Protein Science: Vol 3, No 10

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Authors Melanie Dietrich, Christina Harprecht and Thilo Stehle on their recently published Protein Science paper entitled "The bulky and the sweet: How neutralizing antibodies and glycan receptors compete for virus binding." Read the paper here

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Protein Science: Volume 3, Issue 10

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Invited Tributes

Max Perutz's achievements: How did he do it?

Invited Papers

Polar zippers: Their role in human disease

Control of nucleation of protein crystals

The three-dimensional structures of mutants of porphobilinogen deaminase: Toward an understanding of the structural basis of acute intermittent porphyria

Role and mechanism of the maturation cleavage of VP0 in poliovirus assembly: Structure of the empty capsid assembly intermediate at 2.9 Å resolution

Protein crystallography and infectious diseases

Influenza virus neuraminidase: Structure, antibodies, and inhibitors

Comparison of the intermediate complexes of human growth hormone bound to the human growth hormone and prolactin receptors

Quantification of tertiary structural conservation despite primary sequence drift in the globin fold

Viral cell recognition and entry

Electrostatic effects in the control of glycogen phosphorylase by phosphorylation

Recollections

The beginnings of structural biology

Proteolytic enzymes past and present: The second golden era†

Articles

Sequence determinants of the capping box, a stabilizing motif at the N-termini of α-helices

Probing the catalytic roles of n2-site glutamate residues in Escherichia coli glutamine synthetase by mutagenesis

Structure-function relationship in the globular type III antifreeze protein: Identification of a cluster of surface residues required for binding to ice

Identification of amino acid residues involved in the binding of Huperzine A to cholinesterases

Structural studies of the engrailed homeodomain

Template-assembled melittin: Structural and functional characterization of a designed, synthetic channel-forming protein

Solution structure of the DNA-binding domain of the heat shock transcription factor determined by multidimensional heteronuclear magnetic resonance spectroscopy

Formation of a native-like subdomain in a partially folded intermediate of bovine pancreatic trypsin inhibitor

A common structural motif incorporating a cystine knot and a triple-stranded β-sheet in toxic and inhibitory polypeptides

Three-dimensional model and quaternary structure of the human eye lens protein γS-crystallin based on β- and γ-crystallin X-ray coordinates and ultracentrifugation

Discovering structural correlations in α-helices

Multiple protein structure alignment

A quantitative methodology for the de novo design of proteins

Reviews

Malate dehydrogenase: A model for structure, evolution, and catalysis

For the Records

On the evolution of alternate core packing in eightfold β/α-barrels

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The electronic protein science update

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Proteolytic enzymes past and present: The second golden era ^†

Probing the catalytic roles of n₂-site glutamate residues in Escherichia coli glutamine synthetase by mutagenesis