Highlights

• Food insecurity is a major public health problem that highlights social disparities and negatively affects those with chronic diseases, including diabetes.
• Interventions targeting food insecurity in those with diabetes have shown little improvement in glycemic control despite improving food security status.
• This suggests a complex relationship between glycemic control and food insecurity that is likely mediated by many diverse socioeconomic factors.

Highlights

• Fructose raises uric acid, but the effect in diabetes is not known; people with type 2 diabetes have lower baseline uric acid than people without diabetes.
• Fructose loading leads to a blunted uric acid rise in people with type 2 diabetes; this effect is greater in obese people and those with poor glucose control.
• In contrast, glucose loading causes a fall in uric acid that is greater in diabetes patients; thus, people with diabetes have a different handling of uric acid than people without diabetes.

Highlights

• This is the first study to demonstrate that glycosylated hemoglobin (HbA1c) is an excellent marker for undiagnosed diabetes when diabetes is diagnosed before 24 gestational weeks.
• HbA1c ≥ 5.8% is suggested as cutoff to distinguish between undiagnosed diabetes and gestational diabetes.
• Definitive diagnosis should be done after delivery.

Highlights

• This is the first study to investigate the association of sleep efficiency with diabetes mellitus based on polysomnography data.
• Individuals with poor sleep efficiency have a higher proportion of diabetes mellitus.
• This community-based cross-sectional study found that poor sleep efficiency is associated with prevalence of diabetes mellitus in participants without sleep-disordered breathing.

Highlights

• Diabetic conditions induce compositional dysbiosis of the gut microbiota and impair gut barrier integrity.
• Diabetic conditions markedly downregulate the abundance of Faecalibacterium prausnitzii in the gut.
• Under diabetic conditions, microbial anti-inflammatory molecules from Faecalibacterium prausnitzii restore the gut barrier and ZO-1 expression possibly through the tight junction pathway.

Highlights

• We presented the first prediction score for nondiabetic renal disease (NDRD) in patients with type 2 diabetes and renal impairment and validated it in an independent cohort with high accuracy (0.85).
• The prediction model shows better diagnostic performance for predicting NDRD than variables alone, such as absence of diabetic retinopathy.

Highlights

• The GRK2 level elevated not only in the myocardium of diabetic mice with early stage of diabetic cardiomyopathy but also in the peripheral blood mononuclear cells of type 2 diabetic patients with the early stage of diabetic cardiomyopathy.
• The study findings suggested that the GRK2 was a potential biomarker for early diabetic cardiomyopathy.