The Eicosanoids
Editor(s):
Peter Curtis-Prior,
First published:23 March 2004
Print ISBN:9780471489849 |Online ISBN:9780470020623 |DOI:10.1002/0470020628
Copyright © 2004 John Wiley & Sons, Ltd
About this book
This comprehensive reference work, updated from the first edition, brings together the knowledge and expertise of contributors from around the world. It includes new topics such as prostaglandin synthetase enzyme, new synthetic eicosanoids, innovative analytical methods, the influence of cytokines in the regulation of synthesis and actions, newer eicosanoids that influence the cardiovascular system, and newly discovered roles in reproduction and interactions with nitric oxide.
This book satisfies a surge of interest in prostaglandins—NSAIDS (e.g. aspirin) are the biggest selling drugs of all time, and the field has been refreshed by the advent of new types (selective COX-2 inhibitors, anti-leukotiene drugs).
Reviews
"Investigators with either or a basic or clinical interest in the metabolism of essential fatty acids and eicosanoid production have all such information at hand in this excellent compendium." (New England Journal of Medicine, March 17, 2005)
"…it serves to effectively communicate the most current information on eicosanoids in an understandable manner.” (E-STREAMS, September 2004)
Author Bios
Peter Curtis-Prior is the editor of The Eicosanoids, published by Wiley.
Table of Contents
Export Citations
CHAPTER 2
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Control of Eicosanoid Production by Cellular and Secreted Phospholipase A2 (Pages: 17-27)
CHAPTER 3
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Mechanisms of PGH Synthase-1 (COX-1) Activity and Role of Radical States (Pages: 29-42)
CHAPTER 6
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Biosynthesis and Biological Effects of 5-oxo-ETE and Other Oxoeicosatetraenoic Acids (Pages: 61-68)
CHAPTER 9
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Enzyme Immunoassays of Metabolites and Enzymes Using Acetylcholinesterase as Label (Pages: 103-109)
CHAPTER 13
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Perspectives and Clinical Significance of the Biochemical and Molecular Pharmacology of Eicosanoids (Pages: 129-162)
CHAPTER 15
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Biosynthesis and Degradation of Anandamide, An Endogenous Ligand of Cannabinoid Receptors (Pages: 179-187)
CHAPTER 18
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Insight into Prostanoid Functions: Lessons from Receptor-Knockout Mice (Pages: 219-225)
CHAPTER 19
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Perspectives and Clinical Significance of Eicosanoids in Immunology, Endocrinology and Metabolic Regulation (Pages: 227-236)
CHAPTER 24
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Molecular Regulation of Pancreatic Islet Prostaglandin Synthesis and Its Relevance to Diabetes Mellitus (Pages: 277-287)
CHAPTER 27
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Perspectives and Clinical Significance of Eicosanoids in Pain and Inflammation (Pages: 319-325)
CHAPTER 32
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Perspectives and Clinical Significance of Eicosanoids in the Circulatory System (Pages: 359-371)
CHAPTER 34
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Generation of Vasoactive Prostanoids by the Cyclooxygenase-2 Pathway in the Cardiovascular System of the Rat (Pages: 387-392)
CHAPTER 35
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Eicosanoid Generation and Effects in Cardiac Muscle and Coronary Vessels (Pages: 393-404)
CHAPTER 36
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Perspectives and Clinical Significance of Eicosanoids in the Digestive System (Pages: 405-414)
CHAPTER 42
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Arachidonate Metabolites in the Neurophysiological System: The Fever Pathway (Pages: 463-472)
CHAPTER 47
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Essential Fatty Acids: Eicosanoid Precursors in the Treatment of Huntington's Disease (Pages: 499-506)
CHAPTER 48
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Perspectives and Clinical Significance of Eicosanoids in Obstetric and Gynaecological Practice (Pages: 507-515)
CHAPTER 54
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Biochemical Interactions of Platelet-Activating Factor with Eicosanoids (Pages: 583-592)
CHAPTER 56
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