gálvez-Gastélum,  Hugo Esquivel-Solís,  Yadira Sánchez-Toscano,  Claudia Morales-Martínez,  Alejandro A. Canales-Aguirre,  Ana Laura Márquez-Aguirre, 
  • First Published: 27 February 2020
Research Article
Open Access

Triticum vulgare Extract Modulates Protein-Kinase B and Matrix Metalloproteinases 9 Protein Expression in BV-2 Cells: Bioactivity on Inflammatory Pathway Associated with Molecular Mechanism Wound Healing

Niccola Funel,  Valentina Dini,  Agata Janowska,  Barbara Loggini,  Massimiliano Minale,  Fabrizia Grieco,  Salvatore Riccio,  Marco Romanelli, 
  • First Published: 27 February 2020
Review Article
Open Access

The Interplay between Immune System and Microbiota in Osteoporosis

Pietro Locantore,  Valeria Del Gatto,  Silvia Gelli,  Rosa Maria Paragliola,  Alfredo Pontecorvi, 
  • First Published: 26 February 2020
Research Article
Open Access

The Mast Cell Is an Early Activator of Lipopolysaccharide-Induced Neuroinflammation and Blood-Brain Barrier Dysfunction in the Hippocampus

Yiwei Wang,  Huanhuan Sha,  Leting Zhou,  Yinan Chen,  Qin Zhou,  Hongquan Dong,  Yanning Qian, 
  • First Published: 24 February 2020
Research Article
Open Access

Effects of Shikonin on the Functions of Myeloid Dendritic Cells in a Mouse Model of Severe Aplastic Anemia

Mengying Zheng,  Bingnan Liu,  Yuanyuan Shao,  Luogang Hua,  Rong Fu,  Huaquan Wang,  Ting Wang,  Weiwei Qi,  Zonghong Shao,  Chunyan Liu, 
  • First Published: 20 February 2020
Research Article
Open Access

Phenotypic and Functional Changes in Peripheral Blood Natural Killer Cells in Crohn Disease Patients

Suzanne Samarani,  Patrick Sagala,  Prevost Jantchou,  Guy Grimard,  Christophe Faure,  Colette Deslandres,  Devendra K. Amre,  Ali Ahmad, 
  • First Published: 19 February 2020
Research Article
Open Access

Interleukin-22 Polymorphisms in Plasmodium falciparum-Infected Malaria Patients

Nada H. Aljarba,  Mashael R. Al-Anazi,  Mohammed I. Shafeai,  Fuad H. Rudiny,  Saad M. Bin Dajem,  Hani Alothaid,  Majid Darraj,  Saad Alkahtani,  Jahad Alghamdi,  Mohammed N. Al-Ahdal,  Ahmed A. Al-Qahtani, 
  • First Published: 19 February 2020
Review Article
Open Access

Trimethylamine N-Oxide Generated by the Gut Microbiota Is Associated with Vascular Inflammation: New Insights into Atherosclerosis

Yarong Liu,  Min Dai, 
  • First Published: 17 February 2020
Research Article
Open Access

Monocyte/Lymphocyte Ratio and Cardiovascular Disease Mortality in Peritoneal Dialysis Patients

Yueqiang Wen,  Xiaojiang Zhan,  Niansong Wang,  FenFen Peng,  Xiaoran Feng,  Xianfeng Wu, 
  • First Published: 17 February 2020
Research Article
Open Access

Interleukin-9 Deletion Relieves Vascular Dysfunction and Decreases Blood Pressure via the STAT3 Pathway in Angiotensin II-Treated Mice

Yunzhao Yang,  Shaoqun Tang,  Chunchun Zhai,  Xin Zeng,  Qingjian Liu,  Cheng Xu,  Hexiang Chen, 
  • First Published: 14 February 2020

Research Article
Open Access

Defects of CTLA-4 Are Associated with Regulatory T Cells in Myasthenia Gravis Implicated by Intravenous Immunoglobulin Therapy

Wenhua Xu,  Mingshan Ren,  Swagata Ghosh,  Kai Qian,  Zhaofeng Luo,  Aimei Zhang,  Cuiping Zhang,  Jiajun Cui, 
  • First Published: 14 February 2020
Research Article
Open Access

Dietary Supplemental Glutamine Enhances the Percentage of Circulating Endothelial Progenitor Cells in Mice with High-Fat Diet-Induced Obesity Subjected to Hind Limb Ischemia

Chi-Hsuan Ko,  Sung-Ling Yeh,  Chiu-Li Yeh, 
  • First Published: 13 February 2020
Research Article
Open Access

The Prognostic Impact of Circulating Regulatory T Lymphocytes on Mortality in Patients with Ischemic Heart Failure with Reduced Ejection Fraction

Andreas Hammer,  Patrick Sulzgruber,  Lorenz Koller,  Niema Kazem,  Felix Hofer,  Bernhard Richter,  Steffen Blum,  Martin Hülsmann,  Johann Wojta,  Alexander Niessner, 
  • First Published: 10 February 2020
Research Article
Open Access

Dexmedetomidine Attenuates Monocyte-Endothelial Adherence via Inhibiting Connexin43 on Vascular Endothelial Cells

Yunfei Chai,  Runying Yu,  Yong Liu,  Sheng Wang,  Dongdong Yuan,  Jimei Chen, 
  • First Published: 10 February 2020
Research Article
Open Access

Paeonol Attenuates Methotrexate-Induced Cardiac Toxicity in Rats by Inhibiting Oxidative Stress and Suppressing TLR4-Induced NF-κB Inflammatory Pathway

Abdulla Y. Al-Taher,  Mohamed A. Morsy,  Rehab A. Rifaai,  Nagwa M. Zenhom,  Seham A. Abdel-Gaber, 
  • First Published: 10 February 2020
Research Article
Open Access

CD19+CD24hiCD38hi B Cell Dysfunction in Primary Biliary Cholangitis

Qubo Chen,  Lanmin Lai,  Xiaoling Chi,  Xinyi Lu,  Huaxian Wu,  Jing Sun,  Weilin Wu,  Li Cai,  Xuan Zeng,  Chuyang Wang,  WeiCheng Chen,  Anping Peng, 
  • First Published: 10 February 2020
Research Article
Open Access

Monocytes Undergo Functional Reprogramming to Generate Immunosuppression through HIF-1α Signaling Pathway in the Late Phase of Sepsis

Li-Li Li,  Bing Dai,  Yu-Han Sun,  Ting-Ting Zhang, 
  • First Published: 07 February 2020
Research Article
Open Access

Aloe Emodin Reduces Cardiac Inflammation Induced by a High-Fat Diet through the TLR4 Signaling Pathway

Yingfu Chen,  Burong Feng,  Ye Yuan,  Juan Hu,  Wei Zhao,  Huiwei Jiang,  Wen Li,  Ziyi Fan,  Zhimin Du, 
  • First Published: 05 February 2020
Review Article
Open Access

Role of Chemokine (C–X–C Motif) Ligand 10 (CXCL10) in Renal Diseases

Jie Gao,  Lingling Wu,  Siyang Wang,  Xiangmei Chen, 
  • First Published: 05 February 2020
Research Article
Open Access

Depression of lncRNA NEAT1 Antagonizes LPS-Evoked Acute Injury and Inflammatory Response in Alveolar Epithelial Cells via HMGB1-RAGE Signaling

Hongchao Zhou,  Xinhui Wang,  Bin Zhang, 
  • First Published: 05 February 2020
Review Article
Open Access

Possible Mechanisms Involved in the Cooccurrence of Oral Lichen Planus and Hashimoto’s Thyroiditis

Peiyao Wu,  Shuhan Luo,  Tao Zhou,  Rui Wang,  Xuemei Qiu,  Peiyang Yuan,  Yuqing Yang,  Qi Han,  Lu Jiang, 
  • First Published: 04 February 2020
Research Article
Open Access

Regulation of Cyclooxygenase 2 by Filifactor alocis in Fibroblastic and Monocytic Cells

Marjan Nokhbehsaim,  Andressa V. B. Nogueira,  Sandor Nietzsche,  Sigrun Eick,  James Deschner, 
  • First Published: 03 February 2020
Research Article
Open Access

In Vitro Anti-Inflammatory, Anticancer (MCF-7, 3T3, and HeLa Cell Lines), and Brine Shrimp Lethality Assay and FTIR Analysis of the Extract and Fractions of the Whole Plant of Heliotropium europaeum

Jahangir Khan Achakzai,  Muhammad Anwar Panezai,  Basira Akhtar,  Shahabuddin Kakar,  Ali Akbar,  Abdul Manan Kakar,  Javed Khan,  Nazima Yousaf Khan,  Ghulam Mustafa Khan,  Muhammad Imran,  Marina Panezai,  Nisar Ahmed Shahwani,  Tehmina Achakzai, 
  • First Published: 01 February 2020
Research Article
Open Access

CD154 Induces Interleukin-6 Secretion by Kidney Tubular Epithelial Cells under Hypoxic Conditions: Inhibition by Chloroquine

Antoine Dewitte,  Julien Villeneuve,  Sébastien Lepreux,  Marion Bouchecareilh,  Xavier Gauthereau,  Claire Rigothier,  Christian Combe,  Alexandre Ouattara,  Jean Ripoche, 
  • First Published: 31 January 2020
Review Article
Open Access

Predicting Severe Enterovirus 71-Infected Hand, Foot, and Mouth Disease: Cytokines and Chemokines

Weijian Zhang,  Zhigang Huang,  Mingyuan Huang,  Jincheng Zeng, 
  • First Published: 31 January 2020
Review Article
Open Access

Research Progress on the Role of Inflammasomes in Kidney Disease

Kun Chi,  Xiaodong Geng,  Chao Liu,  GuangYan Cai,  Quan Hong, 
  • First Published: 29 January 2020
Review Article
Open Access

Ischemia/Reperfusion Injury: Pathophysiology, Current Clinical Management, and Potential Preventive Approaches

César Daniel Sánchez-Hernández,  Lucero Aidé Torres-Alarcón,  Ariadna González-Cortés,  Alberto N. Peón, 
  • First Published: 29 January 2020
Research Article
Open Access

Analysis of Myocardial Ischemia Parameters after Coronary Artery Bypass Grafting with Minimal Extracorporeal Circulation and a Novel Microplegia versus Off-Pump Coronary Artery Bypass Grafting

Luca Koechlin,  Urs Zenklusen,  Thomas Doebele,  Bejtush Rrahmani,  Brigitta Gahl,  Thibault Schaeffer,  Denis Berdajs,  Friedrich S. Eckstein,  Oliver Reuthebuch, 
  • First Published: 25 January 2020
Research Article
Open Access

Systemic Administration of Calea pinnatifida Inhibits Inflammation Induced by Carrageenan in a Murine Model of Pulmonary Neutrophilia

Bruno Matheus de Campos Facchin,  Julia Salvan da Rosa,  Ana Beatriz Gobbo Luz,  Yeo Jim Kinoshita Moon,  Tamires Cardoso de Lima,  Rosana Casoti,  Maique Weber Biavatti,  Eduardo Monguilhott Dalmarco,  Tânia Silvia Fröde, 
  • First Published: 25 January 2020
Research Article
Open Access

The Role of Angiogenesis Factors in the Formation of Vascular Changes in Scleroderma by Assessment of the Concentrations of VEGF and sVEGFR2 in Blood Serum and Tear Fluid

Arleta Waszczykowska,  Roman Goś,  Elżbieta Waszczykowska,  Bożena Dziankowska-Bartkowiak,  Michał Podgórski,  Piotr Jurowski, 
  • First Published: 24 January 2020
Research Article
Open Access

miR-10a in Peripheral Blood Mononuclear Cells Is a Biomarker for Sepsis and Has Anti-Inflammatory Function

Guoping Zheng,  Guanguan Qiu,  Menghua Ge,  Jianbiao Meng,  Geng Zhang,  Jiangmei Wang,  Ruoqiong Huang,  Qiang Shu,  Jianguo Xu, 
  • First Published: 22 January 2020
Research Article
Open Access

MEG3 Alleviated LPS-Induced Intestinal Injury in Sepsis by Modulating miR-129-5p and Surfactant Protein D

Xianjin Du,  Dan Tian,  Jie Wei,  Chen Yan,  Peng Hu,  Xu Wu,  Wenbin Yang, 
  • First Published: 22 January 2020
Research Article
Open Access

Salvianolic Acid D Alleviates Cerebral Ischemia-Reperfusion Injury by Suppressing the Cytoplasmic Translocation and Release of HMGB1-Triggered NF-κB Activation to Inhibit Inflammatory Response

Wen Zhang,  Junke Song,  Wan Li,  Dewen Kong,  Yu Liang,  Xiaoyue Zhao,  Guanhua Du, 
  • First Published: 22 January 2020
Research Article
Open Access

Resistin Is Increased in Periodontal Cells and Tissues: In Vitro and In Vivo Studies

Andressa V. B. Nogueira,  Marjan Nokhbehsaim,  Sema Tekin,  Rafael S. de Molon,  Luis C. Spolidorio,  Svenja Memmert,  Anna Damanaki,  Andreas Jäger,  Sigrun Eick,  James Deschner,  Joni A. Cirelli, 
  • First Published: 20 January 2020
Research Article
Open Access

Comparison of Inhibitor and Substrate Selectivity between Rodent and Human Vascular Adhesion Protein-1

Ryo Kubota,  Michael J. Reid,  Kuo Lee Lieu,  Mark Orme,  Christine Diamond,  Niklas Tulberg,  Susan H. Henry, 
  • First Published: 20 January 2020
Research Article
Open Access

Gene Expression Profiling of Mediators Associated with the Inflammatory Pathways in the Intestinal Tissue from Patients with Ulcerative Colitis

Gabriela Fonseca Camarillo,  Emilio Iturriaga Goyon,  Rafael Barreto Zuñiga,  Lucero Adriana Salazar Salas,  Ana Elena Peredo Escárcega,  Jesús K. Yamamoto-Furusho, 
  • First Published: 18 January 2020
Research Article
Open Access

IL-4 Receptor-Alpha Signalling of Intestinal Epithelial Cells, Smooth Muscle Cells, and Macrophages Plays a Redundant Role in Oxazolone Colitis

Jennifer Claire Hoving,  Roanne Keeton,  Maxine A. Höft,  Mumin Ozturk,  Patricia Otieno-Odhiambo,  Frank Brombacher, 
  • First Published: 17 January 2020
Research Article
Open Access

New Potential Weapons for Refractory Scleritis in the Era of Targeted Therapy

Claudia Fabiani,  Jurgen Sota,  Maite Sainz-de-la-Maza,  Laura Pelegrín,  Giacomo Emmi,  Giuseppe Lopalco,  Florenzo Iannone,  Lorenzo Vannozzi,  Silvana Guerriero,  Maria Chiara Gelmi,  Donato Rigante,  Gian Marco Tosi,  José Hernández-Rodríguez,  Luca Cantarini, 
  • First Published: 17 January 2020
Research Article
Open Access

lncRNA IGHCγ1 Acts as a ceRNA to Regulate Macrophage Inflammation via the miR-6891-3p/TLR4 Axis in Osteoarthritis

Pengjun Zhang,  Jianmei Sun,  Caihong Liang,  Bingjie Gu,  Yang Xu,  Hongying Lu,  Bo Cao,  Hao Xu, 
  • First Published: 17 January 2020
Research Article
Open Access

Circulating IL-17A Levels in Postmenopausal Women with Primary Hyperparathyroidism

E. Dozio,  E. Passeri,  E. Vianello,  S. Palmieri,  C. Eller-Vainicher,  M. Corsi Romanelli,  S. Corbetta, 
  • First Published: 17 January 2020
Research Article
Open Access

Advanced Glycated apoA-IV Loses Its Ability to Prevent the LPS-Induced Reduction in Cholesterol Efflux-Related Gene Expression in Macrophages

Ligia Shimabukuro Okuda,  Rodrigo Tallada Iborra,  Paula Ramos Pinto,  Ubiratan Fabres Machado,  Maria Lucia Corrêa-Giannella,  Russell Pickford,  Tom Woods,  Margaret Anne Brimble,  Kerry-Anne Rye,  Marisa Passarelli, 
  • First Published: 14 January 2020
Research Article
Open Access

Apolipoprotein A-V Is a Novel Diagnostic and Prognostic Predictor in Pediatric Patients with Sepsis: A Prospective Pilot Study in PICU

Chunxia Wang,  Yun Cui,  Huijie Miao,  Xi Xiong,  Jiaying Dou,  Lujing Shao,  Xiaomeng Tang,  Yucai Zhang, 
  • First Published: 13 January 2020
Review Article
Open Access

Extracellular Vesicles with Possible Roles in Gut Intestinal Tract Homeostasis and IBD

Xin Chang,  Shu-Ling Wang,  Sheng-Bing Zhao,  Yi-Hai Shi,  Peng Pan,  Lun Gu,  Jun Yao,  Zhao-Shen Li,  Yu Bai, 
  • First Published: 13 January 2020
Research Article
Open Access

Toll-Like Receptor-Mediated Cardiac Injury during Experimental Sepsis

Ina Lackner,  Birte Weber,  Shinjini Chakraborty,  Sonja Braumüller,  Markus Huber-Lang,  Florian Gebhard,  Miriam Kalbitz, 
  • First Published: 10 January 2020
Research Article
Open Access

Quartz Dust Exposure Affects NLRP3 Inflammasome Activation and Plasma Levels of IL-18 and IL-1Ra in Iron Foundry Workers

Alexander Hedbrant,  Lena Andersson,  Ing-Liss Bryngelsson,  Daniel Eklund,  Håkan Westberg,  Eva Särndahl,  Alexander Persson, 
  • First Published: 07 January 2020
Research Article
Open Access

Soluble Intercellular Adhesion Molecule- (sICAM-) 1, Thrombospondin-1, and Vinculin for the Identification of Septic Shock Patients Suffering from an Invasive Fungal Infection

Sebastian O. Decker,  Anne Incamps,  Annette Sigl,  Florian Uhle,  Thomas Bruckner,  Alexandra Heininger,  Stefan Zimmermann,  Christophe Hirtz,  Markus A. Weigand,  Thorsten Brenner, 
  • First Published: 07 January 2020
Research Article
Open Access

Psychobiotics Regulate the Anxiety Symptoms in Carriers of Allele A of IL-1β Gene: A Randomized, Placebo-Controlled Clinical Trial

P. Gualtieri,  M. Marchetti,  G. Cioccoloni,  A. De Lorenzo,  L. Romano,  A. Cammarano,  C. Colica,  R. Condò,  L. Di Renzo, 
  • First Published: 07 January 2020