Gynecological cancer incidence, mortality, and survival among elderly.

Overall health assessment should be performed to formulate individualized glycemic goals and blood glucose control plans. If individualized glycemic goals fail to be achieved, hypoglycemic drugs should be added, besides lifestyle interventions. Therapeutic drug choices should be based on the health status of elderly patients and whether established/high risk factors of atherosclerotic cardiovascular disease (ASCVD), HF, or CKD are present.

Frailty and chronic diseases are interlinked with shared risk factors, pathogenesis, progression and outcome. Timely identification and intervention with incorporation of both pharmacological and non-pharmacological measures are essential to prevent the progression of one to other.

Resistance training is the best intervention in treating the patient with sarcopenic obesity, because it directly focuses on direct muscle bulk improvement by acting on muscle fibers.

Icariin (ICA) exhibits anti-aging effects in different physiological and pathological conditions. ICA displays protective effect against reproductive function decline, neurodegenerative diseases, osteoporosis, intestinal senescence, and cardiovascular aging via anti-inflammation, autophagy induction, antioxidation, maintaining intestinal integrity, and inducing young gut microbiota features.

The COVID-19 pandemic has had a global impact, yet limited attention has been given to the comorbid condition of sarcopenia. This paper explores the shared underlying mechanisms between COVID-19 and sarcopenia and highlights the critical importance of addressing sarcopenia for optimal COVID-19 patient and survivor outcomes. By implementing comprehensive strategies that encompass screening, nutritional interventions, physical activity promotion, psychological support, and community-based initiatives, health experts can effectively control sarcopenia and improve overall well-being in the post-COVID-19 era. Additionally, further research is imperative to deepen our understanding of the relationship between COVID-19 and sarcopenia and to develop evidence-based management approaches.

Strategies for the identification, validation, and application of tumor neoantigens.

Childhood experiences profoundly shape the health, mental well-being, cognitive function, and social relationships of older individuals. From malnutrition and environmental pollutants to trauma and socioeconomic factors, early life significantly influences later-life outcomes, emphasizing the importance of comprehensive support and interventions for the older people.

The English-articles based on artificial intelligence and falls in the older people are both few in number. The number of publications has increased in recent years according to technological developments. In future research, relevant analyzes should be conducted in scientific databases, such as Scopus and PubMed.

Association of hand strength and incontinence by gender. Handgrip strength of < 31 kg in men and < 20.5 kg in women is a risk factor for incontinence, and the risk of incontinence increases with decreasing handgrip strength.