The Clinical Respiratory Journal

In this study, in vitro experiments on A549 cells and H1299 cells confirmed that oleic acid can inhibit the expression of SDC4, promote the occurrence of ferroptosis in A549 cells and H1299 cells through the GPX4/ACSL4 pathway, and provide an effective basis for the clinical application of targeted ferroptosis drugs in the effective treatment of lung cancer.

Treatment with elexacaftor/tezacaftor/ivacaftor does not lead to changes in depression or anxiety symptoms at the population level. There did not appear to be an effect of the COVID-19 pandemic on these results.

Pyopneumothorax with bronchopleural fistula is a rare complication of lung infection. We herein report a case of pyopneumothorax with bronchopleural fistula caused by Porphyromonas gingivalis infection, a common pathogenic pathogen of periodontitis, in a 49-year-old man with periodontitis. The patient was admitted with respiratory failure. Pleural puncture yielded a lot of gas continually and foul-smelling light brown pus, which was found to be caused due to infection with P. gingivalis by the next generation sequencing (NGS) and anaerobic culture.

Our understanding of the psychological impact of living with pulmonary hypertension (PH) is growing. Evidence exists for the use of psychological interventions in chronic lung conditions; however, trials involving adults with PH have not been subject to a systematic review. We show that although the evidence is limited, the findings are promising and there is a need for more research.

The pleural fluid characteristics associated with COVID-19 infection were assessed in 128 effusions from 106 unique patients; 68.5% of effusions met at least one of the three Light's criteria and therefore were exudative. Elevated LDH was notable. The white blood cell differential was predominantly lymphocytic (in 60.9% of effusions) or neutrophilic (30.5%).

The two EBUS echo features of heterogeneous and absence of a linear-discrete air bronchogram have predictive value for PPLs especially in the presence of two features the pulmonary lesions should be highly suspected malignant tumors.