Association of clonal haematopoiesis of indeterminate potential (CHIP) with incident heart failure (HF).

Serial changes in pulmonary artery wedge pressure (PAWP) and PAWP to Qs slopes in adult Fontan patients, heart failure with preserved ejection fraction (HFpEF) and non-cardiac dyspnoea (NCD) (p-values in red correspond to differences between Fontan and HFpEF patients while those in gray correspond to differences between Fontan and NCD for each phase).

Association between patient-reported symptoms and markers of congestion. AHF, acute heart failure; IVC, inferior vena cava; JVD, jugular venous distention; KCCQ-TSS, Kansas City Cardiomyopathy Questionnaire total symptom score; NRS, numeric rating scale; NT-proBNP, N-terminal pro-B-type natriuretic peptide; TR, tricuspid regurgitation.

Atrial fibrillation in heart failure with mildly reduced and preserved ejection fraction. AF, atrial fibrillation; CI, confidence interval; GWTG-HF, Get With The Guidelines-Heart Failure; HF, heart failure; HFmrEF, heart failure with mildly reduced ejection fraction; HFpEF, heart failure with preserved ejection fraction; HR, hazard ratio.

In intention-to-treat analyses, early routine catheter ablation (CA) resulted in similar long-term outcomes to a delayed selective CA strategy in patients with persistent or long-standing persistent atrial fibrillation (AF) and symptomatic heart failure with reduced ejection fraction (HFrEF) enrolled in the ARC-HF and CAMTAF clinical trials. Medical therapy refers to pharmacological rate control. Kaplan–Meier survival curves shown for all-cause death (left) and a composite outcome of all-cause death or cardiovascular (CV) hospitalization (right). CI, confidence interval; HR, hazard ratio; IQR, interquartile range; NYHA, New York Heart Association.

Sacubitril/valsartan and loop diuretic requirement in heart failure with preserved ejection fraction in the PARAGON-HF trial.

EMPEROR-Reduced: effect of empagliflozin on heart failure outcomes, kidney function decline and weight according to body mass index categories. BMI, body mass index; CI, confidence interval; eGFR, estimated glomerular filtration rate; HFrEF, heart failure with reduced ejection fraction; HHF, hospitalization for heart failure; HR, hazard ratio; Wk, week.