• Issue

    Exploration: Volume 2, Issue 6

    December 2022

FRONT COVER

Open Access

Front Cover: Active-ion-gated room temperature acetone gas sensing of ZnO nanowires array (EXP2 6/2022)

  • First Published: 18 December 2022
Front Cover: Active-ion-gated room temperature acetone gas sensing of ZnO nanowires array (EXP2 6/2022) Volume 2 Issue 6, 2022

Gang Cheng and co-workers firstly report an active-ion-gated strategy to active room temperature (RT) acetone sensing of metal oxide semiconductors (MOS). The strategy presents high performance and low power consumption, which paves the way for boosting the RT gas sensing performance of traditional MOS by customizing specific ions with various discharge gas atmosphere.

BACK COVER

Open Access

Back Cover: Atomic cerium modulated palladium nanoclusters exsolved ferrite catalysts for lean methane conversion (EXP2 6/2022)

  • First Published: 18 December 2022
Back Cover: Atomic cerium modulated palladium nanoclusters exsolved ferrite catalysts for lean methane conversion (EXP2 6/2022) Volume 2 Issue 6, 2022

The efficient conversion of CH4 is of great environmental and industrial significance. N2 as an optimal activation agent to develop a Pd nanocluster exsolved Ce-incorporated perovskite ferrite catalyst toward lean methane oxidation. The isolated Ce at the A-site of perovskite facilitates the thermodynamic and kinetics of the Pd exsolution process, lowering the Pd nanocluster formation temperature and promoting its quantity.

FRONTISPIECE

Open Access

Frontispiece: Electroshock synthesis of a bifunctional nonprecious multi-element alloy for alkaline hydrogen oxidation and evolution (EXP2 6/2022)

  • First Published: 18 December 2022
Frontispiece: Electroshock synthesis of a bifunctional nonprecious multi-element alloy for alkaline hydrogen oxidation and evolution (EXP2 6/2022) Volume 2 Issue 6, 2022

A facile electric shock method was used to synthesize an efficient, stable and inexpensive NiCoCuMoW bifunctional alloy electrocatalyst for both hydrogen oxidation and evolution. Density functional theory calculations and electrochemical experiments reveal that the multi-component synergy and plentiful active sites render the NiCoCuMoW superior electrocatalytic performance, rivalling the Pt/C benchmark catalysts.

ISSUE INFORMATION

Open Access

Issue Information

  • First Published: 18 December 2022

PERSPECTIVE

Open Access

Keeping up with the COVID's—Could siRNA-based antivirals be a part of the answer?

  • First Published: 14 July 2022
Keeping up with the COVID's—Could siRNA-based antivirals be a part of the answer?

COVID-19 is a highly contagious viral disease that has claimed the lives of millions of people worldwide. The virus continues to evolve, and each time it does, there is a greater risk that the vaccines and antivirals initially developed to target this deadly infection will no longer be therapeutically viable. Here we discuss the vaccines and the latest antiviral treatment strategies that are under investigation. In particular, we discuss siRNA and why it could be an important piece of the puzzle in the ongoing fight against COVID-19.

REVIEWS

Open Access

Advances in metal graphitic nanocapsules for biomedicine

  • First Published: 15 March 2022
Advances in metal graphitic nanocapsules for biomedicine

In this review, we summary the preparation, classification, and properties of versatile metal graphitic nanocapsules, and then introduce the recent progress of their applications in biodetection, bioimaging, and therapy in detail. In addition, challenges and their development prospects in biomedicine are also discussed. We expect the metal graphitic nanocapsules will advance the development of future clinical biomedicine.

Open Access

mRNA nanomedicine: Design and recent applications

  • First Published: 19 September 2022
mRNA nanomedicine: Design and recent applications

mRNA nanomedicines have shown considerable promise as prophylactic and therapeutic agents given their capacity to enable the in situ production of any protein. In this review, we discuss the design of nanoparticle-based platforms for mRNA delivery, as well as their recent application to viral infections, cancers, and genetic diseases.

Open Access

Stimuli-responsive crosslinked nanomedicine for cancer treatment

  • First Published: 21 April 2022
Stimuli-responsive crosslinked nanomedicine for cancer treatment

We classify the stimuli-responsive crosslinked nanomedicines (SCNs) into three categories based on the crosslinking strategies, including built-in, on-surface, and inter-particle crosslinking nanomedicines. These SCNs can respond to particular tumoral stimuli and go through a series of dynamic changes to circumvent different biological barriers, and subsequently improve anti-cancer efficacy and imaging sensitivity and specificity.

Open Access

Role of bioaerosol in virus transmission and material-based countermeasures

  • First Published: 23 May 2022
Role of bioaerosol in virus transmission and material-based countermeasures

Virus dissemination through droplets or aerosols is a predominant transmission mode of respiratory infections. This review summarizes direct and indirect mechanisms of aerosol generation with an emphasis on infection risks presented by the resuspension of settled droplets. Material-based approaches, including nanotechnology, to contain bioaerosol-mediated virus transmission are highlighted in this review.

Open Access

Advances in upconversion luminescence nanomaterial-based biosensor for virus diagnosis

  • First Published: 12 October 2022
Advances in upconversion luminescence nanomaterial-based biosensor for virus diagnosis

This review discusses the recent advancement in the upconversion nanoparticle (UCNP)-based biosensors for virus and biomarkers detection. We summarize four basic principles that guide the design of UCNP-based biosensors, which are utilized with luminescent or electric responses as output signals. Relative strategies with a detailed discussion are presented, and we suggest routes for progress in the field.

Open Access

Recent applications of immunomodulatory biomaterials for disease immunotherapy

  • First Published: 23 May 2022
Recent applications of immunomodulatory biomaterials for disease immunotherapy

Understanding the immunomodulatory functions of biomaterials themselves is critical for developing safe and effective immunotherapeutic platforms. This review summarizes some representative biomaterials with immunomodulatory functions discovered in recent years and their applications in therapy for inflammation, tumor, and autoimmune diseases, and discusses the challenges for the future development of biomaterials.

RESEARCH ARTICLES

Open Access

Gd2O3/b-TiO2 composite nanoprobes with ultra-high photoconversion efficiency for MR image-guided NIR-II photothermal therapy

  • First Published: 13 June 2022
Gd2O3/b-TiO2 composite nanoprobes with ultra-high photoconversion efficiency for MR image-guided NIR-II photothermal therapy

Low photoconversion efficiency and limited tissue penetration are the major barriers for photothermal therapy (PTT) agent application. Here, an efficient organic/inorganic dual-PTT agent guided by MRI was proposed. It is proved the oxygen vacancy band narrowed its band gap that led to NIR-II region absorb. Furthermore, the defect energy level trapping carrier and conjugate synergistic heat generation result in high photoconversion efficiency.

Open Access

Active-ion-gated room temperature acetone gas sensing of ZnO nanowires array

  • First Published: 14 October 2022
Active-ion-gated room temperature acetone gas sensing of ZnO nanowires array

This paper demonstrates a novel active-ion-gated strategy to active the room temperature (RT) gas sensing performance of ZnO NWs by self-powered triboelectric plasma system in ambient environment. The activated ZnO NWs shows considerable sensitivity, excellent selectivity, and rapid response to acetone gas at RT with maximum power consumption only 4.5 mW.

Open Access

Atomic cerium modulated palladium nanoclusters exsolved ferrite catalysts for lean methane conversion

  • First Published: 11 July 2022
Atomic cerium modulated palladium nanoclusters exsolved ferrite catalysts for lean methane conversion

The CH4 conversion is of great environmental and industrial significance to solve the greenhouse effect. N2 as an optimal activation agent to develop a Pd nanocluster exsolved Ce-incorporated perovskite ferrite catalyst toward lean methane oxidation. The isolated Ce locating at the A-site of perovskite framework facilitates the thermodynamic and kinetics of the Pd exsolution process, lowering the Pd nanocluster formation temperature and promoting its quantity.

Open Access

Electroshock synthesis of a bifunctional nonprecious multi-element alloy for alkaline hydrogen oxidation and evolution

  • First Published: 24 November 2022
Electroshock synthesis of a bifunctional nonprecious multi-element alloy for alkaline hydrogen oxidation and evolution

A facile electric shock method is used to synthesize an efficient, stable, and inexpensive NiCoCuMoW bifunctional alloy electrocatalyst for both hydrogen oxidation reaction (HOR) and hydrogen evolution reaction (HER). Combined experiments and theory calculations reveal that the multi-component synergy of different elements and plentiful active sites render the NiCoCuMoW superior HOR/HER performance, rivaling the Pt/C benchmark and most reported nonprecious catalysts.

Open Access

NIR light-propelled bullet-shaped carbon hollow nanomotors with controllable shell thickness for the enhanced dye removal

  • First Published: 18 November 2022
NIR light-propelled bullet-shaped carbon hollow nanomotors with controllable shell thickness for the enhanced dye removal

This work describes the construction of bullet-shaped carbon hollow particles with controllable shell thicknesses by heterogeneous interface growth on hard template. As a near infrared light-propelled nanomotor, it shows higher diffusion coefficient and faster velocity by self-thermophoresis for the enhanced dye removal.