Fragmented Intratumoral Thrombosed Microvasculature (FTV) in Glioblastoma IDHWT. The Figure Illustrates a Representative Slice from an Enhancing IDHWT GLIOMA Patient in the Analyzed Dataset, Featuring Pre-Surgery Flair, Post-Contrast T1-W, and SWI Images (A-C). (D) SWI Image, with Orange and Blue Arrow Pointing to FTV and Normal Vessels, Respectively. (E) A Zoomed-In View of the FTV and Normal Vessels. Tumor Subcomponents are Overlaid on the Post-Contrast T1-W Images (F), While the Intratumoral Susceptibility Signal (ITSS) Vasculature Mask Derived from SWI Images is Depicted in (G). (H) The ITSS Vasculature Alongside the Tumor Subcomponents Overlaid on the Post-Contrast T1-W Images, with (I) Presenting a Zoomed-In View of this Overlay. (J-L) The Corresponding rCBV, Ve, and Ktrans Images. The Orange and Blue Arrow on rCBV Map Shows the Low and High Values for the FTV and Normal Vessel, Respectively (M). (O) The Concentration Time Plot for Healthy (Blue Curve) Vessel and FTV (Orange Curve). (P-U) The Histopathology Images. H&E Section (2003) Showing a Highly Cellular Tumor with Palisading Necrosis (Arrow) (P). (Q) H&E Section (4003) In High Magnification Showing a Highly Cellular Glial Tumor. The Tumor Cells Show Moderate to Marked Pleomorphism. (R) H&E Section (1003) Showing Numerous Thrombosed Vessels (Arrow). (S) H&E Section (2003) In High Magnification Showing Thrombosed Vessel. (T) Strong Positivity for OLIG2 Immunohistochemistry. CD34 Highlights Endothelial Cells in Dilated and Thrombosed Vessels (U). Flair = Fluid-Attenuated Inversion Recovery; T1-W = T1-Weighted; SWI = Susceptibility-Weighted Imaging; rCBV = Relative Cerebral Blood Volume, KTRANS = Volume Transfer Coefficient; Ve = Fraction of Extravascular and Extracellular Space Volume). By Yadav et al. (258-270)