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    2021
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Review Article
Open Access

Ginsenoside Rg1 as a Potential Regulator of Hematopoietic Stem/Progenitor Cells

Fang He,  Guanping Yao, 
  • First Published: 31 December 2021
Research Article
Open Access

CircRNA FAT1 Regulates Osteoblastic Differentiation of Periodontal Ligament Stem Cells via miR-4781-3p/SMAD5 Pathway

Yu Ye,  Yue Ke,  Liu Liu,  Tong Xiao,  Jinhua Yu, 
  • First Published: 29 December 2021
Research Article
Open Access

p57 Suppresses the Pluripotency and Proliferation of Mouse Embryonic Stem Cells by Positively Regulating p53 Activation

Na Li,  Zhaoyu Du,  Yunxiang Li,  Wenjing Xu,  Yumei Yang,  Haodong Peng,  Tianxiang Song,  Qihua Qin,  Huining Lei,  Jinlian Hua, 
  • First Published: 24 December 2021
Review Article
Open Access

Spidroin-Based Biomaterials in Tissue Engineering: General Approaches and Potential Stem Cell Therapies

Qi Zhang,  Min Li,  Wenbo Hu,  Xin Wang,  Jinlian Hu, 
  • First Published: 20 December 2021
Research Article
Open Access

Proteogenomic Analysis Reveals Proteins Involved in the First Step of Adipogenesis in Human Adipose-Derived Stem Cells

Bernardo Bonilauri,  Amanda C. Camillo-Andrade,  Marlon D. M. Santos,  Juliana de S. da G. Fischer,  Paulo C. Carvalho,  Bruno Dallagiovanna, 
  • First Published: 16 December 2021
Research Article
Open Access

MicroRNA Hsa-Let-7b Regulates the Osteogenic Differentiation of Human Periodontal Ligament Stem Cells by Targeting CTHRC1

Lin Fu,  Na Li,  Yu Ye,  Xiaying Ye,  Tong Xiao,  Xiao Wu,  Yanxia Ma,  Jinhua Yu, 
  • First Published: 14 December 2021
Research Article
Open Access

Evaluation for Retinal Therapy for RPE65 Variation Assessed in hiPSC Retinal Pigment Epithelial Cells

Benjamin M. Nash,  To Ha Loi,  Milan Fernando,  Amin Sabri,  James Robinson,  Anson Cheng,  Steven S. Eamegdool,  Elizabeth Farnsworth,  Bruce Bennetts,  John R. Grigg,  Seo-Kyung Chung,  Anai Gonzalez-Cordero,  Robyn V. Jamieson, 
  • First Published: 13 December 2021
Review Article
Open Access

Small Ruminant Models for Articular Cartilage Regeneration by Scaffold-Based Tissue Engineering

Liqing Peng,  Bin Zhang,  Xujiang Luo,  Bo Huang,  Jian Zhou,  Shuangpeng Jiang,  Weimin Guo,  Guangzhao Tian,  Zhuang Tian,  Shi Shen,  Yangyang Li,  Xiang Sui,  Shuyun Liu,  Quanyi Guo,  Haibo Li, 
  • First Published: 06 December 2021
Research Article
Open Access

Mechanical Stress-Induced IGF-1 Facilitates col-I and col-III Synthesis via the IGF-1R/AKT/mTORC1 Signaling Pathway

Bin Yan,  Canjun Zeng,  Yuhui Chen,  Minjun Huang,  Na Yao,  Jie Zhang,  Bo Yan,  Jiajun Tang,  Liang Wang,  Zhongmin Zhang, 
  • First Published: 06 December 2021
Research Article
Open Access

Extracellular Vesicles Released from Neprilysin Gene-Modified Human Umbilical Cord-Derived Mesenchymal Stem Cell Enhance Therapeutic Effects in an Alzheimer’s Disease Animal Model

HyeJu Jeong,  Ok Joon Kim,  Seung-Hun Oh,  Sanghoon Lee,  Han A. Reum Lee,  Kee Ook Lee,  Boo-Yong Lee,  Nam Keun Kim, 
  • First Published: 03 December 2021
Research Article
Open Access

EZH2 Might Affect Macrophage Chemotaxis and Anti-Inflammatory Factors by Regulating CCL2 in Dental Pulp Inflammation

Ziqi Hu,  Yingyi Chen,  Jie He,  He Liu,  Tianqian Hui, 
  • First Published: 01 December 2021
Research Article
Open Access

EZH2 Regulates Lipopolysaccharide-Induced Periodontal Ligament Stem Cell Proliferation and Osteogenesis through TLR4/MyD88/NF-κB Pathway

Pengcheng Wang,  Huan Tian,  Zheng Zhang,  Zuomin Wang, 
  • First Published: 01 December 2021
Review Article
Open Access

Cloning and Embryo Splitting in Mammalians: Brief History, Methods, and Achievements

Mohaddeseh Rahbaran,  Ehsan Razeghian,  Marwah Suliman Maashi,  Abduladheem Turki Jalil,  Gunawan Widjaja,  Lakshmi Thangavelu,  Mariya Yurievna Kuznetsova,  Pourya Nasirmoghadas,  Farid Heidari,  Faroogh Marofi,  Mostafa Jarahian, 
  • First Published: 30 November 2021

Review Article
Open Access

Gene Editing in Pluripotent Stem Cells and Their Derived Organoids

Hang Zhou,  Yun Wang,  Li-Ping Liu,  Yu-Mei Li,  Yun-Wen Zheng, 
  • First Published: 30 November 2021
Research Article
Open Access

Cytological Effects of Serum Isolated from Polytraumatized Patients on Human Bone Marrow-Derived Mesenchymal Stem Cells

Yazhou Long,  Katrin Bundkirchen,  Pascal Gräff,  Christian Krettek,  Sandra Noack,  Claudia Neunaber, 
  • First Published: 28 November 2021
Research Article
Open Access

Treatment of Radiation Bone Injury with Transplanted hUCB-MSCs via Wnt/β-Catenin

Yufeng Zhang,  Huaxin Deng,  Zhiqiang Yang,  Zhe Chen,  Sheng Zhang,  Yufan Zhu,  Min Yang,  Houcheng Zhong,  Fuling Zhou,  Yuanlong Xie,  Lin Cai, 
  • First Published: 28 November 2021
Research Article
Open Access

Melatonin Alleviates LPS-Induced Pyroptotic Cell Death in Human Stem Cell-Derived Cardiomyocytes by Activating Autophagy

Ya Qiu,  Yan Ma,  Min Jiang,  Sulei Li,  Jibin Zhang,  Haixu Chen,  Mengqi Xu,  Shan Gao,  Lei Tian,  Bo Tao,  Yabin Wang,  Dong Han,  Feng Cao, 
  • First Published: 27 November 2021
Research Article
Open Access

Dual Effects of Hypoxia-Inducible Factors-1 Alpha in Bleomycin-Induced Pulmonary Fibrosis Treated by Human Umbilical Cord Mesenchymal Stem Cells

Hongpeng Zhang,  Hao Wang,  Yong Xia,  Nianmin Qi, 
  • First Published: 26 November 2021
Research Article
Open Access

lncRNA TUG1 Facilitates Colorectal Cancer Stem Cell Characteristics and Chemoresistance by Enhancing GATA6 Protein Stability

Junfeng Sun,  Hangyuan Zhou,  Xingqi Bao,  Yue Wu,  Haowei Jia,  Hongchao Zhao,  Guanghui Liu, 
  • First Published: 23 November 2021
Research Article
Open Access

RAB37 Promotes Adipogenic Differentiation of hADSCs via the TIMP1/CD63/Integrin Signaling Pathway

Haili Huang,  Anran Li,  Jin Li,  Dan Sun,  Ling Liang,  Kunyan Pan,  Chengzhang He,  Peihua Zhang, 
  • First Published: 23 November 2021
Research Article
Open Access

Proliferin-1 Ameliorates Cardiotoxin-Related Skeletal Muscle Repair in Mice

Hiroki Goto,  Aiko Inoue,  Limei Piao,  Lina Hu,  Zhe Huang,  Xiangkun Meng,  Yusuke Suzuki,  Hiroyuki Umegaki,  Masafumi Kuzuya,  Xian Wu Cheng, 
  • First Published: 20 November 2021
Erratum
Open Access

Erratum to “Gli1+ Cells Residing in Bone Sutures Respond to Mechanical Force via IP3R to Mediate Osteogenesis”

Xiaoyao Huang,  Zihan Li,  Peisheng Liu,  Meiling Wu,  An-qi Liu,  Chenghu Hu,  Xuemei Liu,  Hao Guo,  Xiaoxue Yang,  Xiaohe Guo,  Bei Li,  Xiaoning He,  Kun Xuan,  Yan Jin, 
  • First Published: 20 November 2021

Research Article
Open Access

PTHG2 Reduces Bone Loss in Ovariectomized Mice by Directing Bone Marrow Mesenchymal Stem Cell Fate

Jiao Chen,  Hao Zhang,  Xianmin Wu,  Fuxiao Wang,  Yili Wang,  Qianmin Gao,  Han Liu,  Yan Hu,  Jiacan Su,  Yingying Jing, 
  • First Published: 19 November 2021
Research Article
Open Access

RIPK1 Coordinates Bone Marrow Mesenchymal Stem Cell Survival by Maintaining Mitochondrial Homeostasis via p53

Qing Tian,  Chen Cao,  Weijian Qiu,  Han Wu,  Lijun Zhou,  Zhipeng Dai,  Zhenwei Li,  Songfeng Chen, 
  • First Published: 19 November 2021
Review Article
Open Access

Tendon Tissue Repair in Prospective of Drug Delivery, Regenerative Medicines, and Innovative Bioscaffolds

Muhammad Nadeem Hafeez,  Nicola d’Avanzo,  Valentina Russo,  Luisa Di Marzio,  Felisa Cilurzo,  Donatella Paolino,  Massimo Fresta,  Barbara Barboni,  Hélder A. Santos,  Christian Celia, 
  • First Published: 16 November 2021
Review Article
Open Access

Role of the Microenvironment in Mesenchymal Stem Cell-Based Strategies for Treating Human Liver Diseases

Shan-jing Xu,  Li-ping Ye,  Wei Wang,  Ya-hong Chen,  Jian Dong,  Xin-li Mao,  Shao-wei Li, 
  • First Published: 16 November 2021
Research Article
Open Access

Curcumin and Mesenchymal Stem Cells Ameliorate Ankle, Testis, and Ovary Deleterious Histological Changes in Arthritic Rats via Suppression of Oxidative Stress and Inflammation

Rania H. Ahmed,  Sanaa R. Galaly,  Nadia Moustafa,  Rasha Rashad Ahmed,  Tarek M. Ali,  Basem H. Elesawy,  Osama M. Ahmed,  Manal Abdul-Hamid, 
  • First Published: 09 November 2021
Review Article
Open Access

Classification and Characteristics of Mesenchymal Stem Cells and Its Potential Therapeutic Mechanisms and Applications against Ischemic Stroke

Pian Gong,  Wei Zhang,  Yan He,  Jianfeng Wang,  Song Li,  Songyu Chen,  Qingsong Ye,  Mingchang Li, 
  • First Published: 09 November 2021
Research Article
Open Access

SDF-1α Facilitates Mesenchymal Stem Cells to Induce Regulatory B Cell Differentiation from Patients with Immune Thrombocytopenia

Zhe Chen,  Shufen Zhou,  Jianyun Li,  Hui Li,  Can Huang,  Qin Guo,  Tiantian Zhang,  Bingya Yang,  Chuanqing Tu,  Chengshan Guo, 
  • First Published: 08 November 2021
Research Article
Open Access

Chemically Defined Conditions Mediate an Efficient Induction of Dental Pulp Pluripotent-Like Stem Cells into Hepatocyte-Like Cells

Carlos Gil-Recio,  Sheyla Montori,  Saddam Al Demour,  Mera A. Ababneh,  Eduard Ferrés-Padró,  Carles Marti,  Elvira Ferrés-Amat,  Miguel Barajas,  Ashraf Al Madhoun,  Maher Atari, 
  • First Published: 08 November 2021
Research Article
Open Access

Sox9-Increased miR-322-5p Facilitates BMP2-Induced Chondrogenic Differentiation by Targeting Smad7 in Mesenchymal Stem Cells

Yongsheng Zeng,  Chengcheng Du,  Pengcheng Xiao,  Yiting Lei,  Piao Zhao,  Zhenglin Zhu,  Shengqiang Gao,  Bowen Chen,  Shengwen Cheng,  Wei Huang,  Chen Zhao, 
  • First Published: 05 November 2021
Review Article
Open Access

Spatial-Temporal Patterns and Inflammatory Factors of Bone Matrix Remodeling

Jiechen Wang,  Fengyuan Guo,  Guangjin Chen,  Jiwei Sun,  Qingming Tang,  Lili Chen, 
  • First Published: 03 November 2021
Review Article
Open Access

The Clinical Trials of Mesenchymal Stromal Cells Therapy

Mohammad Reza Kouchakian,  Neda Baghban,  Seyedeh Farzaneh Moniri,  Mandana Baghban,  Shabnam Bakhshalizadeh,  Vahid Najafzadeh,  Zahra Safaei,  Safoura Izanlou,  Arezoo Khoradmehr,  Iraj Nabipour,  Reza Shirazi,  Amin Tamadon, 
  • First Published: 03 November 2021
Review Article
Open Access

The Role of RNA Methylation in Regulating Stem Cell Fate and Function-Focus on m6A

Weiwei Sun,  Bin Zhang,  Qingli Bie,  Na Ma,  Na Liu,  Zewei Shao, 
  • First Published: 28 October 2021
Research Article
Open Access

Human Umbilical Cord-Mesenchymal Stem Cells Survive and Migrate within the Vitreous Cavity and Ameliorate Retinal Damage in a Novel Rat Model of Chronic Glaucoma

Yao Wang,  Jiexuan Lv,  Changquan Huang,  Xiaohong Li,  Yongxiong Chen,  Wutian Wu,  Renyi Wu, 
  • First Published: 25 October 2021
Research Article
Open Access

Therapeutic Effect of Stem Cells on Male Infertility in a Rat Model: Histological, Molecular, Biochemical, and Functional Study

Sally S. Mohammed,  Mona F. Mansour,  Noha A. Salem, 
  • First Published: 25 October 2021
Research Article
Open Access

Activated Human Umbilical Cord Blood Platelet-Rich Plasma Enhances the Beneficial Effects of Human Umbilical Cord Mesenchymal Stem Cells in Chemotherapy-Induced POF Rats

Jiawei Wang,  Yunxiao Zhao,  Fengque Zheng,  Nana Ma,  Rongyan Qin,  Weili Qin,  Bo Liu,  Aiping Qin, 
  • First Published: 25 October 2021
Research Article
Open Access

SOX12 Promotes Stem Cell-Like Phenotypes and Osteosarcoma Tumor Growth by Upregulating JAGGED1

Weifei Zhang,  Fei Yu,  Jian Weng,  Yien Zheng,  Jianjing Lin,  Tiantian Qi,  Yihao Wei,  Deli Wang,  Hui Zeng, 
  • First Published: 23 October 2021
Research Article
Open Access

METTL3-Mediated m6A RNA Modification Regulates Corneal Injury Repair

Yarong Dai,  Maosheng Cheng,  Siyan Zhang,  Rongsong Ling,  Jieqi Wen,  Yifan Cheng,  Boxuan Huang,  Jinrong Li,  Caifeng Dai,  Shiqing Mao,  Shuibin Lin,  Huangxuan Shen,  Yizhou Jiang, 
  • First Published: 22 October 2021
Research Article
Open Access

miR-20a Overexpression in Adipose-Derived Mesenchymal Stem Cells Promotes Therapeutic Efficacy in Murine Lupus Nephritis by Regulating Autophagy

Shanshan Wei,  Zhiwen Zhang,  Lu Yan,  Yinjuan Mo,  Xianwen Qiu,  Xiangbin Mi,  Kuan Lai, 
  • First Published: 21 October 2021
Research Article
Open Access

Human Umbilical Mesenchymal Stromal Cells Mixed with Hyaluronan Transplantation Decreased Cartilage Destruction in a Rabbit Osteoarthritis Model

Yu-Hsun Chang,  Dah-Ching Ding,  Kun-Chi Wu, 
  • First Published: 21 October 2021
Research Article
Open Access

Phase I Trial of Intra-arterial Administration of Autologous Bone Marrow-Derived Mesenchymal Stem Cells in Patients with Multiple System Atrophy

Seok Jong Chung,  Tae Yong Lee,  Yang Hyun Lee,  KyoungWon Baik,  Jin Ho Jung,  Han Soo Yoo,  Chang Jae Shim,  Hyojin Eom,  Ji-Yeon Hong,  Dong Joon Kim,  Young H. Sohn,  Phil Hyu Lee, 
  • First Published: 19 October 2021
Research Article
Open Access

lncRNA-KCNQ1OT1: A Potential Target in Exosomes Derived from Adipose-Derived Stem Cells for the Treatment of Osteoporosis

Shan-zheng Wang,  Jun Jia,  Chang-hong Chen, 
  • First Published: 19 October 2021
Research Article
Open Access

Retinal Lineage Therapeutic Specific Effect of Human Orbital and Abdominal Adipose-Derived Mesenchymal Stem Cells

Bryan Krief,  Shira Weisthal Algor,  Itay Nakdimon,  Ayala Elhikis,  Moshe Benhamou,  Anouk Savir Kadmon,  Shay Keren,  Oded Ohana,  Ilan Feldman,  Ran Ben Cnaan,  Igal Leibovitch,  Anat Loewenstein,  Adiel Barak,  Aya Barzelay, 
  • First Published: 19 October 2021
Research Article
Open Access

Characteristics of Mesenchymal Stem Cells Are Independent of Bone Marrow Storage Temperatures

Valentin Schrodi,  Claudia Neunaber,  Katrin Bundkirchen,  Weikang Ye,  Zhida Jiang,  Maximilian Petri,  Christian Krettek,  Sandra Noack, 
  • First Published: 19 October 2021
Research Article
Open Access

Characterization and Study of Gene Expression Profiles of Human Periodontal Mesenchymal Stem Cells in Spheroid Cultures by Transcriptome Analysis

Takenori Suga,  Michihiko Usui,  Satoru Onizuka,  Kotaro Sano,  Tsuyoshi Sato,  Kohji Nakazawa,  Wataru Ariyoshi,  Tatsuji Nishihara,  Keisuke Nakashima, 
  • First Published: 19 October 2021
Review Article
Open Access

PRMT7: A Pivotal Arginine Methyltransferase in Stem Cells and Development

Bingyuan Wang,  Mingrui Zhang,  Zhiguo Liu,  Yulian Mu,  Kui Li, 
  • First Published: 19 October 2021
Research Article
Open Access

mTORC2 Activation Mediated by Mesenchymal Stem Cell-Secreted Hepatocyte Growth Factors for the Recovery of Lipopolysaccharide-Induced Vascular Endothelial Barrier

Shan-Shan Meng,  Feng-Mei Guo,  Li-Li Huang,  Ying-Zi Huang,  Jian-Feng Xie,  Cong-Shan Yang,  Hai-Bo Qiu,  Yi Yang, 
  • First Published: 18 October 2021
Review Article
Open Access

Transposable Element Dynamics and Regulation during Zygotic Genome Activation in Mammalian Embryos and Embryonic Stem Cell Model Systems

Yixuan Low,  Dennis Eng Kiat Tan,  Zhenhua Hu,  Shawn Ying Xuan Tan,  Wee-Wei Tee, 
  • First Published: 15 October 2021
Research Article
Open Access

Exosomes Derived from miR-146a-5p-Enriched Mesenchymal Stem Cells Protect the Cardiomyocytes and Myocardial Tissues in the Polymicrobial Sepsis through Regulating MYBL1

Chun Liu,  Jianhua Xue,  Bo Xu,  Aixian Zhang,  Lili Qin,  Jiajia Liu,  Yang Yang, 
  • First Published: 15 October 2021
Research Article
Open Access

Adipose Mesenchymal Stem Cell-Derived Exosomes Enhance PC12 Cell Function through the Activation of the PI3K/AKT Pathway

Yong Xie,  Yangping Chen,  Yuyuan Zhu,  Xia Chen,  Tiecheng Lin,  Dan Zhou, 
  • First Published: 15 October 2021
Research Article
Open Access

A Novel Cancer Stemness-Related Signature for Predicting Prognosis in Patients with Colon Adenocarcinoma

Wei Wang,  Congrong Xu,  Yan Ren,  Shiwei Wang,  Chunli Liao,  Xiaoyan Fu,  Haixia Hu, 
  • First Published: 15 October 2021
Research Article
Open Access

ALK5 i II Accelerates Induction of Adipose-Derived Stem Cells toward Schwann Cells through a Non-Smad Signaling Pathway

Seiji Sawai,  Tsunao Kishida,  Shin-ichiro Kotani,  Shinji Tsuchida,  Ryo Oda,  Hiroyoshi Fujiwara,  Kenji Takahashi,  Osam Mazda,  Yoshihiro Sowa, 
  • First Published: 15 October 2021

Research Article
Open Access

Hyperosmotic Stress Induces a Specific Pattern for Stress Granule Formation in Human-Induced Pluripotent Stem Cells

Salam Salloum-Asfar,  Rudolf Engelke,  Hanaa Mousa,  Neha Goswami,  I. Richard Thompson,  Freshteh Palangi,  Kamal Kamal,  Muna N. Al-Noubi,  Frank Schmidt,  Sara A. Abdulla,  Mohamed M. Emara, 
  • First Published: 15 October 2021
Review Article
Open Access

Stem Cell Therapy and Exercise for Treatment of Intervertebral Disc Degeneration

Bo Li,  Yunmei Yang,  Lan Wang,  Guanghua Liu, 
  • First Published: 13 October 2021
Review Article
Open Access

Recent Advances in Three-Dimensional Stem Cell Culture Systems and Applications

Xiaowen Wu,  Junxiang Su,  Jizhen Wei,  Nan Jiang,  Xuejun Ge, 
  • First Published: 11 October 2021
Research Article
Open Access

Characterization and miRNA Profiling of Extracellular Vesicles from Human Osteoarthritic Subchondral Bone Multipotential Stromal Cells (MSCs)

Clara Sanjurjo-Rodríguez,  Rachel E. Crossland,  Monica Reis,  Hemant Pandit,  Xiao-nong Wang,  Elena Jones, 
  • First Published: 09 October 2021
Research Article
Open Access

Rho/ROCK Inhibition Promotes TGF-β3-Induced Tenogenic Differentiation in Mesenchymal Stromal Cells

Michaela Melzer,  Susanna Schubert,  Simon Franz Müller,  Joachim Geyer,  Alina Hagen,  Sabine Niebert,  Janina Burk, 
  • First Published: 08 October 2021
Research Article
Open Access

KIF2C Is a Novel Prognostic Biomarker and Correlated with Immune Infiltration in Endometrial Cancer

Lanfen An,  Jun Zhang,  Dilu Feng,  Yingchao Zhao,  Weixiang Ouyang,  Rui Shi,  Xing Zhou,  Zhicheng Yu,  Sitian Wei,  Jie Min,  Hongbo Wang, 
  • First Published: 05 October 2021
Research Article
Open Access

Palmitic Acid Methyl Ester Enhances Adipogenic Differentiation in Rat Adipose Tissue-Derived Mesenchymal Stem Cells through a G Protein-Coupled Receptor-Mediated Pathway

Jian-Hong Lin,  Huan-Hsin Chang,  Wen-Sen Lee,  Pei-Ching Ting,  Yu-Po Luo,  Kun-Ta Yang, 
  • First Published: 05 October 2021
Research Article
Open Access

The Antimicrobial, Antioxidative, and Anti-Inflammatory Effects of Polycaprolactone/Gelatin Scaffolds Containing Chrysin for Regenerative Endodontic Purposes

Mahdieh Alipour,  Bahareh Pouya,  Zahra Aghazadeh,  Hossein SamadiKafil,  Marjan Ghorbani,  Sara Alizadeh,  Marziyeh Aghazadeh,  Elaheh Dalir Abdolahinia, 
  • First Published: 30 September 2021
Review Article
Open Access

Pharmacological Approaches and Regeneration of Bone Defects with Dental Pulp Stem Cells

M. Adamička,  A. Adamičková,  L. Danišovič,  A. Gažová,  J. Kyselovič, 
  • First Published: 29 September 2021
Review Article
Open Access

Cell-Based Transplantation versus Cell Homing Approaches for Pulp-Dentin Complex Regeneration

Geraldine M. Ahmed,  Eman A. Abouauf,  Nermeen AbuBakr,  Asmaa M. Fouad,  Christof E. Dörfer,  Karim M. Fawzy El-Sayed, 
  • First Published: 29 September 2021
Research Article
Open Access

[Retracted] Severity Assessment of COVID-19 Using a CT-Based Radiomics Model

Zhigao Xu,  Lili Zhao,  Guoqiang Yang,  Ying Ren,  Jinlong Wu,  Yuwei Xia,  Xuhong Yang,  Milan Cao,  Guojiang Zhang,  Taisong Peng,  Jiafeng Zhao,  Hui Yang,  Jinfeng Hu,  Jiangfeng Du, 
  • First Published: 27 September 2021

Research Article
Open Access

Neu5Ac Induces Human Dental Pulp Stem Cell Osteo-/Odontoblastic Differentiation by Enhancing MAPK/ERK Pathway Activation

Changzhou Li,  Xinghuan Xie,  Zhongjun Liu,  Jianhua Yang,  Daming Zuo,  Shuaimei Xu, 
  • First Published: 23 September 2021
Review Article
Open Access

Design and Optimization of the Circulatory Cell-Driven Drug Delivery Platform

Pengyu Gao,  Dan Zou,  Ansha Zhao,  Ping Yang, 
  • First Published: 22 September 2021
Research Article
Open Access

Intestinal Organoids in Colitis Research: Focusing on Variability and Cryopreservation

Talke F. zur Bruegge,  Andrea Liese,  Sören Donath,  Stefan Kalies,  Maike Kosanke,  Oliver Dittrich-Breiholz,  Sandra Czech,  Verena N. Bauer,  André Bleich,  Manuela Buettner, 
  • First Published: 18 September 2021
Research Article
Open Access

Stable Long-Term Culture of Human Distal Airway Stem Cells for Transplantation

Yueqing Zhou,  Yujia Wang,  Dandan Li,  Ting Zhang,  Yu Ma,  Wei Zuo, 
  • First Published: 17 September 2021
Review Article
Open Access

Applications of piggyBac Transposons for Genome Manipulation in Stem Cells

Yi Sun,  Guang Liu,  Yue Huang, 
  • First Published: 16 September 2021
Review Article
Open Access

Stem Cell-Derived Nanovesicles: A Novel Cell-Free Therapy for Wound Healing

Jianghong Huang,  Jun Zhang,  Jianyi Xiong,  Shuqing Sun,  Jiang Xia,  Lei Yang,  Yujie Liang, 
  • First Published: 15 September 2021
Review Article
Open Access

Clinical Efficacy and Safety of Human Mesenchymal Stem Cell Therapy for Degenerative Disc Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Baocheng Xie,  Shichun Chen,  Yongxiang Xu,  Weichao Han,  Runkai Hu,  Minyi Chen,  Ruirong He,  Shaobo Ding, 
  • First Published: 14 September 2021
Research Article
Open Access

Human Umbilical Cord Mesenchymal Stem Cell-Derived Extracellular Vesicles Promote the Proliferation of Schwann Cells by Regulating the PI3K/AKT Signaling Pathway via Transferring miR-21

Yongbin Ma,  Dan Zhou,  Huanyan Zhang,  Liming Tang,  Fen Qian,  Jianhua Su, 
  • First Published: 13 September 2021
Research Article
Open Access

Wnt/β-Catenin Pathway Balances Scaffold Degradation and Bone Formation in Tissue-Engineered Laminae

Hailong Li,  Linli Li,  Yiqun He,  Wei Mao,  Haofei Ni,  Aolei Yang,  Feizhou Lyu,  Youhai Dong, 
  • First Published: 13 September 2021
Research Article
Open Access

Functional Analysis of Ectodysplasin-A Mutations in X-Linked Nonsyndromic Hypodontia and Possible Involvement of X-Chromosome Inactivation

Yuhua Pan,  Ting Lu,  Ling Peng,  Qi Zeng,  Xiangyu Huang,  Xinchen Yao,  Buling Wu,  Fu Xiong, 
  • First Published: 11 September 2021
Review Article
Open Access

Brain Organoids: Studying Human Brain Development and Diseases in a Dish

Jie Xu,  Zhexing Wen, 
  • First Published: 10 September 2021
Review Article
Open Access

Strategies to Improve the Quality and Freshness of Human Bone Marrow-Derived Mesenchymal Stem Cells for Neurological Diseases

Da Yeon Lee,  Sung Eun Lee,  Do Hyeon Kwon,  Saraswathy Nithiyanandam,  Mi Ha Lee,  Ji Su Hwang,  Shaherin Basith,  Jung Hwan Ahn,  Tae Hwan Shin,  Gwang Lee, 
  • First Published: 09 September 2021
Review Article
Open Access

An In Vitro and In Vivo Comparison of Osteogenic Differentiation of Human Mesenchymal Stromal/Stem Cells

Jamie Mollentze,  Chrisna Durandt,  Michael S. Pepper, 
  • First Published: 08 September 2021
Research Article
Open Access

Chondrogenic Potential of Human Dental Pulp Stem Cells Cultured as Microtissues

Rubén Salvador-Clavell,  José Javier Martín de Llano,  Lara Milián,  María Oliver,  Manuel Mata,  Carmen Carda,  María Sancho-Tello, 
  • First Published: 08 September 2021
Review Article
Open Access

The Immunomodulatory Properties of Mesenchymal Stem Cells Play a Critical Role in Inducing Immune Tolerance after Liver Transplantation

Shao-wei Li,  Yue Cai,  Xin-li Mao,  Sai-qin He,  Ya-hong Chen,  Ling-ling Yan,  Jing-jing Zhou,  Ya-qi Song,  Li-ping Ye,  Xian-bin Zhou, 
  • First Published: 07 September 2021
Research Article
Open Access

Changes in Methylation Patterns of Tumor Suppressor Genes during Extended Human Embryonic Stem Cell Cultures

Kyung Min Kang,  Jeoung Eun Lee,  Ji Eun Park,  Hyunjin Kim,  Hee Yeon Jang,  Minyeon Go,  Dong Ryul Lee,  Sung Han Shim, 
  • First Published: 07 September 2021
Research Article
Open Access

3D Spheroid Formation Using BMP-Loaded Microparticles Enhances Odontoblastic Differentiation of Human Dental Pulp Stem Cells

Tae-Jun Min,  Min Ji Kim,  Kyung-Jung Kang,  Yeoung Jo Jeoung,  Se Heang Oh,  Young-Joo Jang, 
  • First Published: 02 September 2021
Review Article
Open Access

Mesenchymal Stem Cell Therapy for Alzheimer’s Disease

A. E. Hernández,  E. García, 
  • First Published: 01 September 2021
Research Article
Open Access

Dental Pulp Mesenchymal Stem Cells Attenuate Limb Ischemia via Promoting Capillary Proliferation and Collateral Development in a Preclinical Model

Youfeng Li,  Yuning Zhang,  Hua Wang,  Chengfeng Sun,  Dongmei Liu,  Hongying Liu,  Jia He,  Furong Chen,  Weiting Wang,  Xi Jiang,  Chu-tse Wu,  Yuefeng Yang, 
  • First Published: 01 September 2021
Review Article
Open Access

Organoid Models for Salivary Gland Biology and Regenerative Medicine

Chen Zhao,  Cuida Meng,  Na Cui,  Jichao Sha,  Liwei Sun,  Dongdong Zhu, 
  • First Published: 30 August 2021
Research Article
Open Access

[Retracted] High-Resolution Microscopy to Learn the Nuclear Organization of the Living Yeast Cells

Renjie Wang,  Aiwen Huang,  Yan Wang,  Pengxin Mei,  He Zhu,  Qianqian Chen,  Sankui Xu, 
  • First Published: 30 August 2021

Research Article
Open Access

[Retracted] Study of the Structure and Properties of ZnS Utilized in a Fluorescence Biosensor

Y. Ren,  H. Zhou,  X. Wang,  Q. W. Liu,  X. D. Hou,  G. F. Zhang, 
  • First Published: 29 August 2021

Review Article
Open Access

Strategies to Improve the Efficiency of Transplantation with Mesenchymal Stem Cells for the Treatment of Ischemic Stroke: A Review of Recent Progress

Yongchang Li,  Wei Zhong,  Xiangqi Tang, 
  • First Published: 28 August 2021
Research Article
Open Access

Proteomic Analysis of Hypoxia-Induced Senescence of Human Bone Marrow Mesenchymal Stem Cells

Liping Mai,  Guodong He,  Jing Chen,  Jiening Zhu,  Shaoxian Chen,  Xinghua Hou,  Hui Yang,  Mengzhen Zhang,  Yueheng Wu,  Qiuxiong Lin,  Min Yang,  Xiaohong Li, 
  • First Published: 27 August 2021
Research Article
Open Access

Towards Secretome Standardization: Identifying Key Ingredients of MSC-Derived Therapeutic Cocktail

Chiara Giannasi,  Stefania Niada,  Elena Della Morte,  Sara Casati,  Marica Orioli,  Alice Gualerzi,  Anna Teresa Brini, 
  • First Published: 26 August 2021
Research Article
Open Access

Effect of Activated Platelet-Rich Plasma on Chondrogenic Differentiation of Rabbit Bone Marrow-Derived Mesenchymal Stem Cells

Zhen Wang,  Zheng Wang,  Bin Zhang,  Qinghua Zhao,  Yubao Liu,  Wei Qi, 
  • First Published: 26 August 2021
Research Article
Open Access

miR-370-3p as a Novel Biomarker Promotes Breast Cancer Progression by Targeting FBLN5

Jiahui Mao,  Lingxia Wang,  Junying Wu,  Yichun Wang,  Huiyan Wen,  Xueming Zhu,  Bo Wang,  Huan Yang, 
  • First Published: 24 August 2021
Research Article
Open Access

Integration of Umbilical Cord Mesenchymal Stem Cell Application in Hydroxyapatite-Based Scaffolds in the Treatment of Vertebral Bone Defect due to Spondylitis Tuberculosis: A Translational Study

Ahmad Jabir Rahyussalim,  Ahmad Nugroho,  Muhammad Luqman Labib Zufar,  Irfan Fathurrahman,  Tri Kurniawati, 
  • First Published: 24 August 2021
Review Article
Open Access

Exosomes: Emerging Therapy Delivery Tools and Biomarkers for Kidney Diseases

Can Jin,  Peipei Wu,  Linli Li,  Wenrong Xu,  Hui Qian, 
  • First Published: 23 August 2021
Review Article
Open Access

Comparing the Therapeutic Potential of Stem Cells and their Secretory Products in Regenerative Medicine

Jhi Biau Foo,  Qi Hao Looi,  Pan Pan Chong,  Nur Hidayah Hassan,  Genieve Ee Chia Yeo,  Chiew Yong Ng,  Benson Koh,  Chee Wun How,  Sau Har Lee,  Jia Xian Law, 
  • First Published: 20 August 2021
Research Article
Open Access

Protective Effect of Adipose-Derived Mesenchymal Stem Cell Secretome against Hepatocyte Apoptosis Induced by Liver Ischemia-Reperfusion with Partial Hepatectomy Injury

Zhihui Jiao,  Yajun Ma,  Yue Wang,  Tao Liu,  Qianzhen Zhang,  Xiaoning Liu,  Chenxi Piao,  Boyang Liu,  Hongbin Wang, 
  • First Published: 19 August 2021
Research Article
Open Access

Microenvironment Influences on Human Umbilical Cord Mesenchymal Stem Cell-Based Bone Regeneration

Lingling E,  Rongjian Lu,  Jianwei Sun,  Hongbo Li,  Wen Xu,  Helin Xing,  Xing Wang,  Tao Cheng,  Shuo Zhang,  Xiaocao Ma,  Rong Zhang,  Hongchen Liu, 
  • First Published: 17 August 2021
Review Article
Open Access

An Overview of the Safety, Efficiency, and Signal Pathways of Stem Cell Therapy for Systemic Lupus Erythematosus

Qian Yang,  Yiping Liu,  Guangyong Chen,  Wancong Zhang,  Shijie Tang,  Tianbiao Zhou, 
  • First Published: 16 August 2021
Review Article
Open Access

Specific Blood Cells Derived from Pluripotent Stem Cells: An Emerging Field with Great Potential in Clinical Cell Therapy

Qian Luo,  Honghu Li,  Wei Shan,  Cong Wei,  Yan Long,  Shuyang Cai,  Xiangjun Zeng,  Xue Li,  Yulin Xu,  Xiaoxiao Xu,  Yi Luo,  Pengxu Qian,  He Huang, 
  • First Published: 15 August 2021
Editorial
Open Access

Stem Cell Applications in Regenerative Medicine for Kidney Diseases

Érika B. Rangel,  Cláudia O. Rodrigues,  Nádia K. Guimarães-Souza, 
  • First Published: 15 August 2021
Review Article
Open Access

Evaluation of the Efficacy of Stem Cell Therapy in Ovariectomized Osteoporotic Rats Based on Micro-CT and Dual-Energy X-Ray Absorptiometry: A Systematic Review and Meta-Analysis

Zhencheng Xiong,  Ping Yi,  Jialiang Lin,  Shengfeng Qiu,  Li Shu,  Chi Zhang, 
  • First Published: 15 August 2021
Research Article
Open Access

A Novel High-Content Screening-Based Method for Anti-Trypanosoma cruzi Drug Discovery Using Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes

Diogo Crispim Nascimento Portella,  Erik Aranha Rossi,  Bruno Diaz Paredes,  Tanira Matutino Bastos,  Cássio Santana Meira,  Carolina Vasques Kymie Nonaka,  Daniela Nascimento Silva,  Alex Improta-Caria,  Diogo Rodrigo Magalhaes Moreira,  Ana Cristina Lima Leite,  Gevanio Bezerra de Oliveira Filho,  José Maria Barbosa Filho,  Ricardo Ribeiro dos Santos,  Milena Botelho Pereira Soares,  Bruno Solano de Freita Souza, 
  • First Published: 15 August 2021
Research Article
Open Access

SDF-1α/OPF/BP Composites Enhance the Migrating and Osteogenic Abilities of Mesenchymal Stem Cells

Linli Li,  Xifeng Liu,  Bipin Gaihre,  Sungjo Park,  Yong Li,  Andre Terzic,  Lichun Lu, 
  • First Published: 15 August 2021
Research Article
Open Access

Gli1+ Cells Residing in Bone Sutures Respond to Mechanical Force via IP3R to Mediate Osteogenesis

Xiaoyao Huang,  Zihan Li,  Peisheng Liu,  Meiling Wu,  An-qi Liu,  Chenghu Hu,  Xuemei Liu,  Hao Guo,  Xiaoxue Yang,  Xiaohe Guo,  Bei Li,  Xiaoning He,  Kun Xuan,  Yan Jin, 
  • First Published: 15 August 2021

Research Article
Open Access

Adult Human Multipotent Neural Cells Could Be Distinguished from Other Cell Types by Proangiogenic Paracrine Effects via MCP-1 and GRO

Sung Soo Kim,  Hee-Jang Pyeon,  Yoon Kyung Bae,  Hyun Nam,  Chung Kwon Kim,  Sun-Ho Lee,  Kyeung Min Joo, 
  • First Published: 15 August 2021
Review Article
Open Access

Applications of Mesenchymal Stem Cells in Liver Fibrosis: Novel Strategies, Mechanisms, and Clinical Practice

Mengmei Zhu,  Tianzhen Hua,  Tao Ouyang,  Huofu Qian,  Bing Yu, 
  • First Published: 15 August 2021
Review Article
Open Access

Maxillofacial-Derived Mesenchymal Stem Cells: Characteristics and Progress in Tissue Regeneration

Xin Yan,  Fei Yan,  Hanan Abdulfattah Gamal Mohammed,  Ousheng Liu, 
  • First Published: 10 August 2021
Research Article
Open Access

A Novel Tension Machine Promotes Bone Marrow Mesenchymal Stem Cell Osteoblastic and Fibroblastic Differentiation by Applying Cyclic Tension

Yi Zhao,  Yiping Huang,  Lingfei Jia,  Ruoxi Wang,  Kuang Tan,  Weiran Li, 
  • First Published: 10 August 2021
Research Article
Open Access

CGF Membrane Promotes Periodontal Tissue Regeneration Mediated by hUCMSCs through Upregulating TAZ and Osteogenic Differentiation Genes

Wenjing Li,  Feifei Wang,  Fusheng Dong,  Zhiyong Zhang,  Peng Song,  Huizhen Chen,  Jie Wang, 
  • First Published: 05 August 2021
Research Article
Open Access

Optimal Pore Size of Honeycomb Polylactic Acid Films for In Vitro Cartilage Formation by Synovial Mesenchymal Stem Cells

Misaki Yagi,  Mitsuru Mizuno,  Ryota Fujisawa,  Hisako Katano,  Kentaro Endo,  Nobutake Ozeki,  Yuriko Sakamaki,  Hideyuki Koga,  Ichiro Sekiya, 
  • First Published: 03 August 2021
Review Article
Open Access

Application of Stem Cell Therapy for ACL Graft Regeneration

Canlong Wang,  Yejun Hu,  Shichen Zhang,  Dengfeng Ruan,  Zizhan Huang,  Peiwen He,  Honglu Cai,  Boon Chin Heng,  Xiao Chen,  Weiliang Shen, 
  • First Published: 02 August 2021
Research Article
Open Access

Intranasally Administered Extracellular Vesicles from Adipose Stem Cells Have Immunomodulatory Effects in a Mouse Model of Asthma

Sue Jean Mun,  Shin Ae Kang,  Hye-Kyung Park,  Hak Sun Yu,  Kyu-Sup Cho,  Hwan-Jung Roh, 
  • First Published: 31 July 2021
Review Article
Open Access

Intervertebral Disc Stem/Progenitor Cells: A Promising “Seed” for Intervertebral Disc Regeneration

Yuxiang Du,  Zhikun Wang,  Yangming Wu,  Chengyi Liu,  Lingli Zhang, 
  • First Published: 29 July 2021
Research Article
Open Access

Vimentin-Rab7a Pathway Mediates the Migration of MSCs and Lead to Therapeutic Effects on ARDS

Kai Wang,  Boxiang Du,  Yan Zhang,  Congyou Wu,  Xiuli Wang,  Xu Zhang,  Liwei Wang, 
  • First Published: 29 July 2021
Research Article
Open Access

Pharmacological Preconditioning Improves the Viability and Proangiogenic Paracrine Function of Hydrogel-Encapsulated Mesenchymal Stromal Cells

Francesco K. Touani,  Melanie Borie,  Feryel Azzi,  Dominique Trudel,  Nicolas Noiseux,  Shant Der Sarkissian,  Sophie Lerouge, 
  • First Published: 29 July 2021
Research Article
Open Access

Comparison between Intra-Articular Injection of Infrapatellar Fat Pad (IPFP) Cell Concentrates and IPFP-Mesenchymal Stem Cells (MSCs) for Cartilage Defect Repair of the Knee Joint in Rabbits

Yaguang Han,  Haobo Li,  Rong Zhou,  Jun Wu,  Ziye Liu,  Huan Wang,  Jiahua Shao,  Yi Chen,  Jun Zhu,  Qiwei Fu,  Qirong Qian,  Yiqin Zhou, 
  • First Published: 28 July 2021
Research Article
Open Access

Development of a Human Intestinal Organoid Model for In Vitro Studies on Gut Inflammation and Fibrosis

Leonidas Kandilogiannakis,  Eirini Filidou,  Ioannis Drygiannakis,  Gesthimani Tarapatzi,  Stylianos Didaskalou,  Maria Koffa,  Konstantinos Arvanitidis,  Giorgos Bamias,  Vassilis Valatas,  Vasilis Paspaliaris,  George Kolios, 
  • First Published: 27 July 2021
Review Article
Open Access

The Effects of Mesenchymal Stem Cell on Colorectal Cancer

Jintao Yuan,  Zhiping Wei,  Xinwei Xu,  Dickson Kofi Wiredu Ocansey,  Xiu Cai,  Fei Mao, 
  • First Published: 26 July 2021
Research Article
Open Access

Stem Cells from Human Exfoliated Deciduous Teeth (SHEDs) and Dental Pulp Stem Cells (DPSCs) Display a Similar Profile with Pericytes

Shao Yue Zhu,  Chang Yong Yuan,  Yi Fan Lin,  Hao Liu,  Yan Qi Yang,  Hai Ming Wong,  Cheng Fei Zhang,  Peng Lai Wang,  Min Gu, 
  • First Published: 26 July 2021
Review Article
Open Access

The Influence of the Surface Topographical Cues of Biomaterials on Nerve Cells in Peripheral Nerve Regeneration: A Review

Fang Liu,  Jiawei Xu,  Linliang Wu,  Tiantian Zheng,  Qi Han,  Yunyun Liang,  Liling Zhang,  Guicai Li,  Yumin Yang, 
  • First Published: 26 July 2021
Review Article
Open Access

Elucidating the Pivotal Neuroimmunomodulation of Stem Cells in Spinal Cord Injury Repair

Seidu A. Richard,  Marian Sackey, 
  • First Published: 24 July 2021
Research Article
Open Access

Epicardially Placed Bioengineered Cardiomyocyte Xenograft in Immune-Competent Rat Model of Heart Failure

Ikeotunye Royal Chinyere,  Pierce Bradley,  Joshua Uhlorn,  Joshua Eason,  Saffie Mohran,  Giuliana G. Repetti,  Sherry Daugherty,  Jen Watson Koevary,  Steven Goldman,  Jordan J. Lancaster, 
  • First Published: 24 July 2021
Research Article
Open Access

A Pilot Study Investigating the Expression Levels of Pluripotency-Associated Genes in Rectal Swab Samples for Colorectal Polyp and Cancer Diagnosis and Prognosis

Ryan Wai-Yan Sin,  Dominic Chi-Chung Foo,  Deepak Narayanan Iyer,  May Sau-Yee Fan,  Xue Li,  Oswens Siu-Hung Lo,  Wai-Lun Law,  Lui Ng, 
  • First Published: 23 July 2021
Review Article
Open Access

Osteogenic Differentiation of Mesenchymal Stem Cells via Curcumin-Containing Nanoscaffolds

Khadijeh Khezri,  Solmaz Maleki Dizaj,  Yalda Rahbar Saadat,  Simin Sharifi,  Shahriar Shahi,  Elham Ahmadian,  Aziz Eftekhari,  Elaheh Dalir Abdolahinia,  Farzaneh Lotfipour, 
  • First Published: 19 July 2021
Review Article
Open Access

Histone Acetylation in the Epigenetic Regulation of Bone Metabolism and Related Diseases

Qinglu Tian,  Shiqi Gao,  Xuedong Zhou,  Liwei Zheng,  Yachuan Zhou, 
  • First Published: 17 July 2021
Research Article
Open Access

miR-129-5p Promotes Osteogenic Differentiation of BMSCs and Bone Regeneration via Repressing Dkk3

Changming Zhao,  Yulin Gu,  Yan Wang,  Qiaozhen Qin,  Ting Wang,  Meng Huang,  Heyang Zhang,  Yannv Qu,  Jingwen Zhang,  Zhangzhen Du,  Xiao-Xia Jiang,  Lulu Xu, 
  • First Published: 16 July 2021
Review Article
Open Access

Roles of Mesenchymal Stem Cell-Derived Exosomes in Cancer Development and Targeted Therapy

Zixuan Sun,  Jiaxin Zhang,  Jiali Li,  Mi Li,  Jing Ge,  Peipei Wu,  Benshuai You,  Hui Qian, 
  • First Published: 12 July 2021
Research Article
Open Access

Pluripotency-State-Dependent Role of Dax1 in Embryonic Stem Cells Self-Renewal

Jianrong He,  Yuda Cheng,  Yan Ruan,  Jiali Wang,  Yanping Tian,  Jiaqi Wang,  Fengsheng Wang,  Chen Zhang,  Yixiao Xu,  Lianlian Liu,  Meng Yu,  Jiangjun Wang,  Binyu Zhao,  Yue Zhang,  Yi Yang,  Gaoke Liu,  Wei Wu,  Ping He,  Jiaxiang Xiong,  He Huang,  Junlei Zhang,  Rui Jian, 
  • First Published: 10 July 2021
Research Article
Open Access

Stiffness Regulates the Morphology, Adhesion, Proliferation, and Osteogenic Differentiation of Maxillary Schneiderian Sinus Membrane-Derived Stem Cells

Yiping Liu,  Jia Wang,  Peisong Zhai,  Sicong Ren,  Zhanqi Wang,  Peixuan Peng,  Liuyi Du,  Lisha Li,  Yidi Zhang,  Yanmin Zhou, 
  • First Published: 09 July 2021
Research Article
Open Access

Mesenchymal Stem Cell Sheet Promotes Functional Recovery and Palliates Neuropathic Pain in a Subacute Spinal Cord Injury Model

Kazuyoshi Yamazaki,  Masahito Kawabori,  Toshitaka Seki,  Soichiro Takamiya,  Kotaro Konno,  Masahiko Watanabe,  Kiyohiro Houkin,  Miki Fujimura, 
  • First Published: 09 July 2021
Research Article
Open Access

Heme Oxygenase-1-Modified Bone Marrow Mesenchymal Stem Cells Combined with Normothermic Machine Perfusion Repairs Bile Duct Injury in a Rat Model of DCD Liver Transplantation via Activation of Peribiliary Glands through the Wnt Pathway

Xuan Tian,  Huan Cao,  Longlong Wu,  Weiping Zheng,  Mengshu Yuan,  Xiang Li,  Hongli Song,  Zhongyang Shen, 
  • First Published: 05 July 2021
Research Article
Open Access

TAB2 Promotes the Stemness and Biological Functions of Cervical Squamous Cell Carcinoma Cells

Yijia Zhou,  Yuandong Liao,  Chunyu Zhang,  Junxiu Liu,  Wei Wang,  Jiaming Huang,  Qiqiao Du,  Tianyu Liu,  Qiaojian Zou,  Hua Huang,  Pan Liu,  Shiyin Ooi,  Run Chen,  Meng Xia,  Hongye Jiang,  Manman Xu,  Yuwen Pan,  Shuzhong Yao, 
  • First Published: 01 July 2021
Review Article
Open Access

FGF2 and EGF for the Regeneration of Tympanic Membrane: A Systematic Review

Zhengcai Lou,  Zihan Lou,  Yumeng Jiang,  Zhengnong Chen, 
  • First Published: 30 June 2021
Research Article
Open Access

Gastric Cancer Mesenchymal Stem Cells Inhibit NK Cell Function through mTOR Signalling to Promote Tumour Growth

Shuwei Guo,  Chao Huang,  Fengfeng Han,  Bin Chen,  Ying Ding,  Yuanyuan Zhao,  Zhihong Chen,  Shaodi Wen,  Mei Wang,  Bo Shen,  Wei Zhu, 
  • First Published: 30 June 2021
Research Article
Open Access

Proteomic Analysis Reveals Commonly Secreted Proteins of Mesenchymal Stem Cells Derived from Bone Marrow, Adipose Tissue, and Synovial Membrane to Show Potential for Cartilage Regeneration in Knee Osteoarthritis

Yura Lee,  Yo Seph Park,  Na Young Choi,  Yong Il Kim,  Yong-Gon Koh, 
  • First Published: 29 June 2021
Research Article
Open Access

Therapeutic Study of Thermosensitive Hydrogel Loaded with Super-Activated Platelet Lysate Combined with Core Decompression Technology for the Treatment of Femoral Head Necrosis

Zhipeng Huang,  Zhe Zhao,  Jun Lang,  Wantao Wang,  Yinsheng Fu,  Wenbo Wang, 
  • First Published: 28 June 2021
Research Article
Open Access

Icariin Promotes Survival, Proliferation, and Differentiation of Neural Stem Cells In Vitro and in a Rat Model of Alzheimer’s Disease

Denglei Ma,  Lihong Zhao,  Li Zhang,  Yali Li,  Lan Zhang,  Lin Li, 
  • First Published: 24 June 2021
Research Article
Open Access

Adipose-Derived Stem Cell-Derived Extracellular Vesicles Inhibit the Fibrosis of Fibrotic Buccal Mucosal Fibroblasts via the MicroRNA-375/FOXF1 Axis

Bin Han,  Yanhui Zhang,  Yuxia Xiao,  Bohong Shi,  Hong Wu,  Desheng Liu, 
  • First Published: 23 June 2021
Research Article
Open Access

Influence of Dental Pulp Harvesting Method on the Viability and Differentiation Capacity of Adult Dental Pulp-Derived Mesenchymal Stem Cells

Victor Okada Vendramini,  Sevda Pouraghaei,  Rafael Maza Barbosa,  Antônio Carlos Aloise,  José Ricardo Ferreira Muniz,  Marcelo Sperandio,  Peter Karyen Moy,  André Antonio Pelegrine,  Alireza Moshaverinia, 
  • First Published: 21 June 2021
Review Article
Open Access

3D Electrospun Nanofiber-Based Scaffolds: From Preparations and Properties to Tissue Regeneration Applications

Shanshan Han,  Kexin Nie,  Jingchao Li,  Qingqing Sun,  Xiaofeng Wang,  Xiaomeng Li,  Qian Li, 
  • First Published: 17 June 2021
Research Article
Open Access

Hydrostatic Pressure Modulates Intervertebral Disc Cell Survival and Extracellular Matrix Homeostasis via Regulating Hippo-YAP/TAZ Pathway

Yiyang Wang,  Baoshuai Bai,  Yanzhu Hu,  Haoming Wang,  Ningyuan Liu,  Yibo Li,  Pei Li,  Guangdong Zhou,  Qiang Zhou, 
  • First Published: 16 June 2021
Review Article
Open Access

Progress in Mesenchymal Stem Cell Therapy for Ischemic Stroke

Yinghan Guo,  Yucong Peng,  Hanhai Zeng,  Gao Chen, 
  • First Published: 15 June 2021
Review Article
Open Access

The Crosstalk between Mesenchymal Stem Cells and Macrophages in Bone Regeneration: A Systematic Review

Rita Lih-Ying Shin,  Chien-Wei Lee,  Oscar Yuan-Jie Shen,  Hongtao Xu,  Oscar Kuang-Sheng Lee, 
  • First Published: 15 June 2021
Review Article
Open Access

The Gingiva from the Tissue Surrounding the Bone to the Tissue Regenerating the Bone: A Systematic Review of the Osteogenic Capacity of Gingival Mesenchymal Stem Cells in Preclinical Studies

Gamilah Al-Qadhi,  Iman Aboushady,  Niyaz Al-Sharabi, 
  • First Published: 14 June 2021
Research Article
Open Access

Microfragmented Adipose Tissue Injection (MFAT) May Be a Solution to the Rationing of Total Knee Replacement: A Prospective, Gender-Bias Mitigated, Reproducible Analysis at Two Years

Nima Heidari,  Tiffanie-Marie Borg,  Stefano Olgiati,  Mark Slevin,  Alessandro Danovi,  Brady Fish,  Adrian Wilson,  Ali Noorani, 
  • First Published: 10 June 2021
Review Article
Open Access

Characteristics and Developments in Mesenchymal Stem Cell Therapy for COVID-19: An Update

Lu Sang,  Xiaoqin Guo,  Jie Shi,  Shike Hou,  Haojun Fan,  Qi Lv, 
  • First Published: 08 June 2021
Research Article
Open Access

miR-302d Competitively Binding with the lncRNA-341 Targets TLE4 in the Process of SSC Generation

Yani Zhang,  Wenhui Zhang,  Cai Hu,  Yingjie Wang,  Man Wang,  Qisheng Zuo,  Ahmed Kamel Elsayed,  Yi Li,  Bichun Li, 
  • First Published: 08 June 2021
Research Article
Open Access

Cell-Seeded Acellular Artery for Reconstruction of Long Urethral Defects in a Canine Model

Hao Zhong,  Yamei Shen,  Danhui Zhao,  Guoqiang Yan,  Chengai Wu,  Guanglin Huang,  Zhizhong Liu,  Jianpo Zhai,  Qin Han, 
  • First Published: 07 June 2021
Research Article
Open Access

A Comprehensive Prognostic and Immunological Analysis of a New Three-Gene Signature in Hepatocellular Carcinoma

Jun Liu,  Jianjun Lu,  Wenli Li, 
  • First Published: 03 June 2021
Research Article
Open Access

Long-Term Effects of Adjuvant Intravitreal Treatment with Autologous Bone Marrow-Derived Lineage-Negative Cells in Retinitis Pigmentosa

Marta P. Wiącek,  Wojciech Gosławski,  Aleksandra Grabowicz,  Anna Sobuś,  Miłosz P. Kawa,  Bartłomiej Baumert,  Edyta Paczkowska,  Sławomir Milczarek,  Bogumiła Osękowska,  Krzysztof Safranow,  Alicja Zawiślak,  Wojciech Lubiński,  Bogusław Machaliński,  Anna Machalińska, 
  • First Published: 03 June 2021
Review Article
Open Access

The Application Potential and Advance of Mesenchymal Stem Cell-Derived Exosomes in Myocardial Infarction

Xianyun Wang,  Yida Tang,  Zhao Liu,  Yajuan Yin,  Quanhai Li,  Gang Liu,  Baoyong Yan, 
  • First Published: 02 June 2021
Review Article
Open Access

Characteristics, Classification, and Application of Stem Cells Derived from Human Teeth

Tong Lei,  Xiaoshuang Zhang,  Hongwu Du, 
  • First Published: 31 May 2021
Research Article
Open Access

A Two-Stage Process for Differentiation of Wharton’s Jelly-Derived Mesenchymal Stem Cells into Neuronal-like Cells

Zaffar Equbal,  Prakash N. Baligar,  Madhulika Srivastava,  Asok Mukhopadhyay, 
  • First Published: 28 May 2021
Research Article
Open Access

Interleukin-20 Acts as a Promotor of Osteoclastogenesis and Orthodontic Tooth Movement

Yuanbo Liu,  Yilong Ai,  Xuan Sun,  Bowen Meng,  Xi Chen,  Dongle Wu,  Lei Gan,  Benyi Yang,  Chaoran Fu,  Yilin Wu,  Yang Cao, 
  • First Published: 26 May 2021
Review Article
Open Access

The Potential of Induced Pluripotent Stem Cells to Treat and Model Alzheimer’s Disease

Joseph M. Schulz, 
  • First Published: 26 May 2021
Research Article
Open Access

Early Osteogenic Differentiation Stimulation of Dental Pulp Stem Cells by Calcitriol and Curcumin

Mohammad Samiei,  Atefeh Abedi,  Simin Sharifi,  Solmaz Maleki Dizaj, 
  • First Published: 24 May 2021
Research Article
Open Access

Intranasally Administered L-Myc-Immortalized Human Neural Stem Cells Migrate to Primary and Distal Sites of Damage after Cortical Impact and Enhance Spatial Learning

Margarita Gutova,  Jeffrey P. Cheng,  Vikram Adhikarla,  Lusine Tsaturyan,  Michael E. Barish,  Russell C. Rockne,  Eleni H. Moschonas,  Corina O. Bondi,  Anthony E. Kline, 
  • First Published: 24 May 2021
Research Article
Open Access

HLA DR Genome Editing with TALENs in Human iPSCs Produced Immune-Tolerant Dendritic Cells

Yoo-Wook Kwon,  Hyo-Suk Ahn,  Jin-Woo Lee,  Han-Mo Yang,  Hyun-Jai Cho,  Seok Joong Kim,  Shin-Hyae Lee,  Heung-Mo Yang,  Hyun-Duk Jang,  Sung Joo Kim,  Hyo-Soo Kim, 
  • First Published: 21 May 2021
Research Article
Open Access

Biocompatibility and Angiogenic Effect of Chitosan/Graphene Oxide Hydrogel Scaffolds on EPCs

Lifang Zhang,  Xinping Li,  Congying Shi,  Gaoying Ran,  Yuting Peng,  Shuguang Zeng,  Yan He, 
  • First Published: 19 May 2021
Research Article
Open Access

China’s Stem Cell Research and Knowledge Levels of Medical Practitioners and Students

Deng Luo,  Zihui Xu,  Zhongjing Wang,  Wenzhuo Ran, 
  • First Published: 19 May 2021
Review Article
Open Access

Mesenchymal Stem Cells in Preclinical Infertility Cytotherapy: A Retrospective Review

Zhuo Chang,  Hui Zhu,  Xueming Zhou,  Yang Zhang,  Bei Jiang,  Shuoxi Li,  Lu Chen,  Xue Pan,  Xiao-ling Feng, 
  • First Published: 17 May 2021
Research Article
Open Access

Topical Application of bFGF Alone for the Regeneration of Chronic Tympanic Membrane Perforations: A Preliminary Case Series

Zihan Lou,  Zhengcai Lou,  Kangfeng Jin,  Junzhi Sun,  Zhengnong Chen, 
  • First Published: 17 May 2021
Research Article
Open Access

METTL3-Mediated m6A Methylation Regulates Muscle Stem Cells and Muscle Regeneration by Notch Signaling Pathway

Yu Liang,  Hui Han,  Qiuchan Xiong,  Chunlong Yang,  Lu Wang,  Jieyi Ma,  Shuibin Lin,  Yi-Zhou Jiang, 
  • First Published: 15 May 2021
Research Article
Open Access

Comparison of the Donor Age-Dependent and In Vitro Culture-Dependent Mesenchymal Stem Cell Aging in Rat Model

Katarzyna Siennicka,  Aleksandra Zołocińska,  Tomasz Dębski,  Zygmunt Pojda, 
  • First Published: 15 May 2021
Research Article
Open Access

Evaluation of Silk Fibroin-RGD-Stem Cell Factor Scaffold Effect on Adhesion, Migration, and Proliferation of Stem Cells of Apical Papilla

Jie Wei,  Xiao-Qiang Sun,  Ben-Xiang Hou, 
  • First Published: 10 May 2021
Review Article
Open Access

Key Markers and Epigenetic Modifications of Dental-Derived Mesenchymal Stromal Cells

Jingqiu Chen,  Xiaodan Zheng,  Nanquan Rao,  Yao Huang,  Juan Liu,  Yanhong Li,  Jun Zhang, 
  • First Published: 10 May 2021
Review Article
Open Access

Mesenchymal Stem Cells and COVID-19: Cure, Prevention, and Vaccination

Mehrdad Afarid,  Fatemeh Sanie-Jahromi, 
  • First Published: 07 May 2021
Corrigendum
Open Access

Corrigendum to “Evaluation of Novel Stereotactic Cannula for Stem Cell Transplantation against Central Nervous System Disease”

Masahito Kawabori,  Aki Tanimori,  Shinri Kitta,  Hideo Shichinohe,  Kiyohiro Houkin, 
  • First Published: 04 May 2021

Research Article
Open Access

[Retracted] Loading Gentamicin and Zn2+ on TiO2 Nanotubes to Improve Anticoagulation, Endothelial Cell Growth, and Antibacterial Activities

Yuebin Lin,  Li Zhang,  Ya Yang,  Minhui Yang,  Qingxiang Hong,  Keming Chang,  Juan Dai,  Lu Chen,  Changjiang Pan,  Youdong Hu,  Li Quan,  Yanchun Wei,  Sen Liu,  Zhongmei Yang, 
  • First Published: 04 May 2021

Review Article
Open Access

The Opportunities and Challenges regarding Induced Platelets from Human Pluripotent Stem Cells

Meng-Xue Xu,  Li-Ping Liu,  Yu-Mei Li,  Yun-Wen Zheng, 
  • First Published: 04 May 2021
Research Article
Open Access

Expression Profile of Long Noncoding RNAs and Circular RNAs in Mouse C3H10T1/2 Mesenchymal Stem Cells Undergoing Myogenic and Cardiomyogenic Differentiation

Mingshan Li,  Zijie Pei,  Hongtao Zhang,  Jing Qu, 
  • First Published: 30 April 2021
Review Article
Open Access

Stem Cells: A Historical Review about Biological, Religious, and Ethical Issues

Ioannis Alexandros Charitos,  Andrea Ballini,  Stefania Cantore,  Mariarosaria Boccellino,  Marina Di Domenico,  Elisa Borsani,  Riccardo Nocini,  Michele Di Cosola,  Luigi Santacroce,  Lucrezia Bottalico, 
  • First Published: 30 April 2021
Review Article
Open Access

Microgravity, Stem Cells, and Cancer: A New Hope for Cancer Treatment

Uğur Topal,  Cihan Zamur, 
  • First Published: 29 April 2021
Research Article
Open Access

Single-Cell Transcriptome Analysis of Human Adipose-Derived Stromal Cells Identifies a Contractile Cell Subpopulation

Elize Wolmarans,  Juanita Mellet,  Chrisna Durandt,  Fourie Joubert,  Michael S. Pepper, 
  • First Published: 29 April 2021
Review Article
Open Access

Cell-Based Therapies for the Treatment of Shoulder and Elbow Tendinopathies: A Scoping Review

Berardo Di Matteo,  Riccardo Ranieri,  Angelo Manca,  Simone Cappato,  Maurilio Marcacci,  Elizaveta Kon,  Alessandro Castagna, 
  • First Published: 27 April 2021
Research Article
Open Access

lncRNA HHIP-AS1 Promotes the Osteogenic Differentiation Potential and Inhibits the Migration Ability of Periodontal Ligament Stem Cells

Qianyi Qin,  Haoqing Yang,  Chen Zhang,  Xiao Han,  Jing Guo,  Zhipeng Fan,  Jie Guo, 
  • First Published: 27 April 2021
Research Article
Open Access

Surface Modification with NGF-Loaded Chitosan/Heparin Nanoparticles for Improving Biocompatibility of Cardiovascular Stent

Haixin Song,  Tao Wu,  Xiaotian Yang,  Yangzheng Li,  Ye Ye,  Bo Li,  Tao Liu,  Shihui Liu,  Jianhua Li, 
  • First Published: 26 April 2021
Corrigendum
Open Access

Corrigendum to “Therapeutic Effects of Human Urine-Derived Stem Cells in a Rat Model of Cisplatin-Induced Acute Kidney Injury In Vivo and In Vitro”

Bishao Sun,  Xing Luo,  Chengfei Yang,  Peilin Liu,  Yang Yang,  Xingyou Dong,  Zhenxing Yang,  JieXu,  Yuanyuan Zhang,  Longkun Li, 
  • First Published: 24 April 2021

Corrigendum
Open Access

Corrigendum to “Umbilical Cord Tissue-Derived Mesenchymal Stem Cells Induce T Lymphocyte Apoptosis and Cell Cycle Arrest by Expression of Indoleamine 2, 3-Dioxygenase”

Xiuying Li,  Zhuo Xu,  Jinping Bai,  Shuyuan Yang,  Shuli Zhao,  Yingjie Zhang,  Xiaodong Chen,  Yimin Wang, 
  • First Published: 24 April 2021

Research Article
Open Access

Bone Mesenchymal Stem Cells Contribute to Ligament Regeneration and Graft–Bone Healing after Anterior Cruciate Ligament Reconstruction with Silk–Collagen Scaffold

Fanggang Bi,  Yangdi Chen,  Junqi Liu,  Wenhao Hu,  Ke Tian, 
  • First Published: 24 April 2021
Research Article
Open Access

Functional Recovery after Intramyocardial Injection of Adipose-Derived Stromal Cells Assessed by Cardiac Magnetic Resonance Imaging

Janusz Konstanty-Kalandyk,  Jerzy Sadowski,  Anna Kędziora,  Małgorzata Urbańczyk-Zawadzka,  Jakub Baran,  Paweł Banyś,  Bogusław Kapelak,  Jacek Piątek, 
  • First Published: 23 April 2021
Review Article
Open Access

Electrical Stimulation Promotes Stem Cell Neural Differentiation in Tissue Engineering

Hong Cheng,  Yan Huang,  Hangqi Yue,  Yubo Fan, 
  • First Published: 21 April 2021
Research Article
Open Access

Exosomes from LPS-Stimulated hDPSCs Activated the Angiogenic Potential of HUVECs In Vitro

Xiangyu Huang,  Wei Qiu,  Yuhua Pan,  Jianjia Li,  Zhao Chen,  Kaiying Zhang,  Yifei Luo,  Buling Wu,  Wenan Xu, 
  • First Published: 15 April 2021
Research Article
Open Access

Positively Correlated CD47 Activation and Autophagy in Umbilical Cord Blood-Derived Mesenchymal Stem Cells during Senescence

Gee-Hye Kim,  Yun Kyung Bae,  Ji Hye Kwon,  Miyeon Kim,  Soo Jin Choi,  Wonil Oh,  Soyoun Um,  Hye Jin Jin, 
  • First Published: 15 April 2021
Letter to the Editor
Open Access

Comment on “Recent Advance in Source, Property, Differentiation, and Applications of Infrapatellar Fat Pad Adipose-Derived Stem Cells”

Elena Stocco,  Andrea Porzionato,  Raffaele De Caro,  Veronica Macchi, 
  • First Published: 14 April 2021

Research Article
Open Access

NAT10 Promotes Osteogenic Differentiation of Mesenchymal Stem Cells by Mediating N4-Acetylcytidine Modification of Gremlin 1

Zhenbiao Zhu,  Xiaowei Xing,  Shisi Huang,  Yuanyuan Tu, 
  • First Published: 13 April 2021
Research Article
Open Access

Long Noncoding RNA Expression Profiles of Periodontal Ligament Stem Cells from the Periodontitis Microenvironment in Response to Static Mechanical Strain

Jia Liu,  Yan Zhao,  Qiannan Niu,  Ni Qiu,  Shuangyun Liu,  Chunrong Li,  Cuixia Li,  Pei Miao,  Libo Yan,  Qiang Li,  Zuolin Jin, 
  • First Published: 12 April 2021
Research Article
Open Access

VEGF Contributes to Mesenchymal Stem Cell-Mediated Reversion of Nor1-Dependent Hypertrophy in iPS Cell-Derived Cardiomyocytes

Denise Philipp,  Michelle Holthaus,  Vida Basoah,  Kurt Pfannkuche,  Laura Suhr,  Thorsten Wahlers,  Adnana Paunel-Görgülü, 
  • First Published: 10 April 2021
Research Article
Open Access

Inhibition of Notch Signaling Promotes the Differentiation of Epicardial Progenitor Cells into Adipocytes

Bin Liu,  Dinghui Wang,  Tianhua Xiong,  Yajie Liu,  Xiaodong Jing,  Jianlin Du,  Qiang She, 
  • First Published: 09 April 2021
Research Article
Open Access

miR-375 Promotes Pancreatic Differentiation In Vitro by Affecting Different Target Genes at Different Stages

Zhenyu Lu,  Jing Wang,  Xu Wang,  Zhiying Li,  Dan Niu,  Min Wang,  Jinzhu Xiang,  Yongli Yue,  Yajuan Xia,  Xueling Li, 
  • First Published: 09 April 2021
Research Article
Open Access

Comparison of Osteogenic Differentiation Potential of Human Dental-Derived Stem Cells Isolated from Dental Pulp, Periodontal Ligament, Dental Follicle, and Alveolar Bone

Guanlin Qu,  Yan Li,  Lu Chen,  Qin Chen,  Duohong Zou,  Chi Yang,  Qing Zhou, 
  • First Published: 08 April 2021
Research Article
Open Access

Different Neurogenic Potential in the Subnuclei of the Postnatal Rat Cochlear Nucleus

Johannes Voelker,  Jonas Engert,  Christine Voelker,  Linda Bieniussa,  Philipp Schendzielorz,  Rudolf Hagen,  Kristen Rak, 
  • First Published: 07 April 2021
Research Article
Open Access

Continuous Inhibition of Sonic Hedgehog Signaling Leads to Differentiation of Human-Induced Pluripotent Stem Cells into Functional Insulin-Producing β Cells

Song Lee,  Jae Hyun Joo,  Ju Yun Oh,  Eun Ha Seo,  Yang Hee Kim,  Eunsung Jun,  In Kyong Shim,  Song Cheol Kim, 
  • First Published: 07 April 2021
Review Article
Open Access

Functional Properties of Human-Derived Mesenchymal Stem Cell Spheroids: A Meta-Analysis and Systematic Review

Sarah Ezquerra,  Amparo Zuleta,  Rodrigo Arancibia,  José Estay,  Francisco Aulestia,  Flavio Carrion, 
  • First Published: 05 April 2021
Research Article
Open Access

Potency of Bone Marrow-Derived Mesenchymal Stem Cells and Indomethacin in Complete Freund’s Adjuvant-Induced Arthritic Rats: Roles of TNF-α, IL-10, iNOS, MMP-9, and TGF-β1

Eman A. Ahmed,  Osama M. Ahmed,  Hanaa I. Fahim,  Tarek M. Ali,  Basem H. Elesawy,  Mohamed B. Ashour, 
  • First Published: 05 April 2021
Research Article
Open Access

Expression of CD146 and Regenerative Cytokines by Human Placenta-Derived Mesenchymal Stromal Cells upon Expansion in Different GMP-Compliant Media

Frederik Peissert,  Hannah D. E. Graf,  Bettina Müller,  Tanja Abruzzese,  Harald Abele,  Wilhelm K. Aicher, 
  • First Published: 02 April 2021
Review Article
Open Access

An Update on Mesenchymal Stem Cell-Centered Therapies in Temporomandibular Joint Osteoarthritis

Yifan Zhao,  Liang Xie, 
  • First Published: 02 April 2021
Review Article
Open Access

Regulatory Effect of Mesenchymal Stem Cells on T Cell Phenotypes in Autoimmune Diseases

Zhiping Wei,  Jintao Yuan,  Gaoying Wang,  Dickson Kofi Wiredu Ocansey,  Zhiwei Xu,  Fei Mao, 
  • First Published: 30 March 2021
Research Article
Open Access

Integrin-Linked Kinase (ILK) Regulates Urinary Stem Cells Differentiation into Smooth Muscle via NF-κB Signal Pathway

Liang-liang Huang,  Jun-hong Deng,  Jing-xuan Xie,  Zi-bin Lin,  Hui Jiang,  Bin Ouyang,  Jian-ming Liu,  Yan-ni Wei,  Zhou-da Cai, 
  • First Published: 27 March 2021
Research Article
Open Access

Fibrin Glue-Kartogenin Complex Promotes the Regeneration of the Tendon-Bone Interface in Rotator Cuff Injury

Jun Zhu,  Jiahua Shao,  Yi Chen,  Guangyi Zhao,  Lexiang Li,  Qiwei Fu,  Qirong Qian,  Qi Zhou,  Zheru Ding,  Yiqin Zhou, 
  • First Published: 27 March 2021
Review Article
Open Access

Photobiomodulation: An Effective Approach to Enhance Proliferation and Differentiation of Adipose-Derived Stem Cells into Osteoblasts

Daniella Da Silva,  Anine Crous,  Heidi Abrahamse, 
  • First Published: 24 March 2021
Review Article
Open Access

Recent Developed Strategies for Enhancing Chondrogenic Differentiation of MSC: Impact on MSC-Based Therapy for Cartilage Regeneration

Kangkang Zha,  Zhiqiang Sun,  Yu Yang,  Mingxue Chen,  Cangjiang Gao,  Liwei Fu,  Hao Li,  Xiang Sui,  Quanyi Guo,  Shuyun Liu, 
  • First Published: 22 March 2021
Research Article
Open Access

Exploring a Chemotactic Role for EVs from Progenitor Cell Populations of Human Exfoliated Deciduous Teeth for Promoting Migration of Naïve BMSCs in Bone Repair Process

Lin Luo,  Steven J. Avery,  Rachel J. Waddington, 
  • First Published: 17 March 2021
Review Article
Open Access

Mesenchymal Stem Cells: An Overview of Their Potential in Cell-Based Therapy for Diabetic Nephropathy

Yan Wu,  Chunlei Zhang,  Ran Guo,  Dan Wu,  Jiayi Shi,  Luxin Li,  Yanhui Chu,  Xiaohuan Yuan,  Jie Gao, 
  • First Published: 17 March 2021
Research Article
Open Access

Exposure of Mesenchymal Stem Cells to an Alzheimer’s Disease Environment Enhances Therapeutic Effects

Sang Eon Park,  Hyeong Seop Kim,  Soo Jin Kwon,  Min-Jeong Kim,  Suk-joo Choi,  Soo-young Oh,  Gyu Ha Ryu,  Hong Bae Jeon,  Duk L. Na,  Jong Wook Chang, 
  • First Published: 16 March 2021
Research Article
Open Access

Comparison of the Migration Potential through Microperforated Membranes of CD146+ GMSC Population versus Heterogeneous GMSC Population

Mohamed Al Bahrawy, 
  • First Published: 12 March 2021
Research Article
Open Access

Inhibition of Allogeneic and Autologous T Cell Proliferation by Adipose-Derived Mesenchymal Stem Cells of Ankylosing Spondylitis Patients

Ewa Kuca-Warnawin,  Magdalena Plebańczyk,  Krzysztof Bonek,  Ewa Kontny, 
  • First Published: 12 March 2021
Research Article
Open Access

Human ES Cell Culture Conditions Fail to Preserve the Mouse Epiblast State

A. S. Devika,  Anna Montebaur,  S. Saravanan,  Raghu Bhushan,  Frederic Koch,  Smita Sudheer, 
  • First Published: 10 March 2021
Research Article
Open Access

Evaluation of Clinical and Histological Outcomes of Adipose-Derived Mesenchymal Stem Cells in a Rabbit Corneal Alkali Burn Model

Diamantis Almaliotis,  Angelos Thomas,  Anastasia Komnenou,  Eleni Gounari,  Stavroula Almpanidou,  Thomas Siempis,  Nikolaos Papaioannou,  Georgios Koliakos,  Eleni Papakonstantinou,  Konstadinos Sotiropulos,  Vasileios Karampatakis, 
  • First Published: 09 March 2021
Research Article
Open Access

Exosomes from Kartogenin-Pretreated Infrapatellar Fat Pad Mesenchymal Stem Cells Enhance Chondrocyte Anabolism and Articular Cartilage Regeneration

Jiahua Shao,  Jun Zhu,  Yi Chen,  Qiwei Fu,  Lexiang Li,  Zheru Ding,  Jun Wu,  Yaguang Han,  Haobo Li,  Qirong Qian,  Yiqin Zhou, 
  • First Published: 09 March 2021
Research Article
Open Access

Lithium and Copper Induce the Osteogenesis-Angiogenesis Coupling of Bone Marrow Mesenchymal Stem Cells via Crosstalk between Canonical Wnt and HIF-1α Signaling Pathways

Zhen Tan,  Baochun Zhou,  Jianrui Zheng,  Yongcan Huang,  Hui Zeng,  Lixiang Xue,  Deli Wang, 
  • First Published: 08 March 2021
Research Article
Open Access

The Application of a Bone Marrow Mesenchymal Stem Cell Membrane in the Vascularization of a Decellularized Tracheal Scaffold

Zhi-Ye Yao,  Bo-Wen Feng,  Cai-Sheng Liu,  Yu-Mei Liu,  Hai-Yu Zhou,  Xiao-Hui Zhang,  Min-Qiao Jian,  Jian-Ling Mo,  Yi-Jing Liang,  Liang Chen,  Xiao-Qing Liu,  Yan-Ling Chen,  Zhan-Song Zhang,  Shao-Ru He, 
  • First Published: 08 March 2021
Corrigendum
Open Access

Corrigendum to “Bionic Silk Fibroin Film Promotes Tenogenic Differentiation of Tendon Stem/Progenitor Cells by Activating Focal Adhesion Kinase”

Kang Lu,  Xiaodie Chen,  Hong Tang,  Mei Zhou,  Gang He,  Zhisong Lu,  Kanglai Tang, 
  • First Published: 03 March 2021

Research Article
Open Access

Inhibition of Endoplasmic Reticulum Stress by 4-Phenyl Butyric Acid Presents Therapeutic Effects on Periodontitis: Experimental Studies In Vitro and in Rats

Yang Feng,  Rong Zhang,  Yi-rong Wang,  Fei Chen,  Qiang Luo,  Chuan Cai,  Yang Jiao,  Peng Xue, 
  • First Published: 03 March 2021
Research Article
Open Access

HGF-Modified Dental Pulp Stem Cells Mitigate the Inflammatory and Fibrotic Responses in Paraquat-Induced Acute Respiratory Distress Syndrome

Panpan Geng,  Yuning Zhang,  Huan Zhang,  Xiwen Dong,  Yuefeng Yang,  XiaoNa Zhu,  Chu-Tse Wu,  Hua Wang, 
  • First Published: 02 March 2021
Research Article
Open Access

The Impact of Various Culture Conditions on Human Mesenchymal Stromal Cells Metabolism

Pavla Tonarova,  Katerina Lochovska,  Robert Pytlik,  Marie Hubalek Kalbacova, 
  • First Published: 01 March 2021
Review Article
Open Access

The Regulation and Functions of Endogenous Retrovirus in Embryo Development and Stem Cell Differentiation

Yangquan Xiang,  Hongqing Liang, 
  • First Published: 28 February 2021
Research Article
Open Access

Semaphorin3B Promotes Proliferation and Osteogenic Differentiation of Bone Marrow Mesenchymal Stem Cells in a High-Glucose Microenvironment

Quan Xing,  Jingyi Feng,  Xiaolei Zhang, 
  • First Published: 26 February 2021
Review Article
Open Access

Efficiency of Stem Cell (SC) Differentiation into Insulin-Producing Cells for Treating Diabetes: a Systematic Review

Marzieh Nemati,  GolamHossein Ranjbar Omrani,  Bahareh Ebrahimi,  Aliakbar Alizadeh, 
  • First Published: 26 February 2021
Research Article
Open Access

Gender-Specific Response in Pain and Function to Biologic Treatment of Knee Osteoarthritis: A Gender-Bias-Mitigated, Observational, Intention-to-Treat Study at Two Years

Tiffanie-Marie Borg,  Nima Heidari,  Ali Noorani,  Mark Slevin,  Angela Cullen,  Stefano Olgiati,  Alberto Zerbi,  Alessandro Danovi,  Adrian Wilson, 
  • First Published: 26 February 2021
Research Article
Open Access

Human Chondrocytes from Human Adipose Tissue-Derived Mesenchymal Stem Cells Seeded on a Dermal-Derived Collagen Matrix Sheet: Our Preliminary Results for a Ready to Go Biotechnological Cartilage Graft in Clinical Practice

Quan Tran Dang,  Thao Duy Huynh,  Francesco Inchingolo,  Gianna Dipalma,  Alessio Danilo Inchingolo,  Stefania Cantore,  Gregorio Paduanelli,  Kieu Cao Diem Nguyen,  Andrea Ballini,  Ciro Gargiulo Isacco,  Cong Toai Tran, 
  • First Published: 24 February 2021
Review Article
Open Access

Clinical Application of Human Induced Pluripotent Stem Cell-Derived Organoids as an Alternative to Organ Transplantation

Gabriella Shih Ping Hsia,  Joyce Esposito,  Letícia Alves da Rocha,  Sofia Lígia Guimarães Ramos,  Oswaldo Keith Okamoto, 
  • First Published: 24 February 2021
Research Article
Open Access

Adventitial Progenitor Cells of Human Great Saphenous Vein Enhance the Resolution of Venous Thrombosis via Neovascularization

Siying Ling,  Zhen Ma,  Yong Teng,  Xuemei Jiang,  Junning Cheng,  Ruihao Li,  Mingyi Zhang,  Hailong Luo,  Yikuan Chen, 
  • First Published: 23 February 2021
Research Article
Open Access

Lin28 Inhibits the Differentiation from Mouse Embryonic Stem Cells to Glial Lineage Cells through Upregulation of Yap1

Juan Luo,  Hailin Zou,  Liang Deng,  Xiang Sun,  Ping Yuan,  Peng Li, 
  • First Published: 22 February 2021
Review Article
Open Access

Stromal Vascular Fraction and Amniotic Epithelial Cells: Preclinical and Clinical Relevance in Musculoskeletal Regenerative Medicine

Francesca Veronesi,  Melania Maglio,  Deyanira Contartese,  Lucia Martini,  Aurelio Muttini,  Milena Fini, 
  • First Published: 22 February 2021
Review Article
Open Access

Molecular Insights into the Potential of Extracellular Vesicles Released from Mesenchymal Stem Cells and Other Cells in the Therapy of Hematologic Malignancies

Suliman A. Alsagaby, 
  • First Published: 18 February 2021
Review Article
Open Access

Extracellular Vesicles: Novel Roles in Neurological Disorders

Qian Jin,  Peipei Wu,  Xinru Zhou,  Hui Qian,  Wenrong Xu, 
  • First Published: 17 February 2021
Research Article
Open Access

Combined Treatment of Adipose Derived-Mesenchymal Stem Cells and Pregabalin Is Superior to Monotherapy for the Treatment of Neuropathic Pain in Rats

Shimaa Mohammad Yousof,  Doaa Attia ElSayed,  Amani A. El-Baz,  Hanaa S. Sallam,  Faten Abbas, 
  • First Published: 15 February 2021
Research Article
Open Access

Ligustrum japonicum Thunb. Fruits Exert Antiosteoporotic Properties in Bone Marrow-Derived Mesenchymal Stromal Cells via Regulation of Adipocyte and Osteoblast Differentiation

Jung Hwan Oh,  Fatih Karadeniz,  Jung Im Lee,  Youngwan Seo,  Chang-Suk Kong, 
  • First Published: 15 February 2021
Review Article
Open Access

Research Progress on Stem Cell Therapies for Articular Cartilage Regeneration

Shuangpeng Jiang,  Guangzhao Tian,  Xu Li,  Zhen Yang,  Fuxin Wang,  Zhuang Tian,  Bo Huang,  Fu Wei,  Kangkang Zha,  Zhiqiang Sun,  Xiang Sui,  Shuyun Liu,  Weimin Guo,  Quanyi Guo, 
  • First Published: 12 February 2021
Editorial
Open Access

Reevolution of Tissue Regeneration: From Recent Advances in Adipose Stem Cells to Novel Therapeutic Approaches

Francesco De Francesco,  Csaba Matta,  Michele Riccio,  Andrea Sbarbati,  Ali Mobasheri, 
  • First Published: 11 February 2021
Research Article
Open Access

Clinical Trial of Allogeneic Mesenchymal Stem Cell Therapy for Chronic Active Antibody-Mediated Rejection in Kidney Transplant Recipients Unresponsive to Rituximab and Intravenous Immunoglobulin

Tae Hyun Ban,  Sua Lee,  Hyung Duk Kim,  Eun Jeong Ko,  Bo-Mi Kim,  Kyoung-Woon Kim,  Byung Ha Chung,  Chul Woo Yang, 
  • First Published: 11 February 2021
Review Article
Open Access

The Therapeutic Potential of Inflamed Gingiva-Derived Mesenchymal Stem Cells in Preclinical Studies: A Scoping Review of a Unique Biomedical Waste

Gamilah Al-Qadhi,  Sarah Al-Rai,  Layla Hafed, 
  • First Published: 10 February 2021
Research Article
Open Access

Chaetocin Promotes Osteogenic Differentiation via Modulating Wnt/Beta-Catenin Signaling in Mesenchymal Stem Cells

Youde Liang,  Xin Liu,  Ruiping Zhou,  Dawei Song,  Yi-Zhou Jiang,  Weiwei Xue, 
  • First Published: 09 February 2021
Research Article
Open Access

Graphene Oxide Quantum Dots Promote Osteogenic Differentiation of Stem Cells from Human Exfoliated Deciduous Teeth via the Wnt/β-Catenin Signaling Pathway

Xin Yang,  Qi Zhao,  JingWen Chen,  Jiayue Liu,  Jiacheng Lin,  Jiaxuan Lu,  Wenqing Li,  Dongsheng Yu,  Wei Zhao, 
  • First Published: 09 February 2021
Research Article
Open Access

Age-Related Macular Degeneration (AMD) Transmitochondrial Cybrids Protected from Cellular Damage and Death by Human Retinal Progenitor Cells (hRPCs)

Jeffrey J. Yu,  Daniel B. Azzam,  Marilyn Chwa,  Kevin Schneider,  Jang-Hyeon Cho,  Chinhui Hsiang,  Henry Klassen,  M. Cristina Kenney,  Jing Yang, 
  • First Published: 09 February 2021
Review Article
Open Access

Myogenic Differentiation of Stem Cells for Skeletal Muscle Regeneration

Dengjie Yu,  Zijun Cai,  Daishi Li,  Yi Zhang,  Miao He,  Yuntao Yang,  Di Liu,  Wenqing Xie,  Yusheng Li,  Wenfeng Xiao, 
  • First Published: 08 February 2021
Research Article
Open Access

Discovery of a Novel Long Noncoding RNA Lx8-SINE B2 as a Marker of Pluripotency

Fuquan Chen,  Miao Zhang,  Xiao Feng,  Xiaomin Li,  Haotian Sun,  Xinyi Lu, 
  • First Published: 08 February 2021
Review Article
Open Access

Advance in the Role of Epigenetic Reprogramming in Somatic Cell Nuclear Transfer-Mediated Embryonic Development

Xiaolei Zhang,  Shaorong Gao,  Xiaoyu Liu, 
  • First Published: 05 February 2021
Review Article
Open Access

Chromatin Regulation in Development: Current Understanding and Approaches

Zi Hao Zheng,  Tsz Wing Sam,  YingYing Zeng,  Justin Jang Hann Chu,  Yuin-Han Loh, 
  • First Published: 02 February 2021
Research Article
Open Access

Rapamycin Treatment of Tendon Stem/Progenitor Cells Reduces Cellular Senescence by Upregulating Autophagy

Daibang Nie,  Jianying Zhang,  Yiqin Zhou,  Jiuyi Sun,  Wang Wang,  James H.-C. Wang, 
  • First Published: 01 February 2021
Editorial
Open Access

Translating Stem Cell-Based Regenerative Approaches into Clinical Therapies for Musculoskeletal Tissue Repair

Arianna B. Lovati,  Bruna Corradetti,  Roberto Narcisi, 
  • First Published: 30 January 2021
Research Article
Open Access

Eif2s3y Promotes the Proliferation of Spermatogonial Stem Cells by Activating ERK Signaling

Mengfei Zhang,  Na Li,  Wenqing Liu,  Xiaomin Du,  Yudong Wei,  Donghui Yang,  Zhe Zhou,  Fanglin Ma,  Sha Peng,  Shiqiang Zhang,  Xin He,  Chunling Bai,  Guangpeng Li,  Jinlian Hua, 
  • First Published: 30 January 2021
Research Article
Open Access

Primary Cilia as a Biomarker in Mesenchymal Stem Cells Senescence: Influencing Osteoblastic Differentiation Potency Associated with Hedgehog Signaling Regulation

Su Fu,  Chunlin Zhang,  Xu Yan,  Dongzhe Li,  Yongkui Wang,  Chao Dong,  Zhengming Cao,  Yongming Ning,  Chenglong Shao,  Tengyue Yang, 
  • First Published: 27 January 2021
Research Article
Open Access

Multifaceted Optimization of MSC-Based Formulation upon Sodium Iodoacetate-Induced Osteoarthritis Models by Combining Advantageous HA/PG Hydrogel and Fluorescent Tracer

Ai-tong Wang,  Meng Zhao,  Ying Feng,  Honghong Jia,  Leisheng Zhang,  Hao Yu,  Zongjin Li,  Zhibo Han,  Zhongchao Han, 
  • First Published: 23 January 2021
Research Article
Open Access

Therapeutic Effects of Conditioned Medium of Neural Differentiated Human Bone Marrow-Derived Stem Cells on Rotenone-Induced Alpha-Synuclein Aggregation and Apoptosis

Mahesh Ramalingam,  Sujeong Jang,  Han-Seong Jeong, 
  • First Published: 23 January 2021
Review Article
Open Access

Exosome-Derived Noncoding RNAs as a Promising Treatment of Bone Regeneration

Bei Yin,  Qingge Ma,  Chenghao Song,  Lingyi Zhao,  Fanyuan Yu,  Chenglin Wang,  Yu Shi,  Ling Ye, 
  • First Published: 21 January 2021
Review Article
Open Access

The Application of Bioreactors for Cartilage Tissue Engineering: Advances, Limitations, and Future Perspectives

Liwei Fu,  Pinxue Li,  Hao Li,  Cangjian Gao,  Zhen Yang,  Tianyuan Zhao,  Wei Chen,  Zhiyao Liao,  Yu Peng,  Fuyang Cao,  Xiang Sui,  Shuyun Liu,  Quanyi Guo, 
  • First Published: 21 January 2021
Research Article
Open Access

Pluripotency of Dental Pulp Cells and Periodontal Ligament Cells Was Enhanced through Cell-Cell Communication via STAT3/Oct-4/Sox2 Signaling

Zhengjun Peng,  Lu Liu,  Wenyu Zhang,  Xi Wei, 
  • First Published: 20 January 2021
Research Article
Open Access

Stem Cells from Human Exfoliated Deciduous Teeth Attenuate Trigeminal Neuralgia in Rats

Xiaofeng Bai,  Xuedi Zhang,  Chun Wang,  Yao Liu,  Xuemei Liu,  Yu Fan,  Xia Zhang, 
  • First Published: 18 January 2021
Research Article
Open Access

Nsd2 Represses Endogenous Retrovirus MERVL in Embryonic Stem Cells

Tingting Gao,  Fuquan Chen,  Wenying Zhang,  Xuan Zhao,  Xiao Hu,  Xinyi Lu, 
  • First Published: 18 January 2021
Research Article
Open Access

IL-1 Receptor Antagonist Protects the Osteogenesis Capability of Gingival-Derived Stem/Progenitor Cells under Inflammatory Microenvironment Induced by Porphyromonas gingivalis Lipopolysaccharides

Yuxin Zhao,  Bobo Cai,  Weijun Zhu,  Jue Shi,  Yu Wang,  Misi Si, 
  • First Published: 18 January 2021
Research Article
Open Access

Effect of Stem Cell-Derived Extracellular Vesicles on Damaged Human Corneal Endothelial Cells

Raffaele Nuzzi,  Lola Buono,  Simona Scalabrin,  Marco De Iuliis,  Benedetta Bussolati, 
  • First Published: 18 January 2021
Review Article
Open Access

BAF Complex in Embryonic Stem Cells and Early Embryonic Development

Heyao Zhang,  Xuepeng Wang,  Jingsheng Li,  Ronghua Shi,  Ying Ye, 
  • First Published: 16 January 2021
Research Article
Open Access

Comparative Analysis of Tenogenic Gene Expression in Tenocyte-Derived Induced Pluripotent Stem Cells and Bone Marrow-Derived Mesenchymal Stem Cells in Response to Biochemical and Biomechanical Stimuli

Feikun Yang,  Dean W. Richardson, 
  • First Published: 15 January 2021
Review Article
Open Access

Advances in Female Germ Cell Induction from Pluripotent Stem Cells

Maisumu Gulimiheranmu,  Xinjie Wang,  Junmei Zhou, 
  • First Published: 15 January 2021
Review Article
Open Access

To Breathe or Not to Breathe: The Role of Oxygen in Bone Marrow-Derived Mesenchymal Stromal Cell Senescence

Dhir Niren Gala,  Zsolt Fabian, 
  • First Published: 13 January 2021
Research Article
Open Access

Mesenchymal Stem Cells Enhance Therapeutic Effect and Prevent Adverse Gastrointestinal Reaction of Methotrexate Treatment in Collagen-Induced Arthritis

Qiming Zhai,  Jiayi Dong,  Xuesi Zhang,  Xiaoning He,  Dongdong Fei,  Yan Jin,  Bei Li,  Fang Jin, 
  • First Published: 11 January 2021
Review Article
Open Access

Enteropathogenic Infections: Organoids Go Bacterial

Viktoria Hentschel,  Frank Arnold,  Thomas Seufferlein,  Ninel Azoitei,  Alexander Kleger,  Martin Müller, 
  • First Published: 08 January 2021
Research Article
Open Access

Reestablishment of Redox Homeostasis in the Nociceptive Primary Afferent as a Mechanism of Antinociception Promoted by Mesenchymal Stem/Stromal Cells in Oxaliplatin-Induced Chronic Peripheral Neuropathy

Anna Lethicia L. Oliveira,  Gisele G. L. Santos,  Renan F. Espirito-Santo,  Gessica Sabrina A. Silva,  Afrânio F. Evangelista,  Daniela N. Silva,  Milena B. P. Soares,  Cristiane Flora Villarreal, 
  • First Published: 07 January 2021
Review Article
Open Access

An Update on the Potential of Mesenchymal Stem Cell Therapy for Cutaneous Diseases

Yanyun Li,  Ziyu Ye,  Weiqin Yang,  Qunzhou Zhang,  Jincheng Zeng, 
  • First Published: 06 January 2021
Research Article
Open Access

Immunohistochemical Analysis of Histone H3 Modification in Newt Tail Tissue Cells following Amputation

Ji-Wen Wu,  Xu Zhang,  Reiko Sekiya,  Kiyoshi Aoyagi,  Tao-Sheng Li, 
  • First Published: 06 January 2021
Research Article
Open Access

Metformin-Induced MicroRNA-34a-3p Downregulation Alleviates Senescence in Human Dental Pulp Stem Cells by Targeting CAB39 through the AMPK/mTOR Signaling Pathway

Shuo Zhang,  Rong Zhang,  Pengyan Qiao,  Xiaocao Ma,  Rongjian Lu,  Feifan Wang,  Chuanjie Li,  Lingling E,  Hongchen Liu, 
  • First Published: 06 January 2021
Review Article
Open Access

Proteolytic Processing of CD44 and Its Implications in Cancer

Priscila Anhel Medrano-González,  Osmar Rivera-Ramírez,  Luis Felipe Montaño,  Erika P. Rendón-Huerta, 
  • First Published: 06 January 2021
Research Article
Open Access

Combined Use of Chitosan and Olfactory Mucosa Mesenchymal Stem/Stromal Cells to Promote Peripheral Nerve Regeneration In Vivo

Rui D. Alvites,  Mariana V. Branquinho,  Ana C. Sousa,  Irina Amorim,  Rui Magalhães,  Filipa João,  Diogo Almeida,  Sandra Amado,  Justina Prada,  Isabel Pires,  Federica Zen,  Stefania Raimondo,  Ana L. Luís,  Stefano Geuna,  Artur S. P. Varejão,  Ana C. Maurício, 
  • First Published: 04 January 2021