About this book
"A current review of basic research on Rickettsiales biology and pathogenesis in one comprehensive volume.
- Details the scientific knowledge about how these obligate intracellular bacteria invade, survive and replicate inside eukaryotic cells.
- Describes the spectrum of disease caused by an infection and the role of vectors in transmission.
- Discusses protective and pathologic immune responses and establishment of persistent infection.
- Describes the latest developments including genomics and progress in vaccine development.
- Serves as a significant research book for scientists, physicians, medical students, public health professionals, epidemiologists, biocomputational scientists and government policy makers. "
Table of Contents
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CHAPTER 3
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Phylogeny and Comparative Genomics: the Shifting Landscape in the Genomics Era (Pages: 84-141)
CHAPTER 4
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Invasion of the Mammalian Host: Early Events at the Cellular and Molecular Levels (Pages: 142-153)
CHAPTER 6
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Establishing Intracellular Infection: Modulation of Host Cell Functions (Anaplasmataceae) (Pages: 175-220)
CHAPTER 7
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Rickettsial Physiology and Metabolism in the Face of Reductive Evolution (Pages: 221-242)
CHAPTER 8
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Innate Immune Response and Inflammation: Roles in Pathogenesis and Protection (Rickettsiaceae) (Pages: 243-269)
CHAPTER 9
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Innate Immune Response and Inflammation: Roles in Pathogenesis and Protection (Anaplasmataceae) (Pages: 270-303)
CHAPTER 10
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Adaptive Immune Responses to Infection and Opportunities for Vaccine Development (Rickettsiaceae) (Pages: 304-329)
CHAPTER 11
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