Chapter 41

Eicosanoid Pathways in the Ageing of the Central Nervous System

Hari Manev

Hari Manev

The Psychiatric Institute, Department of Psychiatry, University of Illinois at Chicago, 1601 West Taylor Street, Chicago, IL 60612, USA

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Tolga Uz

Tolga Uz

The Psychiatric Institute, Department of Psychiatry, University of Illinois at Chicago, 1601 West Taylor Street, Chicago, IL 60612, USA

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First published: 23 March 2004

Summary

This chapter contains sections titled:

  • Eicosanoid Pathways and Cell Proliferation: Relevant for Neurogenesis?

  • Glucocorticoids and Neuronal Eicosanoid Pathways

  • Epigenetic Mechanisms and Eicosanoid Pathways

  • Transgenic Mice to Study Brain 5-LOX and COX-2

  • 5-LOX and COX-2 in the Pathobiology of Neurodegeneration

  • The CNS Eicosanoid Pathways as a Putative “Anti-ageing” Drug Target

  • Acknowledgement

  • References

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