• Issue

    Annals of Neurology: Volume 75, Issue 4

    467-618
    April 2014
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Editorial

The view from here: The eighth year of RomneyCare

Clifford B. Saper MD, PhD, 
  • Pages: 467-468
  • First Published: 05 May 2014

Review

Brain injury in premature neonates: A primary cerebral dysmaturation disorder?

Stephen A. Back MD, PhD,  Steven P. Miller MDCM, MAS, 
  • Pages: 469-486
  • First Published: 11 March 2014

Neurogenesis

In the beginning: How medical students choose (or do not choose) neurology

Kelley A. Humbert BA,  Bernard S. Chang MD, 
  • Pages: 487-489
  • First Published: 11 March 2014

Commentary

Glucose, acid, and aspartate: Friends and foes of the axon

Raymond A. Swanson MD, 
  • Pages: 490-491
  • First Published: 23 November 2013

Research Articles

Novel hypoglycemic injury mechanism: N-methyl-D-aspartate receptor–mediated white matter damage

Xin Yang MD, PhD,  Margaret A. Hamner PhD,  Angus M. Brown PhD,  Richard D. Evans PhD,  Zu-Cheng Ye PhD,  Shengdi Chen MD, PhD,  Bruce R. Ransom MD, PhD, 
  • Pages: 492-507
  • First Published: 16 November 2013

Prenatal cerebral ischemia triggers dysmaturation of caudate projection neurons

Evelyn McClendon PhD,  Kevin Chen BS,  Xi Gong MD,  Elica Sharifnia BA,  Matthew Hagen BA,  Victor Cai,  Daniel C. Shaver BA,  Art Riddle PhD,  Justin M. Dean PhD,  Alistair J. Gunn MBChB, PhD,  Claudia Mohr PhD,  Joshua S. Kaplan BA,  David J. Rossi PhD,  Christopher D. Kroenke PhD,  A. Roger Hohimer PhD,  Stephen A. Back MD, PhD, 
  • Pages: 508-524
  • First Published: 03 January 2014
Open Access

Genetics of low spinal muscular atrophy carrier frequency in sub-Saharan Africa

Modibo Sangaré MD,  Brant Hendrickson MSc,  Hammadoun Ali Sango MD,  Kelian Chen BS,  Jonathan Nofziger BA,  Abdelbasset Amara MSc, PhD,  Amalia Dutra PhD,  Alice B. Schindler MSc, CGC,  Aldiouma Guindo PharmD, PhD,  Mahamadou Traoré MSc, PhD,  George Harmison MS,  Evgenia Pak MD,  Fatoumata N'Go Yaro MD,  Katherine Bricceno PhD,  Christopher Grunseich MD,  Guibin Chen MS,  Manfred Boehm MD,  Kristen Zukosky BA,  Nouhoum Bocoum MD,  Katherine G. Meilleur PhD,  Fatoumata Daou PharmD,  Koumba Bagayogo MD,  Yaya Ibrahim Coulibaly MD,  Mahamadou Diakité PharmD, PhD,  Michael P. Fay PhD,  Hee-Suk Lee PhD,  Ali Saad MD, PhD,  Moez Gribaa MD, PhD,  Andrew B. Singleton PhD,  Youssoufa Maiga MD,  Sungyoung Auh PhD,  Guida Landouré MD, PhD,  Rick M. Fairhurst MD, PhD,  Barrington G. Burnett PhD,  Thomas Scholl PhD,  Kenneth H. Fischbeck MD, 
  • Pages: 525-532
  • First Published: 06 February 2014

Unmyelinated axon loss with postnatal hypertonia after fetal hypoxia

Alexander Drobyshevsky PhD,  Rugang Jiang PhD,  Laixiang Lin PhD,  Matthew Derrick MD,  Kehuan Luo MD,  Stephen A. Back MD, PhD,  Sidhartha Tan MD, 
  • Pages: 533-541
  • First Published: 06 February 2014

Gain-of-function ADCY5 mutations in familial dyskinesia with facial myokymia

Ying-Zhang Chen MD, PhD,  Jennifer R. Friedman MD,  Dong-Hui Chen MD, PhD,  Guy C.-K. Chan PhD,  Cinnamon S. Bloss PhD,  Fuki M. Hisama MD,  Sarah E. Topol RN,  Andrew R. Carson PhD,  Phillip H. Pham BS,  Emily S. Bonkowski BS,  Erick R. Scott MD,  Janel K. Lee BS,  Guangfa Zhang PhD,  Glenn Oliveira BS,  Jian Xu PhD,  Ashley A. Scott-Van Zeeland PhD,  Qi Chen PhD,  Samuel Levy PhD,  Eric J. Topol MD,  Daniel Storm PhD,  Phillip D. Swanson MD, PhD,  Thomas D. Bird MD,  Nicholas J. Schork PhD,  Wendy H. Raskind MD, PhD,  Ali Torkamani PhD, 
  • Pages: 542-549
  • First Published: 15 February 2014

A novel prodrug-based strategy to increase effects of bumetanide in epilepsy

Kathrin Töllner DVM, PhD,  Claudia Brandt PhD,  Manuel Töpfer DVM, PhD,  Gerda Brunhofer PhD,  Thomas Erker PhD,  Mario Gabriel DI(FH),  Peter W. Feit PhD,  Jenna Lindfors BSc,  Kai Kaila PhD,  Wolfgang Löscher DVM, PhD, 
  • Pages: 550-562
  • First Published: 25 February 2014

Sex modifies the APOE-related risk of developing Alzheimer disease

Andre Altmann PhD,  Lu Tian ScD,  Victor W. Henderson MD,  Michael D. Greicius MD,  for the Alzheimer's Disease Neuroimaging Initiative Investigators , 
  • Pages: 563-573
  • First Published: 13 March 2014

Value of serum nonceruloplasmin copper for prediction of mild cognitive impairment conversion to Alzheimer disease

Rosanna Squitti PhD,  Roberta Ghidoni PhD,  Mariacristina Siotto PhD,  Mariacarla Ventriglia PhD,  Luisa Benussi PhD,  Anna Paterlini PhD,  Mariachiara Magri PhD,  Giuliano Binetti MD,  Emanuele Cassetta MD,  Deborah Caprara PhD,  Fabrizio Vernieri MD,  Paolo M. Rossini MD,  Patrizio Pasqualetti PhD, 
  • Pages: 574-580
  • First Published: 13 March 2014

KCNT1 gain of function in 2 epilepsy phenotypes is reversed by quinidine

Carol J. Milligan PhD,  Melody Li BSc,  Elena V. Gazina PhD,  Sarah E. Heron PhD,  Umesh Nair BSc,  Chantel Trager BSc,  Christopher A. Reid PhD,  Anu Venkat MD,  Donald P. Younkin MD,  Dennis J. Dlugos MD,  Slavé Petrovski PhD,  David B. Goldstein PhD,  Leanne M. Dibbens PhD,  Ingrid E. Scheffer MBBS, PhD,  Samuel F. Berkovic MD,  Steven Petrou PhD, 
  • Pages: 581-590
  • First Published: 03 March 2014

Brief Communications

Open Access

Botulinum toxin-a treatment reduces human mechanical pain sensitivity and mechanotransduction

Kathryn Paterson MRes,  Stéphane Lolignier PhD,  John N. Wood FRS,  Stephen B. McMahon FMedSci,  David L. H. Bennett FRCP, 
  • Pages: 591-596
  • First Published: 18 February 2014

Mild to moderate Alzheimer dementia with insufficient neuropathological changes

Alberto Serrano-Pozo MD, PhD,  Jing Qian PhD,  Sarah E. Monsell MS,  Deborah Blacker MD, ScD,  Teresa Gómez-Isla MD, PhD,  Rebecca A. Betensky PhD,  John H. Growdon MD,  Keith A. Johnson MD,  Matthew P. Frosch MD, PhD,  Reisa A. Sperling MD, MMSc,  Bradley T. Hyman MD, PhD, 
  • Pages: 597-601
  • First Published: 01 March 2014

A novel mechanism for cyclic adenosine monophosphate–mediated memory formation: Role of amyloid beta

Roberta Ricciarelli PhD,  Daniela Puzzo MD, PhD,  Olga Bruno PhD,  Elisa Canepa PhD,  Elena Gardella BSc,  Daniela Rivera BSc,  Lucia Privitera PhD,  Cinzia Domenicotti PhD,  Barbara Marengo PhD,  Umberto Maria Marinari MD,  Agostino Palmeri MD, PhD,  Maria Adelaide Pronzato BSc,  Ottavio Arancio MD, PhD,  Ernesto Fedele BSc, 
  • Pages: 602-607
  • First Published: 04 March 2014

Pathology of inherited manganese transporter deficiency

Mirna Lechpammer MD, PhD,  Michael S. Clegg PhD,  Zukhrofi Muzar MD,  Philip A. Huebner,  Lee-Way Jin MD, PhD,  Sidney M. Gospe Jr MD, PhD, 
  • Pages: 608-612
  • First Published: 06 March 2014

Letters/Replies

Mediterranean diet: Relationship with anxiety and depression

Guglielmo M. Trovato MD,  Daniela Catalano MD,  Giuseppe Fabio Martines MD,  Patrizia Pace PhD,  Francesca M. Trovato MD, 
  • Page: 613
  • First Published: 08 August 2013

Reply

Theodora Psaltopoulou PhD,  Theodoros N. Sergentanis MD,  Demosthenes B. Panagiotakos PhD,  Ioannis N. Sergentanis MD,  Rena Kosti PhD,  Nikolaos Scarmeas MD, MSc, PhD, 
  • Page: 614
  • First Published: 08 August 2013

Viral infection and focal cortical dysplasia

Shiyong Liu MD, PhD,  Linxiang Lu MD,  Xin Cheng MD,  Guangzheng Xu MD, PhD,  Hui Yang MD, PhD, 
  • Pages: 614-616
  • First Published: 04 October 2013

Reply

Peter B. Crino MD, PhD, 
  • Pages: 616-617
  • First Published: 04 October 2013

Genetic influences and neuropathological sequelae of repetitive brain injury

Daniel T. Laskowitz MD,  Hana N. Dawson PhD, 
  • Pages: 617-618
  • First Published: 15 November 2013

Reply

Rebekah Mannix MD, MPH,  William P. Meehan MD,  Mel Feany MD, PhD,  Patricia Ellen Grant MD,  Joseph Mandeville PhD,  David L. Kaplan PhD,  Michael Whalen MD, 
  • Page: 618
  • First Published: 16 November 2013