• Issue

    Rheumatology & Autoimmunity: Volume 3, Issue 1

    1-65
    March 2023

ISSUE INFORMATION

Open Access

Issue Information

  • First Published: 27 March 2023

REVIEWS

Open Access

Perceptions into causes and consequences of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants

  • Pages: 1-8
  • First Published: 27 February 2023
Perceptions into causes and consequences of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants

Graphical description of molecular mechanisms involved in the induction of mutations in severe acute respiratory syndrome coronavirus 2 genomes in the host cellular milieu, which are responsible for the emergence of variants.

Open Access

Origins and history of autoimmunity—A brief review

  • Pages: 9-14
  • First Published: 21 September 2022
Origins and history of autoimmunity—A brief review

The origin and history of autoimmunity and autoimmune diseases.

ORIGINAL ARTICLES

Open Access

Immunophenotyping identifies distinct cellular signatures for systemic lupus erythematosus and lupus nephritis

  • Pages: 15-25
  • First Published: 23 November 2022
Immunophenotyping identifies distinct cellular signatures for systemic lupus erythematosus and lupus nephritis

Flow cytometric analysis of circulating lymphocytes was used to examine the differences in cell populations between SLE patients with or without nephritis and healthy blood donors.

Open Access

Impact of pretransplant asplenia vaccination on anti-A/B antibody titers in prospective ABO incompatible kidney transplant recipients

  • Pages: 26-34
  • First Published: 10 January 2023
Impact of pretransplant asplenia vaccination on anti-A/B antibody titers in prospective ABO incompatible kidney transplant recipients

Vaccination before transplantation is recommended. Pneumococcal vaccines contain A/B blood group antigens which might increase anti-A/B titers. Potential ABO incompatible transplant recipients were assessed for a rise in anti-A/B titers following asplenia vaccination (including against pneumococcus). There was no clinically relevant rise in anti-A/B titers following vaccination. No transplant was delayed or cancelled due to a rise in titers following vaccination.

Open Access

Long-term prognosis of focal segmental glomerulosclerosis treated with therapeutic low-density lipoprotein-apheresis in patients with severe kidney dysfunction and proteinuria

  • Pages: 35-42
  • First Published: 27 March 2023
Long-term prognosis of focal segmental glomerulosclerosis treated with therapeutic low-density lipoprotein-apheresis in patients with severe kidney dysfunction and proteinuria

The prognosis of focal segmental glomerulosclerosis (FSGS) patients with nephrotic syndrome is poor. We investigated the effectiveness of treatment in 50 patients with primary FSGS. Low-density lipoprotein-apheresis (LDL-A) was performed in 4 patients who presented with steroid-resistant nephrotic syndrome. In comparison with 17 patients who did not receive LDL-A after 1989, the LDL-A group had higher urinary protein excretion (13.7 vs. 5.2 g/day, P = 0.053) and serum creatinine (4.11 vs. 1.65 mg/dL) levels at onset. Nevertheless, the LDL-A group showed a numerically higher remission rate (75% vs. 59%) compared with the nonlipoprotein-apheresis group.

CASE REPORTS

Open Access

Phenotypical statin-associated immune-mediated necrotizing myositis with histological features of inclusion body myositis

  • Pages: 50-55
  • First Published: 24 November 2022
Phenotypical statin-associated immune-mediated necrotizing myositis with histological features of inclusion body myositis

Statin-associated immune-mediated necrotizing myositis versus inclusion body myositis: A comparison

Open Access

Acute kidney injury following autoimmune hemolytic anemia due to simultaneous use of ciprofloxacin and hydrochlorothiazide: A case report and review of the literature

  • Pages: 56-62
  • First Published: 27 February 2023
Acute kidney injury following autoimmune hemolytic anemia due to simultaneous use of ciprofloxacin and hydrochlorothiazide: A case report and review of the literature

The mechanisms by which drugs induce immune hemolytic anemia are classified into drug-dependent and drug-independent categories.