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LETTER
Open Access

oa

Clonal hematopoiesis of indeterminate potential (CHIP) and risk of non-Hodgkin lymphoma: A community-based cohort study
Mingcheng Liu, Luyao Zhou, Qiaoxue Liu, Xiaojing Wang, Hui Wei, Qianwei Liu,

First published: 27 July 2025
ARTICLE
Open Access

oa

PRC2-mediated apoptosis evasion is a therapeutic target of MDS/AML harboring inv(3)/t(3;3) and monosomy 7
Hiroyoshi Kunimoto, Ayaka Miura, Maiko Sagisaka, Mieko Ito, Ryoichi Maenosono, Hirofumi Yamauchi, Kazuki Nishimura, Daisuke Honma, Shinji Tsutsumi, Akiko Adachi, Takayuki Sakuma, Takuma Ohashi, Hiroshi Teranaka, Junji Ikeda, Sei Samukawa, Takashi Toya, Yuka Harada, Noriko Doki, Sheng F. Cai, Hiroaki Maki, Hiroaki Goto, Akihide Yoshimi, Hideaki Nakajima,

First published: 13 July 2025

Graphical Abstract
ARTICLE
Open Access

oa

Surface downmodulation of TIM3 safeguards healthy cells but not acute myeloid leukemia from CAR T-cell therapy
Jort J. van der Schans, Paresh Vishwasrao, Renée Poels, Morgan Antti, Ziyu Wang, Marjolein Quik, Jennemiek van Arkel, Tom Reuvekamp, Niels W. C. J. van de Donk, Maria Themeli, Gert J. Ossenkoppele, Arjan A. van de Loosdrecht, Rebecca Richards, Tuna Mutis,

First published: 13 July 2025
ARTICLE
Open Access

oa

Expanding the phenotypic and genetic landscape of congenital neutropenia through whole-exome and genome sequencing
Séverine Marti, Philippe Pellet, Blandine Beaupain, Léa Durix, Julien Buratti, Yves Réguerre, Nathalie Aladjidi, Saba Azarnoush, Severine Clauin, Wahid Abou Chahla, Gilles Blaison, Jeremy Bertand, Damien Bodet, Benoit Brethon, Jessica Chane-Teng, Manon Delafoy, Chrystelle Dupraz, Virginie Gandemer, Philippe Denizeau, Alice Goldenberg, Pierre Hirsch, Anaïs l'Haridon, Aude Marie-Cardine, Gabriella Vera, Brigitte Nelken, Laure Nizery, Marie Nolla, Marlène Pasquet, Jérémie Rosain, Louis Terriou, Isabelle Plo, Jean Donadieu, Christine Bellanné-Chantelot,

First published: 11 June 2025

Graphical Abstract
ARTICLE
Open Access

oa

Genetic evolution and relapse-associated mutations in adult T-cell acute lymphoblastic leukemia patients treated in PETHEMA trials
Celia González-Gil, Thaysa Lopes, Mireia Morgades, Francisco Fuster-Tormo, Pau Montesinos, Carlos Rodríguez Medina, Lourdes Hermosín, Teresa González-Martínez, María-Paz Queipo, José González-Campos, Pilar Martínez-Sánchez, Marina Díaz-Beya, Rosa Coll, Clara Maluquer, Lurdes Zamora, Teresa Artola, Ferran Vall-Llovera, Mar Tormo, Anna Torrent, Carolina Martínez-Laperche, Cristina Gil-Cortés, Pere Barba, Marta Cervera, Jordi Ribera, Manuel Fernández-Delgado, Rosa Ayala, Antonia Cladera, María Carmen Mateos, María Jesús Vidal, Jesús Feliu, Ana Torres, Gemma Azaceta, María José Calasanz, Anna Bigas, Manel Esteller, Alberto Orfao, Josep Maria Ribera, Eulalia Genescà,

First published: 26 May 2025

Graphical Abstract
REVIEW ARTICLE
Open Access

oa

Applications of machine learning for immunophenotypic measurable residual disease assessment in acute myeloid leukemia
Tim R. Mocking, Arjan A. van de Loosdrecht, Jacqueline Cloos, Costa Bachas,

First published: 21 May 2025

Collections: Reviews
REVIEW ARTICLE
Open Access

oa

Metabolism in hematology: Technological advances open new perspectives on disease biology and treatment
Eileen Haring, Joerg M. Buescher, Petya Apostolova,

First published: 19 May 2025

Collections: Reviews
LETTER
Open Access

oa

Event-free survival in early polycythemia vera patients correlates with molecular response to ropeginterferon alfa-2b or hydroxyurea/best available therapy (PROUD-PV/CONTINUATION-PV)
Jean-Jacques Kiladjian, Christoph Klade, Pencho Georgiev, Dorota Krochmalczyk, Liana Gercheva-Kyuchukova, Miklos Egyed, Petr Dulicek, Arpad Illes, Halyna Pylypenko, Lylia Sivcheva, Jiří Mayer, Vera Yablokova, Kurt Krejcy, Victoria Empson, Hans C. Hasselbalch, Robert Kralovics, Heinz Gisslinger, for the PROUD-PV Study Group,

First published: 03 May 2025
ARTICLE
Open Access

oa

Orchestration of human multi-lineage hematopoietic cell development by humanized in vivo bone marrow models
Laurent Renou, Wenjie Sun, Chloe Friedrich, Klaudia Galant, Cecile Conrad, Anne Consalus, Evelia Plantier, Katharina Schallmoser, Linda Krisch, Vilma Barroca, Saryami Devanand, Nathalie Dechamps, Andreas Reinisch, Jelena Martinovic, Alessandra Magnani, Lionel Faivre, Daniel Lewandowski, Julien Calvo, Leila Perie, Olivier Kosmider, Françoise Pflumio,

First published: 22 April 2025

Graphical Abstract
LETTER
Open Access

oa

Spironolactone inhibits the NLRP1 inflammasome and alleviates defective erythropoiesis in Diamond-Blackfan anemia
Lola Rodríguez-Ruiz, Juan M. Lozano-Gil, María Ocaña-Esparza, Ana M. Conesa-Hernández, Ana B. Pérez-Oliva, José L. Fuster, Andrés Jérez, Laura Murillo-Sanjuán, Cristina Díaz-de-Heredia, Guzmán López-de-Hontanar, Julián Sevilla, Diana García-Moreno, María L. Cayuela, Alicia Martínez-López, Sylwia D. Tyrkalska, Victoriano Mulero,

First published: 17 April 2025
PERSPECTIVE
Open Access

oa

Implementation science in hemato-oncology molecular diagnostics in France via the Groupe des Biologistes Moléculaire des Hémopathies Malignes (GBMHM)
Jean-Michel Cayuela, Pierre Sujobert, Pascale Flandrin-Gresta, Anne-Sophie Alary, Carole Maute, Damien Luque-Paz, Cédric Pastoret, Stéphanie Dulucq, Audrey Gauthier, Meryl Darlington, Isabelle Durand-Zaleski, Olivier Kosmider, Elizabeth Macintyre,

First published: 08 April 2025
ARTICLE
Open Access

oa

NGS-MRD negativity in post-HSCT ALL spares unnecessary therapeutic interventions triggered by borderline qPCR results without an increase in relapse risk
Krystof Seferna, Michael Svaton, Andrea Rennerova, Aneta Skotnicova, Leona Reznickova, Tatana Valova, Petr Sedlacek, Petr Riha, Renata Formankova, Petra Keslova, Lucie Sramkova, Jan Stary, Jan Zuna, Alexandra Kolenova, Cyril Salek, Jan Trka, Eva Fronkova,

First published: 08 April 2025
ARTICLE
Open Access

oa

H1-0 is a specific mediator of the repressive ETV6::RUNX1 transcriptional landscape in preleukemia and B cell acute lymphoblastic leukemia
Vera H. Jepsen, Andrea Hanel, Daniel Picard, Rigveda Bhave, Rebecca Hasselmann, Juha Mehtonen, Julian Schliehe-Diecks, Carla-Johanna Kath, Vithusan Suppiyar, Yash Prasad, Katerina Schaal, Jia-Wey Tu, Nadine Rüchel, Ersen Kameri, Nan Qin, Herui Wang, Zhengping Zhuang, Rabea Wagener, Lena Blümel, Tobias Lautwein, Daniel Hein, David Koppstein, Gesine Kögler, Marc Remke, Sanil Bhatia, Merja Heinäniemi, Arndt Borkhardt, Ute Fischer,

First published: 02 April 2025

Graphical Abstract
ARTICLE
Open Access

oa

Patient and physician perceptions regarding treatment expectations and symptomatology in polycythemia vera: Insights from the Landmark 2.0 global health survey
Claire N. Harrison, David M. Ross, Laura Maria Fogliatto, Lynda Foltz, Lambert Busque, Zhijian Xiao, Florian H. Heidel, Michael Koehler, Giuseppe A. Palumbo, Massimo Breccia, Norio Komatsu, Keita Kirito, Blanca Xicoy Cirici, Joaquin Martinez-Lopez, Alicia Rovo, Cheryl Petruk, Catalin Bobirca, Laura Mirams, Abigail McMillan, Gavin Harper, Jean-Jacques Kiladjian,

First published: 24 March 2025
HemaTopics
Open Access

oa

Mastering fate: Redistributing a pioneer protein to rewrite leukemia's script
Yizhou Huang, Charles E. de Bock,

First published: 22 January 2025

Collections: HemaTopics
REVIEW ARTICLE
Open Access

oa

Models for the marrow: A comprehensive review of AI-based cell classification methods and malignancy detection in bone marrow aspirate smears
Tabita Ghete, Farina Kock, Martina Pontones, David Pfrang, Max Westphal, Henning Höfener, Markus Metzler,

First published: 03 December 2024

Collections: Reviews
ARTICLE
Open Access

oa

Sevuparin strongly reduces hepcidin expression in cells, mice, and healthy human volunteers
Michela Asperti, Andrea Denardo, Magdalena Gryzik, Kristina E. M. Persson, Göran Westerberg, John Öhd, Maura Poli,

First published: 28 November 2024

Graphical Abstract
HemaTopics
Open Access

oa

IL-11—An aging-related cytokine with opportunities for regulating hematopoiesis
David G. Kent,

First published: 19 November 2024

Collections: HemaTopics
ARTICLE
Open Access

oa

Antibiotic-associated neutropenia is marked by the depletion of intestinal Lachnospiraceae and associated metabolites in pediatric patients
Josaura Fernandez-Sanchez, Rachel Rodgers, Arushana A. Maknojia, Nusrat Shaikh, Hannah Yan, Marlyd E. Mejia, Hope Hendricks, Robert R. Jenq, Pavan Reddy, Ritu Banerjee, Jeremy M. Schraw, Megan T. Baldridge, Katherine Y. King,

First published: 07 November 2024

Collections: Pediatric Hematology

Graphical Abstract
LETTER
Open Access

oa

How to diagnose acid sphingomyelinase deficiency (ASMD) and Niemann–Pick disease type C from bone marrow and peripheral blood smears
Sandrine Girard, Magali Pettazzoni, Roseline Froissart, Cécile Pagan, Thomas Boyer, Stephanie Dulucq, Valérie Gonçalves Monteiro, Nicolas Lechevalier, Marie Loosveld, Camille Lours, Caroline Mayeur-Rousse, Mélanie Pannetier, Caroline Peillon, Maria-Alessandra Rosenthal, Sonnthida Sep Hieng, Catherine Trichet, Lucile Baseggio, on behalf the French-Speaking Cellular Haematology Group (GFHC),

First published: 05 November 2024

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oa

Clonal hematopoiesis of indeterminate potential (CHIP) and risk of non-Hodgkin lymphoma: A community-based cohort study

oa

PRC2-mediated apoptosis evasion is a therapeutic target of MDS/AML harboring inv(3)/t(3;3) and monosomy 7

Graphical Abstract

oa

Surface downmodulation of TIM3 safeguards healthy cells but not acute myeloid leukemia from CAR T-cell therapy

oa

Expanding the phenotypic and genetic landscape of congenital neutropenia through whole-exome and genome sequencing

Graphical Abstract

oa

Genetic evolution and relapse-associated mutations in adult T-cell acute lymphoblastic leukemia patients treated in PETHEMA trials

Graphical Abstract

oa

Applications of machine learning for immunophenotypic measurable residual disease assessment in acute myeloid leukemia

oa

Metabolism in hematology: Technological advances open new perspectives on disease biology and treatment

oa

Event-free survival in early polycythemia vera patients correlates with molecular response to ropeginterferon alfa-2b or hydroxyurea/best available therapy (PROUD-PV/CONTINUATION-PV)

oa

Orchestration of human multi-lineage hematopoietic cell development by humanized in vivo bone marrow models

Graphical Abstract

oa

Spironolactone inhibits the NLRP1 inflammasome and alleviates defective erythropoiesis in Diamond-Blackfan anemia

oa

Implementation science in hemato-oncology molecular diagnostics in France via the Groupe des Biologistes Moléculaire des Hémopathies Malignes (GBMHM)

oa

NGS-MRD negativity in post-HSCT ALL spares unnecessary therapeutic interventions triggered by borderline qPCR results without an increase in relapse risk

oa

H1-0 is a specific mediator of the repressive ETV6::RUNX1 transcriptional landscape in preleukemia and B cell acute lymphoblastic leukemia

Graphical Abstract

oa

Patient and physician perceptions regarding treatment expectations and symptomatology in polycythemia vera: Insights from the Landmark 2.0 global health survey

oa

Mastering fate: Redistributing a pioneer protein to rewrite leukemia's script

oa

Models for the marrow: A comprehensive review of AI-based cell classification methods and malignancy detection in bone marrow aspirate smears

oa

Sevuparin strongly reduces hepcidin expression in cells, mice, and healthy human volunteers

Graphical Abstract

oa

IL-11—An aging-related cytokine with opportunities for regulating hematopoiesis

oa

Antibiotic-associated neutropenia is marked by the depletion of intestinal Lachnospiraceae and associated metabolites in pediatric patients

Graphical Abstract

oa

How to diagnose acid sphingomyelinase deficiency (ASMD) and Niemann–Pick disease type C from bone marrow and peripheral blood smears

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oa Clonal hematopoiesis of indeterminate potential (CHIP) and risk of non-Hodgkin lymphoma: A community-based cohort study

oa PRC2-mediated apoptosis evasion is a therapeutic target of MDS/AML harboring inv(3)/t(3;3) and monosomy 7

Graphical Abstract

oa Surface downmodulation of TIM3 safeguards healthy cells but not acute myeloid leukemia from CAR T-cell therapy

oa Expanding the phenotypic and genetic landscape of congenital neutropenia through whole-exome and genome sequencing

Graphical Abstract

oa Genetic evolution and relapse-associated mutations in adult T-cell acute lymphoblastic leukemia patients treated in PETHEMA trials

Graphical Abstract

oa Applications of machine learning for immunophenotypic measurable residual disease assessment in acute myeloid leukemia

oa Metabolism in hematology: Technological advances open new perspectives on disease biology and treatment

oa Event-free survival in early polycythemia vera patients correlates with molecular response to ropeginterferon alfa-2b or hydroxyurea/best available therapy (PROUD-PV/CONTINUATION-PV)

oa Orchestration of human multi-lineage hematopoietic cell development by humanized in vivo bone marrow models

Graphical Abstract

oa Spironolactone inhibits the NLRP1 inflammasome and alleviates defective erythropoiesis in Diamond-Blackfan anemia

oa Implementation science in hemato-oncology molecular diagnostics in France via the Groupe des Biologistes Moléculaire des Hémopathies Malignes (GBMHM)

oa NGS-MRD negativity in post-HSCT ALL spares unnecessary therapeutic interventions triggered by borderline qPCR results without an increase in relapse risk

oa H1-0 is a specific mediator of the repressive ETV6::RUNX1 transcriptional landscape in preleukemia and B cell acute lymphoblastic leukemia

Graphical Abstract

oa Patient and physician perceptions regarding treatment expectations and symptomatology in polycythemia vera: Insights from the Landmark 2.0 global health survey

oa Mastering fate: Redistributing a pioneer protein to rewrite leukemia's script

oa Models for the marrow: A comprehensive review of AI-based cell classification methods and malignancy detection in bone marrow aspirate smears

oa Sevuparin strongly reduces hepcidin expression in cells, mice, and healthy human volunteers

Graphical Abstract

oa IL-11—An aging-related cytokine with opportunities for regulating hematopoiesis

oa Antibiotic-associated neutropenia is marked by the depletion of intestinal Lachnospiraceae and associated metabolites in pediatric patients

Graphical Abstract

oa How to diagnose acid sphingomyelinase deficiency (ASMD) and Niemann–Pick disease type C from bone marrow and peripheral blood smears

oa

Clonal hematopoiesis of indeterminate potential (CHIP) and risk of non-Hodgkin lymphoma: A community-based cohort study

oa

PRC2-mediated apoptosis evasion is a therapeutic target of MDS/AML harboring inv(3)/t(3;3) and monosomy 7

oa

Surface downmodulation of TIM3 safeguards healthy cells but not acute myeloid leukemia from CAR T-cell therapy

oa

Expanding the phenotypic and genetic landscape of congenital neutropenia through whole-exome and genome sequencing

oa

Genetic evolution and relapse-associated mutations in adult T-cell acute lymphoblastic leukemia patients treated in PETHEMA trials

oa

Applications of machine learning for immunophenotypic measurable residual disease assessment in acute myeloid leukemia

oa

Metabolism in hematology: Technological advances open new perspectives on disease biology and treatment

oa

Event-free survival in early polycythemia vera patients correlates with molecular response to ropeginterferon alfa-2b or hydroxyurea/best available therapy (PROUD-PV/CONTINUATION-PV)

oa

Orchestration of human multi-lineage hematopoietic cell development by humanized in vivo bone marrow models

oa

Spironolactone inhibits the NLRP1 inflammasome and alleviates defective erythropoiesis in Diamond-Blackfan anemia

oa

Implementation science in hemato-oncology molecular diagnostics in France via the Groupe des Biologistes Moléculaire des Hémopathies Malignes (GBMHM)

oa

NGS-MRD negativity in post-HSCT ALL spares unnecessary therapeutic interventions triggered by borderline qPCR results without an increase in relapse risk

oa

H1-0 is a specific mediator of the repressive ETV6::RUNX1 transcriptional landscape in preleukemia and B cell acute lymphoblastic leukemia

oa

Patient and physician perceptions regarding treatment expectations and symptomatology in polycythemia vera: Insights from the Landmark 2.0 global health survey

oa

Mastering fate: Redistributing a pioneer protein to rewrite leukemia's script

oa

Models for the marrow: A comprehensive review of AI-based cell classification methods and malignancy detection in bone marrow aspirate smears

oa

Sevuparin strongly reduces hepcidin expression in cells, mice, and healthy human volunteers

oa

IL-11—An aging-related cytokine with opportunities for regulating hematopoiesis

oa

Antibiotic-associated neutropenia is marked by the depletion of intestinal Lachnospiraceae and associated metabolites in pediatric patients

oa

How to diagnose acid sphingomyelinase deficiency (ASMD) and Niemann–Pick disease type C from bone marrow and peripheral blood smears