Chapter 15

Biosynthesis and Degradation of Anandamide, An Endogenous Ligand of Cannabinoid Receptors

Natsuo Ueda

Natsuo Ueda

Department of Biochemistry, Kagawa University School of Medicine, Miki-cho, Kita-gun, Kagawa 761-0793, Japan

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Dale G. Deutsch

Dale G. Deutsch

Department of Biochemistry and Cell Biology, State University of New York at Stony Brook, Stony Brook, NY 11794-5215, USA

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First published: 23 March 2004
Citations: 1

Summary

This chapter contains sections titled:

  • Occurrence and Biological Activities of Long-chain N-acylethanolamines

  • Biosynthetic Routes of Anandamide and Other N-acylethanolamines

  • N-acyltransferase

  • Phosphodiesterase

  • Degradation of Anandamide and Other Long-chain N-acylethanolamines

  • Catalytic Properties of Fatty Acid Amide Hydrolase

  • Molecular Properties of FAAH

  • An Acid Amidase That Hydrolyses Anandamide and Other N-acylethanolamines

  • Oxygenation of Anandamide

  • Perspectives

  • References

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