European Journal of Immunology: Vol 41, No 1

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European Journal of Immunology

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European Journal of Immunology: Volume 41, Issue 1

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Cover Picture

Cover Picture: Eur. J. Immunol. 1/11

Editorial Board

Editorial Board: Eur. J. Immunol. 1/11

Contents

Contents – Eur. J. Immunol. 1/11

In this issue

In this issue

News and EFIS

Robert Koch prizes: Honouring researchers in immunology and infectious diseases

Highlights

Review

Contrasting models for the roles of Aire in the differentiation program of epithelial cells in the thymic medulla

Guiding the “misguided” – functional conditioning of dendritic cells for the DC-based immunotherapy against tumours

Commentary

γδ T cells develop, respond and survive – with a little help from CD27

Frontline

TLR5 functions as an endocytic receptor to enhance flagellin-specific adaptive immunity

Antigen processing

Short Communication

Differences in the production of spliced antigenic peptides by the standard proteasome and the immunoproteasome

Cellular immune response

Research Article

IL-27 increases the proliferation and effector functions of human naïve CD8+ T lymphocytes and promotes their development into Tc1 cells

T-bet-mediated differentiation of the activated CD8+ T cell

Galectin-9 ameliorates acute GVH disease through the induction of T-cell apoptosis

Rhoh deficiency reduces peripheral T-cell function and attenuates allogenic transplant rejection

Short Communication

Tertiary lymphoid organs in renal allografts can be associated with donor-specific tolerance rather than rejection

Immunity to infection

Research Article

Selection of escape mutant by HLA-C-restricted HIV-1 Pol-specific cytotoxic T lymphocytes carrying strong ability to suppress HIV-1 replication

CD4+ T-cell immunity to the Burkholderia pseudomallei ABC transporter LolC in melioidosis

Cystatin cures visceral leishmaniasis by NF-κB-mediated proinflammatory response through co-ordination of TLR/MyD88 signaling with p105-Tpl2-ERK pathway

Immunomodulation

Research Article

Generation of human Th1-like regulatory CD4+ T cells by an intrinsic IFN-γ- and T-bet-dependent pathway

Estrogen receptor-β ligand treatment modulates dendritic cells in the target organ during autoimmune demyelinating disease

Measles virus modulates dendritic cell/T-cell communication at the level of plexinA1/neuropilin-1 recruitment and activity

Short Communication

TNF superfamily member 13, APRIL, inhibits allergic lung inflammation

Innate immunity

Research Article

Borrelia species induce inflammasome activation and IL-17 production through a caspase-1-dependent mechanism

Negative regulation of Toll-like receptor signaling plays an essential role in homeostasis of the intestine

Molecular immunology

Short Communication

CD70–CD27 interactions provide survival and proliferative signals that regulate T cell receptor-driven activation of human γδ peripheral blood lymphocytes

Research Article

Overexpression of phospholipase Cε in keratinocytes upregulates cytokine expression and causes dermatitis with acanthosis and T-cell infiltration

Carbohydrate recognition and complement activation by rat ficolin-B

Novel splice variants of human IKKε negatively regulate IKKε-induced IRF3 and NF-kB activation

Clinical immunology

Research Article

Increased IL-17A secretion in response to Candida albicans in autoimmune polyendocrine syndrome type 1 and its animal model

Short Communication

IL-17 production by γδ T cells is important for the antitumor effect of Mycobacterium bovis bacillus Calmette-Guérin treatment against bladder cancer

Technical comments

Contamination with recombinant IFN accounts for the unexpected stimulatory properties of commonly used IFN-blocking antibodies

Improved detection of latent Mycobacterium tuberculosis infection in HIV-1 seropositive individuals using cultured cellular assays

Correction

Correction: Influence of human cytomegalovirus infection on the NK cell receptor repertoire in children

This article corrects the following:

Influence of human cytomegalovirus infection on the NK cell receptor repertoire in children

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IL-27 increases the proliferation and effector functions of human naïve CD8⁺ T lymphocytes and promotes their development into Tc1 cells

T-bet-mediated differentiation of the activated CD8⁺ T cell

CD4⁺ T-cell immunity to the Burkholderia pseudomallei ABC transporter LolC in melioidosis

Generation of human Th1-like regulatory CD4⁺ T cells by an intrinsic IFN-γ- and T-bet-dependent pathway