Highlights

• Diabetes can increase the severity of pulmonary tuberculosis.
• Patients with pulmonary tuberculosis and diabetes were more likely to have pulmonary cavities.
• Patients with pulmonary tuberculosis and diabetes may have higher rates of positive bacteriological tests.

Highlights

• Similar antibody response to COVID-19 inactivated vaccine between healthy controls (HCs) and patients with type 2 diabetes mellitus (T2DM) after a booster shot vaccine within 6 months.
• Patients with T2DM have reduced antibody response after receiving the third dose of the COVID-19 vaccine for more than 6 months.
• Both HCs and T2DM showed poor resistance against BA.4/5 due to the detected inhibition rates being lower than the positive threshold.

Highlights

• Preclinical data showed that dipeptidyl peptidase-4 inhibitors (DPP-4is) may prevent insulin-induced atherosclerosis.
• In patients treated with insulin for type 2 diabetes who underwent ≥2 serial coronary computed tomography angiographies(CCTA), a new obstructive coronary artery disease (OCAD) was less developed on the follow-up CCTA in those who received concomitant DPP-4is.
• A composite outcome of new OCAD, new implantation of coronary stent, or coronary bypass graft surgery was also lower in patients who received DPP-4is.

Highlights

• For the first time, we have examined the impact of microRNA on diabetic wounds at a cellular level.
• We have analyzed how a particular microRNA influences different types of cells, uncovering its function and mechanism.
• This study furthers the discovery of the clinical potential of diverse microRNAs by evaluating their distinct effects and mechanisms on multiple cell types.

Highlights

• Among 301 studies, diabetes mellitus was the most studied cardiometabolic risk factor.
• In the network meta-analysis, cerebrovascular disease had the highest impact (relative risk [RR] 1.69; 95% CI, 1.65–1.73) on COVID-19 outcomes compared to other cardiometabolic risk factors.
• For different combinations of risk factors, cardiovascular disease and diabetes mellitus combined (RR 6.98; 95% CI, 5.28–9.22) was more detrimental than others.

Highlights

• Both interleukin-10 levels and exosomal miR-let-7c-5p levels are correlated with cognitive function in patients with type 2 diabetes mellitus.
• There is a negative association between interleukin-10 levels and exosomal miR-let-7c-5p levels in the plasma of patients with type 2 diabetes mellitus.

Highlights

• We used data from the genome-wide association studies database and two-sample mendelian randomization method, we found that genetic evidence supporting that knee osteoarthritis is a potential risk factor for type 2 diabetes.

Highlights

• In this study, depression significantly increased the risk of incident type 2 diabetes and the risk increases as the degree of depression increases for a 5.2-year median follow-up.
• The results of this study suggest an age, sex, region and ethnicity difference in the relationship between depression and type 2 diabetes mellitus for Chinese populations.