European Journal of Immunology: Vol 40, No 12

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European Journal of Immunology

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European Journal of Immunology: Volume 40, Issue 12

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Cover Picture

Cover Picture: Eur. J. Immunol. 12/10

Editorial Board

Editorial Board: Eur. J. Immunol. 12/10

Editorial

Editorial

Contents

Contents – Eur. J. Immunol. 12/10

In this issue

In this issue

News and EFIS

Professor Emeritus Maxime Seligmann (1927–2010)

Meeting Report

Addressing tumour tolerance to improve cancer immunotherapy

Highlights

Mini-Review

The IgH 3′ regulatory region and its implication in lymphomagenesis

Commentaries

The transient nature of the Th17 phenotype†

The growing diversity and spectrum of action of myeloid-derived suppressor cells

Treg and T-effector cells in autoimmune CNS inflammation: A delicate balance, easily disturbed

Frontline

Efficient Treg depletion induces T-cell infiltration and rejection of large tumors

Genetic proof for the transient nature of the Th17 phenotype

IL-1β regulates a novel myeloid-derived suppressor cell subset that impairs NK cell development and function

Cannabinoid receptor activation leads to massive mobilization of myeloid-derived suppressor cells with potent immunosuppressive properties

Cellular immune response

Short Communications

Caspase 3 is not essential for the induction of anergy or multiple pathways of CD8+ T-cell death

Research Article

Constant TCR triggering suggests that the TCR expressed on intestinal intraepithelial γδ T cells is functional in vivo

Effects of IFN-α as a signal-3 cytokine on human naïve and antigen-experienced CD8+ T cells

Reduced Treg frequency in LFA-1-deficient mice allows enhanced T effector differentiation and pathology in EAE

Enhanced responsiveness to T-cell help causes loss of B-lymphocyte tolerance to a β-cell neo-self-antigen in type 1 diabetes prone NOD mice

Robust genital gag-specific CD8+ T-cell responses in mice upon intramuscular immunization with simian adenoviral vectors expressing HIV-1-gag

Immunoproteasomes are essential for survival and expansion of T cells in virus-infected mice

Immunity to infection

Short Communication

T cells acquire cell surface determinants of APC via in vivo trogocytosis during viral infections

Research Article

Contrasting roles of macrophages and dendritic cells in controlling initial pulmonary Brucella infection

Short Communication

Memory-like IFN-γ response by NK cells following malaria infection reveals the crucial role of T cells in NK cell activation by P. falciparum

Immunomodulation

Research Article

CD4+CD25+ Treg regulate the contribution of CD8+ T-cell subsets in repopulation of the lymphopenic environment

Endogenous estrogens, through estrogen receptor α, constrain autoimmune inflammation in female mice by limiting CD4+ T-cell homing into the CNS

Transplantation of autoimmune regulator-encoding bone marrow cells delays the onset of experimental autoimmune encephalomyelitis

Targeting SIRP-α protects from type 2-driven allergic airway inflammation

Innate immunity

Research Article

NOD1 and NOD2 regulation of pulmonary innate immunity to Legionella pneumophila

Short Communication

TLR5 or NLRC4 is necessary and sufficient for promotion of humoral immunity by flagellin

Research Article

The activating rat Ly49s5 receptor responds to increased levels of MHC class Ib molecules on Listeria monocytogenes-infected enteric epithelial cells

Molecular immunology

Research Article

SWAP-70 controls formation of the splenic marginal zone through regulating T1B-cell differentiation

TLR-mediated signaling pathways circumvent the requirement for DAP12 in mast cells for the induction of inflammatory mediator release

Functional involvement of Daxx in gp130-mediated cell growth and survival in BaF3 cells

Clinical immunology

Research Article

Regulatory T cells exhibit enhanced migratory characteristics, a feature impaired in patients with multiple sclerosis

Technical comment

Generation of TRAIL-receptor 1-specific human monoclonal Ab by a combination of immunospot array assay on a chip and human Ab-producing mice

Acknowledgements

Acknowledgements

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The transient nature of the Th17 phenotype ^†

Caspase 3 is not essential for the induction of anergy or multiple pathways of CD8⁺ T-cell death

Effects of IFN-α as a signal-3 cytokine on human naïve and antigen-experienced CD8⁺ T cells

Robust genital gag-specific CD8⁺ T-cell responses in mice upon intramuscular immunization with simian adenoviral vectors expressing HIV-1-gag

CD4⁺CD25⁺ Treg regulate the contribution of CD8⁺ T-cell subsets in repopulation of the lymphopenic environment

Endogenous estrogens, through estrogen receptor α, constrain autoimmune inflammation in female mice by limiting CD4⁺ T-cell homing into the CNS