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    2021
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Research Article
Open Access

Intraoperative Use of Topical Retropharyngeal Steroids for Dysphagia after Anterior Cervical Fusion: A Systematic Review and Meta-Analysis

Hang Yu,  Hui Dong,  Binjia Ruan,  Xiaohang Xu,  Yongxiang Wang, 
  • First Published: 31 December 2021
Research Article
Open Access

Relationship between Expression of Plasma lncRNA-HEIH and Prognosis in Patients with Coronary Artery Disease

Zhenying Zhang,  Sushuang Nan,  Xiujuan Duan,  Lizhong Wang,  Xiaojing Sun,  Haiying Zheng, 
  • First Published: 31 December 2021
Research Article
Open Access

lncRNA PCAT14 Is a Diagnostic Marker for Prostate Cancer and Is Associated with Immune Cell Infiltration

Yunkun Yan,  Jianjun Liu,  Zhijian Xu,  Mushi Ye,  Jianchang Li, 
  • First Published: 31 December 2021
Research Article
Open Access

Association of Iris Structural Measurements with Corneal Biomechanics in Myopic Eyes

Lin Fu,  Yufeng Ye,  Xu Jia,  Yunjie Zhang,  Xiaoyu Chen,  Hengli Lian,  Weihua Yang,  Qi Dai, 
  • First Published: 31 December 2021
Research Article
Open Access

Transcription Factors Leading to High Expression of Neuropeptide L1CAM in Brain Metastases from Lung Adenocarcinoma and Clinical Prognostic Analysis

Xu Feng,  Ning Guan,  Enshi Xu,  Ye Miao,  Chenguang Li, 
  • First Published: 30 December 2021
Review Article
Open Access

Role of Biomarkers in the Integrated Management of Melanoma

Piyu Parth Naik, 
  • First Published: 30 December 2021
Research Article
Open Access

Mechanism and Role of the Neuropeptide LGI1 Receptor ADAM23 in Regulating Biomarkers of Ferroptosis and Progression of Esophageal Cancer

Chen Chen,  Jun Zhao,  Jing-ni Liu,  Chenyu Sun, 
  • First Published: 30 December 2021
Research Article
Open Access

CYP1B1-AS1 Is a Novel Biomarker in Glioblastoma by Comprehensive Analysis

Tao Ye,  Lan-lan Li,  Xue-mei Peng,  Qin Li, 
  • First Published: 29 December 2021
Research Article
Open Access

Prognostic Significance of the Combined Score of Plasma Fibrinogen and Neutrophil-Lymphocyte Ratio in Patients with Spontaneous Intracerebral Hemorrhage

Wanchun Yang,  Yunbo Yuan,  Junhong Li,  Yuli Shuai,  Xiang Liao,  Zhiyuan Yu,  Hao Li,  Jun Zheng, 
  • First Published: 29 December 2021
Research Article
Open Access

Identification of Cross-Talk and Pyroptosis-Related Genes Linking Periodontitis and Rheumatoid Arthritis Revealed by Transcriptomic Analysis

Yongbin Jing,  Dong Han,  Chunyang Xi,  Jinglong Yan,  Jinpeng Zhuang, 
  • First Published: 29 December 2021
Research Article
Open Access

Potential Factors of Corneal Endothelial Cells for Progression in Children with Uveitis

Xu Chen,  Yi Shao,  Shi-Nan Wu,  Shan-Bi Zhou, 
  • First Published: 28 December 2021
Research Article
Open Access

Nonalcoholic Fatty Liver Disease-Associated Liver Fibrosis Is Linked with the Severity of Coronary Artery Disease Mediated by Systemic Inflammation

Ling-zi Chen,  Xu-bin Jing,  Chao-fen Wu,  Yi-cheng Zeng,  Yan-chun Xie,  Mu-qing Wang,  Wen-xia Chen,  Xi Hu,  Yan-na Zhou,  Xian-bin Cai, 
  • First Published: 28 December 2021
Research Article
Open Access

Correlation between Serum Fatty Acid Binding Protein 4 (FABP4) Levels and Cardiac Function in Patients with Thalassemia Major

Pandji I. Fianza,  Anita Rahmawati,  Shofura Afifah,  Suhendra Praptama,  Mohammad Ghozali,  Teddy A. Sihite,  Djatnika Setiabudi,  Mas R. A. A. Syamsunarno,  Suthat Fucharoen,  Ramdan Panigoro, 
  • First Published: 27 December 2021
Research Article
Open Access

Outcomes of a Foldable Capsular Vitreous Body Implantation: A Retrospective Study

Xiangzhong Xu,  Huimin Ge,  Jiajun Li,  Weihong Shang,  Yuke Ji,  Weihua Yang,  Keran Li, 
  • First Published: 26 December 2021
Review Article
Open Access

Prognostic Role of Long Noncoding RNAs in Oral Squamous Cell Carcinoma: A Meta-Analysis

Yu Wang,  Peng Wang,  Xin Liu,  Ziran Gao,  Xianbao Cao,  Xilong Zhao, 
  • First Published: 26 December 2021
Research Article
Open Access

High Expression of JMJD4 Is a Potential Diagnostic and Prognostic Marker of Renal Cell Carcinoma

Hao Yan,  Yewei Bao,  Zongming Lin, 
  • First Published: 24 December 2021
Research Article
Open Access

Serum Levels of lncRNA CCHE1 and TCF21 in Patients with Coronary Artery Disease and Their Clinical Significances

Miaomiao Liu,  Ying Zhang,  Xiantong Cao,  Xue Wang, 
  • First Published: 21 December 2021
Research Article
Open Access

MiR-126-HMGB1-HIF-1 Axis Regulates Endothelial Cell Inflammation during Exposure to Hypoxia-Acidosis

Jinxue Liu,  Eileen Wei,  Jianqin Wei,  Wei Zhou,  Keith A. Webster,  Bin Zhang,  Dong Li,  Gaoxing Zhang,  Yidong Wei,  Yusheng Long,  Xiuyu Qi,  Qianhuan Zhang,  Dingli Xu, 
  • First Published: 21 December 2021
Research Article
Open Access

Effects of Long Noncoding RNA HOTAIR Targeting miR-138 on Inflammatory Response and Oxidative Stress in Rat Cardiomyocytes Induced by Hypoxia and Reoxygenation

Guofeng Wang,  Qi Wang,  Weixue Xu, 
  • First Published: 21 December 2021
Research Article
Open Access

Identification of the 7-lncRNA Signature as a Prognostic Biomarker for Acute Myeloid Leukemia

Chun-yu Liu,  Hui-hui Guo,  Hai-xia Li,  Ying Liang,  Cong Tang,  Nan-nan Chen, 
  • First Published: 20 December 2021
Research Article
Open Access

Governor Vessel Moxibustion Therapy Improves Microbiota Structure in Ankylosing Spondylitis Patients

Guodong Sun,  Qingbo Wang,  Shengnan Cao,  Haidong Xu,  Yan Zhao, 
  • First Published: 20 December 2021
Research Article
Open Access

[Retracted] Study on the Effect of MRI in the Diagnosis of Benign and Malignant Thoracic Tumors

Yan Li,  Yangli Sui,  Mingyan Chi,  Jie Zhang,  Lin Guo, 
  • First Published: 20 December 2021

Research Article
Open Access

Apolipoprotein B/A1 Ratio Is Associated with Severity of Coronary Artery Stenosis in CAD Patients but Not in Non-CAD Patients Undergoing Percutaneous Coronary Intervention

Rui Hua,  Yijun Li,  Wenyuan Li,  Zhen Wei,  Zuyi Yuan,  Juan Zhou, 
  • First Published: 18 December 2021
Research Article
Open Access

Plasma S-Adenosylmethionine Is Associated with Lung Injury in COVID-19

Evgeny Vladimirovich Kryukov,  Alexander Vladimirovich Ivanov,  Vladimir Olegovich Karpov,  Valery Vasil’evich Aleksandrin,  Alexander Mikhaylovich Dygai,  Maria Petrovna Kruglova,  Gennady Ivanovich Kostiuchenko,  Sergei Petrovich Kazakov,  Aslan Amirkhanovich Kubatiev, 
  • First Published: 16 December 2021
Research Article
Open Access

miRNA-19b-3p Stimulates Cardiomyocyte Apoptosis Induced by Myocardial Ischemia Reperfusion via Downregulating PTEN

Ke Li,  Xujie Ya,  Xiujuan Duan,  Yang Li,  Xuefeng Lin, 
  • First Published: 16 December 2021
Review Article
Open Access

Was Antiphospholipid Syndrome a Risk Factor of Stroke? A Systemic Review and Meta-Analysis of Cohort Studies

Kai Zhao,  Ping Zhou,  Ling Xu,  Ruili Li,  Jincai Yang,  Qiang Zhang,  Mingfei Yang,  Xiaoxing Wei, 
  • First Published: 16 December 2021
Research Article
Open Access

The Relationship between Red Cell Distribution Width and Residual SYNTAX Scores in ST-Segment Elevation Myocardial Infarction Patients after Percutaneous Coronary Intervention

Yang Ling,  Wei Wang,  Cong Fu,  Qun Fan,  Jichun Liu,  Shengxing Tang, 
  • First Published: 15 December 2021
Research Article
Open Access

The Degree of Plasma Oxidized Low-Density Lipoprotein Level Decrease Is Related to Clinical Outcomes for Patients with Acute Ischemic Stroke

Xiaoli Yang,  Wenbo Sun,  Duanlu Hou,  Tianyao Wang,  Chen Li,  Yufan Luo,  Shufan Zhang,  Liwei Shen,  Wenpeng Liu,  Danhong Wu, 
  • First Published: 14 December 2021
Review Article
Open Access

The Role of HLA in the Association between IgA Deficiency and Celiac Disease

Dimitri Poddighe,  Cristina Capittini, 
  • First Published: 13 December 2021
Research Article
Open Access

Influence of Silica Exposure for Lung Silicosis Rat

Jie Jiao,  Li Li,  Wu Yao,  Weidong Qin,  Changfu Hao,  Lingeng Lu, 
  • First Published: 13 December 2021
Review Article
Open Access

Global Meta-Analysis on the Association between Behcet Syndrome and Polymorphisms from the HLA Class I (A, B, and C) and Class II (DRB1, DQB1, and DPB1) Genes

Cristina Capittini,  Chiara Rebuffi,  Marco Vincenzo Lenti,  Antonio Di Sabatino,  Carmine Tinelli,  Miryam Martinetti,  Annalisa De Silvestri, 
  • First Published: 13 December 2021
Research Article
Open Access

Circulating MicroRNA Expression, Vitamin D, and Hypercortisolism as Predictors of Osteoporosis in Elderly Postmenopausal Women

Hadeel A. Al-Rawaf,  Ahmad H. Alghadir,  Sami A. Gabr, 
  • First Published: 13 December 2021
Research Article
Open Access

Increased Serum Neuropeptide Galanin Level Is a Predictor of Cognitive Dysfunction in Patients with Hip Fracture

Zichao Xue,  Ke Zhang,  Biao Luo,  Long Fan,  Ruizhe Zhao,  Guangliang Hu, 
  • First Published: 10 December 2021
Research Article
Open Access

Comprehensive Analysis to Identify Key Genes Involved in Advanced Atherosclerosis

Tian-ming Huo,  Zhi-wei Wang, 
  • First Published: 10 December 2021
Research Article
Open Access

Crosstalk between Venous Thromboembolism and Periodontal Diseases: A Bioinformatics Analysis

Zheng He,  Qilong Jiang,  Fuping Li,  Mingxiang Chen, 
  • First Published: 10 December 2021
Research Article
Open Access

The Key Genes Underlying Pathophysiology Association between Plaque Instability and Progression of Myocardial Infarction

Yue Zheng,  Yijie Gong,  Yuheng Lang,  Zhenchang Qi,  Xiaomin Hu,  Tong Li, 
  • First Published: 09 December 2021
Research Article
Open Access

CircLDLR Promotes Papillary Thyroid Carcinoma Tumorigenicity by Regulating miR-637/LMO4 Axis

Yuan-ming Jiang,  Wei Liu,  Ling Jiang,  Hongbin Chang, 
  • First Published: 09 December 2021
Research Article
Open Access

A Comparison of GFR Calculated by Cockcroft-Gault vs. MDRD Formula in the Prognostic Assessment of Patients with Acute Pulmonary Embolism

Magdalena Pływaczewska,  David Jiménez,  Mareike Lankeit,  Piotr Pruszczyk,  Maciej Kostrubiec, 
  • First Published: 08 December 2021
Research Article
Open Access

miRNA-576 Alleviates the Malignant Progression of Atherosclerosis through Downregulating KLF5

Jing Wang,  Lihui Zhang,  Ting Wang,  Caige Li,  Lijing Jiao,  Zhansheng Zhao,  Yongjun Li, 
  • First Published: 08 December 2021
Research Article
Open Access

[Retracted] A Comprehensive Bioinformatic Analysis of NOTCH Pathway Involvement in Stomach Adenocarcinoma

Dongyun Xue,  Dong Li,  Cong Dou,  Junshan Li, 
  • First Published: 08 December 2021

Research Article
Open Access

Discovery and Validation of Novel Methylation Markers in Helicobacter pylori-Associated Gastric Cancer

Huan Wang,  Nian-Shuang Li,  Cong He,  Chuan Xie,  Yin Zhu,  Nong-Hua Lu,  Yi Hu, 
  • First Published: 08 December 2021
Research Article
Open Access

MicroRNA-383-5p Regulates Oxidative Stress in Mice with Acute Myocardial Infarction through the AMPK Signaling Pathway via PFKM

Linlin Gao,  Zhongbao Ruan,  Gecai Chen, 
  • First Published: 07 December 2021
Research Article
Open Access

Metabolomic Profiling Identified Serum Metabolite Biomarkers and Related Metabolic Pathways of Colorectal Cancer

Chengjian Zhang,  Shengnan Zhou,  Huijing Chang,  Feng Zhuang,  Yang Shi,  Le Chang,  Wanchao Ai,  Juan Du,  Wei Liu,  Humin Liu,  Xukun Zhou,  Zhong Wang,  Tao Hong, 
  • First Published: 07 December 2021
Research Article
Open Access

Integrative Molecular Analyses of an Individual Transcription Factor-Based Genomic Model for Lung Cancer Prognosis

Rong Yao,  Leilei Zhou,  Zhongying Guo,  Dahong Zhang,  Tiecheng Zhang, 
  • First Published: 07 December 2021
Research Article
Open Access

Cox-2 Antagonizes the Protective Effect of Sevoflurane on Hypoxia/Reoxygenation-Induced Cardiomyocyte Apoptosis through Inhibiting the Akt Pathway

Chunyan Guo,  Lei Zhang,  Yaoxing Gao,  Junzhi Sun,  Lingling Fan,  Yuguang Bai,  Jing Zhang,  Gaowa Naren,  Jiwen Yang,  Libiao Li, 
  • First Published: 07 December 2021
Research Article
Open Access

MicroRNA-146-5p Promotes Pulmonary Artery Endothelial Cell Proliferation under Hypoxic Conditions through Regulating USP3

Wei Zhang,  Yujuan Qi,  Bo Wu, 
  • First Published: 07 December 2021
Research Article
Open Access

Transneuronal Degeneration in the Visual Pathway of Rats following Acute Retinal Ischemia/Reperfusion

Yanyan Fu,  Tu Hu,  Qianyue Zhang,  Shuhan Meng,  Ying Lu,  Aiqun Xiang,  Yewei Yin,  Yuanjun Li,  Jiayu Song,  Dan Wen, 
  • First Published: 07 December 2021
Research Article
Open Access

Septicemic Melioidosis Detection Using Support Vector Machine with Five Immune Cell Types

Ke Xu,  Fang Lian,  Yunfan Quan,  Jun Liu,  Li Yin,  Xuexia Li,  Shen Tian,  Hua Pei,  Qianfeng Xia, 
  • First Published: 06 December 2021
Research Article
Open Access

Early Prediction of Disease Progression in Patients with Severe COVID-19 Using C-Reactive Protein to Albumin Ratio

Yi Li,  Haitao Li,  Chao Song,  Rongli Lu,  Yuhao Zhao,  Fengyu Lin,  Duoduo Han,  Lingli Chen,  Pinhua Pan,  Minhui Dai, 
  • First Published: 03 December 2021
Research Article
Open Access

The Relationship between Body Mass Index, Obesity, and LINE-1 Methylation: A Cross-Sectional Study on Women from Southern Italy

Andrea Maugeri,  Martina Barchitta,  Roberta Magnano San Lio,  Giuliana Favara,  Claudia La Mastra,  Maria Clara La Rosa,  Antonella Agodi, 
  • First Published: 03 December 2021
Research Article
Open Access

Pyroptosis-Related Gene Signature Is a Novel Prognostic Biomarker for Sarcoma Patients

Dalong Wei,  Xiaoling Lan,  Zhiqun Huang,  Qiang Tang,  Zechen Wang,  Yanfei Ma,  Liuzhi Wei,  Qiuju Wei,  Jingjie Zhao,  Jiajia Shen,  Siyuan He,  Jian Song,  Lingzhang Meng,  Qianli Tang, 
  • First Published: 03 December 2021
Research Article
Open Access

Prognostic Value of lncRNA PVT1 for Patients with Gastric Cancer: A Meta-Analysis

Jinyong Hao,  Bo Yuan,  Yani Gou,  Jichun Ma,  Xiaojun Huang, 
  • First Published: 02 December 2021
Research Article
Open Access

Identification of MATN3 as a Novel Prognostic Biomarker for Gastric Cancer through Comprehensive TCGA and GEO Data Mining

Pan Wang,  Wei-sheng Xiao,  Yue-hua Li,  Xiao-ping Wu,  Hong-bo Zhu,  Ye-ru Tan, 
  • First Published: 02 December 2021
Research Article
Open Access

Protective Effect of Fasudil on Hydrogen Peroxide-Induced Oxidative Stress Injury of H9C2 Cardiomyocytes

Yu Zhang,  Shanxin Liu,  Xiaochun Li,  Jian Ye, 
  • First Published: 01 December 2021
Research Article
Open Access

[Retracted] To Explore the Haemostatic Effect of Compression Haemostasis Using an Ultrasonic Probe under the Guidance of Ultrasound after Radial Artery Puncture

Xianwei Jin,  Qiaoling Weng,  Jia Min, 
  • First Published: 01 December 2021

Research Article
Open Access

Efficacy of Human Umbilical Cord Blood-Mononuclear Cell Transplantation for MSA Treatment and Its Effects on Changes in T-Cell Subsets in Peripheral Blood and Inflammatory Factors

Haiyan Yu,  Xiaoling Yuan,  Min Zhao,  Weifei Wang,  Dianrong Gong, 
  • First Published: 01 December 2021
Research Article
Open Access

Regulatory Mechanism of LINC00152 on Aggravating Heart Failure through Triggering Fibrosis in an Infarcted Myocardium

Lizhong Song,  Xiujuan Duan,  Xiaojuan Zeng,  Xinglian Duan,  Li Li, 
  • First Published: 01 December 2021
Research Article
Open Access

Tanshinone IIA Improves Ventricular Remodeling following Cardiac Infarction by Regulating miR-205-3p

Peng Qiao,  Jie Xu,  Xueni Liu,  Xuehan Li, 
  • First Published: 29 November 2021
Research Article
Open Access

Identification of KLF6/PSGs and NPY-Related USF2/CEACAM Transcriptional Regulatory Networks via Spinal Cord Bulk and Single-Cell RNA-Seq Analysis

Xinbing Liu,  Wei Gao,  Wei Liu, 
  • First Published: 29 November 2021
Research Article
Open Access

miR-29a-5p Alleviates Traumatic Brain Injury- (TBI-) Induced Permeability Disruption via Regulating NLRP3 Pathway

Aijun Zhang,  Youming Lu,  Lei Yuan,  Pengqi Zhang,  Dongdong Zou,  Fance Wei,  Xin Chen, 
  • First Published: 28 November 2021
Research Article
Open Access

Expression of ANGPTL4 in Nucleus Pulposus Tissues Is Associated with Intervertebral Disc Degeneration

Fan-jie Liu,  Liang-yu Xie,  Hua-zhong Li,  Sheng-nan Cao,  Yuan-zhen Chen,  Bin-Shi,  Dan-dan Wang, 
  • First Published: 28 November 2021
Research Article
Open Access

USP1 Promotes GC Metastasis via Stabilizing ID2

Nuoya Li,  Lei Wu,  Xingye Zuo,  Huilong Luo,  Yanling Sheng,  Jinlong Yan, 
  • First Published: 27 November 2021
Research Article
Open Access

Identification of SOX6 and SOX12 as Prognostic Biomarkers for Clear Cell Renal Cell Carcinoma: A Retrospective Study Based on TCGA Database

Xiao Lyu,  Xi Zhang,  Li-bin Sun,  Xiao-ming Cao,  Xu-hui Zhang, 
  • First Published: 26 November 2021
Research Article
Open Access

N-Acetylcysteine Slows Down Cardiac Pathological Remodeling by Inhibiting Cardiac Fibroblast Proliferation and Collagen Synthesis

Jin Zhou,  Jing Xu,  Shan Sun,  Mengyuan Guo,  Peng Li,  Aijuan Cheng, 
  • First Published: 26 November 2021
Research Article
Open Access

The Role of Conjunctival Microvasculation Combined with Echocardiography in Evaluating Pulmonary Arterial Hypertension in Systemic Lupus Erythematosus

Jiangbiao Xiong,  Shujiao Yu,  Ren Liu,  Xia Fang,  Rui Wu, 
  • First Published: 26 November 2021
Research Article
Open Access

A Novel Ferroptosis-Related Gene Risk Signature for Predicting Prognosis and Immunotherapy Response in Gastric Cancer

Shi-jin Liu,  Ya-bing Yang,  Jia-xin Zhou,  Yu-jian Lin,  Yun-long Pan,  Jing-hua Pan, 
  • First Published: 26 November 2021
Research Article
Open Access

miR-190-5p Alleviates Myocardial Ischemia-Reperfusion Injury by Targeting PHLPP1

Yangxue Li,  Zhibo Li,  Jiangen Liu,  Yihang Liu,  Guobin Miao, 
  • First Published: 25 November 2021
Research Article
Open Access

RRM2 Improves Cardiomyocyte Proliferation after Myocardial Ischemia Reperfusion Injury through the Hippo-YAP Pathway

Huamin Yu,  Haiyan Tang,  Chaochao Deng,  Qing Lin,  Peng Yu,  Shaowen Chen,  Jingming Ruan, 
  • First Published: 25 November 2021
Research Article
Open Access

Comprehensive Analysis of the Immune and Prognostic Implication of MMP14 in Lung Cancer

Chun-long Zheng,  Qiang Lu,  Nian Zhang,  Peng-yu Jing,  Ji-peng Zhang,  Wu-ping Wang,  Gui-zhen Li, 
  • First Published: 24 November 2021
Research Article
Open Access

Identification of a Novel Ferroptosis-Related Gene Prediction Model for Clinical Prognosis and Immunotherapy of Colorectal Cancer

Ya-bing Yang,  Jia-xin Zhou,  Sheng-hui Qiu,  Jia-shuai He,  Jing-hua Pan,  Yun-long Pan, 
  • First Published: 24 November 2021
Research Article
Open Access

Upregulated Transcription Factor PITX1 Predicts Poor Prognosis in Kidney Renal Clear Cell Carcinoma-Based Bioinformatic Analysis and Experimental Verification

Yinglang Zhang,  Zhe Zhang,  Wei Zhang,  Hailong Hu,  Guochang Bao, 
  • First Published: 23 November 2021
Research Article
Open Access

FOXC2 Alleviates Myocardial Ischemia-Reperfusion Injury in Rats through Regulating Nrf2/HO-1 Signaling Pathway

Rui Wang,  Yonggang Wu,  Shoutao Jiang, 
  • First Published: 23 November 2021
Research Article
Open Access

MALAT-1 Expression Correlates with Prognosis in Non-Small-Cell Lung Carcinoma: A Systematic Review and Meta-analysis

Ran Ran,  Jian-wei Jin,  Wei-ping Zhang, 
  • First Published: 23 November 2021
Research Article
Open Access

Integrative Bioinformatics Analysis Reveals That Infarct-Mediated Overexpression of Potential miR-662/CREB1 Pathway-Induced Neuropeptide VIP Is Associated with the Risk of Atrial Fibrillation: A Correlation Analysis between Myocardial Electrophysiology and Neuroendocrine

Pengpai Zhang,  Bo Liu, 
  • First Published: 22 November 2021
Research Article
Open Access

A Novel Predictive Nomogram including Serum Lipoprotein a Level for Nonsentinel Lymph Node Metastases in Chinese Breast Cancer Patients with Positive Sentinel Lymph Node Metastases

Zeng Fang,  Ruizhi Wang,  Ciqiu Yang,  Dong Wang,  Wanna Chen,  Bo Lin,  Dongsheng Gong,  Songqi Li,  Jiadong Liang,  Xiaoli Liang,  Chunxian Zeng,  Jie Li,  Kun Wang,  Weiming Lv, 
  • First Published: 22 November 2021
Research Article
Open Access

A Novel Ferroptosis-Related Gene Signature to Predict Prognosis in Patients with Head and Neck Squamous Cell Carcinoma

Li Xu,  Ying-ying Li,  Yang-chun Zhang,  Yong-xu Wu,  Dan-dan Guo,  Dan Long,  Zhao-hui Liu, 
  • First Published: 22 November 2021
Research Article
Open Access

The Role of Fecal Fusobacterium nucleatum and pks+ Escherichia coli as Early Diagnostic Markers of Colorectal Cancer

Kaixi Liu,  Xinran Yang,  Mi Zeng,  Yumeng Yuan,  Jianhong Sun,  Ping He,  Jiayu Sun,  Qingdong Xie,  Xiaolan Chang,  Suwei Zhang,  Xiang Chen,  Leshan Cai,  Yanxuan Xie,  Xiaoyang Jiao, 
  • First Published: 22 November 2021
Research Article
Open Access

Derivation of a Novel CIHI in Patients with Lung Adenocarcinoma for Estimating Tumor Microenvironment and Clinical Prognosis

Liang Zhou,  Guangyan Xu,  Li Wang,  Jianyong Zhang,  Weimin Li, 
  • First Published: 22 November 2021
Research Article
Open Access

Effects of Upregulation of TNFAIP3 on Diabetic Neuropathic Pain in Mice

Yang Liu,  Jinhe Li,  Hongbo Yao,  Meng Zhang,  Jie Lian,  Haiyan Zhang,  Keshuang Zhang,  Danyang Liu,  Jiwei Chen,  Yuejing Wang,  Yin Gao, 
  • First Published: 22 November 2021
Research Article
Open Access

IL-38 and IL-36 Target Autophagy for Regulating Synoviocyte Proliferation, Migration, and Invasion in Rheumatoid Arthritis

Zhe Hao,  Yi Liu, 
  • First Published: 20 November 2021
Research Article
Open Access

Prognostic and Immunological Significance of CXCR2 in Ovarian Cancer: A Promising Target for Survival Outcome and Immunotherapeutic Response Assessment

Haizhou Ji,  Mi Ren,  Tongyu Liu,  Yang Sun, 
  • First Published: 19 November 2021
Research Article
Open Access

The Prognostic Value of the Albumin to Gamma-Glutamyltransferase Ratio in Patients with Hepatocellular Carcinoma Undergoing Radiofrequency Ablation

Wenfeng Liu,  Feng Zhang,  Bing Quan,  Miao Li,  Shenxin Lu,  Jinghuan Li,  Rongxin Chen,  Xin Yin, 
  • First Published: 19 November 2021
Research Article
Open Access

Association between Iris Biological Features and Corneal Biomechanics in Myopic Eyes

Lin Fu,  Qi Dai,  Pengzhi Zhu,  Xu Jia,  Fangjun Bao,  Xiaoyu Chen,  Yana Fu,  Hengli Lian,  Weihua Yang,  Yufeng Ye, 
  • First Published: 18 November 2021
Research Article
Open Access

Machine Learning Classification of Mild Traumatic Brain Injury Using Whole-Brain Functional Activity: A Radiomics Analysis

Xiaoping Luo,  Dezhao Lin,  Shengwei Xia,  Dongyu Wang,  Xinmang Weng,  Wenming Huang,  Hongda Ye, 
  • First Published: 18 November 2021
Research Article
Open Access

Construction and Comprehensive Analysis of a Stratification System Based on AGTRAP in Patients with Hepatocellular Carcinoma

Li Wang,  Wenjun Zhang,  Tao Yang,  Le He,  Yunmei Liao,  Jiaxi Lu, 
  • First Published: 17 November 2021
Research Article
Open Access

NEUT-SFL in Patients with COVID-ARDS: A Novel Biomarker for Thrombotic Events?

Laure Stiel,  Yannick Rabouel,  Agathe Debliquis,  Valentin Pointurier,  Joy Mootien,  Khaldoun Kuteifan, 
  • First Published: 17 November 2021
Research Article
Open Access

Cyclophosphamide Attenuates Fibrosis in Lupus Nephritis by Regulating Mesangial Cell Cycle Progression

Yuehong Ma,  Ling Fang,  Rui Zhang,  Peng Zhao,  Yafeng Li,  Rongshan Li, 
  • First Published: 15 November 2021
Review Article
Open Access

Histone Deacetylase Inhibitors: A Promising Therapeutic Alternative for Endometrial Carcinoma

Iason Psilopatis,  Alexandros Pergaris,  Constantinos Giaginis,  Stamatios Theocharis, 
  • First Published: 12 November 2021
Research Article
Open Access

Elevated Serum Neuropeptide FF Levels Are Associated with Cognitive Decline in Patients with Spinal Cord Injury

Shifei Sun,  Shilong Sun,  Yan Meng,  Bin Shi,  Yuanzhen Chen, 
  • First Published: 11 November 2021
Research Article
Open Access

Development and Verification of an Immune-Based Gene Signature for Risk Stratification and Immunotherapeutic Efficacy Assessment in Gastric Cancer

Feng Qiu,  Yumei Zhu,  Yafeng Shi,  Jingjing Ji,  Yingchao Jin, 
  • First Published: 11 November 2021
Research Article
Open Access

PKM2 Is a Potential Diagnostic and Therapeutic Target for Retinitis Pigmentosa

Peiwen Zhu,  Qian Yang,  Gang Li,  Qing Chang, 
  • First Published: 11 November 2021
Research Article
Open Access

mtDNA in the Pathogenesis of Cardiovascular Diseases

Lili Wang,  Qianhui Zhang,  Kexin Yuan,  Jing Yuan, 
  • First Published: 09 November 2021
Research Article
Open Access

The Ocular Surface Characteristics in Prostate Cancer Patients Treated with Androgen Deprivation Therapy

Weina Li,  Xiaofeng Li,  Feilun Cui,  Zhipeng Xu,  Nuo Dong,  Cheng Li, 
  • First Published: 09 November 2021
Research Article
Open Access

Comprehensive Analysis of the Immune Implication of TEX41 in Skin Cutaneous Melanoma

Zhi-yong Chen,  Jie-qing Huang,  Yu Zhu,  Yong-song Chen,  Xue-feng Yu, 
  • First Published: 09 November 2021
Research Article
Open Access

Characterization of Cancer Stem Cell Characteristics and Development of a Prognostic Stemness Index Cell-Related Signature in Oral Squamous Cell Carcinoma

Jin Feng,  Yunxia Li,  Ning Wen, 
  • First Published: 09 November 2021
Research Article
Open Access

Systematic Analysis Uncovers Associations of PGK1 with Prognosis and Immunological Characteristics in Breast Cancer

Liangdong Li,  Yang Bai,  Yang Gao,  Deheng Li,  Lei Chen,  Changshuai Zhou,  Mingtao Feng,  Xin Chen,  Wei Jin,  Yiqun Cao, 
  • First Published: 08 November 2021
Research Article
Open Access

piRNA-31115 Promotes Cell Proliferation and Invasion via PI3K/AKT Pathway in Clear Cell Renal Carcinoma

Xinghua Du,  Haomin Li,  Xuexia Xie,  Liping Shi,  Fan Wu,  Guoliang Li,  Caiyong Lai,  Baoli Heng, 
  • First Published: 08 November 2021

Research Article
Open Access

STAT1-Induced Upregulation lncRNA LINC00958 Accelerates the Epithelial Ovarian Cancer Tumorigenesis by Regulating Wnt/β-Catenin Signaling

Min Xie,  Qi Fu,  Pin-pin Wang,  Yu-lan Cui, 
  • First Published: 08 November 2021
Research Article
Open Access

Aspirin Exerts Neuroprotective Effects by Reversing Lipopolysaccharide-Induced Secondary Brain Injury and Inhibiting Matrix Metalloproteinase-3 Gene Expression

Depeng Feng,  Dezhe Chen,  Tuanzhi Chen,  Xiaoqian Sun, 
  • First Published: 08 November 2021
Research Article
Open Access

BDNF Acts as a Prognostic Factor Associated with Tumor-Infiltrating Th2 Cells in Pancreatic Adenocarcinoma

Yanan Zhu,  Cangang Zhang,  Dongyu Zhao,  Wenhua Li,  Zhe Zhao,  Shukun Yao,  Dongyan Zhao, 
  • First Published: 05 November 2021
Research Article
Open Access

The Upregulation of PLXDC2 Correlates with Immune Microenvironment Characteristics and Predicts Prognosis in Gastric Cancer

Yang Li,  Jia-qi Li,  Hai-ping Jiang,  Xin Li, 
  • First Published: 05 November 2021
Research Article
Open Access

Construction of the circRNA-miRNA-mRNA Regulatory Network of an Abdominal Aortic Aneurysm to Explore Its Potential Pathogenesis

Hao Zhang,  Ce Bian,  Simei Tu,  Fanxing Yin,  Panpan Guo,  Jian Zhang,  Yihao Wu,  Yuhan Yin,  Jiahui Guo,  Yanshuo Han, 
  • First Published: 05 November 2021
Research Article
Open Access

Identification of Biomarkers Related to Immune Cell Infiltration with Gene Coexpression Network in Myocardial Infarction

Lei Zhang,  Qiqi Wang,  Xudong Xie, 
  • First Published: 05 November 2021
Research Article
Open Access

DNAJC3-AS1 Is Associated with Proliferation, Metastasis, and Poor Prognosis of Breast Cancer

Yi Zhang,  Jing-jing Li,  Bo Luo,  Xiao-fei Guo,  Jian-xin Liu,  Shun-shi Yang, 
  • First Published: 03 November 2021
Research Article
Open Access

Associations of Perilipin 3 with Insulin Resistance in Arab Adults with Type 2 Diabetes

Amani Alghamdi,  Dalal Z. Alhotti,  Shaun Sabico,  Omar S. Al-Attas,  Nasser M. Al-Daghri, 
  • First Published: 02 November 2021
Research Article
Open Access

Programmed Cell Death Protein Ligand 2 Is a Potential Biomarker That Predicts the Efficacy of Immunotherapy

Aoyun Wang,  Han Chu,  Zheng Jin,  Qingzhu Jia,  Bo Zhu, 
  • First Published: 31 October 2021
Research Article
Open Access

The Roles of Liver Inflammation and the Insulin Signaling Pathway in PM2.5 Instillation-Induced Insulin Resistance in Wistar Rats

Zhihua Zhang,  Shujun Hu,  Ping Fan,  Ling Li,  Shanshan Feng,  Huabing Xiao,  Lingyan Zhu, 
  • First Published: 29 October 2021
Research Article
Open Access

Comprehensive Analysis of N6-Methyladenosine-Related lncRNA Signature for Predicting Prognosis and Immune Cell Infiltration in Patients with Colorectal Cancer

Zhan Zhao,  Ya-bing Yang,  Xin-yuan Li,  Xu-Guang Li,  Xiao-dong Chu,  Zheng-bin Lin,  Yi-ran Zhang,  Yan-guan Guo,  Hui Ding,  Yun-long Pan,  Liang Wang,  Jing-hua Pan, 
  • First Published: 28 October 2021
Research Article
Open Access

Serum Calcium Level Combined with Platelet Count May Be Useful Indicators for Assisted Diagnosis of Extremity Posttraumatic Osteomyelitis: A Comparative Analysis

Guan-qiao Liu,  Nan Jiang,  Yan-jun Hu,  Qing-rong Lin,  Lei Wang,  Bin Yu, 
  • First Published: 28 October 2021
Research Article
Open Access

Ral GEF with the PH Domain and SH3 Binding Motif 1 Regulated by Splicing Factor Junction Plakoglobin and Pyrimidine Metabolism Are Prognostic in Uterine Carcinosarcoma

Hongjun Guo,  Siqiao Wang,  Aiqing Xie,  Wenhuizi Sun,  Chenlu Wei,  Shuyuan Xian,  Huabin Yin,  Mingxiao Li,  Hanlin Sun,  Hong Li,  Tong Meng,  Jie Zhang,  Zongqiang Huang, 
  • First Published: 28 October 2021
Research Article
Open Access

Pan-Cancer Analysis Reveals FH as a Potential Prognostic and Immunological Biomarker in Lung Adenocarcinoma

Heng Zhang,  Qiang Ju,  Jing Ji,  Yanjie Zhao, 
  • First Published: 26 October 2021
Research Article
Open Access

Effect of Bloodletting at Shaoshang and Shangyang Acupuncture Points on Outcome and Prognosis of Severe Community-Acquired Pneumonia in the Elderly

Yuefeng Fu,  Zhe Yang,  Yangping Cai,  Hongshuan Liu,  Shuo Li,  Nan Kou,  Jingqin Wu,  Qing Zhang, 
  • First Published: 26 October 2021
Research Article
Open Access

Perioperative Circulating Tumor Cells (CTCs), MCTCs, and CTC-White Blood Cells Detected by a Size-Based Platform Predict Prognosis in Renal Cell Carcinoma

Zhenlong Wang,  Peng Zhang,  Yue Chong,  Yuquan Xue,  Xiaojie Yang,  Hecheng Li,  Li Wang,  Yaping Zhang,  Qi Chen,  Zhaolun Li,  Li Xue,  HongLiang Li,  Tie Chong, 
  • First Published: 25 October 2021
Research Article
Open Access

The Metabolome of Carbapenem-Resistant Klebsiella pneumoniae Infection in Plasma

Zhongwei Wen,  Mei Liu,  Dong Rui,  Xiaoxiao Liao,  Rui Su,  Zhenming Tang,  Zhineng Wen,  Zhougui Ling, 
  • First Published: 22 October 2021
Research Article
Open Access

High DND1 Level Indicates a Poor Prognostic Factor in Prostate Cancer

Gongquan Xu,  Xiaotong Yang,  Chunchang Li,  Fan Wang,  Jing Cui,  Bin Li,  Huiyuan Xiao,  Kunlong Tang,  Zhe Cui, 
  • First Published: 22 October 2021
Research Article
Open Access

Circulating microRNAs and Molecular Oxidative Stress in Older Adults with Neuroprogression Disorders

Hadeel A. Al-Rawaf,  Ahmad H. Alghadir,  Sami A. Gabr, 
  • First Published: 22 October 2021
Research Article
Open Access

Association of Myocardial Enzyme Abnormality with Clinical Outcomes of Patients with COVID-19: A Retrospective Study

Qilin Zhang,  Ziming Zheng,  Yu Zhang, 
  • First Published: 22 October 2021
Research Article
Open Access

Neuropeptides as the Shared Genetic Crosstalks Linking Periodontitis and Major Depression Disorder

Changsheng Sun,  Jiatong Han,  Yixin Bai,  Zhaowei Zhong,  Yingtao Song,  Yu Sun, 
  • First Published: 21 October 2021
Research Article
Open Access

Identification and Validation of a Proliferation-Associated Score Model Predicting Survival in Lung Adenocarcinomas

Yunyi Bian,  Qihai Sui,  Guoshu Bi,  Yuansheng Zheng,  Mengnan Zhao,  Guangyu Yao,  Liang Xue,  Yi Zhang,  Hong Fan, 
  • First Published: 21 October 2021
Research Article
Open Access

Derivation and Comprehensive Analysis of Aging Patterns in Patients with Bladder Cancer

Bin Wang,  Fachun Tong,  Chengxi Zhai,  Long Wang,  Yunzan Liu,  Jian Wang, 
  • First Published: 21 October 2021
Research Article
Open Access

A Cell Cycle Progression-Derived Gene Signature to Predict Prognosis and Therapeutic Response in Hepatocellular Carcinoma

Yongfeng Hui,  Junzhi Leng,  Dong Jin,  Di Liu,  Genwang Wang,  Qi Wang,  Yanyang Wang, 
  • First Published: 21 October 2021
Research Article
Open Access

Identification of Epithelial-Mesenchymal Transition- (EMT-) Related LncRNA for Prognostic Prediction and Risk Stratification in Esophageal Squamous Cell Carcinoma

Peipei Wang,  Yueyun Chen,  Yue Zheng,  Yang Fu,  Zhenyu Ding, 
  • First Published: 19 October 2021
Research Article
Open Access

Urinary Matrix Metalloproteinase-9 and Nephrin in Idiopathic Membranous Nephropathy: A Cross-Sectional Study

Akankwasa Gilbert,  An Changjuan,  Cheng Guixue,  Liu Jianhua,  Qin Xiaosong, 
  • First Published: 18 October 2021
Research Article
Open Access

[Retracted] Study on the Killing Effect of γδT Cells Activated by Rukangyin on Breast Cancer MDA-MB-231 Cells

Zaiwang Chen,  Yujuan Zhao,  Xiangqi Li,  Keqiang Wang, 
  • First Published: 15 October 2021

Research Article
Open Access

Diagnostic, Prognostic, Predictive, and Monitoring Role of Neutrophil CD11b and Monocyte CD14 in Neonatal Sepsis

Heba E. Hashem,  Zakaria H. Ibrahim,  Wafaa O. Ahmed, 
  • First Published: 14 October 2021
Research Article
Open Access

Collagen Family Genes Associated with Risk of Recurrence after Radiation Therapy for Vestibular Schwannoma and Pan-Cancer Analysis

Qingyuan Shi,  Xiaojun Yan,  Jiyun Wang,  Xiangbao Zhang, 
  • First Published: 13 October 2021
Research Article
Open Access

Whole Blood Transcriptome Analysis Reveals the Correlation between Specific Immune Cells and Septicemic Melioidosis

Ke Xu,  Dahua Xu,  Hua Pei,  Yunfan Quan,  Jun Liu,  Li Yin,  Xuexia Li,  ShenTian,  Kongning Li,  Qianfeng Xia, 
  • First Published: 13 October 2021
Research Article
Open Access

A Retrospective Cohort Study on the Association between Red Cell Distribution Width and All-Cause Mortality of Patients with Cholecystitis at ICU Admission

Yihua Dong,  Yu Pan,  Wei Zhou,  Yanhuo Xia,  Jingye Pan, 
  • First Published: 13 October 2021
Research Article
Open Access

Optical Coherence Tomography Angiography Characteristics Serve as Retinal Vein Occlusion Therapeutic Biomarkers for Dexamethasone Intravitreal Implant

Ke Shi,  Xiaodong Sun,  Jingfa Zhang, 
  • First Published: 13 October 2021
Research Article
Open Access

Tanshinone IIA and Astragaloside IV Inhibit miR-223/JAK2/STAT1 Signalling Pathway to Alleviate Lipopolysaccharide-Induced Damage in Nucleus Pulposus Cells

Xiaoxun Du,  Xiaoying Wang,  Kaiying Cui,  Yungang Chen,  Chao Zhang,  Kang Yao,  Yanke Hao,  Yuanzhen Chen, 
  • First Published: 12 October 2021
Research Article
Open Access

Cu(II) Coordination Polymer Inhibits Liver Cancer Development via Targeting BCL-2 Protein and Activating Apoptotic Pathway

Jing Zhou,  Xiaowen Peng,  Xuejiao Li,  Xiaoyu Kong, 
  • First Published: 12 October 2021
Research Article
Open Access

Therapeutic Effects of 25-Hydroxyvitamin D on the Pathological Process of Benign Prostatic Hyperplasia: An In Vitro Evidence

Yanbo Chen,  Hui Xu,  Chong Liu,  Meng Gu,  Qi Chen,  Ming Zhan,  Zhong Wang, 
  • First Published: 11 October 2021
Research Article
Open Access

Meta-Analysis of miRNA Variants Associated with Susceptibility to Autoimmune Disease

Jun Zhang,  Handan Tan,  Qingfeng Cao,  Guannan Su,  Peizeng Yang, 
  • First Published: 08 October 2021
Research Article
Open Access

Value of the Neutrophil-Lymphocyte Ratio in Predicting COVID-19 Severity: A Meta-analysis

Ying Wang,  Jingyi Zhao,  Lan Yang,  Junhui Hu,  Yinhui Yao, 
  • First Published: 08 October 2021
Research Article
Open Access

Complementary Transcriptomic and Proteomic Analysis in the Substantia Nigra of Parkinson’s Disease

Bao-hua Dong,  Zhao-qing Niu,  Jing-tao Zhang,  Yi-jing Zhou,  Fan-mei Meng,  Ai-qin Dong, 
  • First Published: 07 October 2021
Research Article
Open Access

Recanalization Treatment of Acute Ischemic Stroke Caused by Large-Artery Occlusion in the Elderly: A Comparative Analysis of “the Elderly” and “the Very Elderly”

Qi Wang,  Yi-Qun Zhang,  Han-Cheng Qiu,  Yin-Dan Yao,  Ao-Fei Liu,  Chen Li,  Wei-Jian Jiang, 
  • First Published: 06 October 2021
Research Article
Open Access

Predictive Value of Gut Microbiome for Cognitive Impairment in Patients with Hypertension

Shourong Lu,  Lin Shao,  Yunyun Zhang,  Ying Yang,  Zhuo Wang,  Bingshan Zhang,  Jie Yu,  Qiao Xu,  Shuqiang Wang,  Xiaorong Chen,  Zhiming Yu,  Yilin Ren,  Kan Hong, 
  • First Published: 06 October 2021
Research Article
Open Access

The Rise of IGFBP4 in People with Obstructive Sleep Apnea and Multilevel Sleep Surgery Recovers Its Basal Levels

Abdulmohsen Alterki,  Eman Al Shawaf,  Irina Al-Khairi,  Preethi Cherian,  Devarajan Sriraman,  Maha Hammad,  Thangavel A. Thanaraj,  Mahmoud A. K. Ebrahim,  Fahd Al-Mulla,  Mohamed Abu-Farha,  Jehad Abubaker, 
  • First Published: 04 October 2021
Research Article
Open Access

Analyzing mRNAsi-Related Genes Identifies Novel Prognostic Markers and Potential Drug Combination for Patients with Basal Breast Cancer

Kai Huang,  Yu Wu,  YunQing Xie,  LiYing Huang,  Hong Liu, 
  • First Published: 04 October 2021
Research Article
Open Access

Genetic Polymorphisms of IFNG, IFNGR1, and Androgen Receptor and Chronic Prostatitis/Chronic Pelvic Pain Syndrome in a Chinese Han Population

Lei Chen,  Junyi Chen,  Fan Mo,  Zichen Bian,  Chen Jin,  Xianguo Chen,  Chaozhao Liang, 
  • First Published: 04 October 2021
Research Article
Open Access

The Prognostic Value of Serum Uric Acid in Hospitalized Patients with Acute Cerebral Infarction

Bangjian Liu,  Yongchao Pan,  Li Cao,  Jiajun Yang, 
  • First Published: 30 September 2021
Research Article
Open Access

Exploring the Extracellular Vesicle MicroRNA Expression Repertoire in Patients with Rheumatoid Arthritis and Ankylosing Spondylitis Treated with TNF Inhibitors

Joanna Wielińska,  Rachel E. Crossland,  Piotr Łacina,  Jerzy Świerkot,  Bartosz Bugaj,  Anne M. Dickinson,  Katarzyna Bogunia-Kubik, 
  • First Published: 30 September 2021
Research Article
Open Access

H19 Overexpression Improved Efficacy of Mesenchymal Stem Cells in Ulcerative Colitis by Modulating the miR-141/ICAM-1 and miR-139/CXCR4 Axes

Ming-li Zhao,  Tao Chen,  Teng-hui Zhang,  Feng Tian,  Xiao Wan, 
  • First Published: 29 September 2021
Research Article
Open Access

Pericytes of Indirect Contact Coculture Decrease Integrity of Inner Blood-Retina Barrier Model In Vitro by Upgrading MMP-2/9 Activity

Tianye Yang,  Liang Guo,  Yuan Fang,  Mingli Liang,  Yongzheng Zheng,  Mingdong Pan,  Chun Meng,  Guanghui Liu, 
  • First Published: 29 September 2021
Research Article
Open Access

A Pan-Cancer Analysis of SLC12A5 Reveals Its Correlations with Tumor Immunity

Yi Jiang,  Hong-li Liao,  Li-ya Chen, 
  • First Published: 29 September 2021
Research Article
Open Access

Effect of ORF7 of SARS-CoV-2 on the Chemotaxis of Monocytes and Neutrophils In Vitro

Gang Wang,  Jun Guan,  Guojun Li,  Fengtian Wu,  Qin Yang,  Chunhong Huang,  Junwei Shao,  Lichen Xu,  Zixuan Guo,  Qihui Zhou,  Haihong Zhu,  Zhi Chen, 
  • First Published: 28 September 2021
Research Article
Open Access

Association between Plasma Homocysteine Concentrations and the First Ischemic Stroke in Hypertensive Patients with Obstructive Sleep Apnea: A 7-Year Retrospective Cohort Study from China

Nanfang Li,  Xintian Cai,  Qing Zhu,  Xiaoguang Yao,  Mengyue Lin,  Lin Gan,  Le Sun,  Na Yue,  Yingli Ren,  Jing Hong,  Yue Ma,  Run Wang,  Jina Yili,  Qin Luo, 
  • First Published: 28 September 2021
Research Article
Open Access

Association of Preoperative Serum Levels of CEA and CA15-3 with Molecular Subtypes of Breast Cancer

Wenjing Zhao,  Xiaoyan Li,  Wenqing Wang,  Bing Chen,  Lijuan Wang,  Ning Zhang,  Zhe Wang,  Qifeng Yang, 
  • First Published: 28 September 2021
Research Article
Open Access

E2F1-Induced lncRNA BAIAP2-AS1 Overexpression Contributes to the Malignant Progression of Hepatocellular Carcinoma via miR-361-3p/SOX4 Axis

Yan Yang,  Hong Ge,  De-qing Li,  Ai-xia Xu, 
  • First Published: 26 September 2021
Research Article
Open Access

OATP1B1 Plays an Important Role in the Transport and Treatment Efficacy of Sorafenib in Hepatocellular Carcinoma

Jinhua Wen,  Menghua Zhao, 
  • First Published: 26 September 2021
Research Article
Open Access

lncRNA LINC00355 Acts as a Novel Biomarker and Promotes Glioma Biological Activities via the Regulation of miR-1225/FNDC3B

Zhen-yong Qi,  Li-li Wang,  Xu-liang Qu, 
  • First Published: 24 September 2021
Research Article
Open Access

Epigenetic Silencing of SOX15 Is Controlled by miRNAs rather than Methylation in Papillary Thyroid Cancer

Ahmet Ozaydin,  Aysegul Soysal,  Betul Seyhan,  Soykan Arikan,  Nejat Dalay,  Nur Buyru, 
  • First Published: 24 September 2021
Research Article
Open Access

The Effect of Renalase rs2576178 and rs10887800 Polymorphisms on Ischemic Stroke Susceptibility in Young Patients (<50 Years): A Case-Control Study and In Silico Analysis

Nourollah Ramroodi,  Azar Khorrami,  Seyed Mehdi Hashemi,  Mahnaz Rezaei,  Hossein Shahraki-ghadim,  Saeedeh Salimi, 
  • First Published: 23 September 2021
Research Article
Open Access

Network Pharmacology Reveals That Resveratrol Can Alleviate COVID-19-Related Hyperinflammation

Zijian Xiao,  Qing Ye,  Xiaomei Duan,  Tao Xiang, 
  • First Published: 23 September 2021
Research Article
Open Access

Integrated Analysis of lncRNA-Associated ceRNA Network Identifies Two lncRNA Signatures as a Prognostic Biomarker in Gastric Cancer

Shuyan Zhang,  Shanshan Li,  Jian-Lin Guo,  Ningyi Li,  Cai-Ning Zhang,  Jie Liu, 
  • First Published: 21 September 2021
Research Article
Open Access

[Retracted] Neurotransmitters and Electrophysiological Changes Might Work as Biomarkers for Diagnosing Affective Disorders

Fei Liang,  Rou Feng,  Simeng Gu,  Shan Jiang,  Xia Zhang,  Naling Li,  Minghong Xu,  Yiyuan Tang,  Fushun Wang, 
  • First Published: 20 September 2021

Research Article
Open Access

An Inflammation-Related Nine-Gene Signature to Improve Prognosis Prediction of Lung Adenocarcinoma

Ze-jing Liu,  Peng-xiao Hou,  Xi-xing Wang, 
  • First Published: 18 September 2021
Review Article
Open Access

[Retracted] Therapy Strategy of CD47 in Diffuse Large B-Cell Lymphoma (DLBCL)

Wenqi Zhang,  Yanfeng Fan,  Meng Li,  Linqi Yang,  Zhenya Zhang,  Lihong Liu, 
  • First Published: 17 September 2021

Research Article
Open Access

Urine Culture in Hospitalized Patients during 2014-2018: An Analysis on Pathogen Distribution and Drug Sensitivity

Dongkai Sun,  Peishan Cong,  Fengju Guan,  Shuai Liu,  Lijiang Sun,  Guiming Zhang, 
  • First Published: 16 September 2021
Research Article
Open Access

The Diagnostic Value of Synovial Fluid Lymphocytes in Gout Patients

Qidang Huang,  Yukai Huang,  Xin Guo,  Junming Chen,  Zheng Zhong,  Yuqi Liu,  Weiming Deng,  Tianwang Li, 
  • First Published: 16 September 2021
Research Article
Open Access

Cancer-Derived Exosomal miR-651 as a Diagnostic Marker Restrains Cisplatin Resistance and Directly Targets ATG3 for Cervical Cancer

Xiaofan Zhu,  Ling Long,  He Xiao,  Xuan He, 
  • First Published: 16 September 2021
Research Article
Open Access

Identification of Neuropeptides as Potential Crosstalks Linking Down Syndrome and Periodontitis Revealed by Transcriptomic Analyses

Yue Chen,  Xiaofei Yu,  Jia Kong, 
  • First Published: 11 September 2021
Research Article
Open Access

Clinical Utility of Serum Holotranscobalamin Measurements in Patients with First-Ever Ischemic Stroke

Oh Joo Kweon,  Yong Kwan Lim,  Mi-Kyung Lee,  Hye Ryoun Kim, 
  • First Published: 11 September 2021
Research Article
Open Access

Abnormal Expression and Prognosis Value of COG Complex Members in Kidney Renal Clear Cell Carcinoma (KIRC)

Yanjun Zhang,  Hui Lai,  Bin Tang, 
  • First Published: 08 September 2021
Research Article
Open Access

Differential Expression of Long Noncoding RNAs Reveals a Potential Biomarker for Intractable Pemphigus

Peng Qu,  Zixuan Huang,  Haiqin Zhu,  Jie Zheng,  Meng Pan, 
  • First Published: 07 September 2021
Research Article
Open Access

Research on the Segmentation of Biomarker for Chronic Central Serous Chorioretinopathy Based on Multimodal Fundus Image

Jianguo Xu,  Jianxin Shen,  Qin Jiang,  Cheng Wan,  Zhipeng Yan,  Weihua Yang, 
  • First Published: 06 September 2021
Research Article
Open Access

Construction of a Novel Immune-Related lncRNA Pair Signature with Prognostic Significance for Kidney Clear Cell Renal Cell Carcinoma

Jian-Xuan Sun,  Qi-Dong Xia,  Chen-Qian Liu,  Jin-Zhou Xu,  Yang Xun,  Jun-Lin Lu,  Jia Hu,  Shao-Gang Wang, 
  • First Published: 02 September 2021
Research Article
Open Access

EAD-Net: A Novel Lesion Segmentation Method in Diabetic Retinopathy Using Neural Networks

Cheng Wan,  Yingsi Chen,  Han Li,  Bo Zheng,  Nan Chen,  Weihua Yang,  Chenghu Wang,  Yan Li, 
  • First Published: 02 September 2021
Research Article
Open Access

Pyrroline-5-Carboxylate Reductase-2 Promotes Colorectal Cancer Progression via Activating PI3K/AKT/mTOR Pathway

Feng Yin,  Xiaoxia Huang,  Yi Xuan, 
  • First Published: 02 September 2021
Research Article
Open Access

Xp11.2 Translocation Renal Cell Carcinoma: Clinical Characteristics and Potential Prognostic Predictors

Jie Dong,  Weifeng Xu,  Zhigang Ji,  Boju Pan, 
  • First Published: 01 September 2021
Research Article
Open Access

Multiomics Differences in Lung Squamous Cell Carcinoma Patients with High Radiosensitivity Index Compared with Those with Low Radiosensitivity Index

Yajing Du,  Sujuan Yuan,  Xibing Zhuang,  Qi Zhang,  Tiankui Qiao, 
  • First Published: 31 August 2021
Research Article
Open Access

Decreased Serum NCAM Levels Associated with Cognitive Impairment in Vascular Dementia

Jun Zhao,  Wei Lu,  Junshan Li,  Lei Liu,  Xiumin Zhao, 
  • First Published: 31 August 2021
Research Article
Open Access

[Retracted] Development and Validation of Diagnostic Models for Hand-Foot-and-Mouth Disease in Children

Feng Zhuo,  Mengjie Yu,  Qiang Chen,  Nuoya Li,  Li Luo,  Meiying Hu,  Qi Dong,  Liang Hong,  Shouhua Zhang,  Qiang Tao, 
  • First Published: 31 August 2021

Research Article
Open Access

Analysis of Glomerular IgG Subclasses Switch in Idiopathic Membranous Nephropathy Classified by Glomerular Phospholipase A2 Receptor Antigen and Serum Antibody

Hao-yuan Cui,  Chao Li,  Hang Li,  Yu-bing Wen,  Lin Duan,  Yan Li,  Xi-wei Yan,  Yu-ting Hu,  Li-meng Chen,  Xue-mei Li, 
  • First Published: 30 August 2021
Review Article
Open Access

Signal Pathways and Markers Involved in Acute Lung Injury Induced by Acute Pancreatitis

Jialin Zhou,  Pengcheng Zhou,  Yingyi Zhang,  Guangzhi Wang,  Zhe Fan, 
  • First Published: 29 August 2021
Research Article
Open Access

Differences in Immunological Landscape between EGFR-Mutated and Wild-Type Lung Adenocarcinoma

Jia-Wei Luo,  Yan-Hua Guo,  Feng-Ying Wu,  Xue-Fei Li,  Xue-Cheng Sun,  Jia-Lu Wang,  Cai-Cun Zhou, 
  • First Published: 27 August 2021
Research Article
Open Access

Comprehensive Analysis of YTH Domain Family in Lung Adenocarcinoma: Expression Profile, Association with Prognostic Value, and Immune Infiltration

Kuan Hu,  Lei Yao,  Yuanliang Yan,  Lei Zhou,  Juanni Li, 
  • First Published: 27 August 2021
Research Article
Open Access

Expression of Four Autophagy-Related Genes Accurately Predicts the Prognosis of Gastrointestinal Cancer in Asian Patients

Hua Tang,  Yinyin Liang,  Shuyu Xu,  Rong Xia,  Jiemiao Shen,  Yuxin Zhang,  Xing Gong,  Yue Min,  Di Zhang,  Tie Zhao,  Shoulin Wang,  Yi Zhang,  Chao Wang, 
  • First Published: 26 August 2021
Research Article
Open Access

Albumin–Globulin Ratio Is an Independent Determinant of 28-Day Mortality in Patients with Critical Illness

Bin Liu,  Kun Xiao,  Peng Yan,  Tianyu Sun,  Jiang Wang,  Fei Xie,  Guoxin Mo,  Lixin Xie, 
  • First Published: 26 August 2021
Research Article
Open Access

ANGPTL3 Overexpression Suppresses the Development of Oncogenic Properties in Renal Cell Carcinoma via the Wnt/β-Catenin Signaling Pathway and Predicts Good Prognosis

Yu-jian Zhang,  Lin Zhang,  Fei Feng,  Qi-feng Cao, 
  • First Published: 25 August 2021
Research Article
Open Access

Association of Red Blood Cell Distribution Width Levels with Connective Tissue Disease-Associated Interstitial Lung Disease (CTD-ILD)

Shenyun Shi,  Ling Chen,  Xianhua Gui,  Lulu Chen,  Xiaohua Qiu,  Min Yu,  Yonglong Xiao, 
  • First Published: 20 August 2021
Research Article
Open Access

Targeting lncRNA PSMA3-AS1, a Prognostic Marker, Suppresses Malignant Progression of Oral Squamous Cell Carcinoma

Xinghua Cao,  Kefeng Luan,  Jie Yang,  Yundong Huang, 
  • First Published: 20 August 2021
Research Article
Open Access

Biomarkers of Inflammation and Inflammation-Related Indexes upon Emergency Department Admission Are Predictive for the Risk of Intensive Care Unit Hospitalization and Mortality in Acute Poisoning: A 6-Year Prospective Observational Study

Catalina Lionte,  Cristina Bologa,  Victorita Sorodoc,  Ovidiu Rusalim Petris,  Gabriela Puha,  Alexandra Stoica,  Alexandr Ceasovschih,  Elisabeta Jaba,  Laurentiu Sorodoc, 
  • First Published: 19 August 2021
Research Article
Open Access

High mRNA Expression of CENPL and Its Significance in Prognosis of Hepatocellular Carcinoma Patients

Zhongyuan Cui,  Lijia Xiao,  Fengsui Chen,  Jielong Wang,  Haiyan Lin,  Dongliang Li,  Zhixian Wu, 
  • First Published: 18 August 2021
Review Article
Open Access

Immune Checkpoints: Therapeutic Targets for Pituitary Tumors

Ding Nie,  Yimeng Xue,  Qiuyue Fang,  Jianhua Cheng,  Bin Li,  Dawei Wang,  Chuzhong Li,  Songbai Gui,  Yazhuo Zhang,  Peng Zhao, 
  • First Published: 17 August 2021
Research Article
Open Access

RNA-Binding Motif Protein 11 (RBM11) Serves as a Prognostic Biomarker and Promotes Ovarian Cancer Progression

Chunhong Fu,  Ming Yuan,  Jie Sun,  Gang Liu,  Xiaojuan Zhao,  Wei Chang,  Zhongling Ma, 
  • First Published: 16 August 2021
Research Article
Open Access

APOA-5 Genetic Variant rs662799: Role in Lipid Changes and Insulin Resistance after a Mediterranean Diet in Caucasian Obese Subjects

Daniel de Luis,  Olatz Izaola,  David Primo, 
  • First Published: 13 August 2021
Research Article
Open Access

Bibliometrics Analysis of Diagnostic Test Accuracy Studies of Bladder Cancer

Yuan Zhang,  Yao Xu,  Shuo Li, 
  • First Published: 13 August 2021
Research Article
Open Access

Identification of Six Autophagy-Related-lncRNA Prognostic Biomarkers in Uveal Melanoma

Yao Chen,  Lu Chen,  Jinwei Wang,  Jia Tan,  Sha Wang, 
  • First Published: 13 August 2021
Research Article
Open Access

Hyponatremia and Renal Venous Congestion in Heart Failure Patients

Alexandru Caraba,  Stela Iurciuc,  Andreea Munteanu,  Mircea Iurciuc, 
  • First Published: 12 August 2021
Research Article
Open Access

Construction and Validation of a Novel Prognostic Signature for Intestinal Type of Gastric Cancer

Fan Zhang,  Ewetse Paul Maswikiti,  Yucai Wei,  Wenzhang Wu,  Yumin Li, 
  • First Published: 12 August 2021
Research Article
Open Access

Gender-Related Difference in D-Dimer Level Predicts In-Hospital Heart Failure after Primary PCI for ST-Segment Elevation Myocardial Infarction

Li Li,  Wei Wang,  Tai Li,  Ying Sun,  Yanjun Gao,  Lin Wang,  Heng-Chen Yao, 
  • First Published: 11 August 2021
Research Article
Open Access

Serum Neuropeptide Y: A Potential Prognostic Marker of Intracerebral Hemorrhage

Weiming Sun,  Zhenxing Zhang,  Xu Feng,  Xin Sui,  Ye Miao, 
  • First Published: 10 August 2021
Review Article
Open Access

A Review of Novel Cardiac Biomarkers in Acute or Chronic Cardiovascular Diseases: The Role of Soluble ST2 (sST2), Lipoprotein-Associated Phospholipase A2 (Lp-PLA2), Myeloperoxidase (MPO), and Procalcitonin (PCT)

Junpei Li,  Tianyu Cao,  Yaping Wei,  Nan Zhang,  Ziyi Zhou,  Zhuo Wang,  Jingyi Li,  Yue Zhang,  Sijia Wang,  Ping Wang,  Nannan Cheng,  Lijing Ye,  Minghui Li,  Yu Yu,  Congcong Ding,  Ziheng Tan,  Biming Zhan,  Qiangqiang He,  Huihui Bao,  Yanqing Wu,  Lishun Liu,  Jianping Li,  Xiping Xu,  Xiaoshu Cheng,  Xiao Huang, 
  • First Published: 10 August 2021
Research Article
Open Access

Long Noncoding RNA LINC01554 as a Novel Biomarker for Diagnosis and Prognosis Prediction of Epithelial Ovarian Cancer

Ting Luo,  Yan Jiang,  Jing Yang, 
  • First Published: 10 August 2021
Research Article
Open Access

circRNA hsa_circ_0005909 Predicts Poor Prognosis and Promotes the Growth, Metastasis, and Drug Resistance of Non-Small-Cell Lung Cancer via the miRNA-338-3p/SOX4 Pathway

He-mei Song,  Dan Meng,  Jin-ping Wang,  Xiao-yan Zhang, 
  • First Published: 09 August 2021
Research Article
Open Access

Overexpression of CXCR7 is a Novel Indicator for Enzalutamide Resistance in Castration-Resistant Prostate Cancer Patients

Yong Luo,  Qiankun Li,  Xiaobing Yang,  Dechao Wei,  Bingfu Feng,  Mingchuan Li,  Yili Han,  Jiahui Zhao,  Yunhua Lin,  Qing Li,  Zhu Hou,  Hongyu Zhuang,  Yongguang Jiang, 
  • First Published: 09 August 2021
Research Article
Open Access

Cysteine-Rich Intestinal Protein 1 Served as an Epithelial Ovarian Cancer Marker via Promoting Wnt/β-Catenin-Mediated EMT and Tumour Metastasis

Yujuan Liu,  Wenyu Li,  Ji Luo,  Yiguo Wu,  Yuanyuan Xu,  Tingtao Chen,  Wei Zhang,  Fen Fu, 
  • First Published: 09 August 2021
Research Article
Open Access

Role of ssDNA as a Noninvasive Indicator for the Diagnosis and Prognosis of Hepatocellular Carcinoma: An Exploratory Study

Qi Zhao,  Yiqiu Xu,  Dandan Yuan,  Junjun Yang,  Ying Wang,  Guorong Shen,  Xuewen Huang, 
  • First Published: 05 August 2021
Research Article
Open Access

[Retracted] Identification of Ferroptosis-Related Long Noncoding RNA and Construction of a Novel Prognostic Signature for Gastric Cancer

WenZheng Chen,  ZongFeng Feng,  JianFeng Huang,  PengCheng Fu,  JianBo Xiong,  Yi Cao,  Yi Liu,  Yi Tu,  ZhengRong Li,  ZhiGang Jie,  Tao Xiao, 
  • First Published: 04 August 2021

Research Article
Open Access

Perineural Invasion Should Be Regarded as an Intermediate-Risk Factor for Recurrence in Surgically Treated Cervical Cancer: A Propensity Score Matching Study

Ting Wan,  Hua Tu,  Lili Liu,  He Huang,  Yanling Feng,  Jihong Liu, 
  • First Published: 04 August 2021
Research Article
Open Access

Neutrophil Extracellular Traps in Fatal COVID-19-Associated Lung Injury

Astrid Obermayer,  Lisa-Maria Jakob,  Jasmin D. Haslbauer,  Matthias S. Matter,  Alexandar Tzankov,  Walter Stoiber, 
  • First Published: 02 August 2021
Research Article
Open Access

Research on an Intelligent Lightweight-Assisted Pterygium Diagnosis Model Based on Anterior Segment Images

Bo Zheng,  Yunfang Liu,  Kai He,  Maonian Wu,  Ling Jin,  Qin Jiang,  Shaojun Zhu,  Xiulan Hao,  Chenghu Wang,  Weihua Yang, 
  • First Published: 29 July 2021
Research Article
Open Access

Reproduction of the Cancer Genome Atlas (TCGA) and Asian Cancer Research Group (ACRG) Gastric Cancer Molecular Classifications and Their Association with Clinicopathological Characteristics and Overall Survival in Moroccan Patients

Jean Paul Nshizirungu,  Sanae Bennis,  Ihsane Mellouki,  Mohammed Sekal,  Dafr-Allah Benajah,  Nada Lahmidani,  Hicham El Bouhaddouti,  Karim Ibn Majdoub,  Sidi Adil Ibrahimi,  Sónia Pires Celeiro,  Marta Viana-Pereira,  Fernanda Franco Munari,  Guilherme Gomes Ribeiro,  Vinicius Duval,  Iara Santana,  Rui Manuel Reis, 
  • First Published: 29 July 2021
Research Article
Open Access

Plaque Length Predicts the Incidence of Microembolic Signals in Acute Anterior Circulation Stroke

Liming Zhao,  Hongqin Zhao,  Yicheng Xu,  Aijuan Zhang,  Jiatang Zhang,  Chenglin Tian, 
  • First Published: 29 July 2021
Research Article
Open Access

Interleukin-18: A Novel Participant in the Occurrence, Development, and Drug Therapy of Obliterative Bronchiolitis Postlung Transplantation

Ping Shu,  Wei Zhang,  Yanfei Zhang,  Yanfeng Zhao,  Yuping Li,  Xiaoqing Zhang, 
  • First Published: 28 July 2021
Research Article
Open Access

Cyclin B2 (CCNB2) Stimulates the Proliferation of Triple-Negative Breast Cancer (TNBC) Cells In Vitro and In Vivo

Shuai Wu,  Rui Su,  Hongyan Jia, 
  • First Published: 27 July 2021
Research Article
Open Access

Significant Diagnostic and Prognostic Value of FLAD1 and Related MicroRNAs in Breast Cancer after a Pan-Cancer Analysis

Mei Mei,  Wenting Song,  Yingjun Wang,  Mingzhi Zhang, 
  • First Published: 22 July 2021
Review Article
Open Access

Ischemia-Modified Albumin: Origins and Clinical Implications

Alla Shevtsova,  Iuliia Gordiienko,  Viktoriia Tkachenko,  Galyna Ushakova, 
  • First Published: 20 July 2021
Research Article
Open Access

The Prognostic Determinant of Interleukin-10 in Patients with Acute Ischemic Stroke: An Analysis from the Perspective of Disease Management

Wen Sun,  Shuhui Wang,  Shanji Nan, 
  • First Published: 19 July 2021
Research Article
Open Access

lncRNA TSPEAR-AS2, a Novel Prognostic Biomarker, Promotes Oral Squamous Cell Carcinoma Progression by Upregulating PPM1A via Sponging miR-487a-3p

Yi-chao Xia,  Jun Cao,  Jing Yang,  Ying Zhang,  Yong-sheng Li, 
  • First Published: 19 July 2021
Review Article
Open Access

The Uprising of Mitochondrial DNA Biomarker in Cancer

Siti Zulaikha Nashwa Mohd Khair,  Siti Muslihah Abd Radzak,  Abdul Aziz Mohamed Yusoff, 
  • First Published: 16 July 2021
Research Article
Open Access

Correlation between Family RB1 Gene Pathogenic Variant with Clinical Features and Prognosis of Retinoblastoma under 5 Years Old

Yi Zhang,  Yizhuo Wang,  Dongsheng Huang,  Jianmin Ma,  Weiling Zhang,  Huali Gu,  Yan Zhou,  You Yi,  Pinwei Zhang, 
  • First Published: 13 July 2021
Research Article
Open Access

Coronary Artery Disease: Association Study of 5 Loci with Angiographic Indices of Disease Severity

Neda M. Bogari,  Reem M. Allam,  Abdellatif Bouazzaoui,  Osama Elkhateeb,  Massimo Porqueddu,  Gualtiero I. Colombo, 
  • First Published: 13 July 2021
Research Article
Open Access

NMU Is a Poor Prognostic Biomarker in Patients with Lung Adenocarcinoma

Yan Tang,  Chunsheng Hu, 
  • First Published: 13 July 2021
Research Article
Open Access

Autoantibodies against p53, MMP-7, and Hsp70 as Potential Biomarkers for Detection of Nonmelanoma Skin Cancers

Shi-Han Yang,  Can-Tong Liu,  Chao-Qun Hong,  Ze-Yuan Huang,  Huan-Zhu Wang,  Lai-Feng Wei,  Yi-Wei Lin,  Hai-Peng Guo,  Yu-Hui Peng,  Yi-Wei Xu, 
  • First Published: 12 July 2021
Research Article
Open Access

Association between Uric Acid and In-Hospital Heart Failure in Patients with Acute Myocardial Infarction Undergoing Percutaneous Coronary Intervention

Cun-Fei Liu,  Kai-You Song,  Wei-Ning Zhou,  Yan-Jin Wei, 
  • First Published: 09 July 2021
Research Article
Open Access

ESAT-6 and Ag85A Synthetic Peptides as Candidates for an Immunodiagnostic Test in Children with a Clinical Suspicion of Tuberculosis

Zaida Araujo,  Carlos Fernández de Larrea,  Diana López,  Jaime Isern-Kebschull,  Jacobus Henri de Waard,  Isabel Hagel,  Milena Camargo,  Magnolia Vanegas,  Manuel A. Patarroyo, 
  • First Published: 07 July 2021
Research Article
Open Access

Optical Coherence Tomography Angiography as a Noninvasive Assessment of Cerebral Microcirculatory Disorders Caused by Carotid Artery Stenosis

Xinyue Li,  Shiyi Zhu,  Sujun Zhou,  Yanwei Zhang,  Yiheng Ding,  Bingjie Zheng,  Pei Wu,  Yan Shi,  Hong Zhang,  Huaizhang Shi, 
  • First Published: 06 July 2021
Corrigendum
Open Access

Corrigendum to “Long Noncoding RNA TUG1/miR-29c Axis Affects Cell Proliferation, Invasion, and Migration in Human Pancreatic Cancer”

Yebin Lu,  Ling Tang,  Zhipeng Zhang,  Shengyu Li,  Shuai Liang,  Liandong Ji,  Bo Yang,  Yu Liu,  Wei Wei, 
  • First Published: 05 July 2021

Research Article
Open Access

Systematic Analysis of the Oncogenic Role of WDR62 in Human Tumors

Yulan Bu,  Lihua Zhang,  Xiaolin Ma,  Rui Wang,  Xuecheng Zhang,  Jiaqiu Li, 
  • First Published: 02 July 2021
Research Article
Open Access

MicroRNA-181b Serves as a Circulating Biomarker and Regulates Inflammation in Heart Failure

Hongxiao Yang,  Lina Shan,  Yunan Gao,  Lin Li,  Guifen Xu,  Bin Wang,  Xiaoxue Yin,  Chengfang Gao,  Jiaren Liu,  Wei Yang, 
  • First Published: 02 July 2021
Research Article
Open Access

GABPA Expression in Endometrial Carcinoma: A Prognostic Marker

Xiaoxue Ma,  Qianhan Lin,  Gongting Cui,  Jing Zhao,  Xuan Wei,  Rui Li,  Hongluan Mao,  Yanhui Ma,  Peishu Liu,  Yingxin Pang, 
  • First Published: 30 June 2021
Research Article
Open Access

Comparison of Percutaneous Kyphoplasty with or without Pedicle Screw Fixation in Osteoporotic Thoracolumbar Vertebral Fractures: A Retrospective Study

Dichao Huang,  Jichong Ying,  Dingli Xu,  Jianming Chen,  Jianlei Liu,  Tianming Yu,  Yunqiang Zhuang,  Long Zhou, 
  • First Published: 30 June 2021
Research Article
Open Access

[Retracted] The Mechanism of Xiaoyao San in the Treatment of Ovarian Cancer by Network Pharmacology and the Effect of Stigmasterol on the PI3K/Akt Pathway

Meng Li,  Wenqi Zhang,  Linqi Yang,  Huibing Wang,  Yihan Wang,  Kai Huang,  Wei Zhang, 
  • First Published: 30 June 2021

Review Article
Open Access

Peripheral Oxidation Markers in Down Syndrome Patients: The Better and the Worse

Dominik Szwajgier,  Ewa Baranowska-Wójcik,  Joanna Grzelczyk,  Wioletta Żukiewicz-Sobczak, 
  • First Published: 29 June 2021
Research Article
Open Access

Topological Organization Alterations of Whole-Brain Functional Networks in Patients with Childhood Absence Epilepsy: Associations with Treatment Effects

Xueyu Wang,  Peng Fang,  Dongmei Jiao,  Tian Hu,  Qi Yang,  Wei Liang,  Yijun Li,  Yibing Yan,  Libo Liu, 
  • First Published: 28 June 2021
Research Article
Open Access

[Retracted] Pathogenic Characterization of a Porcine Circovirus Type 3 Isolate from Heilongjiang, China

Menghang Wang,  Ying Yu,  Jianan Wu,  Fandan Meng,  Yandong Tang,  Shujie Wang,  Yu Wang,  Hongliang Cui,  Xijun He,  Yabin Tu,  Gang Wang,  Xuehui Cai, 
  • First Published: 25 June 2021

Research Article
Open Access

ACE2 and Apelin-13: Biomarkers with a Prognostic Value in Congestive Heart Failure

Cerasela Mihaela Goidescu,  Roxana Mihaela Chiorescu,  Mocan-Hognogi Larisa Diana,  Mihaela Mocan,  Mirela Anca Stoia,  Florin Petru Anton,  Anca Daniela Farcaş, 
  • First Published: 23 June 2021
Review Article
Open Access

Coexpression of Helios in Foxp3+ Regulatory T Cells and Its Role in Human Disease

Wen-qing Yu,  Ning-fei Ji,  Cheng-jing Gu,  Yan-li Wang,  Mao Huang,  Ming-shun Zhang, 
  • First Published: 23 June 2021
Research Article
Open Access

Diaphragm Thickening Fraction as a Prognostic Imaging Marker for Postoperative Pulmonary Complications in Robot-Assisted Laparoscopic Prostatectomy Requiring the Trendelenburg Position and Pneumoperitoneum

Jihion Yu,  Yongsoo Lee,  Jun-Young Park,  Jai-Hyun Hwang,  Young-Kug Kim, 
  • First Published: 23 June 2021
Research Article
Open Access

Classification of Left Atrial Diseased Tissue Burden Determined by Automated Voltage Analysis Predicts Outcomes after Ablation for Atrial Fibrillation

Szilvia Herczeg,  John J. Keaney,  Edward Keelan,  Claire Howard,  Katie Walsh,  Laszlo Geller,  Gabor Szeplaki,  Joseph Galvin, 
  • First Published: 23 June 2021
Research Article
Open Access

Hyperprogressive Disease Caused by PD-1 Inhibitors for the Treatment of Pan-Cancer

Shiyun Chen,  Miaomiao Gou,  Huan Yan,  Mengjiao Fan,  Yuting Pan,  Runjia Fan,  Niansong Qian,  Guanghai Dai, 
  • First Published: 22 June 2021
Research Article
Open Access

Development of a Ferroptosis-Related lncRNA Signature to Predict the Prognosis and Immune Landscape of Bladder Cancer

Ranran Zhou,  Jingjing Liang,  Hu Tian,  Qi Chen,  Cheng Yang,  Cundong Liu, 
  • First Published: 21 June 2021
Research Article
Open Access

Jiangzhi Ligan Decoction Inhibits GSDMD-Mediated Canonical/Noncanonical Pyroptosis Pathways and Alleviates High-Fat Diet-Induced Nonalcoholic Fatty Liver Disease

Kangkang Yin,  Xiao Zhou,  Wei Jiang,  Linlin Wang,  Ziwei Dai,  Biao Tang, 
  • First Published: 19 June 2021
Research Article
Open Access

Serum IL-5 and IFN-γ Are Novel Predictive Biomarkers for Anti-PD-1 Treatment in NSCLC and GC Patients

Qiu Zhao,  Yanzhi Bi,  Huiting Sun,  Min Xiao, 
  • First Published: 19 June 2021
Research Article
Open Access

Prognostic Value of GDF-15 in Predicting Prolonged Intensive Care Stay following Cardiac Surgery: A Pilot Study

Henry Barton,  Elisabeth Zechendorf,  Dirk Ostareck,  Antje Ostareck-Lederer,  Christian Stoppe,  Rashad Zayat,  Tim Simon-Philipp,  Gernot Marx,  Johannes Bickenbach, 
  • First Published: 16 June 2021
Research Article
Open Access

Enhanced Visualization of Retinal Microvasculature via Deep Learning on OCTA Image Quality

Yishuang Xu,  Yu Su,  Dihao Hua,  Peter Heiduschka,  Wenliang Zhang,  Tianyue Cao,  Jingcheng Liu,  Zhenyu Ji,  Nicole Eter, 
  • First Published: 16 June 2021
Research Article
Open Access

CCL24 Protects Renal Function by Controlling Inflammation in Podocytes

Youdi Wang,  Xue Wu,  Mengya Geng,  Jiamin Ding,  Kangjia Lv,  Hui Du,  Jiahui Ding,  Wenjun Pei,  Xin Hu,  Jing Gu,  Lizhuo Wang,  Yao Zhang,  Jialin Gao, 
  • First Published: 16 June 2021
Research Article
Open Access

A Five-Gene Prognostic Nomogram Predicting Disease-Free Survival of Differentiated Thyroid Cancer

Pan Ruchong,  Tang Haiping,  Wang Xiang, 
  • First Published: 16 June 2021
Research Article
Open Access

Altered Small-World Functional Network Topology in Patients with Optic Neuritis: A Resting-State fMRI Study

Ke Song,  Juan Li,  Yuanqiang Zhu,  Fang Ren,  Lingcan Cao,  Zi-Gang Huang, 
  • First Published: 15 June 2021
Research Article
Open Access

Correlation between C-Reactive Protein to Albumin Ratio and Disease Activity in Patients with Axial Spondyloarthritis

Zheng Zhong,  Yukai Huang,  Yuqi Liu,  Junming Chen,  Meng Liu,  Qidang Huang,  Shaoling Zheng,  Xin Guo,  Weiming Deng,  Tianwang Li, 
  • First Published: 14 June 2021
Corrigendum
Open Access

Corrigendum to “scFv against HSP60 of Strongyloides sp. and Its Application in the Evaluation of Parasite Frequency in the Elderly”

Camila Botelho Miguel,  Marcelo Arantes Levenhagen,  Fabiana de Almeida Araújo Santos,  Julia Maria Costa-Cruz,  Luiz Ricardo Goulart,  Patrícia Terra Alves,  Carlos Ueira-Vieira,  Patrícia Kellen Martins Oliveira Brito,  Angelica Oliveira Gomes,  Javier Emilio Lazo-Chica,  Carlo José Freire Oliveira,  Wellington Francisco Rodrigues, 
  • First Published: 14 June 2021

Research Article
Open Access

CALCB rs3829222 T/T Genotype and Low Expression of CALCB Are High-Risk Factors for Adenoid Cystic Carcinoma of Salivary Gland

Chaobin Dai,  Bin Zhang,  Yunyang Liao,  Qicai Liu,  Feiguang Wu,  Xiaoting Lv,  Kai Zeng,  Xiaofeng Zhu, 
  • First Published: 14 June 2021
Research Article
Open Access

Lack of Association of LPA Gene Polymorphisms with Coronary Artery Disease in Pakistani Subjects

Saleem Ullah Shahid,  Shabana N A,  Steve Humphries, 
  • First Published: 12 June 2021
Research Article
Open Access

Clinicopathological, Radiological, and Molecular Features of Primary Lung Adenocarcinoma with Morule-Like Components

Li-Li Wang,  Li Ding,  Peng Zhao,  Jing-Jing Guan,  Xiao-Bin Ji,  Xiao-Li Zhou,  Shi-Hong Shao,  Yu-Wei Zou,  Wei-Wei Fu,  Dong-Liang Lin, 
  • First Published: 12 June 2021
Research Article
Open Access

Identification of an m6A-Related Signature as Biomarker for Hepatocellular Carcinoma Prognosis and Correlates with Sorafenib and Anti-PD-1 Immunotherapy Treatment Response

Hongye Jiang,  Gang Ning,  Yensheng Wang,  Weibiao Lv, 
  • First Published: 11 June 2021
Research Article
Open Access

PFKFB4 Overexpression Facilitates Proliferation by Promoting the G1/S Transition and Is Associated with a Poor Prognosis in Triple-Negative Breast Cancer

Yu-Chen Cai,  Hang Yang,  Hong-Bo Shan,  Hui-Fang Su,  Wen-Qi Jiang,  Yan-Xia Shi, 
  • First Published: 10 June 2021
Research Article
Open Access

MXRA5 Is a Novel Immune-Related Biomarker That Predicts Poor Prognosis in Glioma

Jin-Zhang Sun,  Jin-Hao Zhang,  Jia-Bo Li,  Feng Yuan,  Lu-Qing Tong,  Xu-Ya Wang,  Lu-Lu Chen,  Xiao-Guang Fan,  Yi-Ming Zhang,  Xiao Ren,  Chen Zhang,  Sheng-Ping Yu,  Xue-Jun Yang, 
  • First Published: 10 June 2021
Research Article
Open Access

Hepatic Steatosis Index and Chronic Kidney Disease among Middle-Aged Individuals: A Large-Scale Study in Japan

Hirotaka Ochiai,  Takako Shirasawa,  Takahiko Yoshimoto,  Satsue Nagahama,  Ken Sakamoto,  Minami Azuma,  Akatsuki Kokaze, 
  • First Published: 10 June 2021
Research Article
Open Access

Machine Learning of Schizophrenia Detection with Structural and Functional Neuroimaging

Dafa Shi,  Yanfei Li,  Haoran Zhang,  Xiang Yao,  Siyuan Wang,  Guangsong Wang,  Ke Ren, 
  • First Published: 09 June 2021
Research Article
Open Access

A Nomogram Prediction of Length of Hospital Stay in Patients with COVID-19 Pneumonia: A Retrospective Cohort Study

Kang Li,  Chi Zhang,  Ling Qin,  Chaoran Zang,  Ang Li,  Jianping Sun,  Yan Zhao,  Yingmei Feng,  Yonghong Zhang, 
  • First Published: 08 June 2021
Research Article
Open Access

Association between Inflammatory Factors in the Aqueous Humor and Hyperreflective Foci in Patients with Intractable Macular Edema Treated with Antivascular Endothelial Growth Factor

Min Li,  Jing Li,  Kaichuan Chen,  Jia Wang,  Minjie Sheng,  Bing Li, 
  • First Published: 08 June 2021
Research Article
Open Access

FLT3 Amplification as Double Minute Chromosomes in a Patient with Chronic Myelomonocytic Leukemia

Heyang Zhang,  Xiaoxue Wang,  Shibo Li,  Xianfu Wang,  Xianglan Lu,  Ming Li,  Hua Wang,  Ying Liu,  Hui Pang,  Lijun Zhang, 
  • First Published: 07 June 2021
Review Article
Open Access

False-Positive Maternal Serum Screens in the Second Trimester as Markers of Placentally Mediated Complications Later in Pregnancy: A Systematic Review and Meta-Analysis

Christy L. Pylypjuk,  Joel Monarrez-Espino, 
  • First Published: 04 June 2021
Research Article
Open Access

m6A RNA Methylation Regulators Elicit Malignant Progression and Predict Clinical Outcome in Hepatocellular Carcinoma

Wenli Li,  Jun Liu,  Zhanzhong Ma,  Xiaofeng Zhai,  Binbin Cheng,  Hetong Zhao, 
  • First Published: 04 June 2021
Research Article
Open Access

Prognostic Value of the Red Cell Distribution Width in Patients with Sepsis-Induced Acute Respiratory Distress Syndrome: A Retrospective Cohort Study

Huabin Wang,  Junbin Huang,  Wenhua Liao,  Jiannan Xu,  Zhongyuan He,  Yong Liu,  Zhijie He,  Chun Chen, 
  • First Published: 02 June 2021
Research Article
Open Access

A Scoring System for Outpatient Orthopedist to Preliminarily Distinguish Spinal Metastasis from Spinal Tuberculosis: A Retrospective Analysis of 141 Patients

Xing Du,  Yuxiao She,  Yunsheng Ou,  Yong Zhu,  Wei Luo,  Dianming Jiang, 
  • First Published: 29 May 2021
Research Article
Open Access

Combining Calcitonin and Procalcitonin and Rheumatoid Arthritis-Related Biomarkers Improve Diagnostic Outcomes in Early Rheumatoid Arthritis

Yingwen Liu,  Jing Shi,  Bo Wang,  Lijing Zhou,  Xiaolan Zhou,  Yane Du,  Dandan Li,  Liang Duan,  Qin Hu,  Weixian Chen,  Pu Li, 
  • First Published: 27 May 2021
Research Article
Open Access

Cancer-Associated Fibroblasts Regulate Bladder Cancer Invasion and Metabolic Phenotypes through Autophagy

Dahai Dong,  Yu Yao,  Jinlei Song,  Lijiang Sun,  Guiming Zhang, 
  • First Published: 25 May 2021
Research Article
Open Access

Association of Polymorphisms in Vitamin D-Metabolizing Enzymes DHCR7 and CYP2R1 with Cancer Susceptibility: A Systematic Review and Meta-Analysis

Jing Wen,  Jia Li,  Xinyuan Liang,  Aiping Wang, 
  • First Published: 22 May 2021
Research Article
Open Access

Fibronectin 1: A Potential Biomarker for Ovarian Cancer

Huijing Bao,  Qianyu Huo,  Qin Yuan,  Chen Xu, 
  • First Published: 22 May 2021
Research Article
Open Access

Anti-N-Methyl-D-Aspartate Receptor Encephalitis Associated with Ovarian Teratoma in South China-Clinical Features, Treatment, Immunopathology, and Surgical Outcomes of 21 Cases

Huiyun Jiang,  Huixia Ye,  Yifeng Wang,  Yunhui Li,  Ying Wang,  Xiaomao Li, 
  • First Published: 21 May 2021
Research Article
Open Access

Identification of Novel Biomarkers for Evaluating Disease Severity in House-Dust-Mite-Induced Allergic Rhinitis by Serum Metabolomics

Shaobing Xie,  Hua Zhang,  Zhihai Xie,  Yongzhen Liu,  Kelei Gao,  Junyi Zhang,  Shumin Xie,  Fengjun Wang,  Ruohao Fan,  Weihong Jiang, 
  • First Published: 19 May 2021
Research Article
Open Access

Combination Model of Thyrotrophin Receptor Antibody and Volumetric Orbital Apex Crowding Index as an Indicator of Dysthyroid Optic Neuropathy

Zhihong Deng,  Lu Chen,  Jia Tan,  Sha Wang,  Dan Liu,  Jinwei Wang,  Chengzhi Jiang,  Jie Yang,  Bei Xu, 
  • First Published: 19 May 2021
Review Article
Open Access

FGF23: A Review of Its Role in Mineral Metabolism and Renal and Cardiovascular Disease

Anna Kurpas,  Karolina Supeł,  Karolina Idzikowska,  Marzenna Zielińska, 
  • First Published: 18 May 2021
Research Article
Open Access

HDL-C/apoA-I Ratio Is Associated with the Severity of Coronary Artery Stenosis in Diabetic Patients with Acute Coronary Syndrome

Lizhe Sun,  Manyun Guo,  Chenbo Xu,  Xiangrui Qiao,  Yiming Hua,  Gulinigaer Tuerhongjiang,  Bowen Lou,  Ruifeng Li,  Xiaofang Bai,  Juan Zhou,  Yue Wu,  Jianqing She,  Zuyi Yuan, 
  • First Published: 18 May 2021
Research Article
Open Access

Identification of Disease-Specific Hub Biomarkers and Immune Infiltration in Osteoarthritis and Rheumatoid Arthritis Synovial Tissues by Bioinformatics Analysis

Fei Sun,  Jian lin Zhou,  Pu ji Peng,  Chen Qiu,  Jia rui Cao,  Hao Peng, 
  • First Published: 17 May 2021
Research Article
Open Access

Simple Parameters from Complete Blood Count Predict In-Hospital Mortality in COVID-19

Mattia Bellan,  Danila Azzolina,  Eyal Hayden,  Gianluca Gaidano,  Mario Pirisi,  Antonio Acquaviva,  Gianluca Aimaretti,  Paolo Aluffi Valletti,  Roberto Angilletta,  Roberto Arioli,  Gian Carlo Avanzi,  Gianluca Avino,  Piero Emilio Balbo,  Giulia Baldon,  Francesca Baorda,  Emanuela Barbero,  Alessio Baricich,  Michela Barini,  Francesco Barone-Adesi,  Sofia Battistini,  Michela Beltrame,  Matteo Bertoli,  Stephanie Bertolin,  Marinella Bertolotti,  Marta Betti,  Flavio Bobbio,  Paolo Boffano,  Lucio Boglione,  Silvio Borrè,  Matteo Brucoli,  Elisa Calzaducca,  Edoardo Cammarata,  Vincenzo Cantaluppi,  Roberto Cantello,  Andrea Capponi,  Alessandro Carriero,  Giuseppe Francesco Casciaro,  Luigi Mario Castello,  Federico Ceruti,  Guido Chichino,  Emilio Chirico,  Carlo Cisari,  Micol Giulia Cittone,  Crizia Colombo,  Cristoforo Comi,  Eleonora Croce,  Tommaso Daffara,  Pietro Danna,  Francesco Della Corte,  Simona De Vecchi,  Umberto Dianzani,  Davide Di Benedetto,  Elia Esposto,  Fabrizio Faggiano,  Zeno Falaschi,  Daniela Ferrante,  Alice Ferrero,  Ileana Gagliardi,  Alessandra Galbiati,  Silvia Gallo,  Pietro Luigi Garavelli,  Clara Ada Gardino,  Massimiliano Garzaro,  Maria Luisa Gastaldello,  Francesco Gavelli,  Alessandra Gennari,  Greta Maria Giacomini,  Irene Giacone,  Valentina Giai Via,  Francesca Giolitti,  Laura Cristina Gironi,  Carla Gramaglia,  Leonardo Grisafi,  Ilaria Inserra,  Marco Invernizzi,  Marco Krengli,  Emanuela Labella,  Irene Cecilia Landi,  Raffaella Landi,  Ilaria Leone,  Veronica Lio,  Luca Lorenzini,  Antonio Maconi,  Mario Malerba,  Giulia Francesca Manfredi,  Maria Martelli,  Letizia Marzari,  Paolo Marzullo,  Marco Mennuni,  Claudia Montabone,  Umberto Morosini,  Marco Mussa,  Ilaria Nerici,  Alessandro Nuzzo,  Carlo Olivieri,  Samuel Alberto Padelli,  Massimiliano Panella,  Andrea Parisini,  Alessio Paschè,  Filippo Patrucco,  Giuseppe Patti,  Alberto Pau,  Anita Rebecca Pedrinelli,  Ilaria Percivale,  Luca Ragazzoni,  Roberta Re,  Cristina Rigamonti,  Eleonora Rizzi,  Andrea Rognoni,  Annalisa Roveta,  Luigia Salamina,  Matteo Santagostino,  Massimo Saraceno,  Paola Savoia,  Marco Sciarra,  Andrea Schimmenti,  Lorenza Scotti,  Enrico Spinoni,  Carlo Smirne,  Vanessa Tarantino,  Paolo Amedeo Tillio,  Stelvio Tonello,  Rosanna Vaschetto,  Veronica Vassia,  Domenico Zagaria,  Elisa Zavattaro,  Patrizia Zeppegno,  Francesca Zottarelli,  Pier Paolo Sainaghi, 
  • First Published: 13 May 2021
Research Article
Open Access

Elevated Serum Small Dense Low-Density Lipoprotein Cholesterol May Increase the Risk and Severity of Coronary Heart Disease and Predict Cardiovascular Events in Patients with Type 2 Diabetes Mellitus

Juan Huang,  Jun-Xu Gu,  Hui-Zhang Bao,  Shan-Shan Li,  Xiao-Qin Yao,  Ming Yang,  Yang Li,  Ai-Min Zhang,  Yue Yin,  Na Zhang,  Mei Jia,  Ming Su, 
  • First Published: 10 May 2021
Research Article
Open Access

A Risk Signature with Autophagy-Related Long Noncoding RNAs for Predicting the Prognosis of Clear Cell Renal Cell Carcinoma: Based on the TCGA Database and Bioinformatics

Yundong Xuan,  Weihao Chen,  Kan Liu,  Yu Gao,  Shidong Zuo,  Baojun Wang,  Xin Ma,  Xu Zhang, 
  • First Published: 07 May 2021
Research Article
Open Access

Personalized Prechemotherapy Education Reduces Peri-Chemotherapy Anxiety in Colorectal Cancer Patients

Shasha Li,  Lihong Li,  Xin Shi,  Mingshu Wang,  Xiaoli Song,  Feng Cui, 
  • First Published: 03 May 2021
Research Article
Open Access

Clinical Features of Intestinal Ulcers Complicated by Epstein-Barr Virus Infection: Importance of Active Infection

Yuyuan Liu,  Yuqin Li,  Yajun Li,  Shuang Wu,  Xinyue Tian,  Tongyu Tang,  Haibo Sun,  Chuan He, 
  • First Published: 03 May 2021
Research Article
Open Access

Fibrinogen Level Predicts Outcomes in Critically Ill Patients with Acute Exacerbation of Chronic Heart Failure

Zhongyuan Meng,  Yaxin Zhao,  Yan He, 
  • First Published: 30 April 2021
Research Article
Open Access

[Retracted] Environmental and Genetic Factors in the Pathogenesis of COPD in the Road-Working Population

Yumin Zhou,  Man Wang,  Weiyan Yang,  Jianjun Li,  Jialin Li,  Yueying Hu,  Wei Wang,  Chunli Che,  Hong Qi, 
  • First Published: 30 April 2021

Research Article
Open Access

Ethacrynic Acid Enhances the Antitumor Effects of Afatinib in EGFR/T790M-Mutated NSCLC by Inhibiting WNT/Beta-Catenin Pathway Activation

Xuehui Zhang,  Chaoyuan Huang,  Biyu Cui,  Yebin Pang,  Rong Liang,  Xiaoling Luo, 
  • First Published: 27 April 2021
Research Article
Open Access

Exploring the Relationship of Bone Turnover Markers and Bone Mineral Density in Community-Dwelling Postmenopausal Women

Xu Wei,  Yili Zhang,  Xinghua Xiang,  Menghua Sun,  Kai Sun,  Tao Han,  Baoyu Qi,  Yanming Xie,  Ranxing Zhang,  Liguo Zhu, 
  • First Published: 22 April 2021
Research Article
Open Access

Diagnostic Value of Circulating Progranulin and Its Receptor EphA2 in Predicting the Atheroma Burden in Patients with Coronary Artery Disease

Dan Tian,  Qing Qin,  Ruiyan Liu,  Zi Wang,  Xiaoyu Li,  Qing Xu,  Qianzhou Lv, 
  • First Published: 22 April 2021
Research Article
Open Access

[Retracted] Introducing V-Line as a New Strategy to Choose Surgical Corridor in Oblique Lumbar Interbody Fusion at the L5-S1 Segment

Wei Zhang,  Xing Du,  Yong Zhu,  Wei Luo,  Ben Wang,  Guanyin Jiang,  Yunsheng Ou, 
  • First Published: 22 April 2021

Research Article
Open Access

Prediction of COVID-19 with Computed Tomography Images using Hybrid Learning Techniques

Varalakshmi Perumal,  Vasumathi Narayanan,  Sakthi Jaya Sundar Rajasekar, 
  • First Published: 22 April 2021
Research Article
Open Access

[Retracted] Probiotic Supplement Preparation Relieves Test Anxiety by Regulating Intestinal Microbiota in College Students

Qi Qin,  Hui Liu,  Yulu Yang,  Yifei Wang,  Chaofei Xia,  Puyuan Tian,  Jing Wei,  Shengjie Li,  Tingtao Chen, 
  • First Published: 21 April 2021

Research Article
Open Access

Role of Annexin A1 in Squamous Cell Lung Cancer Progression

Omar Elakad,  Yuchan Li,  Natascha Gieser,  Sha Yao,  Stefan Küffer,  Marc Hinterthaner,  Bernhard C. Danner,  Alexander von Hammerstein-Equord,  Philipp Ströbel,  Hanibal Bohnenberger, 
  • First Published: 19 April 2021
Research Article
Open Access

Diagnostic Accuracy with Total Adenosine Deaminase as a Biomarker for Discriminating Pleural Transudates and Exudates in a Population-Based Cohort Study

Bernardo Henrique Ferraz Maranhão,  Cyro Teixeira da Silva Junior,  Jorge Luiz Barillo,  Carmem Lucia Teixeira de Castro,  Joeber Bernardo Soares de Souza,  Patricia Siqueira Silva,  Roberto Stirbulov, 
  • First Published: 12 April 2021
Research Article
Open Access

Application of Field-of-View Optimized and Constrained Undistorted Single Shot (FOCUS) with Intravoxel Incoherent Motion (IVIM) in 3T in Locally Advanced Rectal Cancer

Yipeng Cheng,  Huijie Jiang,  Hui Wang,  Qingchao Tang,  Tianyi Liu, 
  • First Published: 12 April 2021
Research Article
Open Access

Risk Factors and a Scoring System to Predict ARDS in Patients with COVID-19 Pneumonia in Korea: A Multicenter Cohort Study

Jun-Won Seo,  Seong Eun Kim,  Eun Young Choi,  Kyung Soo Hong,  Tae Hoon Oh,  Uh. Jin Kim,  Seung-Ji Kang,  Kyung-Hwa Park,  Sook-In Jung,  Da Young Kim,  Na Ra Yun,  Dong-Min Kim,  Hwa Pyung Kim,  Jian Hur,  Hee-Chang Jang, 
  • First Published: 09 April 2021
Research Article
Open Access

Prognostic Value of Pretreated Blood Inflammatory Markers in Patients with Bone Sarcoma: A Meta-Analysis

Min Jiang,  Shaowei Ma,  Zhongyan Hua,  Zhiying Zhao,  Song Gao, 
  • First Published: 09 April 2021
Research Article
Open Access

Transcriptome-Wide Gene Expression in a Murine Model of Ventilator-Induced Lung Injury

Zhao Li,  Guoshao Zhu,  Chen Zhou,  Hui Wang,  Le Yu,  Yunxin Xu,  Li Xu,  Qingxiu Wang, 
  • First Published: 08 April 2021
Research Article
Open Access

Handgrip Strength and Vitamin D as Predictors of Liver Fibrosis and Malnutrition in Chronic Hepatitis C Patients

Sami A. Gabr,  Ahmad H. Alghadir, 
  • First Published: 05 April 2021
Research Article
Open Access

Homocysteine Level and Risk of Hemorrhage in Brain Arteriovenous Malformations

Chaofan Zeng,  Fa Lin,  Peicong Ge,  Dong Zhang,  Shuo Wang,  Jizong Zhao, 
  • First Published: 31 March 2021
Research Article
Open Access

The Impact of Nerve Involvement on the Prognosis of Gastric Cancer Patients with Curative Gastrectomy: An International Multicenter Analysis

Kun Yang,  Yu-Qing Dan,  Yoon Young Choi,  Zong-Guang Zhou,  Woo Jin Hyung,  Jian-Kun Hu,  Sung Hoon Noh, 
  • First Published: 28 March 2021
Research Article
Open Access

The Age-AST-D Dimer (AAD) Regression Model Predicts Severe COVID-19 Disease

Fátima Higuera-de-la-Tijera,  Alfredo Servín-Caamaño,  Daniel Reyes-Herrera,  Argelia Flores-López,  Enrique J. A. Robiou-Vivero,  Felipe Martínez-Rivera,  Victor Galindo-Hernández,  Victor H. Rosales-Salyano,  Catalina Casillas-Suárez,  Oscar Chapa-Azuela,  Alfonso Chávez-Morales,  Billy Jiménez-Bobadilla,  María L. Hernández-Medel,  Benjamín Orozco-Zúñiga,  Jed R. Zacarías-Ezzat,  Santiago Camacho,  José L. Pérez-Hernández, 
  • First Published: 26 March 2021
Erratum
Open Access

Erratum to “Prognostic Role of Serum Amino Acids in Head and Neck Cancer”

Gabriella Cadoni,  Luca Giraldi,  Carlo Chiarla,  Jacopo Gervasoni,  Silvia Persichilli,  Aniello Primiano,  Stefano Settimi,  Jacopo Galli,  Gaetano Paludetti,  Dario Arzani,  Stefania Boccia,  Ivo Giovannini,  Giovanni Almadori, 
  • First Published: 24 March 2021

Research Article
Open Access

Anti-inflammatory Effects of Alcohol Are Associated with JNK-STAT3 Downregulation in an In Vitro Inflammation Model in HepG2 Cells

Katharina Mörs,  Ramona Sturm,  Jason-Alexander Hörauf,  Shinwan Kany,  Paola Cavalli,  Jazan Omari,  Maciej Powerski,  Alexey Surov,  Ingo Marzi,  Aleksander J. Nowak,  Borna Relja, 
  • First Published: 19 March 2021
Research Article
Open Access

A Novel Method for Accurate Quantification of Split Glomerular Filtration Rate Using Combination of Tc-99m-DTPA Renal Dynamic Imaging and Its Plasma Clearance

Xiaoxi Pang,  Fei Li,  Shan Huang,  Cheng’en Wang,  Tao Zhang,  Zihao Hu,  Hao Cheng,  Xinchen Tao,  Wenrui Chang, 
  • First Published: 15 March 2021
Research Article
Open Access

TNF-α Increase in a Cohort of Depressive Patients

Adrian Groh,  Kirsten Jahn,  Marc Walter,  Johannes Heck,  Ralf Lichtinghagen,  Eva Janke,  Schulze Westhoff M. L,  Maximillian Deest,  Helge Frieling,  Stefan Bleich,  Kai G. Kahl,  Annemarie Heberlein, 
  • First Published: 15 March 2021
Research Article
Open Access

Clinical Significance of Procalcitonin, C-Reactive Protein, and Interleukin-6 in Helping Guide the Antibiotic Use for Patients with Acute Exacerbations of Chronic Obstructive Pulmonary Disease

Wen Song,  Yue Wang,  Fengming Tian,  Liang Ge,  Xiaoqian Shang,  Qiang Zeng,  Ning Feng,  Jiahui Fan,  Jing Wang,  Xiumin Ma, 
  • First Published: 15 March 2021
Research Article
Open Access

The Genetic and Epigenetic Mechanisms Involved in Irreversible Pulp Neural Inflammation

Xiaoxi Xi,  Yihong Ma,  Yuzhen Xu,  Anthony Chukwunonso Ogbuehi,  Xiangqiong Liu,  Yupei Deng,  Junming Xi,  Haitong Pan,  Qian Lin,  Bo Li,  Wanchen Ning,  Xiao Jiang,  Hanluo Li,  Simin Li,  Xianda Hu, 
  • First Published: 09 March 2021
Research Article
Open Access

Validation of Normal P-Wave Parameters in a Large Unselected Pediatric Population of North-Western Romania: Results of the CARDIOPED Project

Gabriel Cismaru,  Cecilia Lazea,  Lucian Mureşan,  Gabriel Gusetu,  Radu Rosu,  Dana Pop,  Dumitru Zdrenghea,  Anca Daniela Farcaş,  Simona Sorana Căinap, 
  • First Published: 08 March 2021
Research Article
Open Access

Pentraxin 3 and the TyG Index as Two Novel Markers to Diagnose NAFLD in Children

Xiaolin Ye,  Jing Li,  Hongyu Wang,  Jie Wu, 
  • First Published: 08 March 2021
Research Article
Open Access

Prognostic Value of Peroxiredoxin-1 Expression in Patients with Solid Tumors: a Meta-Analysis of Cohort Study

Lianghe Jiao,  Jing Wei,  Jun Ye,  Chuanmeng Zhang, 
  • First Published: 04 March 2021
Research Article
Open Access

Validation of a One-Step Reverse Transcription-Droplet Digital PCR (RT-ddPCR) Approach to Detect and Quantify SARS-CoV-2 RNA in Nasopharyngeal Swabs

Catia Mio,  Adriana Cifù,  Stefania Marzinotto,  Barbara Marcon,  Corrado Pipan,  Giuseppe Damante,  Francesco Curcio, 
  • First Published: 04 March 2021
Research Article
Open Access

Upregulation of Serum miR-629 Predicts Poor Prognosis for Non-Small-Cell Lung Cancer

Fayong Liu,  Tianshui Li,  Ping Hu,  Li Dai, 
  • First Published: 03 March 2021
Research Article
Open Access

LncRNA Taurine Upregulated Gene 1 as a Potential Biomarker in the Clinicopathology and Prognosis of Multiple Malignant Tumors: A Meta-Analysis

Qi Huang,  Jingjing Wu,  Hui Wang,  Na Li,  Zhen Yang,  Mingjun Zhang, 
  • First Published: 02 March 2021
Research Article
Open Access

Identification of Prognostic and Therapeutic Biomarkers among FAM83 Family Members for Pancreatic Ductal Adenocarcinoma

Zuyi Ma,  Zixuan Zhou,  Hongkai Zhuang,  Zhenchong Li,  Zuguang Ma,  Bowen Huang,  Chunsheng Liu,  Yuanfeng Gong,  Yiping Zou,  Zehao Zheng,  Shanzhou Huang,  Chuanzhao Zhang,  Baohua Hou, 
  • First Published: 02 March 2021
Research Article
Open Access

Identification and Construction of a Long Noncoding RNA Prognostic Risk Model for Stomach Adenocarcinoma Patients

Zhiqiang Zha,  Peiling Zhang,  Dailing Li,  Guolong Liu,  Lin Lu, 
  • First Published: 24 February 2021
Research Article
Open Access

Golgi Phosphoprotein 3 Represents a Novel Tumor Marker for Gastric and Colorectal Cancers

Chun-Xiao Wang,  Hai-Bin Zhuang,  Ze-Sheng Shi,  Cheng-Zhi Qiu,  Zhi-Xiong Chen,  Long-Feng Tang, 
  • First Published: 24 February 2021
Research Article
Open Access

The Value of a Seven-Autoantibody Panel Combined with the Mayo Model in the Differential Diagnosis of Pulmonary Nodules

Zhougui Ling,  Jifei Chen,  Zhongwei Wen,  Xiaomou Wei,  Rui Su,  Zhenming Tang,  Zhuojun Hu, 
  • First Published: 20 February 2021
Research Article
Open Access

Serum Levels of BDNF in Patients with Adenoma and Colorectal Cancer

Zhe Wang,  Shuang Wang,  Yu Liu,  Shan Gao,  Yunqing Yu,  Zhaolan Hu, 
  • First Published: 12 February 2021
Research Article
Open Access

Next Generation Exome Sequencing of Pediatric Asthma Identifies Rare and Novel Variants in Candidate Genes

Neda M. Bogari,  Amr A. Amin,  Husni H. Rayes,  Ahmed Abdelmotelb,  Mohiuddin M. Taher,  Faisal A. Al-Allaf,  Abdellatif Bouazzaoui,  Luke O’Gorman,  John W. Holloway, 
  • First Published: 09 February 2021
Research Article
Open Access

The Diagnostic Value of Serum PIVKA-II Alone or in Combination with AFP in Chinese Hepatocellular Carcinoma Patients

Fei Xu,  Lulu Zhang,  Wenting He,  Di Song,  Xiaomeng Ji,  Jianyong Shao, 
  • First Published: 08 February 2021
Review Article
Open Access

Prevalence and Nonpharmacological Interventions for Sarcopenia among Cirrhotic Patients

Walid Kamal Abdelbasset,  Gopal Nambi,  Shereen H. Elsayed,  Samah A. Moawd,  Ahmed A. Ibrahim,  Anju Verma,  Sayed A. Tantawy,  Dalia M. Kamel,  Ayman K. Saleh,  Osama R. Aldhafian,  Naif Bin Nwihadh, 
  • First Published: 08 February 2021
Research Article
Open Access

Next-Generation Sequencing for Molecular Diagnosis of Cystic Fibrosis in a Brazilian Cohort

Amanda Cambraia,  Mario Campos Junior,  Verônica Marques Zembrzuski,  Ricardo Magrani Junqueira,  Pedro Hernán Cabello,  Giselda Maria Kalil de Cabello, 
  • First Published: 04 February 2021
Research Article
Open Access

Aberrant Hypermethylation-Mediated Suppression of PYCARD Is Extremely Frequent in Prostate Cancer with Gleason Score ≥ 7

Toshiya Miyauchi,  Masahiro Takahashi,  Koji Mitsuzuka,  Yuriko Saiki,  Teppei Okubo,  Paula M. Vertino,  Akiteru Goto,  Yoichi Arai,  Akira Horii,  Shinichi Fukushige, 
  • First Published: 04 February 2021
Review Article
Open Access

Assessment and Management of Cardiotoxicity in Hematologic Malignancies

Anca Bojan,  Tunde Torok-Vistai,  Andrada Parvu, 
  • First Published: 03 February 2021
Review Article
Open Access

Inflammatory Markers in Cerebrospinal Fluid from Patients with Hydrocephalus: A Systematic Literature Review

Sara Diana Lolansen,  Nina Rostgaard,  Eva Kjer Oernbo,  Marianne Juhler,  Anja Hviid Simonsen,  Nanna MacAulay, 
  • First Published: 03 February 2021
Research Article
Open Access

The Role, Function, and Mechanism of Long Intergenic Noncoding RNA1184 (linc01184) in Colorectal Cancer

Yan-Xia Sui,  Dong-Li Zhao,  Yan Yu,  Lin-Chuan Wang, 
  • First Published: 30 January 2021
Research Article
Open Access

VDR Gene Polymorphisms in Healthy Individuals with Family History of Premature Coronary Artery Disease

Martyna Fronczek,  Joanna Katarzyna Strzelczyk,  Tadeusz Osadnik,  Krzysztof Biernacki,  Zofia Ostrowska, 
  • First Published: 30 January 2021
Research Article
Open Access

Differentially Expressed Circular RNA Profile in an Intracranial Aneurysm Group Compared with a Healthy Control Group

Yonggang Ma,  Baoqing Zhang,  Dong Zhang,  Shuo Wang,  Maogui Li,  Jizong Zhao, 
  • First Published: 29 January 2021
Research Article
Open Access

Prognostic Value of Soluble Suppression of Tumorigenicity 2 in Chronic Kidney Disease Patients: A Meta-Analysis

Guangying Guo,  Aoran Huang,  Xin Huang,  Tianhua Xu,  Li Yao, 
  • First Published: 27 January 2021
Research Article
Open Access

Increased Expression of DNA2 Was Linked to Poor Prognosis in Breast Cancer

Yingyan Han,  Zeyu Zhang,  Zhi Wang,  Shujuan Sun, 
  • First Published: 27 January 2021
Research Article
Open Access

Inflammatory and Adipokine Status from Early to Midpregnancy in Arab Women and Its Associations with Gestational Diabetes Mellitus

Sara Al-Musharaf,  Shaun Sabico,  Syed Danish Hussain,  Fatima Al-Tawashi,  Haifa Bandar AlWaily,  Nasser M. Al-Daghri,  Philip McTernan, 
  • First Published: 23 January 2021
Review Article
Open Access

ECG Markers of Cardiovascular Toxicity in Adult and Pediatric Cancer Treatment

Ștefan Spînu,  Gabriel Cismaru,  Paul-Mihai Boarescu,  Sabina Istratoaie,  Alina Gabriela Negru,  Cecilia Lazea,  Simona Sorana Căinap,  Daniela Iacob,  Alin Ionut Grosu,  George Saraci,  Claudia Burz,  Andrei Cosmin Cismaru, 
  • First Published: 19 January 2021
Research Article
Open Access

Characteristics of Three Different Chemiluminescence Assays for Testing for SARS-CoV-2 Antibodies

Myriam C. Weber,  Martin Risch,  Sarah L. Thiel,  Kirsten Grossmann,  Susanne Nigg,  Nadia Wohlwend,  Thomas Lung,  Dorothea Hillmann,  Michael Ritzler,  Francesca Ferrara,  Susanna Bigler,  Konrad Egli,  Thomas Bodmer,  Mauro Imperiali,  Yacir Salimi,  Felix Fleisch,  Alexia Cusini,  Sonja Heer,  Harald Renz,  Matthias Paprotny,  Philipp Kohler,  Pietro Vernazza,  Lorenz Risch,  Christian R. Kahlert, 
  • First Published: 18 January 2021
Research Article
Open Access

Systemic Coagulation Markers Especially Fibrinogen Are Closely Associated with the Aggressiveness of Prostate Cancer in Patients Who Underwent Transrectal Ultrasound-Guided Prostate Biopsy

Fang-Ming Wang,  Nian-Zeng Xing, 
  • First Published: 18 January 2021
Research Article
Open Access

A 5-lncRNA Signature Associated with Smoking Predicts the Overall Survival of Patients with Muscle-Invasive Bladder Cancer

Haoyue Sheng,  Guiming Zhang,  Yongqiang Huang,  Lijiang Sun,  Guohai Shi,  Dingwei Ye, 
  • First Published: 18 January 2021
Editorial
Open Access

Role of the Gas6/TAM System as a Disease Marker and Potential Drug Target

Pier Paolo Sainaghi,  Mattia Bellan,  Alessandra Nerviani, 
  • First Published: 18 January 2021
Research Article
Open Access

A Risk Score Model Based on Nine Differentially Methylated mRNAs for Predicting Prognosis of Patients with Clear Cell Renal Cell Carcinoma

Jingmin Zhou,  Guanghua Liu,  Xingcheng Wu,  Zhien Zhou,  Jialin Li,  Zhigang Ji, 
  • First Published: 15 January 2021
Review Article
Open Access

Myokines and Heart Failure: Challenging Role in Adverse Cardiac Remodeling, Myopathy, and Clinical Outcomes

Alexander E. Berezin,  Alexander A. Berezin,  Michael Lichtenauer, 
  • First Published: 14 January 2021
Review Article
Open Access

Cardiotoxicity: A Major Setback in Childhood Leukemia Treatment

Diana R. Lazăr,  Anca D. Farcaş,  Cristina Blag,  Alexandra Neaga,  Mihnea T. Zdrenghea,  Călin Căinap,  Florin L. Lazăr,  Adrian Stef,  Simona S. Căinap, 
  • First Published: 08 January 2021
Research Article
Open Access

Identified GNGT1 and NMU as Combined Diagnosis Biomarker of Non-Small-Cell Lung Cancer Utilizing Bioinformatics and Logistic Regression

Jia-Jia Zhang,  Jiang Hong,  Yu-Shui Ma,  Yi Shi,  Dan-Dan Zhang,  Xiao-Li Yang,  Cheng-You Jia,  Yu-Zhen Yin,  Geng-Xi Jiang,  Da Fu,  Fei Yu, 
  • First Published: 06 January 2021
Research Article
Open Access

Correlation between Serum Bone Turnover Markers and Estimated Glomerular Filtration Rate in Chinese Patients with Diabetes

Xuming Zhu,  Ying Zhou,  Shanchao Hong,  Yifeng Xue,  Yubao Cui, 
  • First Published: 06 January 2021
Research Article
Open Access

Expression of Glutamine Metabolism-Related and Amino Acid Transporter Proteins in Adrenal Cortical Neoplasms and Pheochromocytomas

Hye Min Kim,  Ja Seung Koo, 
  • First Published: 06 January 2021