Journal of Nucleic Acids is an open access journal publishing original research articles as well as review articles covering all structural, chemical, and functional aspects of DNA and RNA research.

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• 1.8Journal Impact Factor
• 29%Acceptance rate
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A Base Pair Outside the Catalytic Core of the I‐R3 DNA Enzyme Has a Significant Effect on Its Cleavage Activity: An Improved Catalytic Core Model and an Automated Design Program

Shahidul Islam, Gabriel Aguiar-Tawil, Xinxin Yu, Jonathan Ouellet, Nawwaf Kharma, 

• First Published:  8 March 2025

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Design and Evaluation of RNA Aptamer–Mediated Delivery of C/EBPβ siRNA for Oncological Therapy

D. Vasconcelos, M. H. Sodergren, V. Reebye, J. Vasara, M. S. Song, K. Holm, S. E. Khorsandi, J. Rossi, N. Habib, K. W. Huang, 

• First Published:  3 March 2025

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Dual Detection of Hepatitis B and C Viruses Using CRISPR‐Cas Systems and Lateral Flow Assay

Syeda Najidah Shahni, Sarah Albogami, Iqbal Azmi, Bijay Pattnaik, Rituparna Chaudhuri, Kapil Dev, Jawed Iqbal, Amit Sharma, Tanveer Ahmad, 

• First Published:  5 October 2024

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Genetic Polymorphisms and Forensic Parameters of Thirteen X‐Chromosome Markers in the Iraqi Kurdish Population

Ara K. Mohammad, Bahez Ismael, Khanzad Ahmed Ali, Balnd M. Albarzinji, 

• First Published:  15 April 2024

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Synthesis and Evaluation of MGB Polyamide‐Oligonucleotide Conjugates as Gene Expression Control Compounds

Kazuo Kamaike, Mutsumi Sano, Daisuke Sakata, Yu Nishihara, Hiroaki Amino, Akihiro Ohtsuki, Yui Okada, Takafumi Miyakawa, Makoto Kogawara, Mai Tsutsumi, Misato Takahashi, Etsuko Kawashima, Koichiro Ota, Hiroaki Miyaoka, 

• First Published:  14 March 2023

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The following is a list of the most cited articles based on citations published in the last three years, according to CrossRef.

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Molecular Mechanisms of Ultraviolet Radiation‐Induced DNA Damage and Repair

Rajesh P. Rastogi,  Richa, Ashok Kumar, Madhu B. Tyagi, Rajeshwar P. Sinha, 

• First Published:  16 December 2010

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H2AX Phosphorylation: Its Role in DNA Damage Response and Cancer Therapy

Monika Podhorecka, Andrzej Skladanowski, Przemyslaw Bozko, 

• First Published:  3 August 2010

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Challenges and Opportunities for Small Molecule Aptamer Development

Maureen McKeague, Maria C. DeRosa, 

• First Published:  24 October 2012

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Cellular Responses to Cisplatin‐Induced DNA Damage

Alakananda Basu, Soumya Krishnamurthy, 

• First Published:  8 August 2010

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DNA Damage Induced by Alkylating Agents and Repair Pathways

Natsuko Kondo, Akihisa Takahashi, Koji Ono, Takeo Ohnishi, 

• First Published:  21 November 2010

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