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Research Article
Open Access

oa

Matrix metalloproteinase-1 facilitates MSC migration via cleavage of IGF-2/IGFBP2 complex

Shou P. Guan, Alan T.L. Lam, Jennifer P. Newman, Kevin L.M. Chua, Catherine Y.L. Kok, Siao T. Chong, Melvin L.K. Chua, Paula Y.P. Lam,

FEBS Open Bio Volume 8, Issue 1
First published: 06 October 2017
Collections: Cancer Biology: Highlights from 2018—2020

Abstract
Full Paper
Open Access

oa

Germline Polymorphisms and Length of Survival of Nasopharyngeal Carcinoma: An Exome-Wide Association Study in Multiple Cohorts

Yun-Miao Guo, Jie-Rong Chen, Yan-Chun Feng, Melvin L. K. Chua, Yanni Zeng, Edwin Pun Hui, Allen K. C. Chan, Lin-Quan Tang, Lin Wang, Qian Cui, Hui-Qiong Han, Chun-Ling Luo, Guo-Wang Lin, Yan Liang, Yang Liu, Zhong-Lian He, Yu-Xiang Liu, Pan-Pan Wei, Chu-Jun Liu, Wan Peng, Bo-Wei Han, Xiao-Yu Zuo, Enya H. W. Ong, Eugenia L. L. Yeo, Kar Perng Low, Gek San Tan, Tony K. H. Lim, Jacqueline S. G. Hwang, Bo Li, Qi-Sheng Feng, Xiaojun Xia, Yun-Fei Xia, Josephine Ko, Wei Dai, Maria L. Lung, Anthony T. C. Chan, Dennis Y. M. Lo, Mu-Sheng Zeng, Hai-Qiang Mai, Jianjun Liu, Yi-Xin Zeng, Jin-Xin Bei,

Advanced Science Volume 7, Issue 10
First published: 20 March 2020

Abstract
RESEARCH HIGHLIGHT
Open Access

oa

Surgery as an alternative to radiotherapy in early-stage nasopharyngeal carcinoma: innovation at the expense of uncertainty

Luo Huang, Melvin L.K. Chua,

Cancer Communications Volume 40, Issue 2-3
First published: 18 March 2020
Collections: NPC Head and Neck Cancer
LETTER TO THE EDITOR
Open Access

oa

Clinical outcomes of coronavirus disease 2019 (COVID-19) in cancer patients with prior exposure to immune checkpoint inhibitors

Qiuji Wu, Qian Chu, Hongyan Zhang, Bin Yang, Xudong He, Yahua Zhong, Xianglin Yuan, Melvin L.K. Chua, Conghua Xie,

Cancer Communications Volume 40, Issue 8
First published: 15 July 2020
Collections: Cellular and molecular biology
LETTER TO THE EDITOR
Open Access

oa

Transcriptomic analyses of localized prostate cancers of East Asian and North American men reveal race-specific luminal-basal and microenvironmental differences

Melvin L. K. Chua, Alexander K. Hakansson, Enya H. W. Ong, Boon Hao Hong, Jing Jing Miao, Adelene Y. L. Sim, Janice S. H. Tan, Kah Min Tan, Gabrielle C. J. Lee, Kar Perng Low, Jeffrey K. L. Tuan, Terence W. K. Tan, Michael L. C. Wang, Joe P. S. Yeong, Michael C. S. Tan, Lui Shiong Lee, Ravindran Kanesvaran, Xin Zhao, Julian Ho, Daniel E. Spratt, Edward M. Schaeffer, Kae-Jack Tay, Yang Liu, Elai Davicioni, Li Yan Khor,

Cancer Communications Volume 43, Issue 10
First published: 12 September 2023
Original Article
Open Access

oa

Outcomes of novel coronavirus disease 2019 (COVID-19) infection in 107 patients with cancer from Wuhan, China

Hongyan Zhang MD, Linwei Wang MD, Yuanyuan Chen MD, Qiuji Wu MD, PhD, Gaili Chen MD, PhD, Xiaokun Shen PhD, Qun Wang MD, Youqin Yan MD, Yi Yu MD, Yahua Zhong MD, PhD, Xinghuan Wang MD, PhD, Melvin L. K. Chua MBBS, FRCR, PhD, Conghua Xie MD, PhD,

Cancer Volume 126, Issue 17
First published: 23 June 2020
Collections: COVID-19 and Oncology Special Collection

Abstract
Correspondence
Free Access

free

Reply to Colorectal cancer and COVID-19: Do we need to raise awareness and vigilance?

Qiuji Wu MD, PhD, Hongyan Zhang MD, Yahua Zhong MD, PhD, Melvin L. K. Chua MBBS, FRCR, PhD, Conghua Xie MD, PhD,

Cancer Volume 127, Issue 6
First published: 26 January 2021
Tumor Immunology and Microenvironment

no

Immune checkpoint inhibitors in advanced nasopharyngeal carcinoma: Beyond an era of chemoradiation?

Liam Masterson, James Howard, Jazmina Gonzalez-Cruz, Christopher Jackson, Catherine Barnett, Lewis Overton, Howard Liu, Rahul Ladwa, Fiona Simpson, Margie McGrath, Ben Wallwork, Terry Jones, Christian Ottensmeier, Melvin L.K. Chua, Chris Perry, Rajiv Khanna, Benedict Panizza, Sandro Porceddu, Matt Lechner,

International Journal of Cancer Volume 146, Issue 8
First published: 17 January 2020

Abstract
Original Article
Open Access

oa

Effects of induction chemotherapy on nutrition status in locally advanced nasopharyngeal carcinoma: a multicentre prospective study

Jingjing Miao, Lin Wang, Enya H.W. Ong, Chaosu Hu, Shaojun Lin, Xiaozhong Chen, Yuanyuan Chen, Yahua Zhong, Feng Jin, Qin Lin, Shaomin Lin, Xuefeng Hu, Ning Zhang, Rensheng Wang, Cong Wang, Xiang Guo, Nelson L.F. Yit, Hanping Shi, Sze Huey Tan, Haiqiang Mai, Conghua Xie, Melvin L.K. Chua, Chong Zhao,

Journal of Cachexia, Sarcopenia and Muscle Volume 14, Issue 2
First published: 05 March 2023

Abstract
RESEARCH ARTICLE
Full Access

full

Nonpharmaceutical interventions reduce the incidence and mortality of COVID-19: A study based on the survey from the International COVID-19 Research Network (ICRN)

Seung Hyun Park, Sung Hwi Hong, Kwanghyun Kim, Seung Won Lee, Dong Keon Yon, Sun Jae Jung, Ziad Abdeen, Ramy Abou Ghayda, Mohamed Lemine Cheikh Brahim Ahmed, Abdulwahed Al Serouri, Waleed Al-Herz, Humaid O. Al-Shamsi, Sheeza Ali, Kosar Ali, Oidov Baatarkhuu, Henning Bay Nielsen, Enrico Bernini-Carri, Anastasiia Bondarenko, Ayun Cassell, Akway Cham, Melvin L. K. Chua, Sufia Dadabhai, Tchin Darre, Hayk Davtyan, Elena Dragioti, Barbora East, Robert Jeffrey Edwards, Martina Ferioli, Tsvetoslav Georgiev, Lilian A. Ghandour, Harapan Harapan, Po-Ren Hsueh, Saad I. Mallah, Aamer Ikram, Shigeru Inoue, Louis Jacob, Slobodan M. Janković, Umesh Jayarajah, Milos Jesenak, Pramath Kakodkar, Nathan Kapata, Yohannes Kebede, Yousef Khader, Meron Kifle, David Koh, Višnja Kokić Maleš, Katarzyna Kotfis, Ai Koyanagi, James-Paul Kretchy, Sulaiman Lakoh, Jinhee Lee, Jun Young Lee, Maria da Luz Lima Mendonça, Lowell Ling, Jorge Llibre-Guerra, Masaki Machida, Richard Makurumidze, Ziad A. Memish, Ivan Mendoza, Sergey Moiseev, Thomas Nadasdy, Chen Nahshon, Silvio A. Ñamendys-Silva, Blaise Nguendo Yongsi, Amalea Dulcene Nicolasora, Zhamilya Nugmanova, Hans Oh, Atte Oksanen, Oluwatomi Owopetu, Zeynep Ozge Ozguler, Konstantinos Parperis, Gonzalo Emanuel Perez, Krit Pongpirul, Marius Rademaker, Nemanja Radojevic, Anna Roca, Alfonso J. Rodriguez-Morales, Enver Roshi, Khwaja Mir Islam Saeed, Ranjit Sah, Boris Sakakushev, Dina E. Sallam, Brijesh Sathian, Patrick Schober, P. Shaik Syed Ali, Zoran Simonović, Tanu Singhal, Natia Skhvitaridze, Marco Solmi, Kannan Subbaram, Kalthoum Tizaoui, John Thato Tlhakanelo, Julio Torales, Junior Smith Torres-Roman, Dimitrios Tsartsalis, Jadamba Tsolmon, Duarte Nuno Vieira, Sandro G. Viveiros Rosa, Guy Wanghi, Uwe Wollina, Ren-He Xu, Lin Yang, Kashif Zia, Muharem Zildzic, Jae Il Shin, Lee Smith,

Journal of Medical Virology Volume 95, Issue 2
First published: 29 November 2022

Abstract
HEAD AND NECK, AND TUMOR BIOLOGY
Open Access

oa

Electronic tumor board presentations as the basis for the development of a head and neck cancer database

Mahalakshmi Rangabashyam MBBS, MRCSEd( ENT), DipNB (ENT), Hide E. Wee MBBS, MRCS, MBA, Weining Wang MD, Stefan Mueller MBBS, MRCSEd (ENT), Khairul A. B. A. Karim BSc, Thakshayeni Skanthakumar BSc, Bhuvaneshwari Hariraman BDS, Dip.CTM (clinical Trials Management), Kiattisa Sommat MBBS, FRCR, Yoke-Lim Soong MBBS, FRCR, FFRRCSI, Melvin L. K. Chua MBBS, FRCR, PhD, Gerald Tay MBBS, MMed, FRCSEd, Ngian -Chye Tan MBBS, MMed, FRCSEd, FAMS, Hiang Khoon- Tan MBBS, PhD, FRCSEd, FAMS, N. Gopalakrishna Iyer MBBS, PhD, FRCSEd, FAMS,

Laryngoscope Investigative Otolaryngology Volume 5, Issue 1
First published: 19 January 2020

Abstract
ORIGINAL ARTICLE
Open Access

oa

Patient-reported functional outcomes and oncological control after primary focal cryotherapy for clinically significant prostate cancer: A Phase II mandatory biopsy-monitored study

Yu G. Tan MBBS, MRCS, MCI, Yan M. Law MBBS, FRCR, Nye T. Ngo MBBS, MRCP, FRCPath, Li Y. Khor MBBCh, American Board of Pathology, Puay H. Tan MBBS, FRCPath, Enya H. W. Ong BSc, John S. P. Yuen MBBS, FRCS, FAMS, DPhil, Henry S. S. Ho MBBS, FRCS, FAMS, Jeffrey K. L. Tuan MBBS, MSc, FRCR, FAMS, Ravindran Kanesvaran MD, MRCP, FAMS, Rajan T. Gupta MD, American Board of Radiology, Steven Rozen BA, MS, PHD, Melvin L. K. Chua MBBS, FRCR, PhD, FAMS, Thomas J. Polascik MD, FACS, Kae Jack Tay MBBS, MRCS, MCI, FAMS,

The Prostate Volume 83, Issue 8
First published: 09 March 2023

Abstract
ORIGINAL ARTICLE
Open Access

oa

Managing advanced prostate cancer in the Asia Pacific region: “Real-world” application of Advanced Prostate Cancer Consensus Conference 2019 statements

Edmund Chiong, Declan G. Murphy, Nicholas C. Buchan, Melvin L. K. Chua, Lukman Hakim, Agus Rizal Hamid, Sung K. Hong, Lisa G. Horvath, Ravi Kanesvaran, Makarand Khochikar, Jason Letran, Bannakij Lojanapiwat, Rohan Malek, Anthony C. F. Ng, Nguyễn Tuấn Vinh, See-Tong Pang, Darren M. C. Poon, Teng Aik Ong, Marniza Saad, Kathryn Schubach, Ryoichi Shiroki, Levent Türkeri, Scott Williams, Alvin Wong, Dingwei Ye, ANZUP Cancer Trials Group, Ian D. Davis,

Asia-Pacific Journal of Clinical Oncology Volume 18, Issue 6
First published: 08 February 2022

Abstract
ORIGINAL ARTICLE
Open Access

oa

Efficacy, toxicity, and quality-of-life outcomes of ultrahypofractionated radiotherapy in patients with localized prostate cancer: A single-arm phase 2 trial from Asia

Janice S. H. Tan, Jonathan Y. H. Teh, Laura L. Y. Tan, Sheena X. F. Tan, You Quan Li, Terence W. K. Tan, Michael L. C. Wang, Ravindran Kanesvaran, Enya H. W. Ong, Kae Jack Tay, Lui Shiong Lee, Jeffrey K. L. Tuan, Daniel Y. H. Tan, Melvin L. K. Chua,

Asia-Pacific Journal of Clinical Oncology Volume 18, Issue 5
First published: 14 December 2021

Abstract
ORIGINAL ARTICLE
Open Access

oa

Management of advanced prostate cancer in the Asia-Pacific region: Summary of the Asia-Pacific Advanced Prostate Cancer Consensus Conference 2023

Edmund Chiong, Declan G. Murphy, Nicholas Buchan, Kenneth Chen, Sarah S. Chen, Melvin L. K. Chua, Agus Rizal Hamid, Ravindran Kanesvaran, Makarand Khochikar, Jason Letran, Bannakij Lojanapiwat, Indranil Mallik, Chee Fai Ng, Teng Aik Ong, Darren M. C. Poon, Yeong-Shiau Pu, Marniza Saad, Kathryn Schubach, Kiyoshi Takahara, Jeremy Tey, Sue-Ping Thang, Poh Choo Toh, Levent Türkeri, Nguyễn Tuấn Vinh, Scott Williams, Dingwei Ye, ANZUP Cancer Trials Group, Ian D. Davis,

Asia-Pacific Journal of Clinical Oncology Volume 20, Issue 4
First published: 16 April 2024

Abstract
Review

no

Selective treatment de-escalation in advanced prostate cancer: have we come full circle?

Bryan Chong, Marniza Saad, Tsung Wen Chong, John Thng, Yu Guang Tan, Kae Jack Tay, Christopher Cheng, Po-Hung Lin, Jeremy Teoh, Peter Ka-Fung Chiu, Nathan Lawrentschuk, Renu Eapen, Declan Murphy, Johan Chan, Melvin L.K. Chua, Jeffrey Tuan, John Yuen, Ravindran Kanesvaran, Kenneth Chen,

BJU International Volume 135, Issue 5
First published: 02 January 2025

Abstract
Research Highlight
Open Access

oa

Optimal sequencing of chemotherapy with chemoradiotherapy based on TNM stage classification and EBV DNA in locoregionally advanced nasopharyngeal carcinoma

Li-Ting Liu, Melvin L. K. Chua, Yungan Tao, Lin-Quan Tang, Hai-Qiang Mai,

Cancer Communications Volume 39, Issue 1
First published: 25 October 2019
Collections: NPC Head and Neck Cancer
Global Health and Cancer
Open Access

oa

A Practical Approach to the Management of Cancer Patients During the Novel Coronavirus Disease 2019 (COVID-19) Pandemic: An International Collaborative Group

Humaid O. Al-Shamsi, Waleed Alhazzani, Ahmad Alhuraiji, Eric A. Coomes, Roy F. Chemaly, Meshari Almuhanna, Robert A. Wolff, Nuhad K. Ibrahim, Melvin L.K. Chua, Sebastien J. Hotte, Brandon M. Meyers, Tarek Elfiki, Giuseppe Curigliano, Cathy Eng, Axel Grothey, Conghua Xie,

The Oncologist Volume 25, Issue 6
First published: 03 April 2020
Collections: Sharing Knowledge: An Anniversary Retrospective COVID-19 and Cancer Article Collection

Abstract
Letters to the Editor
Free Access

free

In Reply

Eric A. Coomes, Humaid O. Al-Shamsi, Brandon M. Meyers, Waleed Alhazzani, Ahmad Alhuraiji, Roy F. Chemaly, Meshari Almuhanna, Robert A. Wolff, Nuhad K. Ibrahim, Melvin L.K. Chua, Sebastien J. Hotte, Tarek Elfiki, Giuseppe Curigliano, Cathy Eng, Axel Grothey, Conghua Xie,

The Oncologist Volume 25, Issue 8
First published: 07 May 2020
Collections: COVID-19 and Cancer Article Collection
Letters to the Editor
Free Access

free

Evolution of Cancer Care in Response to the COVID-19 Pandemic

Eric A. Coomes, Humaid O. Al-Shamsi, Brandon M. Meyers, Waleed Alhazzani, Ahmad Alhuraiji, Roy F. Chemaly, Meshari Almuhanna, Robert A. Wolff, Nuhad K. Ibrahim, Melvin L.K. Chua, Sebastien J. Hotte, Tarek Elfiki, Giuseppe Curigliano, Cathy Eng, Axel Grothey, Conghua Xie,

The Oncologist Volume 25, Issue 9
First published: 14 June 2020
Collections: COVID-19 and Cancer Article Collection

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oa Matrix metalloproteinase-1 facilitates MSC migration via cleavage of IGF-2/IGFBP2 complex

oa Germline Polymorphisms and Length of Survival of Nasopharyngeal Carcinoma: An Exome-Wide Association Study in Multiple Cohorts

oa Surgery as an alternative to radiotherapy in early-stage nasopharyngeal carcinoma: innovation at the expense of uncertainty

oa Clinical outcomes of coronavirus disease 2019 (COVID-19) in cancer patients with prior exposure to immune checkpoint inhibitors

oa Transcriptomic analyses of localized prostate cancers of East Asian and North American men reveal race-specific luminal-basal and microenvironmental differences

oa Outcomes of novel coronavirus disease 2019 (COVID-19) infection in 107 patients with cancer from Wuhan, China

free Reply to Colorectal cancer and COVID-19: Do we need to raise awareness and vigilance?

no Immune checkpoint inhibitors in advanced nasopharyngeal carcinoma: Beyond an era of chemoradiation?

oa Effects of induction chemotherapy on nutrition status in locally advanced nasopharyngeal carcinoma: a multicentre prospective study

full Nonpharmaceutical interventions reduce the incidence and mortality of COVID-19: A study based on the survey from the International COVID-19 Research Network (ICRN)

oa Electronic tumor board presentations as the basis for the development of a head and neck cancer database

oa Patient-reported functional outcomes and oncological control after primary focal cryotherapy for clinically significant prostate cancer: A Phase II mandatory biopsy-monitored study

oa Managing advanced prostate cancer in the Asia Pacific region: “Real-world” application of Advanced Prostate Cancer Consensus Conference 2019 statements

oa Efficacy, toxicity, and quality-of-life outcomes of ultrahypofractionated radiotherapy in patients with localized prostate cancer: A single-arm phase 2 trial from Asia

oa Management of advanced prostate cancer in the Asia-Pacific region: Summary of the Asia-Pacific Advanced Prostate Cancer Consensus Conference 2023

no Selective treatment de-escalation in advanced prostate cancer: have we come full circle?

oa Optimal sequencing of chemotherapy with chemoradiotherapy based on TNM stage classification and EBV DNA in locoregionally advanced nasopharyngeal carcinoma

oa A Practical Approach to the Management of Cancer Patients During the Novel Coronavirus Disease 2019 (COVID-19) Pandemic: An International Collaborative Group

free In Reply

free Evolution of Cancer Care in Response to the COVID-19 Pandemic

oa

Matrix metalloproteinase-1 facilitates MSC migration via cleavage of IGF-2/IGFBP2 complex

oa

Germline Polymorphisms and Length of Survival of Nasopharyngeal Carcinoma: An Exome-Wide Association Study in Multiple Cohorts

oa

Surgery as an alternative to radiotherapy in early-stage nasopharyngeal carcinoma: innovation at the expense of uncertainty

oa

Clinical outcomes of coronavirus disease 2019 (COVID-19) in cancer patients with prior exposure to immune checkpoint inhibitors

oa

Transcriptomic analyses of localized prostate cancers of East Asian and North American men reveal race-specific luminal-basal and microenvironmental differences

oa

Outcomes of novel coronavirus disease 2019 (COVID-19) infection in 107 patients with cancer from Wuhan, China

free

Reply to Colorectal cancer and COVID-19: Do we need to raise awareness and vigilance?

no

Immune checkpoint inhibitors in advanced nasopharyngeal carcinoma: Beyond an era of chemoradiation?

oa

Effects of induction chemotherapy on nutrition status in locally advanced nasopharyngeal carcinoma: a multicentre prospective study

full

Nonpharmaceutical interventions reduce the incidence and mortality of COVID-19: A study based on the survey from the International COVID-19 Research Network (ICRN)

oa

Electronic tumor board presentations as the basis for the development of a head and neck cancer database

oa

Patient-reported functional outcomes and oncological control after primary focal cryotherapy for clinically significant prostate cancer: A Phase II mandatory biopsy-monitored study

oa

Managing advanced prostate cancer in the Asia Pacific region: “Real-world” application of Advanced Prostate Cancer Consensus Conference 2019 statements

oa

Efficacy, toxicity, and quality-of-life outcomes of ultrahypofractionated radiotherapy in patients with localized prostate cancer: A single-arm phase 2 trial from Asia

oa

Management of advanced prostate cancer in the Asia-Pacific region: Summary of the Asia-Pacific Advanced Prostate Cancer Consensus Conference 2023

no

Selective treatment de-escalation in advanced prostate cancer: have we come full circle?

oa

Optimal sequencing of chemotherapy with chemoradiotherapy based on TNM stage classification and EBV DNA in locoregionally advanced nasopharyngeal carcinoma

oa

A Practical Approach to the Management of Cancer Patients During the Novel Coronavirus Disease 2019 (COVID-19) Pandemic: An International Collaborative Group

free

In Reply

free

Evolution of Cancer Care in Response to the COVID-19 Pandemic