Recurrent Clostridium difficile infections are becoming more prevalent, and new methods of treatment are being encouraged, such as fecal microbiota transplantation. In our manuscript, we show that fecal microbiota transplantation is an effective means of treating recurrent Clostridium difficile infections.

The aim of this study was to evaluate the efficacy and adverse events (AEs) of sorafenib therapy in a Chinese population diagnosed with hepatocellular carcinoma (HCC), and the results found that sorafenib-related AEs, including HFSR, hypertension, and diarrhea, can predict positive therapy efficacy to HCC.

The common and independent genes might be associated with the progression and hepatocarcinogenesis of ALD and NAFLD.

Propofol should replace midazolam in our endoscopic units, especially for cirrhotic patients that are scheduled to undergo upper GI endoscopy.

In this prospective study, multiplex PCR using specific primers for genes IS6110, MPB64, and Protein b had a higher sensitivity compared to conventional techniques for the diagnosis of gastrointestinal tuberculosis.

We have developed a nomogram that could accurately predict extrahepatic metastasis of hepatocellular carcinoma (HCC) and be readily available for formulating individualized treatment for all individual HCC patients to improve therapeutic efficacy.

Ileocecal thickening is frequently reported on computed tomography. The clinical and endoscopic significance of this is uncertain. In this study of 50 patients, we have shown that the majority of patients have an underlying disease, and therefore, these patients should undergo ileocolonoscopy.

Direct-acting antivirals did not increase the rate of hepatocellular carcinoma (HCC), even in immunosuppressed patients. However, careful follow-up for HCC recurrence is required in previously treated cases.

The study was a retrospective cohort analysis of patients hospitalized for colonoscopic polypectomy. A total of 1962 polyps were detected in patients and they underwent polypectomy; hemorrhage occurred in 41 cases. A correlation was demonstrated between postpolypectomy hemorrhage and each of the following factors: polyp size and operative modality.

We studied the feasibility and outcome of SEMS placement using side- and forward-viewing endoscopes. Technical and clinical success, complication rate between side- and forward-viewing endoscopes were comparable. However, SEMS could be placed in shorter time using forward- rather than side-viewing endoscope.

Acute lung injury is an important cause of mortality in the setting of severe acute pancreatitis. Besides lung involvement, acute and chronic pancreatitis may also lead to the involvement of other thoracic compartments including mediastinum, pleura, and vascular structures. In this review, we discuss the thoracic complications of pancreatitis including lung, pleural, mediastinal and vascular manifestations.

Pancreatic necrosis is associated with high mortality and morbidity. Here, we review the literature and update the concepts of endoscopic therapy of pancreatic necrosis.

After ingestion, fasciola metacercariae penetrate the duodenal wall, migrate through the peritoneal cavity and enter the liver. After a period migrating randomly through the liver parenchyma, they eventually reach the larger biliary ducts and mature into adults. We present a case that illustrates this migration route of Fasciola.

A 62-year-old lady with bilio-enteric communication presented as case of chronic diarrhea. Computed tomography revealed adherence of gallbladder to adjacent transverse colon. Hepatobiliary scintigraphy demonstrated the presence of a cholecystocolic fistula.

Single-operator cholangioscopy (SOC) is a valuable diagnostic (e.g. stricture) and therapeutic (e.g. lithotripsy) platform for treatment of complex biliary diseases. Technical success rates, i.e. advancement up to a pre-defined target lesion, are generally high. Anatomic factors, such as periampullary diverticula, however, may complicate scope insertion, for which a novel troubleshooter technique, designated the “long scope position insertion”, is presented here.