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ARTICLE
Open Access

oa

Integrative single-cell expression and functional studies unravels a sensitization to cytarabine-based chemotherapy through HIF pathway inhibition in AML leukemia stem cells
Talia Velasco-Hernandez, Juan L. Trincado, Meritxell Vinyoles, Adria Closa, Alba Martínez-Moreno, Francisco Gutiérrez-Agüera, Oscar Molina, Virginia C. Rodríguez-Cortez, Pau Ximeno-Parpal, Narcís Fernández-Fuentes, Paolo Petazzi, Sergi Beneyto-Calabuig, Lars Velten, Paola Romecin, Raquel Casquero, Fernando Abollo-Jiménez, Rafael D. de la Guardia, Patricia Lorden, Alex Bataller, Hélène Lapillonne, Ronald W. Stam, Susana Vives, Montserrat Torrebadell, Jose L. Fuster, Clara Bueno, Jean-Emmanuel Sarry, Eduardo Eyras, Holger Heyn, Pablo Menéndez,

First published: 26 February 2024
LETTER
Open Access

oa

Treatment patterns and outcomes with luspatercept in patients with lower-risk myelodysplastic syndromes: A retrospective US cohort analysis
Sudipto Mukherjee, Cherrishe Brown-Bickerstaff, Angelica Falkenstein, Adeola Y. Makinde, Emily Bland, JaLyna Laney, Marné Garretson, David Huggar, Ali McBride,

First published: 30 January 2024
LETTER
Open Access

oa

Immunodeficient NBSGW mouse strain allows chemotherapy modeling in AML patient-derived xenografts
Vilma Dembitz, Jozef Durko, Joana Campos, Sophie C. James, Hannah Lawson, Kamil R. Kranc, Paolo Gallipoli,

First published: 27 January 2024
Article
Open Access

oa

Thiotepa-busulfan-fludarabine Compared to Treosulfan-based Conditioning for Haploidentical Transplant With Posttransplant Cyclophosphamide in Patients With Acute Myeloid Leukemia in Remission: A Study From the Acute Leukemia Working Party of the EBMT
Francesco Saraceni, Myriam Labopin, Anna M. Raiola, Didier Blaise, Péter Reményi, Federica Sorà, Jiri Pavlu, Stefania Bramanti, Alessandro Busca, Ana Berceanu, Giorgia Battipaglia, Giuseppe Visani, Gerard Sociè, Gesine Bug, Caterina Micò, Giorgio La Nasa, Maurizio Musso, Attilio Olivieri, Alexandros Spyridonidis, Bipin Savani, Fabio Ciceri, Arnon Nagler, Mohamad Mohty, Acute Leukemia Working Party (ALWP) of the European Society for Blood and Marrow Transplantation (EBMT),

First published: 01 October 2023

Graphical Abstract
Article
Open Access

oa

CSF3R T618I Collaborates With RUNX1-RUNX1T1 to Expand Hematopoietic Progenitors and Sensitizes to GLI Inhibition
Anja S. Swoboda, Vanessa C. Arfelli, Anna Danese, Roland Windisch, Paul Kerbs, Enric Redondo Monte, Johannes W. Bagnoli, Linping Chen-Wichmann, Alessandra Caroleo, Monica Cusan, Stefan Krebs, Helmut Blum, Michael Sterr, Wolfgang Enard, Tobias Herold, Maria Colomé-Tatché, Christian Wichmann, Philipp A. Greif,

First published: 01 October 2023

Graphical Abstract
Review Article
Open Access

oa

EVI1-mediated Programming of Normal and Malignant Hematopoiesis
Susanne Lux, Michael D. Milsom,

First published: 01 October 2023

Collections: Reviews
Article
Open Access

oa

Machine Learning Improves Risk Stratification in Myelodysplastic Neoplasms: An Analysis of the Spanish Group of Myelodysplastic Syndromes
Adrian Mosquera Orgueira, Manuel Mateo Perez Encinas, Nicolas A Diaz Varela, Elvira Mora, Marina Díaz-Beyá, María Julia Montoro, Helena Pomares, Fernando Ramos, Mar Tormo, Andres Jerez, Josep F Nomdedeu, Carlos De Miguel Sanchez, Arenillas Leonor, Paula Cárcel, Maria Teresa Cedena Romero, Blanca Xicoy, Eugenia Rivero, Rafael Andres del Orbe Barreto, Maria Diez-Campelo, Luis E. Benlloch, Davide Crucitti, David Valcárcel,

First published: 01 October 2023

Graphical Abstract
Article
Open Access

oa

Momelotinib in Myelofibrosis Patients With Thrombocytopenia: Post Hoc Analysis From Three Randomized Phase 3 Trials
Jean-Jacques Kiladjian, Alessandro M. Vannucchi, Aaron T. Gerds, Vikas Gupta, Srdan Verstovsek, Miklos Egyed, Uwe Platzbecker, Jiří Mayer, Sebastian Grosicki, Árpád Illés, Tomasz Woźny, Stephen T. Oh, Donal McLornan, Ilya Kirgner, Sung-Soo Yoon, Claire N. Harrison, Barbara Klencke, Mei Huang, Jun Kawashima, Ruben Mesa,

First published: 01 October 2023

Graphical Abstract
Article
Open Access

oa

Patient-reported Outcomes and Quality of Life in Anemic and Symptomatic Patients With Myelofibrosis: Results From the MOMENTUM Study
Ruben A. Mesa, Claire Harrison, Jeanne M. Palmer, Vikas Gupta, Donal P. McLornan, Mary Frances McMullin, Jean-Jacques Kiladjian, Lynda Foltz, Uwe Platzbecker, Maria Laura Fox, Adam J. Mead, David M. Ross, Stephen T. Oh, Andrew Charles Perkins, Michael F. Leahy, Jun Kawashima, Sunhee Ro, Rafe Donahue, Boris Gorsh, Samineh Deheshi, Srdan Verstovsek,

First published: 01 October 2023

Graphical Abstract
Letter
Open Access

oa

Durable Responses and Survival in High-risk Myelodysplastic Syndrome and Acute Myeloid Leukemia Patients Receiving the Allogeneic Leukemia-derived Dendritic Cell Vaccine DCP-001
Luca L.G. Janssen, Theresia M. Westers, Jeroen Rovers, Peter J.M. Valk, Jacqueline Cloos, Tanja D. de Gruijl, Arjan A. van de Loosdrecht,

First published: 01 October 2023
Article
Open Access

oa

Integration of Transcriptomic Features to Improve Prognosis Prediction of Pediatric Acute Myeloid Leukemia With KMT2A Rearrangement
Jun Li, Suyu Zong, Yang Wan, Min Ruan, Li Zhang, Wenyu Yang, Xiaojuan Chen, Yao Zou, Yumei Chen, Ye Guo, Peng Wu, Yingchi Zhang, Xiaofan Zhu,

First published: 01 October 2023

Collections: Pediatric Hematology

Graphical Abstract
Letter
Open Access

oa

Prognostic Significance of Measurable Residual Disease Detection by Flow Cytometry in Autologous Stem Cell Apheresis Products in AML
Jesse M. Tettero, Yara Buisman, Lok Lam Ngai, Costa Bachas, Bjorn T. Gjertsen, Angèle Kelder, Arjan A. van de Loosdrecht, Markus G. Manz, Thomas Pabst, Willemijn Scholten, Gert J. Ossenkoppele, Jacqueline Cloos, David C. de Leeuw,

First published: 01 October 2023
Article
Open Access

oa

Health-related Quality of Life Profile of Newly Diagnosed Patients With Myelodysplastic Syndromes by Age, Sex, and Risk Group: A Real-world Study by the GIMEMA
Fabio Efficace, Wael Al Essa, Uwe Platzbecker, Pasquale Niscola, Giuseppe A. Palumbo, Giovanni Caocci, Francesco Cottone, Massimo Breccia, Mario Luppi, Reinhard Stauder, Alessandra Ricco, Duska Petranovic, Frederic Baron, Maria Teresa Voso, Luana Fianchi, Chiara Frairia, Isabella Capodanno, Chiara Sarlo, Marilena Fedele, Roberto Massimo Lemoli, Rosangela Invernizzi, Daniele Vallisa, Nicola Di Renzo, Claudio Fozza, Maribel Doro, Johannes M. Giesinger, Marco Vignetti,

First published: 30 August 2023

Graphical Abstract
Article
Open Access

oa

Targeted High-throughput Sequencing for Hematological Malignancies: A GBMHM Survey of Practice and Cost Evaluation in France
Meryl Darlington, Pierre Sujobert, Olivier Kosmider, Damien Luque Paz, Sophie Kaltenbach, Martin Figeac, Sandrine Hayette, Nadia Mezaour, Séverine Coquerelle, Anne-Sophie Alary, Audrey Bidet, Yannick Le Bris, Eric Delabesse, Frédéric Davi, Claude Preudhomme, Isabelle Durand-Zaleski, Elizabeth Macintyre, Groupe des Biologistes Moléculaires des Hémopathies Malignes (GBMHM)*, Mélissa Alame, Fanny Baran-Marzak, Marc G. Berger, Dominique Bories, Aurélie Caye-Eude, Jean-Michel Cayuela, Pascale Cornillet-Lefebvre, François Delhommeau, Marie-Hélène Estienne-Felix, Pascaline Etancelin, Pascale Flandrin-Gresta, Eric Lippert, Christophe Marzac, Laurent Miguet, Cédric Pastoret, Sophie Raynaud, David Rizzo,

First published: 24 August 2023

Graphical Abstract
Review Article
Open Access

oa

CAR-T in the Treatment of Acute Myeloid Leukemia: Barriers and How to Overcome Them
Jolien Vanhooren, Rani Dobbelaere, Charlotte Derpoorter, Larissa Deneweth, Laurens Van Camp, Anne Uyttebroeck, Barbara De Moerloose, Tim Lammens,

First published: 18 August 2023

Collections: Reviews
Perspective
Open Access

oa

Genetic Predisposition to Clonal Hematopoiesis
Pedro M. Quiros, George S. Vassiliou,

First published: 17 August 2023
Article
Open Access

oa

The MLL–Menin Interaction is a Therapeutic Vulnerability in NUP98-rearranged AML
Milad Rasouli, Helen Blair, Selina Troester, Katarzyna Szoltysek, Rachel Cameron, Minoo Ashtiani, Anja Krippner-Heidenreich, Florian Grebien, Gerard McGeehan, C. Michel Zwaan, Olaf Heidenreich,

First published: 27 July 2023

Graphical Abstract
Article
Open Access

oa

Application of IPSET-thrombosis in 1366 Patients Prospectively Followed From the Spanish Registry of Essential Thrombocythemia
Alberto Alvarez-Larrán, Beatriz Cuevas, Patricia Velez, Soledad Noya, Gonzalo Caballero-Navarro, Francisca Ferrer-Marín, Sara Carbonell, Manuel Pérez-Encinas, María Teresa Gómez-Casares, Raúl Pérez-López, Elena Magro, Ana Moretó, Irene Pastor-Galán, Anna Angona, María Isabel Mata-Vázquez, Lucía Guerrero-Fernández, José María Guerra, Gonzalo Carreño-Tarragona, Laura Fox, Ilda Murillo, Valentín García-Gutiérrez, Elvira Mora, Ruth Stuckey, Eduardo Arellano-Rodrigo, Juan Carlos Hernández-Boluda, Arturo Pereira, MPN Spanish Group (GEMFIN),

First published: 18 July 2023
Review Article
Open Access

oa

Histone Variants and Their Chaperones in Hematological Malignancies
Ecem Kirkiz, Oliver Meers, Florian Grebien, Marcus Buschbeck,

First published: 11 July 2023

Collections: Reviews
Article
Open Access

oa

Significance of Degree of HLA Disparity Using T-cell Replete Peripheral Blood Stem Cells From Haploidentical Donors With Posttransplantation Cyclophosphamide in AML in First Complete Hematologic Remission: A Study of the Acute Leukemia Working Party of the EBMT
Mohamed A. Kharfan-Dabaja, Myriam Labopin, Ernesto Ayala, Ali Bazarbachi, Didier Blaise, Jan Vydra, Stefania Bramanti, Maija Itälä-Remes, Christoph Schmid, Alessandro Busca, Edouard Forcade, Werner Rabitsch, Marco Zecca, Nicolaus Kröger, Claude-Eric Bulabois, Giovanni Grillo, Alessandro Rambaldi, Renato Fanin, Francesco Zallio, Nicola Di Renzo, Yener Koc, Yana Novis, Andrew McDonald, Concepcion Herrera Arroyo, Jaime Sanz, Arnon Nagler, Fabio Ciceri, Mohamad Mohty,

First published: 27 June 2023

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oa

Integrative single-cell expression and functional studies unravels a sensitization to cytarabine-based chemotherapy through HIF pathway inhibition in AML leukemia stem cells

oa

Treatment patterns and outcomes with luspatercept in patients with lower-risk myelodysplastic syndromes: A retrospective US cohort analysis

oa

Immunodeficient NBSGW mouse strain allows chemotherapy modeling in AML patient-derived xenografts

oa

Thiotepa-busulfan-fludarabine Compared to Treosulfan-based Conditioning for Haploidentical Transplant With Posttransplant Cyclophosphamide in Patients With Acute Myeloid Leukemia in Remission: A Study From the Acute Leukemia Working Party of the EBMT

Graphical Abstract

oa

CSF3R T618I Collaborates With RUNX1-RUNX1T1 to Expand Hematopoietic Progenitors and Sensitizes to GLI Inhibition

Graphical Abstract

oa

EVI1-mediated Programming of Normal and Malignant Hematopoiesis

oa

Machine Learning Improves Risk Stratification in Myelodysplastic Neoplasms: An Analysis of the Spanish Group of Myelodysplastic Syndromes

Graphical Abstract

oa

Momelotinib in Myelofibrosis Patients With Thrombocytopenia: Post Hoc Analysis From Three Randomized Phase 3 Trials

Graphical Abstract

oa

Patient-reported Outcomes and Quality of Life in Anemic and Symptomatic Patients With Myelofibrosis: Results From the MOMENTUM Study

Graphical Abstract

oa

Durable Responses and Survival in High-risk Myelodysplastic Syndrome and Acute Myeloid Leukemia Patients Receiving the Allogeneic Leukemia-derived Dendritic Cell Vaccine DCP-001

oa

Integration of Transcriptomic Features to Improve Prognosis Prediction of Pediatric Acute Myeloid Leukemia With KMT2A Rearrangement

Graphical Abstract

oa

Prognostic Significance of Measurable Residual Disease Detection by Flow Cytometry in Autologous Stem Cell Apheresis Products in AML

oa

Health-related Quality of Life Profile of Newly Diagnosed Patients With Myelodysplastic Syndromes by Age, Sex, and Risk Group: A Real-world Study by the GIMEMA

Graphical Abstract

oa

Targeted High-throughput Sequencing for Hematological Malignancies: A GBMHM Survey of Practice and Cost Evaluation in France

Graphical Abstract

oa

CAR-T in the Treatment of Acute Myeloid Leukemia: Barriers and How to Overcome Them

oa

Genetic Predisposition to Clonal Hematopoiesis

oa

The MLL–Menin Interaction is a Therapeutic Vulnerability in NUP98-rearranged AML

Graphical Abstract

oa

Application of IPSET-thrombosis in 1366 Patients Prospectively Followed From the Spanish Registry of Essential Thrombocythemia

oa

Histone Variants and Their Chaperones in Hematological Malignancies

oa

Significance of Degree of HLA Disparity Using T-cell Replete Peripheral Blood Stem Cells From Haploidentical Donors With Posttransplantation Cyclophosphamide in AML in First Complete Hematologic Remission: A Study of the Acute Leukemia Working Party of the EBMT

Graphical Abstract

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oa Integrative single-cell expression and functional studies unravels a sensitization to cytarabine-based chemotherapy through HIF pathway inhibition in AML leukemia stem cells

oa Treatment patterns and outcomes with luspatercept in patients with lower-risk myelodysplastic syndromes: A retrospective US cohort analysis

oa Immunodeficient NBSGW mouse strain allows chemotherapy modeling in AML patient-derived xenografts

oa Thiotepa-busulfan-fludarabine Compared to Treosulfan-based Conditioning for Haploidentical Transplant With Posttransplant Cyclophosphamide in Patients With Acute Myeloid Leukemia in Remission: A Study From the Acute Leukemia Working Party of the EBMT

Graphical Abstract

oa CSF3R T618I Collaborates With RUNX1-RUNX1T1 to Expand Hematopoietic Progenitors and Sensitizes to GLI Inhibition

Graphical Abstract

oa EVI1-mediated Programming of Normal and Malignant Hematopoiesis

oa Machine Learning Improves Risk Stratification in Myelodysplastic Neoplasms: An Analysis of the Spanish Group of Myelodysplastic Syndromes

Graphical Abstract

oa Momelotinib in Myelofibrosis Patients With Thrombocytopenia: Post Hoc Analysis From Three Randomized Phase 3 Trials

Graphical Abstract

oa Patient-reported Outcomes and Quality of Life in Anemic and Symptomatic Patients With Myelofibrosis: Results From the MOMENTUM Study

Graphical Abstract

oa Durable Responses and Survival in High-risk Myelodysplastic Syndrome and Acute Myeloid Leukemia Patients Receiving the Allogeneic Leukemia-derived Dendritic Cell Vaccine DCP-001

oa Integration of Transcriptomic Features to Improve Prognosis Prediction of Pediatric Acute Myeloid Leukemia With KMT2A Rearrangement

Graphical Abstract

oa Prognostic Significance of Measurable Residual Disease Detection by Flow Cytometry in Autologous Stem Cell Apheresis Products in AML

oa Health-related Quality of Life Profile of Newly Diagnosed Patients With Myelodysplastic Syndromes by Age, Sex, and Risk Group: A Real-world Study by the GIMEMA

Graphical Abstract

oa Targeted High-throughput Sequencing for Hematological Malignancies: A GBMHM Survey of Practice and Cost Evaluation in France

Graphical Abstract

oa CAR-T in the Treatment of Acute Myeloid Leukemia: Barriers and How to Overcome Them

oa Genetic Predisposition to Clonal Hematopoiesis

oa The MLL–Menin Interaction is a Therapeutic Vulnerability in NUP98-rearranged AML

Graphical Abstract

oa Application of IPSET-thrombosis in 1366 Patients Prospectively Followed From the Spanish Registry of Essential Thrombocythemia

oa Histone Variants and Their Chaperones in Hematological Malignancies

oa Significance of Degree of HLA Disparity Using T-cell Replete Peripheral Blood Stem Cells From Haploidentical Donors With Posttransplantation Cyclophosphamide in AML in First Complete Hematologic Remission: A Study of the Acute Leukemia Working Party of the EBMT

Graphical Abstract

oa

Integrative single-cell expression and functional studies unravels a sensitization to cytarabine-based chemotherapy through HIF pathway inhibition in AML leukemia stem cells

oa

Treatment patterns and outcomes with luspatercept in patients with lower-risk myelodysplastic syndromes: A retrospective US cohort analysis

oa

Immunodeficient NBSGW mouse strain allows chemotherapy modeling in AML patient-derived xenografts

oa

Thiotepa-busulfan-fludarabine Compared to Treosulfan-based Conditioning for Haploidentical Transplant With Posttransplant Cyclophosphamide in Patients With Acute Myeloid Leukemia in Remission: A Study From the Acute Leukemia Working Party of the EBMT

oa

CSF3R T618I Collaborates With RUNX1-RUNX1T1 to Expand Hematopoietic Progenitors and Sensitizes to GLI Inhibition

oa

EVI1-mediated Programming of Normal and Malignant Hematopoiesis

oa

Machine Learning Improves Risk Stratification in Myelodysplastic Neoplasms: An Analysis of the Spanish Group of Myelodysplastic Syndromes

oa

Momelotinib in Myelofibrosis Patients With Thrombocytopenia: Post Hoc Analysis From Three Randomized Phase 3 Trials

oa

Patient-reported Outcomes and Quality of Life in Anemic and Symptomatic Patients With Myelofibrosis: Results From the MOMENTUM Study

oa

Durable Responses and Survival in High-risk Myelodysplastic Syndrome and Acute Myeloid Leukemia Patients Receiving the Allogeneic Leukemia-derived Dendritic Cell Vaccine DCP-001

oa

Integration of Transcriptomic Features to Improve Prognosis Prediction of Pediatric Acute Myeloid Leukemia With KMT2A Rearrangement

oa

Prognostic Significance of Measurable Residual Disease Detection by Flow Cytometry in Autologous Stem Cell Apheresis Products in AML

oa

Health-related Quality of Life Profile of Newly Diagnosed Patients With Myelodysplastic Syndromes by Age, Sex, and Risk Group: A Real-world Study by the GIMEMA

oa

Targeted High-throughput Sequencing for Hematological Malignancies: A GBMHM Survey of Practice and Cost Evaluation in France

oa

CAR-T in the Treatment of Acute Myeloid Leukemia: Barriers and How to Overcome Them

oa

Genetic Predisposition to Clonal Hematopoiesis

oa

The MLL–Menin Interaction is a Therapeutic Vulnerability in NUP98-rearranged AML

oa

Application of IPSET-thrombosis in 1366 Patients Prospectively Followed From the Spanish Registry of Essential Thrombocythemia

oa

Histone Variants and Their Chaperones in Hematological Malignancies

oa

Significance of Degree of HLA Disparity Using T-cell Replete Peripheral Blood Stem Cells From Haploidentical Donors With Posttransplantation Cyclophosphamide in AML in First Complete Hematologic Remission: A Study of the Acute Leukemia Working Party of the EBMT