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    Annals of Neurology: Volume 93, Issue 1

    C1, i-vi, 1-212
    January 2023
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Free Access

Annals of Neurology: Volume 93, Number 1, January 2023

  • Page: C1
  • First Published: 10 January 2023

Issue Information

Free Access

Issue Information

  • Pages: i-vi
  • First Published: 10 January 2023

Editorial

Annual Report from the Editor-in-Chief (2022)

Kenneth L. Tyler, 
  • Pages: 1-12
  • First Published: 27 December 2022

In Memoriam

In Memoriam: Arthur Knight Asbury, MD (1928–2022)

Mark J. Brown MD,  Frances E. Jensen MD, FANA,  Howard Hurtig MD, 
  • Pages: 13-14
  • First Published: 16 November 2022

ANA Podcasts & Webinars

ANA Podcasts & Webinars: Genetics of Epilepsy

Rohit R. Das MD,  Adeline L. Goss MD,  Ingrid E. Scheffer AO, MBBS, PhD, 
  • Page: 15
  • First Published: 13 November 2022

Research Articles

Open Access

A Causal Classification System for Intracerebral Hemorrhage Subtypes

Nicolas Raposo MD, PhD,  Maria Clara Zanon Zotin MD,  David J. Seiffge MD,  Qi Li MD, PhD,  Martina B. Goeldlin MD,  Andreas Charidimou MD, PhD,  Ashkan Shoamanesh MD,  Hans Rolf Jäger MD, FRCP,  Charlotte Cordonnier MD, PhD,  Catharina JM Klijn MD, PhD,  Eric E. Smith MD, MPH,  Steven M. Greenberg MD, PhD,  David J. Werring MD, PhD,  Anand Viswanathan MD, PhD, 
  • Pages: 16-28
  • First Published: 05 October 2022
Open Access

CADASIL Affects Multiple Aspects of Cerebral Small Vessel Function on 7T-MRI

Hilde van den Brink MSc,  Anna Kopczak MD,  Tine Arts PhD,  Laurien Onkenhout MD,  Jeroen C.W. Siero PhD,  Jaco J.M. Zwanenburg PhD,  Sandra Hein BSc,  Mathias Hübner MSc,  Benno Gesierich PhD,  Marco Duering MD,  Michael S. Stringer PhD,  Jeroen Hendrikse MD, PhD,  Joanna M. Wardlaw MD,  Anne Joutel MD, PhD,  Martin Dichgans MD,  Geert Jan Biessels MD, PhD, on behalf of the SVDs@target group , 
  • Pages: 29-39
  • First Published: 12 October 2022
Open Access

Predicting Functional Outcome Using 24-Hour Post-Treatment Characteristics: Application of Machine Learning Algorithms in the STRATIS Registry

Alicia C. Castonguay PhD,  Zeinab Zoghi MS,  Osama O. Zaidat MD, MS,  Richard E. Burgess MD, PhD,  Syed F. Zaidi MD,  Nils Mueller-Kronast MD,  David S. Liebeskind MD,  Mouhammad A. Jumaa MD, 
  • Pages: 40-49
  • First Published: 10 October 2022
Open Access

Effect of Mobile Stroke Unit Dispatch in all Patients with Acute Stroke or TIA

Jessica L. Rohmann MScPH,  Marco Piccininni PhD,  Martin Ebinger MD,  Matthias Wendt MD,  Joachim E. Weber MD,  Eugen Schwabauer MD,  Frederik Geisler MD,  Erik Freitag MD,  Peter Harmel MD,  Irina Lorenz-Meyer MSc,  Ira Rohrpasser-Napierkowski Dr rer. nat.,  Christian H. Nolte MD,  Darius G. Nabavi MD,  Ingo Schmehl MD,  Axel Ekkernkamp MD,  Matthias Endres MD,  Heinrich J. Audebert MD, 
  • Pages: 50-63
  • First Published: 30 October 2022

Infratentorial Superficial Siderosis and Spontaneous Intracranial Hypotension

Wouter I. Schievink MD,  M. Marcel Maya MD,  Jennifer Harris MD,  Javier Galvan MD,  Rachelle B. Taché NP-C, MSN,  Miriam Nuño PhD, 
  • Pages: 64-75
  • First Published: 06 October 2022

Trans-Synaptic Degeneration Following Acute Optic Neuritis in Multiple Sclerosis

Olwen C. Murphy MBBCh,  Elias S. Sotirchos MD,  Grigorios Kalaitzidis MD,  Elena Vasileiou MD,  Henrik Ehrhardt MBBCh,  Jeffrey Lambe MBBCh,  Ohemaa Kwakyi BS,  James Nguyen MD,  Alexandra Zambriczki Lee BS,  Julia Button MD,  Blake E. Dewey PhD,  Scott D. Newsome DO,  Ellen M. Mowry MD,  Kathryn C. Fitzgerald ScD,  Jerry L. Prince PhD,  Peter A. Calabresi MD,  Shiv Saidha MBBCh, 
  • Pages: 76-87
  • First Published: 11 October 2022
Open Access

Fewer COVID-19 Neurological Complications with Dexamethasone and Remdesivir

Alexander Grundmann BMBCh,  Chieh-Hsi Wu PhD,  Marc Hardwick BMBCh,  J. Kenneth Baillie FRCA, PhD,  Peter J M Openshaw FRCP, PhD,  Malcolm G. Semple FRCPCH, PhD,  Dankmar Böhning PhD,  Sarah Pett FRACP, PhD,  Benedict D. Michael FRCP, PhD,  Rhys H. Thomas FRCP, PhD,  Ian Galea FRCP, PhD,  for the ISARIC4C investigators , 
  • Pages: 88-102
  • First Published: 19 October 2022

Brief Communication

Open Access

Ocrelizumab Concentration Is a Good Predictor of SARS-CoV-2 Vaccination Response in Patients with Multiple Sclerosis

Zoé L. E. van Kempen,  Laura Hogenboom,  Alyssa A. Toorop,  Maurice Steenhuis,  Eileen W. Stalman,  Laura Y. L. Kummer,  Koos P. J. van Dam,  Karien Bloem,  Anja ten Brinke,  S. Marieke van Ham,  Taco W. Kuijpers,  Gerrit J. Wolbink,  Floris C. Loeff,  Luuk Wieske,  Filip Eftimov,  Theo Rispens,  Eva M. M. Strijbis,  Joep Killestein, on behalf of the T2B! immunity against SARS-CoV-2 study group , 
  • Pages: 103-108
  • First Published: 17 October 2022

Research Articles

Mimics of Pediatric Small Vessel Primary Angiitis of the Central Nervous System

Coral M. Stredny MD,  Melissa M. Blessing DO,  Vivian Yi BS,  Morgan E. Ryan MS,  Bo Zhang PhD,  Isaac H. Solomon MD, PhD,  Sanjay P. Prabhu MBBS,  Sanda Alexandrescu MD,  Mark P. Gorman MD, 
  • Pages: 109-119
  • First Published: 17 October 2022

Exploring Gene Expression Profiles in Primary Central Nervous System Vasculitis

Carlo Salvarani MD,  Jonas Paludo MD,  Gene G. Hunder MD,  Stephen M. Ansell MD,  Caterina Giannini MD,  Joseph E. Parisi MD,  John Huston III MD,  Matthew J. Koster MD,  Kenneth J. Warrington MD,  Stefania Croci BS, PhD,  Robert D. Brown Jr MD, MPH, 
  • Pages: 120-130
  • First Published: 20 October 2022
Free Access

Functional Neuroimaging as an Assessment Tool in Critically Ill Patients

Loretta Norton PhD,  Karnig Kazazian BSc,  Teneille Gofton MD,  Derek B. Debicki MD, PhD,  Davinia Fernandez-Espejo PhD,  Jonathan E. Peelle PhD,  Eyad Al Thenayan MD,  G. Bryan Young MD,  Adrian M. Owen PhD, 
  • Pages: 131-141
  • First Published: 12 October 2022
Open Access

Synaptic Loss in Frontotemporal Dementia Revealed by [11C]UCB-J Positron Emission Tomography

Maura Malpetti PhD,  P. Simon Jones PhD,  Thomas E. Cope MD, PhD,  Negin Holland MD, PhD,  Michelle Naessens MSc,  Matthew A. Rouse MSc,  Timothy Rittman MD, PhD,  George Savulich PhD,  David J. Whiteside MD,  Duncan Street MD, PhD,  Tim D. Fryer PhD,  Young T. Hong PhD,  Selena Milicevic Sephton PhD,  Franklin I. Aigbirhio DPhil,  John T. O′Brien FRCPsych, DM,  James B. Rowe FRCP, PhD, 
  • Pages: 142-154
  • First Published: 02 November 2022

Brief Communication

CYFIP2 p.Arg87Cys Causes Neurological Defects and Degradation of CYFIP2

Muwon Kang BSc,  Yinhua Zhang PhD,  Hyae Rim Kang BSc,  Seoyeong Kim BSc,  Ruiying Ma BSc,  Yunho Yi,  Seungjoon Lee PhD,  Yoonhee Kim MSc,  Huiling Li BSc,  Chunmei Jin PhD,  Dongmin Lee MD, PhD,  Eunjoon Kim PhD,  Kihoon Han PhD, 
  • Pages: 155-163
  • First Published: 17 October 2022

Research Articles

Open Access

Magnetic Resonance Images Implicate That Glymphatic Alterations Mediate Cognitive Dysfunction in Alzheimer Disease

Jung-Lung Hsu MD, PhD,  Yi-Chia Wei MD, PhD,  Cheng Hong Toh MD, PhD,  Ing-Tsung Hsiao PhD,  Kun-Ju Lin MD, PhD,  Tzu-Chen Yen MD, PhD,  Ming-Feng Liao MD, PhD,  Long-Sun Ro MD, PhD, 
  • Pages: 164-174
  • First Published: 10 October 2022

Responses of Chemosensory Perception to Stimulation of the Human Brain

Yanyan Li PhD,  Zheng Tan PhD,  Jing Wang MBBS,  Yufei Cai BS,  Mengyang Wang MD,  Wen Zhou PhD,  Liang Wang PhD, 
  • Pages: 175-183
  • First Published: 11 October 2022

Neocortical Lewy Body Pathology Parallels Parkinson's Dementia, but Not Always

W. R. Wayne Martin MD,  John R. Younce MD,  Meghan C. Campbell PhD,  Brad A. Racette MD,  Scott A. Norris MD,  Mwiza Ushe MD,  Susan Criswell MD,  Albert A. Davis MD, PhD,  Isabel Alfradique-Dunham MD,  Baijayanta Maiti MD, PhD,  Nigel J. Cairns PhD,  Richard J. Perrin MD, PhD,  Paul T. Kotzbauer MD, PhD,  Joel S. Perlmutter MD, 
  • Pages: 184-195
  • First Published: 04 November 2022

Olfactory Neuron Prokineticin-2 as a Potential Target in Parkinson's Disease

Tommaso Schirinzi MD, PhD,  Daniela Maftei PhD,  Francesco M. Passali MD, PhD,  Piergiorgio Grillo MD,  Henri Zenuni MD,  Davide Mascioli MD,  Riccardo Maurizi MD,  Laura Loccisano MD,  Martina Vincenzi PhD,  Anna Maria Rinaldi,  Massimo Ralli MD, PhD,  Stefano Di Girolamo MD,  Alessandro Stefani MD, PhD,  Roberta Lattanzi PhD,  Cinzia Severini PhD,  Nicola B. Mercuri MD, PhD, 
  • Pages: 196-204
  • First Published: 11 October 2022

Brief Communication

Nocturnal Pulse Event Frequency Is Reduced in Multiple System Atrophy

Stuart J. McCarter MD,  Elizabeth A. Coon MD,  Eduardo E. Benarroch MD,  Michael H. Silber MB, ChB,  Erik K. St. Louis MD, MS, 
  • Pages: 205-212
  • First Published: 17 October 2022