Protein Science: Vol 18, No 5

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Authors Melanie Dietrich, Christina Harprecht and Thilo Stehle on their recently published Protein Science paper entitled "The bulky and the sweet: How neutralizing antibodies and glycan receptors compete for virus binding." Read the paper here

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Protein Science: Volume 18, Issue 5

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Articles

Evaluation at atomic resolution of the role of strain in destabilizing the temperature-sensitive T4 lysozyme mutant Arg 96 → His

Contributions of all 20 amino acids at site 96 to the stability and structure of T4 lysozyme

Structural and functional modularity of proteins in the de novo purine biosynthetic pathway

Structural origin of weakly ordered nitroxide motion in spin-labeled proteins

Contribution of individual histidines to the global stability of human prolactin

Apolipoprotein AI tertiary structures determine stability and phospholipid-binding activity of discoidal high-density lipoprotein particles of different sizes

Practical protocols for production of very high yields of recombinant proteins using Escherichia coli

Building a foundation for structure-based cellulosome design for cellulosic ethanol: Insight into cohesin-dockerin complexation from computer simulation

Nanoscale elongating control of the self-assembled protein filament with the cysteine-introduced building blocks

Correction(s) for this article

Nanoscale elongating control of the self-assembled protein filament with the cysteine-introduced building blocks

Chemical synthesis and biotinylation of the thrombospondin domain TSR2

Trichloroacetic acid-induced protein precipitation involves the reversible association of a stable partially structured intermediate

Sequence requirement and subtype specificity in the high-affinity interaction between human frizzled and dishevelled proteins

Activation of the West Nile virus NS3 protease: Molecular dynamics evidence for a conformational selection mechanism

Engineered disulfides improve mechanical properties of recombinant spider silk

Recombinant chymosin used for exact and complete removal of a prochymosin derived fusion tag releasing intact native target protein

A method for site-specific labeling of multiple protein thiols

Rational redesign of neutral endopeptidase binding to merlin and moesin proteins

Determining protein stability in cell lysates by pulse proteolysis and Western blotting

Thermodynamic characterization of two homologous protein complexes: Associations of the semaphorin receptor plexin-B1 RhoGTPase binding domain with Rnd1 and active Rac1

Crystal structures of the Arabidopsis thaliana proliferating cell nuclear antigen 1 and 2 proteins complexed with the human p21 C-terminal segment

Active site conformational changes of prostasin provide a new mechanism of protease regulation by divalent cations

Key role of the N-terminus of chicken annexin A5 in vesicle aggregation

Protein Structure Report

Structure of a mutant human purine nucleoside phosphorylase with the prodrug, 2-fluoro-2′-deoxyadenosine and the cytotoxic drug, 2-fluoroadenine

For the Records

High-throughput screening of optimal solution conditions for structural biological studies by fluorescence correlation spectroscopy

Selenomethionine incorporation in proteins expressed in Lactococcus lactis

Auxiliary Ca2+ binding sites can influence the structure of CIB1

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Auxiliary Ca²⁺ binding sites can influence the structure of CIB1