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Front Cover

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Front Cover: ExSTA: External Standard Addition Method for Accurate High-Throughput Quantitation in Targeted Proteomics Experiments

Yassene Mohammed,  Jingxi Pan,  Suping Zhang,  Jun Han,  Christoph H. Borchers, 
  • First Published: 09 March 2018
Front Cover: ExSTA: External Standard Addition Method for Accurate High-Throughput Quantitation in Targeted Proteomics Experiments Volume 12 Issue 2, 2018

An MRM assay for high-to-moderate abundance human plasma proteins is used to compare classical quantitation approaches with the external NAT-addition method (ExSTA), which uses buffer and labeled and unlabeled internal standards of the surrogate peptides. This artistic interpretation shows how dilution series and replicate measurements in buffer produce the standard curve that is used to determine the target protein concentration in real samples. This is reported by Yassene Mohammed, Jingxi Pan, Suping Zhang, Jun Han, and Christoph H. Borchers in article number 1600180.

Editorial Board

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Editorial board: Proteomics 2'18

  • First Published: 09 March 2018

Masthead

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Masthead: Proteomics 2'18

  • First Published: 09 March 2018

Editorial

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The Special Issue: Clinical Proteomics for Precision Medicine

Carol E. Parker,  Christoph H. Borchers, 
  • First Published: 09 March 2018

Viewpoint

Rare Genetic Disorders

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Intersection of Proteomics and Genomics to “Solve the Unsolved” in Rare Disorders such as Neurodegenerative and Neuromuscular Diseases

Andreas Roos,  Rachel Thompson,  Rita Horvath,  Hanns Lochmüller,  Albert Sickmann, 
  • First Published: 23 October 2017

Reviews

Human Hair Proteomics

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Emerging Diagnostic and Therapeutic Potentials of Human Hair Proteomics

Henry A. Adeola,  Jennifer C. Van Wyk,  Afolake Arowolo,  Reginald M. Ngwanya,  Khwezikazi Mkentane,  Nonhlanhla P. Khumalo, 
  • First Published: 27 September 2017
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Mass spectrometry-based protein analysis to unravel the tissue pathophysiology in Duchenne muscular dystrophy

Stephanie J. Carr,  René P. Zahedi,  Hanns Lochmüller,  Andreas Roos, 
  • First Published: 20 June 2017

Personalized Medicine

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Clinical Proteomics for Precision Medicine: The Bladder Cancer Case

Agnieszka Latosinska,  Maria Frantzi,  Antonia Vlahou,  Axel S. Merseburger,  Harald Mischak, 
  • First Published: 05 October 2017

Research Articles

Protein Quantitation

Open Access

ExSTA: External Standard Addition Method for Accurate High-Throughput Quantitation in Targeted Proteomics Experiments

Yassene Mohammed,  Jingxi Pan,  Suping Zhang,  Jun Han,  Christoph H. Borchers, 
  • First Published: 11 September 2017

Comparative Proteome Analysis

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Using Public Data for Comparative Proteome Analysis in Precision Medicine Programs

Christopher S. Hughes,  Gregg B. Morin, 
  • First Published: 09 September 2017

Salivary Biomarkers

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Variability Assessment of 90 Salivary Proteins in Intraday and Interday Samples from Healthy Donors by Multiple Reaction Monitoring-Mass Spectrometry

Yung-Chin Hsiao,  Lichieh Julie Chu,  Yi-Ting Chen,  Lang-Ming Chi,  Kun-Yi Chien,  Wei-Fan Chiang,  Ya-Ting Chang,  Szu-Fan Chen,  Wei-Shun Wang,  Yao-Ning Chuang,  Shih-Yu Lin,  Chih-Yen Chien,  Kai-Ping Chang,  Yu-Sun Chang,  Jau-Song Yu, 
  • First Published: 19 January 2018

Non-Small-Cell Lung Cancer

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Chemotherapy Immunophenoprofiles in Non-Small-Cell Lung Cancer by Personalized Membrane Proteomics

Denise Utami Putri,  Po-Hao Feng,  Yuu-Hueih Hsu,  Kang-Yun Lee,  Feng-Wen Jiang,  Lu-Wei Kuo,  Yu-Ju Chen,  Chia-Li Han, 
  • First Published: 26 December 2017

Cytokeratin Markers

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An MRM-Based Cytokeratin Marker Assay as a Tool for Cancer Studies: Application to Lung Cancer Pleural Effusions

Anna Perzanowska,  Agnieszka Fatalska,  Grzegorz Wojtas,  Andrzej Lewandowicz,  Agata Michalak,  Grzegorz Krasowski,  Christoph H. Borchers,  Michal Dadlez,  Dominik Domanski, 
  • First Published: 19 January 2018

Erratum

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Multi-Pronged Proteomic Analysis to Study the Glioma Pathobiology using Cerebrospinal Fluid Samples

Nikita Gahoi,  Darpan Malhotra,  Aliasgar Moiyadi,  Santosh G. Varma,  Mayuri N. Gandhi,  Sanjeeva Srivastava, 
  • First Published: 09 March 2018