BCPT Young Investigator's Award Collection 2025

Special Collections
31 January 2025
7 July 2025

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Articles

Open Access

Healthcare Providers' Perspectives on Antidepressant Discontinuation: A Focus Group Study

S. Bouarfa,  Wilma Göttgens,  Suzanne A. Ligthart,  Otto R. Maarsingh,  Christiaan H. Vinkers,  Henricus G. Ruhé,  Pierre M. Bet,  Jacqueline G. Hugtenburg, 
Open Access

Barriers and Facilitators to Pharmacist-Led Deprescribing of Antihypertensives in Long-Term Care: A Survey-Based Study

Ana Vucenovic,  Roni Y. Kraut,  Donna P. Manca,  Cheryl A. Sadowski, 
Open Access

Therapeutic Targeting of the α7 Nicotinic Receptor: Challenges and Prospects for Cognitive Improvement in Alzheimer's and Schizophrenia

Janus H. Magnussen, 

Montelukast Induces Depressive-Like Behaviour in ICR Young Mice Through Oxidative Stress and Inflammatory Response

Shalawate Ayijiang,  Murezati Tiliwaerde,  Yaqi Yang,  Yanlin Li,  Huan Gao,  Jingyi Jia,  Shen Wang,  Qi Liu,  Zengliang Jin, 
Open Access

Foetal Exposure to Phthalates and Endocrine Effects on the Leydig Cell

Sarah Philbert Nielsen,  Line Mathiesen,  Peter Møller, 
Open Access

High Throughput Pharmacovigilance Screening for Roflumilast Adverse Effects in Real-World Settings: A Sequence Symmetry Analysis

Abdullah Abdelaziz,  Charles E. Gaber,  Preeti Gupta,  Todd A. Lee, 
Free Access

Traditional Chinese Medicine for Inhibiting Ferroptosis in Ischemic-Related Diseases

Yukun Zhang,  Yang Yao,  Qiaoling Zhang,  Baoxue Yang, 
Open Access

Poisonings With Opioids and Benzodiazepines in Denmark: A Retrospective Study From the Danish Poison Information Centre

Alba K. V. Sigfredsson,  Dorte Fris Palmqvist,  Kim Dalhoff, 

TCA Cycle Intermediate Mitigates Di(2-ethylhexyl) Phthalate-Induced Cholestatic Liver Injury Through Modulation of the Nrf2/NQO1 Signalling Axis

Yue Jiang,  Fang Xie,  Xutao Ling,  Jiayi Zhang,  Yun Yu,  Qianqian Huang,  Lun Zhang,  Lu Ye,  Wenkang Tao,  Mengzhen Hou,  Cheng Zhang,  Jianqing Wang, 
TCA Cycle Intermediate Mitigates Di(2-ethylhexyl) Phthalate-Induced Cholestatic Liver Injury Through Modulation of the Nrf2/NQO1 Signalling Axis

Open Access

Acetaminophen in Pregnancy: A Population-Level Drug-Utilization Study of Prescription-Based Acetaminophen Use Among Pregnant Women in Denmark From 2001 to 2023

S. Pflugfelder,  E. B. Gram,  P. Damkier, 
Open Access

Maternal Demographic Patterns in Medication use During Pregnancy: A Nationwide Register Study

Mette Østergaard Thunbo,  Julie Hauer Vendelbo,  Daniel R. Witte,  Agnete Larsen,  Lars Henning Pedersen, 

Baicalin Ameliorates L-Glutamate-Induced Hippocampal Oxidative Stress Injury and Apoptosis in Mice by Regulating Nrf2/HO-1 Signalling Pathway

Feng Li,  Zishan Huang,  Huanyu Gou,  Jiarui Zheng,  Mingjiang Yao, 
Open Access

Advances in PET Imaging of α7 Nicotinic Receptors: From Radioligand Development to CNS Applications

Janus H. Magnussen, 
Open Access

Ameliorative Role of β-Caryophyllene on Antioxidant Biomarkers in a Paroxetine-Induced Model of Male Sexual Dysfunction

Elijah Oluwatosin Olopade,  Stephen Adeniyi Adefegha,  Jude Oluwapelumi Alao,  Ayodeji Emmanuel Adepoju,  Aderonke Elizabeth Fakayode,  Ganiyu Oboh, 
Open Access

Could Flumazenil Be Used Pre-hospital by Intramuscular Injection for Coma due to Mixed Drug Overdose Not Responding to Naloxone?: A Systematic Review of the Evidence

Ilinca Farcas,  Lisa Schölin,  Michael Eddleston, 
Open Access

Effects of GLP-1 Receptor Agonists in Alcohol Use Disorder

Mette Kruse Klausen,  Gitte Moos Knudsen,  Tina Vilsbøll,  Anders Fink-Jensen, 
Open Access

In Vivo Investigation of the Effects of Nonylphenol on the Pituitary–Adrenal Axis and Pineal Gland in Male Rats

E. N. İnkaya,  E. Tokgöz,  N. Barlas, 
In Vivo Investigation of the Effects of Nonylphenol on the Pituitary–Adrenal Axis and Pineal Gland in Male Rats

This study aimed to investigate the effect of nonylphenol on the pineal gland and melatonin, together with the pituitary–adrenal axis, which is associated with this system. Nonylphenol has adverse effects on the pituitary–adrenal axis, pineal gland, and melatonin tissues and hormones. Adverse effects have also been observed in liver and kidney tissues. Nonylphenol has a disruptive effect on the endocrine system.

Open Access

Population pharmacokinetic modelling of cetirizine concentrations in human breast milk—A contribution from the ConcePTION project

Erik Melander,  Elisabet I. Nielsen,  Annika Lindqvist,  Markus Hovd,  Peggy Gandia,  Alice Panchaud,  Monia Guidi,  Pieter Annaert,  Pawel Baranczewski,  Olav Spigset,  Hedvig Nordeng, 
Free Access

Diloxanide in amoebiasis management: Unravelling the mechanism of action and effectiveness

Samuel Inshutiyimana,  Michael Matiop Aleu,  Mustaf Aden Abdinoor,  Mariyah Murtaza Janoowalla,  Norhayati Norhayati, 
Open Access

Efflux and uptake transport and gut microbial reactivation of raloxifene glucuronides

Arttu Uoti,  Mika Kurkela,  Mikko Niemi,  Timo Oksanen,  Stefan Oswald,  Lauri Puustinen,  Heidi Kidron,  Noora Sjöstedt, 
Efflux and uptake transport and gut microbial reactivation of raloxifene glucuronides

The enterohepatic recycling of raloxifene likely results from the interplay of gut microbial β-glucuronidases (GUS) and drug transporters expressed in the intestine and the liver. The efflux transporters MRP2 and MRP3 and the uptake transporters OATP1B1, OATP1B3 and OATP2B1 appear to mediate the transport of raloxifene glucuronides in enterocytes and hepatocytes. Gut microbial deglucuronidation of raloxifene glucuronides may represent an additional source of interindividual variability in raloxifene pharmacokinetics.