• Issue

    Annals of Neurology: Volume 75, Issue 5

    619-801
    May 2014
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Editorials

A word to our authors

Clifford B. Saper MD, PhD, 
  • Pages: 619-620
  • First Published: 22 May 2014

Neurology's stake in foundational neuroscience research

Walter J. Koroshetz MD,  Story Landis PhD, 
  • Pages: 621-622
  • First Published: 23 April 2014
Free Access

What ethics integration looks like in neuroscience research

Stephen L. Hauser MD, 
  • Pages: 623-624
  • First Published: 07 May 2014

NeuroGenesis

Advice for clinician educators

Douglas J. Gelb MD, PhD, 
  • Pages: 625-630
  • First Published: 17 April 2014

Commentary

DEPDC5 does it all: Shared genetics for diverse epilepsy syndromes

Annapurna Poduri MD, MPH, 
  • Pages: 631-633
  • First Published: 20 April 2014

Research Articles

Reversible functional connectivity disturbances during transient global amnesia

Michael Peer MSc,  Mor Nitzan MSc,  Ilan Goldberg MD, PhD,  Judith Katz,  J. Moshe Gomori MD,  Tamir Ben-Hur MD, PhD,  Shahar Arzy MD, PhD, 
  • Pages: 634-643
  • First Published: 13 March 2014
Open Access

Cytosolic phospholipase A2 protein as a novel therapeutic target for spinal cord injury

Nai-Kui Liu MD, PhD,  Ling-Xiao Deng MD,  Yi Ping Zhang MD,  Qing-Bo Lu BA,  Xiao-Fei Wang PhD,  Jian-Guo Hu PhD,  Eddie Oakes BS,  Joseph V. Bonventre MD, PhD,  Christopher B. Shields MD,  Xiao-Ming Xu MD, PhD, 
  • Pages: 644-658
  • First Published: 13 March 2014

Hyperintense cortical signal on magnetic resonance imaging reflects focal leukocortical encephalitis and seizure risk in progressive multifocal leukoencephalopathy

Michael N. Khoury MD,  David C. Alsop PhD,  Shruti P. Agnihotri MD,  Rolf Pfannl MD,  Christian Wuthrich PhD,  Mai-Lan Ho MD,  David Hackney MD,  Long Ngo PhD,  Matthew P. Anderson MD, PhD,  Igor J. Koralnik MD, 
  • Pages: 659-669
  • First Published: 19 March 2014
Open Access

Streptococcus pneumoniae worsens cerebral ischemia via interleukin 1 and platelet glycoprotein Ibα

Ádám Dénes PhD,  Jesus M. Pradillo PhD,  Caroline Drake PhD,  Andrew Sharp PhD,  Peter Warn PhD,  Katie N. Murray MSc,  Bazaz Rohit PhD,  David H. Dockrell PhD,  Janet Chamberlain PhD,  Helen Casbolt PhD,  Sheila Francis PhD,  Bernadett Martinecz MSc,  Bernhard Nieswandt PhD,  Nancy J. Rothwell PhD,  Stuart M. Allan PhD, 
  • Pages: 670-683
  • First Published: 19 March 2014

Modulation of amyloid precursor protein expression reduces β-amyloid deposition in a mouse model

Ayodeji A. Asuni PhD,  Maitea Guridi MSc,  Joanna E. Pankiewicz MD, PhD,  Sandrine Sanchez PhD,  Martin J. Sadowski MD, PhD, 
  • Pages: 684-699
  • First Published: 31 March 2014

Surmounting retraining limits in Musicians' dystonia by transcranial stimulation

Shinichi Furuya PhD,  Michael A. Nitsche MD,  Walter Paulus MD,  Eckart Altenmüller MD, 
  • Pages: 700-707
  • First Published: 07 April 2014

Physical activity and amyotrophic lateral sclerosis: A European population-based case–control study

Elisabetta Pupillo DrPharm,  Paolo Messina DrStat,  Giorgia Giussani Biold,  Giancarlo Logroscino MD,  Stefano Zoccolella MD,  Adriano Chiò MD,  Andrea Calvo MD,  Massimo Corbo MD,  Christian Lunetta MD,  Benoit Marin MD,  Douglas Mitchell MD,  Orla Hardiman MD,  James Rooney MSc,  Zorica Stevic MD,  Monica Bandettini di Poggio MD,  Massimiliano Filosto MD,  Maria Sofia Cotelli MD,  Michele Perini MD,  Nilo Riva MD,  Lucio Tremolizzo MD,  Eugenio Vitelli MD,  Danira Damiani DrBT,  Ettore Beghi MD,  the EURALS Consortium , 
  • Pages: 708-716
  • First Published: 05 April 2014

Cortical interneuron loss and symptom heterogeneity in Huntington disease

Eric H. Kim PhD,  Doris C. V. Thu PhD,  Lynette J. Tippett PhD,  Dorothy E. Oorschot PhD,  Virginia M. Hogg MA,  Richard Roxburgh MD, PhD,  Beth J. Synek MD,  Henry J. Waldvogel PhD,  Richard L. M. Faull MD, PhD, DSc, 
  • Pages: 717-727
  • First Published: 26 April 2014

Pathologic heterogeneity persists in early active multiple sclerosis lesions

Imke Metz MD,  Stephen D. Weigand MS,  Bogdan F. G. Popescu PhD,  Josa M. Frischer PhD,  Joseph E. Parisi MD,  Yong Guo MD,  Hans Lassmann MD,  Wolfgang Brück MD,  Claudia F. Lucchinetti MD, 
  • Pages: 728-738
  • First Published: 26 April 2014

Ultraviolet B light attenuates the systemic immune response in central nervous system autoimmunity

Johanna Breuer MSc,  Nicholas Schwab PhD,  Tilman Schneider-Hohendorf PhD,  Martin Marziniak MD,  Hema Mohan PhD,  Urvashi Bhatia MSc,  Catharina C. Gross PhD,  Björn E. Clausen PhD,  Carsten Weishaupt MD,  Thomas A. Luger MD,  Sven G. Meuth MD, PhD,  Karin Loser PhD,  Heinz Wiendl MD, 
  • Pages: 739-758
  • First Published: 27 April 2014

Linking MRI postprocessing with magnetic source imaging in MRI-negative epilepsy

Zhong I. Wang PhD,  Andreas V. Alexopoulos MD, MPH,  Stephen E. Jones MD, PhD,  Imad M. Najm MD,  Aleksandar Ristic MD,  Chong Wong MD, PhD,  Richard Prayson MD,  Felix Schneider MD,  Yosuke Kakisaka MD, PhD,  Shuang Wang MD,  William Bingaman MD,  Jorge A. Gonzalez-Martinez MD, PhD,  Richard C. Burgess MD, PhD, 
  • Pages: 759-770
  • First Published: 29 April 2014

Nonconvulsive seizures in subarachnoid hemorrhage link inflammation and outcome

Jan Claassen MD, PhD,  David Albers PhD,  J. Michael Schmidt PhD,  Gian Marco De Marchis MD,  Deborah Pugin MD,  Christina Maria Falo PhD,  Stephan A. Mayer MD,  Serge Cremers PhD,  Sachin Agarwal MD,  Mitchell S. V. Elkind MD, MS,  E. Sander Connolly MD,  Vanja Dukic PhD,  George Hripcsak MD,  Neeraj Badjatia MD, 
  • Pages: 771-781
  • First Published: 27 April 2014

Brief Communications

Mutations in mammalian target of rapamycin regulator DEPDC5 cause focal epilepsy with brain malformations

Ingrid E. Scheffer MB, BS, PhD,  Sarah E. Heron BSc, PhD,  Brigid M. Regan BSc,  Simone Mandelstam MB, ChB,  Douglas E. Crompton MBBS, PhD,  Bree L. Hodgson Dip Biomed Sci,  Laura Licchetta MD,  Federica Provini MD, PhD,  Francesca Bisulli MD, PhD,  Lata Vadlamudi MB, BS, PhD,  Jozef Gecz PhD,  Alan Connelly PhD,  Paolo Tinuper MD,  Michael G. Ricos BSc, PhD,  Samuel F. Berkovic MD, FRS,  Leanne M. Dibbens BSc, PhD, 
  • Pages: 782-787
  • First Published: 01 March 2014

DEPDC5 mutations in genetic focal epilepsies of childhood

Dennis Lal PhD,  Eva M. Reinthaler MS,  Julian Schubert MSc,  Hiltrud Muhle MD,  Erik Riesch MD,  Gerhard Kluger MD,  Kamel Jabbari PhD,  Amit Kawalia MSc,  Christine Bäumel MD,  Hans Holthausen MD,  Andreas Hahn MD,  Martha Feucht MD,  Birgit Neophytou MD,  Edda Haberlandt MD,  Felicitas Becker MD,  Janine Altmüller MD,  Holger Thiele MD,  Johannes R. Lemke MD,  Holger Lerche MD,  Peter Nürnberg PhD,  Thomas Sander MD,  Yvonne Weber MD,  Fritz Zimprich MD, PhD,  Bernd A. Neubauer MD, 
  • Pages: 788-792
  • First Published: 01 March 2014

UBQLN2 mutation causing heterogeneous X-linked dominant neurodegeneration

Akl C. Fahed MD,  Barbara McDonough BS,  Cynthia M. Gouvion BS,  Kathy L. Newell MD,  Leon S. Dure MD,  Martina Bebin MD, MPA,  Alexander G. Bick BS,  Jonathan G. Seidman PhD,  Donald H. Harter MD,  Christine E. Seidman MD, 
  • Pages: 793-798
  • First Published: 26 April 2014

Letter/Replies

Copper deficiency clinical case conference: In defense of checklists

Pasquale F. Finelli MD,  Andrew L. McCabe, 
  • Page: 799
  • First Published: 19 March 2014

Reply

Martin A. Samuels MD, 
  • Page: 799
  • First Published: 19 March 2014

Gender as a disease modifier in neurofibromatosis type 1 optic pathway glioma

Michael J. Fisher MD,  Michael Loguidice MD,  David H. Gutmann MD, PhD,  Robert Listernick MD,  Rosalie E. Ferner MD,  Nicole J. Ullrich MD, PhD,  Roger J. Packer MD,  Uri Tabori MD,  Robert O. Hoffman MD,  Simone L. Ardern-Holmes MD,  Trent R. Hummel MD,  Darren R. Hargrave MD,  Eric Bouffet MD,  Joel Charrow MD,  Larissa T. Bilaniuk MD,  Laura J. Balcer MD, MSCE,  Lucy D'Agostino McGowan MS,  Grant T. Liu MD, 
  • Pages: 799-800
  • First Published: 17 April 2014

Reply

Kelly A. Diggs-Andrews PhD,  Jacquelyn A. Brown PhD,  Scott M. Gianino MS,  Lucy D'Agostino McGowan MS,  Joshua B. Rubin MD, PhD,  David F. Wozniak PhD,  David H. Gutmann MD, PhD, 
  • Pages: 800-801
  • First Published: 18 April 2014