• Issue

    HemaSphere: Volume 7, Issue 10

    October 2023
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Article

Open Access

High-throughput Proteomics Identifies THEMIS2 as Independent Biomarker of Treatment-free Survival in Untreated CLL

Paul J. Hengeveld,  P. Martijn Kolijn,  Jeroen A.A. Demmers,  Wouter Doff,  Julie M.N. Dubois,  Melissa Rijken,  Jorn L.J.C. Assmann,  Lina van der Straten,  Henk Jan Boiten,  Kirsten J. Gussinklo,  Peter J.M. Valk,  Laura M. Faber,  Peter E. Westerweel,  Arnon P. Kater,  Mark-David Levin,  Anton W. Langerak, 
  • First Published: 01 October 2023
High-throughput Proteomics Identifies THEMIS2 as Independent Biomarker of Treatment-free Survival in Untreated CLL

Open Access

Thiotepa-busulfan-fludarabine Compared to Treosulfan-based Conditioning for Haploidentical Transplant With Posttransplant Cyclophosphamide in Patients With Acute Myeloid Leukemia in Remission: A Study From the Acute Leukemia Working Party of the EBMT

Francesco Saraceni,  Myriam Labopin,  Anna M. Raiola,  Didier Blaise,  Péter Reményi,  Federica Sorà,  Jiri Pavlu,  Stefania Bramanti,  Alessandro Busca,  Ana Berceanu,  Giorgia Battipaglia,  Giuseppe Visani,  Gerard Sociè,  Gesine Bug,  Caterina Micò,  Giorgio La Nasa,  Maurizio Musso,  Attilio Olivieri,  Alexandros Spyridonidis,  Bipin Savani,  Fabio Ciceri,  Arnon Nagler,  Mohamad Mohty,  on behalf of the Acute Leukemia Working Party (ALWP) of the European Society for Blood and Marrow Transplantation (EBMT) , 
  • First Published: 01 October 2023
Thiotepa-busulfan-fludarabine Compared to Treosulfan-based Conditioning for Haploidentical Transplant With Posttransplant Cyclophosphamide in Patients With Acute Myeloid Leukemia in Remission: A Study From the Acute Leukemia Working Party of the EBMT

Perspective

Open Access

Current and Future Perspective in Hematopoietic Stem Progenitor Cell-gene Therapy for Inborn Errors of Metabolism

Francesca Tucci,  Giulia Consiglieri,  Matilde Cossutta,  Maria Ester Bernardo, 
  • First Published: 01 October 2023

Letter

Open Access

Real-world Data: MCL2 Protocol Demonstrates Excellent Treatment Results Among Patients With Mantle Cell Lymphoma Not Fulfilling the Original Trial Inclusion Criteria

Minna Harmanen,  Tuula Klaavuniemi,  Marc Sorigue,  Madiha Khan,  Roosa Prusila,  Esa Kari,  Erika Alanne,  Aino Rajamäki,  Kaisa Sunela,  Arja Jukkola,  Esa Jantunen,  Juan-Manuel Sancho,  Sanna Ketola,  Hanne Kuitunen,  Tuomas Selander,  Aino Rönkä,  Outi Kuittinen, 
  • First Published: 01 October 2023

HemaTopics

Open Access

Flavor of Iron at EHA2023: Novel Regulatory Mechanisms and Therapeutic Options for the Correction of Anemia

Francesca Vinchi,  Michela Asperti,  Oriana Marques,  Antonella Nai,  Laura Silvestri, 
  • First Published: 01 October 2023

Letter

Open Access

Clonal Hematopoiesis Defined by Somatic Mutations Infrequently Co-occurs With Mosaic Loss of the Y Chromosome in a Population-based Cohort

Priscilla Kamphuis,  Isabelle A. van Zeventer,  Aniek O. de Graaf,  Giulio Genovese,  Jonas B. Salzbrunn,  Avinash G. Dinmohamed,  Bert A. van der Reijden,  Jan Jacob Schuringa,  Joop H. Jansen,  Gerwin Huls, 
  • First Published: 01 October 2023

Article

Open Access

Clinical Implications and Dynamics of Clonal Hematopoiesis in Anti-CD19 CAR T-cell Treated Patients

Victoria Panagiota,  Johanna Franziska Kerschbaum,  Olaf Penack,  Catarina M. Stein,  Christopher M. Arends,  Christian Koenecke,  Paulina M. Strzelecka,  Arnold Kloos,  Laura Wiegand,  Alina Lasch,  Robert Altwasser,  Adriane Halik,  Razif Gabdoulline,  Julia Thomson,  Konstantin Weibl,  Georg-Nikolaus Franke,  Carolina Berger,  Justin Hasenkamp,  Francis Ayuk,  Il-Kang Na,  Gernot Beutel,  Ulrich Keller,  Lars Bullinger,  Gerald Georg Wulf,  Nicolaus Kröger,  Vladan Vucinic,  Michael Heuser,  Frederik Damm, 
  • First Published: 01 October 2023
Clinical Implications and Dynamics of Clonal Hematopoiesis in Anti-CD19 CAR T-cell Treated Patients

Open Access

CSF3R T618I Collaborates With RUNX1-RUNX1T1 to Expand Hematopoietic Progenitors and Sensitizes to GLI Inhibition

Anja S. Swoboda,  Vanessa C. Arfelli,  Anna Danese,  Roland Windisch,  Paul Kerbs,  Enric Redondo Monte,  Johannes W. Bagnoli,  Linping Chen-Wichmann,  Alessandra Caroleo,  Monica Cusan,  Stefan Krebs,  Helmut Blum,  Michael Sterr,  Wolfgang Enard,  Tobias Herold,  Maria Colomé-Tatché,  Christian Wichmann,  Philipp A. Greif, 
  • First Published: 01 October 2023
CSF3R T618I Collaborates With RUNX1-RUNX1T1 to Expand Hematopoietic Progenitors and Sensitizes to GLI Inhibition

Review Article

Open Access

EVI1-mediated Programming of Normal and Malignant Hematopoiesis

Susanne Lux,  Michael D. Milsom, 
  • First Published: 01 October 2023

Article

Open Access

Machine Learning Improves Risk Stratification in Myelodysplastic Neoplasms: An Analysis of the Spanish Group of Myelodysplastic Syndromes

Adrian Mosquera Orgueira,  Manuel Mateo Perez Encinas,  Nicolas A Diaz Varela,  Elvira Mora,  Marina Díaz-Beyá,  María Julia Montoro,  Helena Pomares,  Fernando Ramos,  Mar Tormo,  Andres Jerez,  Josep F Nomdedeu,  Carlos De Miguel Sanchez,  Arenillas Leonor,  Paula Cárcel,  Maria Teresa Cedena Romero,  Blanca Xicoy,  Eugenia Rivero,  Rafael Andres del Orbe Barreto,  Maria Diez-Campelo,  Luis E. Benlloch,  Davide Crucitti,  David Valcárcel, 
  • First Published: 01 October 2023
Machine Learning Improves Risk Stratification in Myelodysplastic Neoplasms: An Analysis of the Spanish Group of Myelodysplastic Syndromes

Letter

Open Access

All-CLL: A Capture-based Next-generation Sequencing Panel for the Molecular Characterization of Chronic Lymphocytic Leukemia

Irene López-Oreja,  Mónica López-Guerra,  Juan Correa,  Pablo Mozas,  Ana Muntañola,  Luz Muñoz,  Ana-Camino Salgado,  Sílvia Ruiz-Gaspà,  Dolors Costa,  Sílvia Beà,  Pedro Jares,  Elías Campo,  Dolors Colomer,  Ferran Nadeu, 
  • First Published: 01 October 2023
Open Access

Waldenström Macroglobulinemia in Very Elderly (≥75-year-old) Patients: A 33-year-retrospective Cohort Study in an Italian University Hospital

Nicolò Danesin,  Mariella Lo Schirico,  Greta Scapinello,  Angela Grassi,  Marcello Riva,  Tamara Berno,  Antonio Branca,  Andrea Visentin,  Marco Carraro,  Laura Pavan,  Sabrina Manni,  Laura Bonaldi,  Annalisa Martines,  Roberta Bertorelle,  Fabrizio Vianello,  Carmela Gurrieri,  Chiara Briani,  Renato Zambello,  Livio Trentin,  Francesco Piazza, 
  • First Published: 01 October 2023
Open Access

ABL-class Genomic Breakpoint Q-PCR: A Patient-specific Approach for MRD Monitoring in Acute Lymphoblastic Leukemia

Inge van Outersterp,  Vincent H.J. van der Velden,  Patricia G. Hoogeveen,  Goda E. Vaitkevičienė,  Edwin Sonneveld,  Gijs van Haaften,  Roland P. Kuiper,  Udo zur Stadt,  Gabriele Escherich,  Judith M. Boer,  Monique L. den Boer, 
  • First Published: 01 October 2023

Correction Notice

Open Access

Correction Notice: Impact of T-cell Receptor Status on Mutational Landscape and Outcome in T-ALL

  • First Published: 01 October 2023