• Issue
    2012
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Editorial
Open Access

Expansion of the Genetic Alphabet: Unnatural Nucleobases and Their Applications

Subhendu Sekhar Bag,  Jennifer M. Heemstra,  Yoshio Saito,  David M. Chenoweth, 
  • First Published: 17 December 2012
Review Article
Open Access

Lighting Up RNA-Cleaving DNAzymes for Biosensing

Kha Tram,  Pushpinder Kanda,  Yingfu Li, 
  • First Published: 08 November 2012
Research Article
Open Access

Plant MicroRNA Prediction by Supervised Machine Learning Using C5.0 Decision Trees

Philip H. Williams,  Rod Eyles,  Georg Weiller, 
  • First Published: 07 November 2012

Review Article
Open Access

Specific Roles of MicroRNAs in Their Interactions with Environmental Factors

Juan Wang,  Qinghua Cui, 
  • First Published: 31 October 2012
Review Article
Open Access

Dioxaphosphorinane-Constrained Nucleic Acid Dinucleotides as Tools for Structural Tuning of Nucleic Acids

Dan-Andrei Catana,  Brice-Loïc Renard,  Marie Maturano,  Corinne Payrastre,  Nathalie Tarrat,  Jean-Marc Escudier, 
  • First Published: 24 October 2012
Review Article
Open Access

Challenges and Opportunities for Small Molecule Aptamer Development

Maureen McKeague,  Maria C. DeRosa, 
  • First Published: 24 October 2012
Review Article
Open Access

Genetically Encoded Libraries of Nonstandard Peptides

Takashi Kawakami,  Hiroshi Murakami, 
  • First Published: 14 October 2012
Research Article
Open Access

Nucleic-Acid-Binding Chromophores as Efficient Indicators of Aptamer-Target Interactions

Kwabena Sarpong,  Bhaskar Datta, 
  • First Published: 10 October 2012
Review Article
Open Access

Potential of Peptides as Inhibitors and Mimotopes: Selection of Carbohydrate-Mimetic Peptides from Phage Display Libraries

Teruhiko Matsubara, 
  • First Published: 10 October 2012
Review Article
Open Access

Artificial Specific Binders Directly Recovered from Chemically Modified Nucleic Acid Libraries

Yuuya Kasahara,  Masayasu Kuwahara, 
  • First Published: 08 October 2012
Research Article
Open Access

Functional Annotation of Small Noncoding RNAs Target Genes Provides Evidence for a Deregulated Ubiquitin-Proteasome Pathway in Spinocerebellar Ataxia Type 1

Stephan Persengiev,  Ivanela Kondova,  Ronald E. Bontrop, 
  • First Published: 03 October 2012
Research Article
Open Access

UvrD Participation in Nucleotide Excision Repair Is Required for the Recovery of DNA Synthesis following UV-Induced Damage in Escherichia coli

Kelley N. Newton,  Charmain T. Courcelle,  Justin Courcelle, 
  • First Published: 27 September 2012
Research Article
Open Access

Superior Silencing by 2′,4′-BNANC-Based Short Antisense Oligonucleotides Compared to 2′,4′-BNA/LNA-Based Apolipoprotein B Antisense Inhibitors

Tsuyoshi Yamamoto,  Hidenori Yasuhara,  Fumito Wada,  Mariko Harada-Shiba,  Takeshi Imanishi,  Satoshi Obika, 
  • First Published: 26 September 2012
Research Article
Open Access

Imaging mRNA Expression in Live Cells via PNA·DNA Strand Displacement-Activated Probes

Zhenghui Wang,  Ke Zhang,  Karen L. Wooley,  John-Stephen Taylor, 
  • First Published: 26 September 2012
Research Article
Open Access

In Vitro Selection of Fab Fragments by mRNA Display and Gene-Linking Emulsion PCR

Takeshi Sumida,  Hiroshi Yanagawa,  Nobuhide Doi, 
  • First Published: 23 September 2012
Research Article
Open Access

Inhibition of HIV Replication by Cyclic and Hairpin PNAs Targeting the HIV-1 TAR RNA Loop

Gregory Upert,  Audrey Di Giorgio,  Alok Upadhyay,  Dinesh Manvar,  Nootan Pandey,  Virendra N. Pandey,  Nadia Patino, 
  • First Published: 17 September 2012
Research Article
Open Access

Alternative Splicing of a Novel Inducible Exon Diversifies the CASK Guanylate Kinase Domain

Jill A. Dembowski,  Ping An,  Maritsa Scoulos-Hanson,  Gene Yeo,  Joonhee Han,  Xiang-Dong Fu,  Paula J. Grabowski, 
  • First Published: 12 September 2012
Review Article
Open Access

Practical Tips for Construction of Custom Peptide Libraries and Affinity Selection by Using Commercially Available Phage Display Cloning Systems

Keisuke Fukunaga,  Masumi Taki, 
  • First Published: 09 September 2012
Review Article
Open Access

Recent Advances in Chemical Modification of Peptide Nucleic Acids

Eriks Rozners, 
  • First Published: 06 September 2012
Research Article
Open Access

Allelic Imbalance in TOR1A mRNA Expression in Manifesting and Non-Manifesting Carriers of the GAG-Deletion

Ioanna A. Armata,  Andreas I. Diplas,  Laurie J. Ozelius,  Pullanipally Shashidharan, 
  • First Published: 03 September 2012
Research Article
Open Access

A Two-Piece Derivative of a Group I Intron RNA as a Platform for Designing Self-Assembling RNA Templates to Promote Peptide Ligation

Takahiro Tanaka,  Hiroyuki Furuta,  Yoshiya Ikawa, 
  • First Published: 22 August 2012
Research Article
Open Access

Combinatorial Synthesis, Screening, and Binding Studies of Highly Functionalized Polyamino-amido Oligomers for Binding to Folded RNA

Jonathan K. Pokorski,  Daniel H. Appella, 
  • First Published: 21 August 2012
Review Article
Open Access

Directed Evolution of Proteins through In Vitro Protein Synthesis in Liposomes

Takehiro Nishikawa,  Takeshi Sunami,  Tomoaki Matsuura,  Tetsuya Yomo, 
  • First Published: 16 August 2012
Research Article
Open Access

A Concept for Selection of Codon-Suppressor tRNAs Based on Read-Through Ribosome Display in an In Vitro Compartmentalized Cell-Free Translation System

Atsushi Ogawa,  Masayoshi Hayami,  Shinsuke Sando,  Yasuhiro Aoyama, 
  • First Published: 13 August 2012
Research Article
Open Access

Structural and Functional Characterization of RecG Helicase under Dilute and Molecular Crowding Conditions

Sarika Saxena,  Satoru Nagatoishi,  Daisuke Miyoshi,  Naoki Sugimoto, 
  • First Published: 08 August 2012
Research Article
Open Access

Genetic Predisposition for Dermal Problems in Hexavalent Chromium Exposed Population

Priti Sharma,  Vipin Bihari,  Sudhir K. Agarwal,  Sudhir K. Goel, 
  • First Published: 26 July 2012
Review Article
Open Access

Unwinding and Rewinding: Double Faces of Helicase?

Yuliang Wu, 
  • First Published: 19 July 2012
Research Article
Open Access

Convenient and Scalable Synthesis of Fmoc-Protected Peptide Nucleic Acid Backbone

Trevor A. Feagin,  Nirmal I. Shah,  Jennifer M. Heemstra, 
  • First Published: 10 July 2012
Research Article
Open Access

PCR Amplification and Transcription for Site-Specific Labeling of Large RNA Molecules by a Two-Unnatural-Base-Pair System

Michiko Kimoto,  Rie Yamashige,  Shigeyuki Yokoyama,  Ichiro Hirao, 
  • First Published: 26 June 2012
Review Article
Open Access

Small RNA Expression Profiling by High-Throughput Sequencing: Implications of Enzymatic Manipulation

Fanglei Zhuang,  Ryan T. Fuchs,  G. Brett Robb, 
  • First Published: 20 June 2012
Research Article
Open Access

Expression Profiling of a Heterogeneous Population of ncRNAs Employing a Mixed DNA/LNA Microarray

Konstantinia Skreka,  Marek Zywicki,  Michael Karbiener,  Alexander Hüttenhofer,  Marcel Scheideler,  Mathieu Rederstorff, 
  • First Published: 10 June 2012
Review Article
Open Access

Synthetic Nucleotides as Probes of DNA Polymerase Specificity

Jason M. Walsh,  Penny J. Beuning, 
  • First Published: 07 June 2012
Editorial
Open Access

Alternative Splicing and Cancer

Didier Auboeuf,  Maria Carmo-Fonseca,  Juan Valcarcel,  Giuseppe Biamonti, 
  • First Published: 20 May 2012
Research Article
Open Access

Features of “All LNA” Duplexes Showing a New Type of Nucleic Acid Geometry

Charlotte Förster,  André Eichert,  Dominik Oberthür,  Christian Betzel,  Reinhard Geßner,  Andreas Nitsche,  Jens P. Fürste, 
  • First Published: 14 May 2012
Research Article
Open Access

Metal Ion Chelates as Surrogates of Nucleobases for the Recognition of Nucleic Acid Sequences: The Pd2+ Complex of 2,6-Bis(3,5-dimethylpyrazol-1-yl)purine Riboside

Sharmin Taherpour,  Tuomas Lönnberg, 
  • First Published: 13 May 2012
Research Article
Open Access

MsDpo4—a DinB Homolog from Mycobacterium smegmatis—Is an Error-Prone DNA Polymerase That Can Promote G:T and T:G Mismatches

Amit Sharma,  Deepak T. Nair, 
  • First Published: 15 March 2012
Editorial
Open Access

Using Chemical Approaches to Understand RNA Structure and Function in Biology

Dmitry A. Stetsenko,  Arthur van Aerschot, 
  • First Published: 16 February 2012
Research Article
Open Access

Straightforward Procedure for Laboratory Production of DNA Ladder

Vo Thi Thuong Lan,  Pham Thi Thanh Loan,  Pham Anh Thuy Duong,  Le Thi Thanh,  Ngo Thi Ha,  Ta Bich Thuan, 
  • First Published: 12 February 2012
Review Article
Open Access

Chemical Approaches for Structure and Function of RNA in Postgenomic Era

Tae Suk Ro-Choi,  Yong Chun Choi, 
  • First Published: 12 January 2012
Review Article
Open Access

Alternative Splicing of Fibroblast Growth Factor Receptor IgIII Loops in Cancer

Klaus Holzmann,  Thomas Grunt,  Christine Heinzle,  Sandra Sampl,  Heinrich Steinhoff,  Nicole Reichmann,  Miriam Kleiter,  Marlene Hauck,  Brigitte Marian, 
  • First Published: 12 December 2011
Review Article
Open Access

Splicing Programs and Cancer

Sophie Germann,  Lise Gratadou,  Martin Dutertre,  Didier Auboeuf, 
  • First Published: 24 October 2011
Review Article
Open Access

VEGF Spliced Variants: Possible Role of Anti-Angiogenesis Therapy

Caroline Hilmi,  Mélanie Guyot,  Gilles Pagès, 
  • First Published: 13 October 2011
Review Article
Open Access

p53 Family: Role of Protein Isoforms in Human Cancer

Jinxiong Wei,  Elena Zaika,  Alexander Zaika, 
  • First Published: 09 October 2011
Review Article
Open Access

Alternative Splicing in Oncogenic Kinases: From Physiological Functions to Cancer

Sabine Druillennec,  Coralie Dorard,  Alain Eychène, 
  • First Published: 05 October 2011