Journal of Food Processing and Preservation

Volume 45, Issue 11 e15971

ORIGINAL ARTICLE

In vitro antimicrobial, antiradical, anticancer evaluation, and phytochemical contents of endemic Scorzonera semicana DC

Serhat Keser,

Corresponding Author

Serhat Keser

[email protected]

orcid.org/0000-0002-9678-1053

EOSB Higher Vocational School, Department of Chemical Technology, Firat University, Elazig, Turkey

Correspondence

Serhat Keser, EOSB Higher Vocational School, Department of Chemical Technology, Firat University, 23119 Elazig, Turkey.

Email: [email protected]

Contribution: Formal analysis, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing - original draft, Writing - review & editing

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Oguzhan Kak,

Oguzhan Kak

Faculty of Science, Department of Chemistry, Firat University, Elazig, Turkey

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Serhat Keser,

Corresponding Author

Serhat Keser

[email protected]

orcid.org/0000-0002-9678-1053

EOSB Higher Vocational School, Department of Chemical Technology, Firat University, Elazig, Turkey

Correspondence

Serhat Keser, EOSB Higher Vocational School, Department of Chemical Technology, Firat University, 23119 Elazig, Turkey.

Email: [email protected]

Contribution: Formal analysis, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing - original draft, Writing - review & editing

Search for more papers by this author

Oguzhan Kak,

Oguzhan Kak

Faculty of Science, Department of Chemistry, Firat University, Elazig, Turkey

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First published: 20 September 2021

https://doi.org/10.1111/jfpp.15971

Citations: 12

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Abstract

In the present study, antimicrobial, antiradical, and anticancer properties with phytochemical compounds of endemic Scorzonera semicana DC., which grown in Elazig (from Turkey) around and consumed as a vegetable, were investigated. The antiradical properties of extracts were determined via DPPH, ABTS, OH radical scavenging activities, and their antimicrobial properties were determined against several microorganisms. Anticancer properties of this plant were determined by MTT assay on the HCT-116, LNCaP, and MCF-7 under in vitro conditions. It was determined that S. semicana water (94.81%) and methanol (98.87%) extracts for scavenging of ABTS (BHT, 93.24%); water, ethanol, and methanol extracts (84.97%, 84.29%, and 84.62%, respectively) for scavenging of OH radicals showed higher activity than BHT (75.77%). It was observed that flavonoid (5,555.34 µg CE/g), proanthocyanidin (1,860.78 µg CE/g), and phenolic (134.89 mg GAE/g) contents were found to be highest in S. semicana methanol extract. All extracts had higher antimicrobial activity than standard antibiotics against Listeria monocytogenes. This plant showed very effective anticancer activity increasing dose-dependently on LNCaP, MCF-7, and HCT-116 cancer cell lines.

Practical applications

In Turkey, Scorzonera semicana DC. is cultivated and consumed as vegetables, and the roots, fresh shoots of this species are consumed by the name of “yemlik” as feed or fresh in Anatolia. This study investigated its antiradical, antimicrobial, anticancer, phytochemical properties and is first report about in vitro biological properties of S. semicana. According to our results, S. semicana most effective for ABTS and OH radical scavenging activity and show very effective anticancer activity on LNCaP, MCF-7, HCT-116 cells.

CONFLICTS OF INTEREST

The author declares that there is no conflict of interest that could be perceived as prejudicing the impartiality of the research reported.

Open Research

DATA AVAILABILITY STATEMENT

The data that support the findings of this study are available from the corresponding author upon reasonable request.

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In vitro antimicrobial, antiradical, anticancer evaluation, and phytochemical contents of endemic Scorzonera semicana DC

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In vitro antimicrobial, antiradical, anticancer evaluation, and phytochemical contents of endemic Scorzonera semicana DC

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Practical applications

CONFLICTS OF INTEREST

Open Research

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