• Issue

    Immunity, Inflammation and Disease: Volume 13, Issue 7

    publicationMeta
    July 2025

ISSUE INFORMATION

Open Access

Issue Information

  • First Published: 08 July 2025

ORIGINAL ARTICLE

Open Access

APOBEC3C-Mediated NF-κB Activation Promotes Malignant Progression of Gliomas

  • First Published: 24 July 2025
APOBEC3C-Mediated NF-κB Activation Promotes Malignant Progression of Gliomas

The results of this study suggest that high expression of APOBEC3C is associated with poor prognosis in glioma and may affect immune regulation. Knocking down APOBEC3C can inhibit the invasion and migration abilities of glioma cells. In addition, APOBEC3C can regulate the activation of the NF-κB signaling pathway, which is expected to be a target for improving immunotherapy in glioma patients.

Open Access

Fatty Acids and Inflammatory Protein Biomarkers From Coronavirus Disease 2019 Patients

  • First Published: 08 July 2025
Fatty Acids and Inflammatory Protein Biomarkers From Coronavirus Disease 2019 Patients

The coronavirus disease 2019 (COVID-19) pandemic created the need to identify new biomarkers and drug targets. In this study, we aimed to establish a unique signature profile of specific fatty acids, cytokines, and chemokines present in the plasma after COVID-19 viral infection to serve as novel biomarkers that can be used to determine the severity of infection, disease prognosis, and consideration for therapeutic options.

REVIEW ARTICLE

Open Access

Molecular Mechanism of NLRP3 Inflammasome in Inflammatory Diseases and Tumors

  • First Published: 16 July 2025
Molecular Mechanism of NLRP3 Inflammasome in Inflammatory Diseases and Tumors

My review paper described the struction of NLRP3 inflammasomes and the actived mechanism of them. Then, sumerized the NLRP3 inflammasomes' function of inflammatory diseases and cancer.

ORIGINAL ARTICLE

Open Access

The Importance of Pan-Immune-Inflammation Value Score in Locally Advanced Rectal Cancer

  • First Published: 24 July 2025
The Importance of Pan-Immune-Inflammation Value Score in Locally Advanced Rectal Cancer

PIV score is a prognostic marker for rectal cancer. It can be used in the selection of high-risk patients.

Open Access

Inflammatory Responses Potentiate GAS M Protein Induced Cardiac Damage in an Experimental Model of Rheumatic Heart Disease

  • First Published: 11 July 2025
Inflammatory Responses Potentiate GAS M Protein Induced Cardiac Damage in an Experimental Model of Rheumatic Heart Disease

Group A streptococcal M protein elicit antibody and T-cell responses that cross react with cardiac and connective tissue proteins in the Rat Autoimmune Valvulitis (RAV) model of rheumatic heart disease. Bordetella pertussis Toxin induce a robust Th1 response that potentiates the autoimmune process in the RAV model A robust Th1/Th17 response was found to be a major driver of cardiac pathology in the RAV model