Volume 12, Issue 9 pp. 645-648
EDITOR'S RECOMMENDATION

Economic benefit of prescribing an adjusted renal dose of dipeptidyl peptidase IV inhibitors in type 2 diabetes patients with chronic kidney disease

调整二肽基肽酶IV抑制剂的剂量在2型糖尿病合并慢性肾病患者中的经济效益

Sun Joon Moon

Sun Joon Moon

Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea

Division of Endocrinology and Metabolism, Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea

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Young Min Cho

Corresponding Author

Young Min Cho

Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea

Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea

Correspondence

Young Min Cho, Department of Internal Medicine, Seoul National University College of Medicine, 101 Daehak-ro, Jongno-gu, Seoul 03080, Republic of Korea.

Email: [email protected]

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First published: 20 May 2020

摘要

主要内容

二肽基肽酶IV抑制剂(DPP-IVi)可用于2型糖尿病合并慢性肾脏病(T2D CKD)患者的治疗, 可以根据药物药代动力学特性调整或不调整剂量。鉴于DPP-IVi是一大类药物, 在T2D CKD患者中恰当使用需根据肾功能调整用量的DPP-IVi(RDA DPP-IVi), 而不是使用NRDA DPP-IVi, 将可以节约相当大的成本。

虽然一些研究揭示了T2D CKD患者DPP-IVi的处方模式, 但这些研究没有从经济影响的角度进行分析, 也没有使用具有全国代表性的数据。作者利用国家数据进行了一项真实的观察性研究, 以评估T2D CKD患者的DPP-IVi的处方模式, 以分析RDA DPP-IVi代替NRDA DPP-IVi的处方的经济影响。

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