• Issue

    Aging Cell: Volume 9, Issue 5

    653-931
    October 2010
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Reviews

Role of shelterin in cancer and aging

Paula Martínez,  Maria A. Blasco, 
  • Pages: 653-666
  • First Published: 16 September 2010
Open Access

Fat tissue, aging, and cellular senescence

Tamara Tchkonia,  Dean E. Morbeck,  Thomas Von Zglinicki,  Jan Van Deursen,  Joseph Lustgarten,  Heidi Scrable,  Sundeep Khosla,  Michael D. Jensen,  James L. Kirkland, 
  • Pages: 667-684
  • First Published: 16 September 2010

Original Articles

Effects of aging and gender on the spatial organization of nuclei in single human skeletal muscle cells

Alexander Cristea,  Rizwan Qaisar,  Patrick K. Edlund,  Joakim Lindblad,  Ewert Bengtsson,  Lars Larsson, 
  • Pages: 685-697
  • First Published: 16 September 2010

HRAS1 and LASS1 with APOE are associated with human longevity and healthy aging

S. Michal Jazwinski,  Sangkyu Kim,  Jianliang Dai,  Li Li,  Xiuhua Bi,  James C. Jiang,  Jonathan Arnold,  Mark A. Batzer,  Jerilyn A. Walker,  David A. Welsh,  Christina M. Lefante,  Julia Volaufova,  Leann Myers,  L. Joseph Su,  Dorothy B. Hausman,  Michael V. Miceli,  Eric Ravussin,  Leonard W. Poon,  Katie E. Cherry,  Michael A. Welsch,  for the Georgia Centenarian Study and the Louisiana Healthy Aging Study , 
  • Pages: 698-708
  • First Published: 16 September 2010

Reversal of aging-associated hippocampal synaptic plasticity deficits by reductants via regulation of thiol redox and NMDA receptor function

Yuan-Jian Yang,  Peng-Fei Wu,  Li-Hong Long,  Dan-Fang Yu,  Wen-Ning Wu,  Zhuang-Li Hu,  Hui Fu,  Na Xie,  You Jin,  Lan Ni,  Jian-Zhi Wang,  Fang Wang,  Jian-Guo Chen, 
  • Pages: 709-721
  • First Published: 16 September 2010

Reduction in glutamate uptake is associated with extrasynaptic NMDA and metabotropic glutamate receptor activation at the hippocampal CA1 synapse of aged rats

Brigitte Potier,  Jean-Marie Billard,  Sylvain Rivière,  Pierre-Marie Sinet,  Isabelle Denis,  Gaelle Champeil-Potokar,  Barbara Grintal,  Anne Jouvenceau,  Melanie Kollen,  Patrick Dutar, 
  • Pages: 722-735
  • First Published: 16 September 2010

p16INK4a-mediated suppression of telomerase in normal and malignant human breast cells

Alexey V. Bazarov,  Marjolein Van Sluis,  William C. Hines,  Ekaterina Bassett,  Alain Beliveau,  Eric Campeau,  Rituparna Mukhopadhyay,  Won Jae Lee,  Sonya Melodyev,  Yuri Zaslavsky,  Leonard Lee,  Francis Rodier,  Agustin Chicas,  Scott W. Lowe,  Jean Benhattar,  Bing Ren,  Judith Campisi,  Paul Yaswen, 
  • Pages: 736-746
  • First Published: 16 September 2010

BTG2 antagonizes Pin1 in response to mitogens and telomere disruption during replicative senescence

Keith Wheaton,  Jennifer Muir,  Weili Ma,  Samuel Benchimol, 
  • Pages: 747-760
  • First Published: 16 September 2010

Cyclophilin D links programmed cell death and organismal aging in Podospora anserina

Diana Brust,  Bertram Daum,  Christine Breunig,  Andrea Hamann,  Werner Kühlbrandt,  Heinz D. Osiewacz, 
  • Pages: 761-775
  • First Published: 16 September 2010

Aldose Reductase and AGE–RAGE pathways: central roles in the pathogenesis of vascular dysfunction in aging rats

Kellie McCormick Hallam,  Qing Li,  Radha Ananthakrishnan,  Anastasia Kalea,  Yu S. Zou,  Srinivasan Vedantham,  Ann Marie Schmidt,  Shi Fang Yan,  Ravichandran Ramasamy, 
  • Pages: 776-784
  • First Published: 16 September 2010

Partial restoration of T-cell function in aged mice by in vitro blockade of the PD-1/ PD-L1 pathway

Celine S. Lages,  Ian Lewkowich,  Alyssa Sproles,  Marsha Wills-Karp,  Claire Chougnet, 
  • Pages: 785-798
  • First Published: 16 September 2010

Inhibition of apoptosis by progesterone in cardiomyocytes

Stephen Morrissy,  Beibei Xu,  David Aguilar,  Jack Zhang,  Qin M. Chen, 
  • Pages: 799-809
  • First Published: 18 August 2010

Downregulation of lamin A by tumor suppressor AIMP3/p18 leads to a progeroid phenotype in mice

Young Sun Oh,  Dae Gyu Kim,  Gyuyoup Kim,  Eung-Chil Choi,  Brian K. Kennedy,  Yousin Suh,  Bum Joon Park,  Sunghoon Kim, 
  • Pages: 810-822
  • First Published: 18 August 2010

Identification of genetic determinants of IGF-1 levels and longevity among mouse inbred strains

Magalie S. Leduc,  Rachael S. Hageman,  Qingying Meng,  Ricardo A. Verdugo,  Shirng-Wern Tsaih,  Gary A. Churchill,  Beverly Paigen,  Rong Yuan, 
  • Pages: 823-836
  • First Published: 16 September 2010

Differential regulation of NMDA receptor function by DJ-1 and PINK1

Ning Chang,  Lijun Li,  Rong Hu,  Yuexin Shan,  Baosong Liu,  Lei Li,  Hanbin Wang,  Hua Feng,  Dianshi Wang,  Carol Cheung,  Mingxia Liao,  Qi Wan, 
  • Pages: 837-850
  • First Published: 16 September 2010

Decreased oxidative stress and greater bone anabolism in the aged, when compared to the young, murine skeleton with parathyroid hormone administration

Robert L. Jilka,  Maria Almeida,  Elena Ambrogini,  Li Han,  Paula K. Roberson,  Robert S. Weinstein,  Starros C. Manolagas, 
  • Pages: 851-867
  • First Published: 16 September 2010

Genome-wide screen identifies Escherichia coli TCA-cycle-related mutants with extended chronological lifespan dependent on acetate metabolism and the hypoxia-inducible transcription factor ArcA

Stavros Gonidakis,  Steven E. Finkel,  Valter D. Longo, 
  • Pages: 868-881
  • First Published: 16 September 2010

Modulation of white adipose tissue proteome by aging and calorie restriction

Adamo Valle,  Jordi Sastre-Serra,  Pilar Roca,  Jordi Oliver, 
  • Pages: 882-894
  • First Published: 16 September 2010

Epigenetic changes play critical role in age-associated dysfunctions of the liver

Jingling Jin,  Guo-Li Wang,  Polina Iakova,  Xiurong Shi,  Simon Haefliger,  Milton Finegold,  Nikolai A. Timchenko, 
  • Pages: 895-910
  • First Published: 16 September 2010

Short Take

Tendon-derived stem/progenitor cell aging: defective self-renewal and altered fate

Zuping Zhou,  Takintope Akinbiyi,  Lili Xu,  Melissa Ramcharan,  Daniel J. Leong,  Stephen J. Ros,  Alexis C. Colvin,  Mitchell B. Schaffler,  Robert J. Majeska,  Evan L. Flatow,  Hui B. Sun, 
  • Pages: 911-915
  • First Published: 16 September 2010

Dietary restriction enhances germline stem cell maintenance

William Mair,  Catherine J. McLeod,  Lei Wang,  D. Leanne Jones, 
  • Pages: 916-918
  • First Published: 16 September 2010

The migration of mitochondrial DNA fragments to the nucleus affects the chronological aging process of Saccharomyces cerevisiae

Xin Cheng,  Andreas S. Ivessa, 
  • Pages: 919-923
  • First Published: 16 September 2010

Commentary

Sirt1’s beneficial roles in neurodegenerative diseases – a chaperonin containing TCP-1 (CCT) connection?

Bin Qi Gan,  Bor Luen Tang, 
  • Pages: 924-929
  • First Published: 16 September 2010

Corrigendum

Free Access

Corrigendum

  • Page: 930
  • First Published: 16 September 2010

Announcement

Announcement

  • Page: 931
  • First Published: 16 September 2010