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Review Article
Open Access

The Role of Stress-Induced O-GlcNAc Protein Modification in the Regulation of Membrane Transport

Viktória Fisi,  Attila Miseta,  Tamás Nagy, 
  • First Published: 31 December 2017
Research Article
Open Access

Idh2 Deficiency Exacerbates Acrolein-Induced Lung Injury through Mitochondrial Redox Environment Deterioration

Jung Hyun Park,  Hyeong Jun Ku,  Jin Hyup Lee,  Jeen-Woo Park, 
  • First Published: 31 December 2017
Research Article
Open Access

Antroquinonol Exerts Immunosuppressive Effect on CD8+ T Cell Proliferation and Activation to Resist Depigmentation Induced by H2O2

Cuiping Guan,  Qingtian Li,  Xiuzu Song,  Wen Xu,  Liuyu Li,  Aie Xu, 
  • First Published: 31 December 2017

Research Article
Open Access

Hederagenin Induces Apoptosis in Cisplatin-Resistant Head and Neck Cancer Cells by Inhibiting the Nrf2-ARE Antioxidant Pathway

Eun Hye Kim,  Seungho Baek,  Daiha Shin,  Jaewang Lee,  Jong-Lyel Roh, 
  • First Published: 31 December 2017
Review Article
Open Access

Protein Glutathionylation in the Pathogenesis of Neurodegenerative Diseases

Sun Joo Cha,  Hayoung Kim,  Hyun-Jun Choi,  Sanghyun Lee,  Kiyoung Kim, 
  • First Published: 31 December 2017
Research Article
Open Access

Comparison of Selected Parameters of Redox Homeostasis in Patients with Ataxia-Telangiectasia and Nijmegen Breakage Syndrome

Barbara Pietrucha,  Edyta Heropolitanska-Pliszka,  Mateusz Maciejczyk,  Halina Car,  Jolanta Sawicka-Powierza,  Radosław Motkowski,  Joanna Karpinska,  Marta Hryniewicka,  Anna Zalewska,  Malgorzata Pac,  Beata Wolska-Kusnierz,  Ewa Bernatowska,  Bozena Mikoluc, 
  • First Published: 31 December 2017
Corrigendum
Open Access

Corrigendum to “Resolving Contributions of Oxygen-Consuming and ROS-Generating Enzymes at the Synapse”

Engy A. Abdel-Rahman,  Ali M. Mahmoud,  Abdalla G. Alia,  Yasmine Radwan,  Basma Yasseen,  Abdelrahman AlOkda,  Ahmed Atwa,  Eslam Elhanafy,  Moaaz Habashy,  Sameh S. Ali, 
  • First Published: 28 December 2017

Review Article
Open Access

Fe-S Clusters Emerging as Targets of Therapeutic Drugs

Laurence Vernis,  Nadine El Banna,  Dorothée Baïlle,  Elie Hatem,  Amélie Heneman,  Meng-Er Huang, 
  • First Published: 28 December 2017
Review Article
Open Access

Oxidative Stress in Patients Undergoing Peritoneal Dialysis: A Current Review of the Literature

Vassilios Liakopoulos,  Stefanos Roumeliotis,  Xenia Gorny,  Theodoros Eleftheriadis,  Peter R. Mertens, 
  • First Published: 27 December 2017
Review Article
Open Access

Supplementation of Micronutrient Selenium in Metabolic Diseases: Its Role as an Antioxidant

Ning Wang,  Hor-Yue Tan,  Sha Li,  Yu Xu,  Wei Guo,  Yibin Feng, 
  • First Published: 26 December 2017
Research Article
Open Access

Experimental and Clinical Applications of Chamaecyparis obtusa Extracts in Dry Eye Disease

Lian Cui,  Hyo Seok Lee,  Ying Li,  Joo-Hee Choi,  Je-Jung Yun,  Ji Eun Jung,  Won Choi,  Kyung Chul Yoon, 
  • First Published: 26 December 2017
Research Article
Open Access

Capsaicin Protects Cardiomyocytes against Anoxia/Reoxygenation Injury via Preventing Mitochondrial Dysfunction Mediated by SIRT1

Huan He,  Yue Zhou,  Jiyi Huang,  Zelong Wu,  Zhangping Liao,  Dan Liu,  Dong Yin,  Ming He, 
  • First Published: 24 December 2017
Research Article
Open Access

RTA-408 Protects Kidney from Ischemia-Reperfusion Injury in Mice via Activating Nrf2 and Downstream GSH Biosynthesis Gene

Peng Han,  Zhiqiang Qin,  Jingyuan Tang,  Zhen Xu,  Ran Li,  Xuping Jiang,  Chengdi Yang,  Qianwei Xing,  Xiaokang Qi,  Min Tang,  Jiexiu Zhang,  Baixin Shen,  Wei Wang,  Chao Qin,  Wei Zhang, 
  • First Published: 24 December 2017
Research Article
Open Access

YiQiFuMai Powder Injection Protects against Ischemic Stroke via Inhibiting Neuronal Apoptosis and PKCδ/Drp1-Mediated Excessive Mitochondrial Fission

Yingqiong Xu,  Yan Wang,  Guangyun Wang,  Xinyi Ye,  Jiangwei Zhang,  Guosheng Cao,  Yazheng Zhao,  Zhen Gao,  Yuanyuan Zhang,  Boyang Yu,  Junping Kou, 
  • First Published: 24 December 2017
Review Article
Open Access

Omega Class Glutathione S-Transferase: Antioxidant Enzyme in Pathogenesis of Neurodegenerative Diseases

Youngjo Kim,  Sun Joo Cha,  Hyun-Jun Choi,  Kiyoung Kim, 
  • First Published: 24 December 2017
Research Article
Open Access

Oleic Acid and Hydroxytyrosol Inhibit Cholesterol and Fatty Acid Synthesis in C6 Glioma Cells

Paola Priore,  Antonio Gnoni,  Francesco Natali,  Mariangela Testini,  Gabriele V. Gnoni,  Luisa Siculella,  Fabrizio Damiano, 
  • First Published: 24 December 2017
Research Article
Open Access

Antioxidant and Hepatoprotective Activities of Polysaccharides from Spent Mushroom Substrates (Laetiporus sulphureus) in Acute Alcohol-Induced Mice

Huajie Zhao,  Yufei Lan,  Hui Liu,  Yongfa Zhu,  Weiru Liu,  Jianjun Zhang,  Le Jia, 
  • First Published: 21 December 2017
Research Article
Open Access

Impact of Hot Environment on Fluid and Electrolyte Imbalance, Renal Damage, Hemolysis, and Immune Activation Postmarathon

Rodrigo Assunção Oliveira,  Ana Paula Rennó Sierra,  Marino Benetti,  Nabil Ghorayeb,  Carlos A. Sierra,  Maria Augusta Peduti Dal Molin Kiss,  Maria Fernanda Cury-Boaventura, 
  • First Published: 21 December 2017
Clinical Study
Open Access

Absorption and Elimination of Oat Avenanthramides in Humans after Acute Consumption of Oat Cookies

Tianou Zhang,  Jing Shao,  Yike Gao,  Chi Chen,  Dan Yao,  Yi Fang Chu,  Jodee Johnson,  Chounghun Kang,  Dongwook Yeo,  Li Li Ji, 
  • First Published: 21 December 2017
Research Article
Open Access

A Carotenoid Extract from a Southern Italian Cultivar of Pumpkin Triggers Nonprotective Autophagy in Malignant Cells

Maria Russo,  Stefania Moccia,  Stefania Bilotto,  Carmela Spagnuolo,  Miriana Durante,  Marcello Salvatore Lenucci,  Giovanni Mita,  Maria Grazia Volpe,  Rita Patrizia Aquino,  Gian Luigi Russo, 
  • First Published: 21 December 2017
Review Article
Open Access

Possible Mechanisms of Mercury Toxicity and Cancer Promotion: Involvement of Gap Junction Intercellular Communications and Inflammatory Cytokines

Roberto Zefferino,  Claudia Piccoli,  Nunzia Ricciardi,  Rosella Scrima,  Nazzareno Capitanio, 
  • First Published: 21 December 2017
Review Article
Open Access

NADPH Oxidase Deficiency: A Multisystem Approach

Giuliana Giardino,  Maria Pia Cicalese,  Ottavia Delmonte,  Maddalena Migliavacca,  Boaz Palterer,  Lorenzo Loffredo,  Emilia Cirillo,  Vera Gallo,  Francesco Violi,  Claudio Pignata, 
  • First Published: 21 December 2017
Review Article
Open Access

Unfolded Protein Response of the Endoplasmic Reticulum in Tumor Progression and Immunogenicity

Yoon Seon Yoo,  Hye Gyeong Han,  Young Joo Jeon, 
  • First Published: 21 December 2017
Review Article
Open Access

Ginsenoside Rb1 for Myocardial Ischemia/Reperfusion Injury: Preclinical Evidence and Possible Mechanisms

Qun Zheng,  Xiao-Yi Bao,  Peng-Chong Zhu,  Qiang Tong,  Guo-Qing Zheng,  Yan Wang, 
  • First Published: 21 December 2017
Research Article
Open Access

Insulin-Like Growth Factor (IGF) Binding Protein-2, Independently of IGF-1, Induces GLUT-4 Translocation and Glucose Uptake in 3T3-L1 Adipocytes

Biruhalem Assefa,  Ayman M. Mahmoud,  Andreas F. H. Pfeiffer,  Andreas L. Birkenfeld,  Joachim Spranger,  Ayman M. Arafat, 
  • First Published: 20 December 2017
Research Article
Open Access

Radical Scavenger Capacity of Jabuticaba Fruit (Myrciaria cauliflora) and Its Biological Effects in Hypertensive Rats

Camila Gabriela de Souza,  Daniela Medeiros Lobo de Andrade,  Juliana Bahia Reis Jordão,  Renato Ivan de Ávila,  Leonardo Luiz Borges,  Boniek Gontijo Vaz,  Marize Campos Valadares,  Eric de Souza Gil,  Edemilson Cardoso da Conceição,  Matheus Lavorenti Rocha, 
  • First Published: 20 December 2017
Research Article
Open Access

Phagocytosis of Advanced Glycation End Products (AGEs) in Macrophages Induces Cell Apoptosis

Yuan Gao,  Hidenori Wake,  Yuta Morioka,  Keyue Liu,  Kiyoshi Teshigawara,  Megumi Shibuya,  Jingxiu Zhou,  Shuji Mori,  Hideo Takahashi,  Masahiro Nishibori, 
  • First Published: 20 December 2017
Research Article
Open Access

Differential Susceptibility of Germ and Leydig Cells to Cadmium-Mediated Toxicity: Impact on Testis Structure, Adiponectin Levels, and Steroidogenesis

Marli C. Cupertino,  Rômulo D. Novaes,  Eliziária C. Santos,  Ana C. Neves,  Edson Silva,  Juraci A. Oliveira,  Sérgio L. P. Matta, 
  • First Published: 20 December 2017
Review Article
Open Access

Antidepressant Flavonoids and Their Relationship with Oxidative Stress

Lucian Hritcu,  Radu Ionita,  Paula Alexandra Postu,  Girish Kumar Gupta,  Hasan Turkez,  Tamires Cardoso Lima,  Caroline Uchôa Souza Carvalho,  Damião Pergentino de Sousa, 
  • First Published: 19 December 2017
Research Article
Open Access

Chrysin Administration Protects against Oxidative Damage in Varicocele-Induced Adult Rats

Gabriela Missassi,  Cibele dos Santos Borges,  Josiane de Lima Rosa,  Patrícia Villela e Silva,  Airton da Cunha Martins Jr.,  Fernando Barbosa Jr.,  Wilma De Grava Kempinas, 
  • First Published: 19 December 2017
Research Article
Open Access

NRF2 Regulates HER1 Signaling Pathway to Modulate the Sensitivity of Ovarian Cancer Cells to Lapatinib and Erlotinib

Ibrahim H. Kankia,  Hilal S. Khalil,  Simon P. Langdon,  Peter R. Moult,  James L. Bown,  Yusuf Y. Deeni, 
  • First Published: 19 December 2017
Review Article
Open Access

The Crosstalk between ROS and Autophagy in the Field of Transplantation Medicine

Anne C. Van Erp,  Dane Hoeksma,  Rolando A. Rebolledo,  Petra J. Ottens,  Ina Jochmans,  Diethard Monbaliu,  Jacques Pirenne,  Henri G. D. Leuvenink,  Jean-Paul Decuypere, 
  • First Published: 19 December 2017
Research Article
Open Access

Vitamin D Receptor Activation Influences NADPH Oxidase (NOX2) Activity and Protects against Neurological Deficits and Apoptosis in a Rat Model of Traumatic Brain Injury

Changmeng Cui,  Sixin Song,  Jianzhong Cui,  Yan Feng,  Junling Gao,  Pei Jiang, 
  • First Published: 19 December 2017
Review Article
Open Access

Ischemic Retinopathies: Oxidative Stress and Inflammation

José Carlos Rivera,  Rabah Dabouz,  Baraa Noueihed,  Samy Omri,  Houda Tahiri,  Sylvain Chemtob, 
  • First Published: 19 December 2017
Research Article
Open Access

Cytotoxicity Study of Cyclopentapeptide Analogues of Marine Natural Product Galaxamide towards Human Breast Cancer Cells

Jignesh Lunagariya,  Xiaojian Liao,  Weili Long,  Shenghui Zhong,  Poonam Bhadja,  Hangbin Li,  Bingxin Zhao,  Shihai Xu, 
  • First Published: 19 December 2017
Research Article
Open Access

Change of the State of the Natural Antioxidant Barrier of a Body and Psychological Parameters in Patients Aged above 60

Katarzyna Porzych,  Beata Augustyńska,  Marcin Porzych,  Martyna Porzych,  Emilia Mikołajewska,  Daria Kupczyk,  Rafał Bilski,  Magdalena Żyła,  Mirosława Szark-Eckardt,  Kornelia Kędziora-Kornatowska, 
  • First Published: 19 December 2017
Research Article
Open Access

Differential Alterations of the Mitochondrial Morphology and Respiratory Chain Complexes during Postnatal Development of the Mouse Lung

Natalia El-Merhie,  Eveline Baumgart-Vogt,  Adrian Pilatz,  Susanne Pfreimer,  Bianca Pfeiffer,  Oleg Pak,  Djuro Kosanovic,  Michael Seimetz,  Ralph Theo Schermuly,  Norbert Weissmann,  Srikanth Karnati, 
  • First Published: 19 December 2017
Review Article
Open Access

How AMPK and PKA Interplay to Regulate Mitochondrial Function and Survival in Models of Ischemia and Diabetes

Jingdian Zhang,  Yumeng Wang,  Xiaofeng Liu,  Ruben K. Dagda,  Ying Zhang, 
  • First Published: 17 December 2017
Review Article
Open Access

The Interrelation between Reactive Oxygen Species and Autophagy in Neurological Disorders

Congcong Fang,  Lijuan Gu,  Daniel Smerin,  Shanping Mao,  Xiaoxing Xiong, 
  • First Published: 17 December 2017
Editorial
Open Access

Modulation of Oxidative Stress: Pharmaceutical and Pharmacological Aspects 2017

Luciano Saso,  Liudmila Korkina,  Neven Zarkovic, 
  • First Published: 17 December 2017
Research Article
Open Access

The Effect of On-Pump and Off-Pump Bypass Operations on Oxidative Damage and Antioxidant Parameters

Ayse Dogan,  Fevzi Sarper Turker, 
  • First Published: 17 December 2017
Research Article
Open Access

Roles of Endoplasmic Reticulum Stress in NECA-Induced Cardioprotection against Ischemia/Reperfusion Injury

Fengmei Xing,  Hui Han,  Yonggui He,  Yidong Zhang,  Liwei Jing,  Zhelong Xu,  Jinkun Xi, 
  • First Published: 17 December 2017
Research Article
Open Access

Exercise Training under Exposure to Low Levels of Fine Particulate Matter: Effects on Heart Oxidative Stress and Extra-to-Intracellular HSP70 Ratio

Aline Sfalcin Mai,  Analu Bender dos Santos,  Lílian Corrêa Costa Beber,  Renan Daniel Bueno Basso,  Lucas Machado Sulzbacher,  Pauline Brendler Goettems-Fiorin,  Matias Nunes Frizzo,  Claudia Ramos Rhoden,  Mirna Stela Ludwig,  Thiago Gomes Heck, 
  • First Published: 13 December 2017
Research Article
Open Access

Modulation of Multidrug Resistance Gene Expression by Coumarin Derivatives in Human Leukemic Cells

Tomasz Kubrak,  Anna Bogucka-Kocka,  Łukasz Komsta,  Daniel Załuski,  Jacek Bogucki,  Dariusz Galkowski,  Robert Kaczmarczyk,  Marcin Feldo,  Maria Cioch,  Janusz Kocki, 
  • First Published: 13 December 2017
Review Article
Open Access

Opposing Effects of Oxygen Regulation on Kallistatin Expression: Kallistatin as a Novel Mediator of Oxygen-Induced HIF-1-eNOS-NO Pathway

Julie Chao,  Youming Guo,  Pengfei Li,  Lee Chao, 
  • First Published: 13 December 2017
Research Article
Open Access

Therapeutic Potential of Novel Twin Compounds Containing Tetramethylpyrazine and Carnitine Substructures in Experimental Ischemic Stroke

Ziying Wang,  Zhuanli Zhou,  Xinbing Wei,  Mingwei Wang,  Bi-Ou Wang,  Yanan Zhang,  Xiaoting He,  Yu Sun,  Xiaojie Wang,  Mingcheng Sun,  Yan Zhang,  Xiaowei Gong,  Fan Yi, 
  • First Published: 13 December 2017
Research Article
Open Access

The Effect of a Short-Term Exposure to Lead on the Levels of Essential Metal Ions, Selected Proteins Related to Them, and Oxidative Stress Parameters in Humans

Michał Dobrakowski,  Marta Boroń,  Ewa Birkner,  Aleksandra Kasperczyk,  Ewa Chwalińska,  Grażyna Lisowska,  Sławomir Kasperczyk, 
  • First Published: 13 December 2017
Clinical Study
Open Access

Low-Level Laser Irradiation Exerts Antiaggregative Effect on Human Platelets Independently on the Nitric Oxide Metabolism and Release of Platelet Activation Markers

Piotr Rola,  Adrian Doroszko,  Ewa Szahidewicz-Krupska,  Paweł Rola,  Piotr Dobrowolski,  Robert Skomro,  Alicja Szymczyszyn,  Grzegorz Mazur,  Arkadiusz Derkacz, 
  • First Published: 12 December 2017

Review Article
Open Access

Multifaceted Roles of GSK-3 in Cancer and Autophagy-Related Diseases

Romina Mancinelli,  Guido Carpino,  Simonetta Petrungaro,  Caterina Loredana Mammola,  Luana Tomaipitinca,  Antonio Filippini,  Antonio Facchiano,  Elio Ziparo,  Claudia Giampietri, 
  • First Published: 12 December 2017
Research Article
Open Access

Impaired Oxidative Status Is Strongly Associated with Cardiovascular Risk Factors

E. Brunelli,  D. La Russa,  D. Pellegrino, 
  • First Published: 12 December 2017
Research Article
Open Access

Cadmium-Induced Oxidative Stress Impairs Glycemic Control in Adolescents

Gabriele Pizzino,  Natasha Irrera,  Alessandra Bitto,  Giovanni Pallio,  Federica Mannino,  Vincenzo Arcoraci,  Federica Aliquò,  Letteria Minutoli,  Chiara De Ponte,  Paola D’andrea,  Francesco Squadrito,  Domenica Altavilla, 
  • First Published: 12 December 2017
Review Article
Open Access

Linking Cancer Cachexia-Induced Anabolic Resistance to Skeletal Muscle Oxidative Metabolism

Justin P. Hardee,  Ryan N. Montalvo,  James A. Carson, 
  • First Published: 11 December 2017
Research Article
Open Access

Xylopine Induces Oxidative Stress and Causes G2/M Phase Arrest, Triggering Caspase-Mediated Apoptosis by p53-Independent Pathway in HCT116 Cells

Luciano de Souza Santos,  Valdenizia Rodrigues Silva,  Leociley Rocha Alencar Menezes,  Milena Botelho Pereira Soares,  Emmanoel Vilaça Costa,  Daniel Pereira Bezerra, 
  • First Published: 06 December 2017
Clinical Study
Open Access

Effect of Vitamin D Receptor Activation on the AGE/RAGE System and Myeloperoxidase in Chronic Kidney Disease Patients

Claudia Torino,  Patrizia Pizzini,  Sebastiano Cutrupi,  Rocco Tripepi,  Antonio Vilasi,  Giovanni Tripepi,  Francesca Mallamaci,  Carmine Zoccali, 
  • First Published: 06 December 2017
Research Article
Open Access

Salidroside Inhibits HMGB1 Acetylation and Release through Upregulation of SirT1 during Inflammation

Zhilin Qi,  Yao Zhang,  Shimei Qi,  Liefeng Ling,  Lin Gui,  Liang Yan,  Jun Lv,  Qiang Li, 
  • First Published: 03 December 2017
Research Article
Open Access

Effect of Bioactive Compound of Aronia melanocarpa on Cardiovascular System in Experimental Hypertension

Martina Cebova,  Jana Klimentova,  Pavol Janega,  Olga Pechanova, 
  • First Published: 30 November 2017
Research Article
Open Access

Pomegranate Juice Prevents the Formation of Lung Nodules Secondary to Chronic Cigarette Smoke Exposure in an Animal Model

Ahmad Husari,  Yasmine Hashem,  Ghazi Zaatari,  Marwan El Sabban, 
  • First Published: 30 November 2017
Research Article
Open Access

Cytoprotective Effects of Cell-Permeable Bifunctional Antioxidant Enzyme, GST-TAT-SOD, against Cisplatin-Induced Cell Damage

Jianru Pan,  Lingling Li,  Lili Liang,  Huocong He,  Ying Su,  Xiangling Wang,  Shutao Liu, 
  • First Published: 30 November 2017
Research Article
Open Access

Lactonase Activity and Lipoprotein-Phospholipase A2 as Possible Novel Serum Biomarkers for the Differential Diagnosis of Autism Spectrum Disorders and Rett Syndrome: Results from a Pilot Study

Joussef Hayek,  Carlo Cervellati,  Ilaria Crivellari,  Alessandra Pecorelli,  Giuseppe Valacchi, 
  • First Published: 28 November 2017
Research Article
Open Access

Apocynin Prevents Abnormal Megakaryopoiesis and Platelet Activation Induced by Chronic Stress

Leonardo Sandrini,  Alessandro Ieraci,  Patrizia Amadio,  Maurizio Popoli,  Elena Tremoli,  Silvia S. Barbieri, 
  • First Published: 28 November 2017
Research Article
Open Access

Apoptotic Protease Activating Factor-1 Inhibitor Mitigates Myocardial Ischemia Injury via Disturbing Procaspase-9 Recruitment by Apaf-1

Ying Wang,  Qiuyan Zhang,  Liangjie Zhong,  Mingshen Lin,  Xiaoling Luo,  Siyu Liu,  Peng Xu,  Xinhua Liu,  Yi Zhun Zhu, 
  • First Published: 27 November 2017
Review Article
Open Access

The eIF4E2-Directed Hypoxic Cap-Dependent Translation Machinery Reveals Novel Therapeutic Potential for Cancer Treatment

Gaelan Melanson,  Sara Timpano,  James Uniacke, 
  • First Published: 26 November 2017
Review Article
Open Access

P-glycoprotein (ABCB1) and Oxidative Stress: Focus on Alzheimer’s Disease

Giulia Sita,  Patrizia Hrelia,  Andrea Tarozzi,  Fabiana Morroni, 
  • First Published: 26 November 2017
Review Article
Open Access

Polyphenols and Oxidative Stress in Atherosclerosis-Related Ischemic Heart Disease and Stroke

Yu-Chen Cheng,  Jer-Ming Sheen,  Wen Long Hu,  Yu-Chiang Hung, 
  • First Published: 26 November 2017
Review Article
Open Access

Chronic Kidney Disease and Disproportionally Increased Cardiovascular Damage: Does Oxidative Stress Explain the Burden?

Anila Duni,  Vassilios Liakopoulos,  Karolos-Pavlos Rapsomanikis,  Evangelia Dounousi, 
  • First Published: 23 November 2017
Review Article
Open Access

Markers and Biomarkers of Endothelium: When Something Is Rotten in the State

Nikolay V. Goncharov,  Alexander D. Nadeev,  Richard O. Jenkins,  Pavel V. Avdonin, 
  • First Published: 23 November 2017
Review Article
Open Access

The Significance of Hypothiocyanite Production via the Pendrin/DUOX/Peroxidase Pathway in the Pathogenesis of Asthma

Kenji Izuhara,  Shoichi Suzuki,  Masahiro Ogawa,  Satoshi Nunomura,  Yasuhiro Nanri,  Yasutaka Mitamura,  Tomohito Yoshihara, 
  • First Published: 22 November 2017
Research Article
Open Access

Exercise Combined with Rhodiola sacra Supplementation Improves Exercise Capacity and Ameliorates Exhaustive Exercise-Induced Muscle Damage through Enhancement of Mitochondrial Quality Control

Yaoshan Dun,  Suixin Liu,  Wenliang Zhang,  Murong Xie,  Ling Qiu, 
  • First Published: 22 November 2017
Research Article
Open Access

Active Fragment of Veronica ciliata Fisch. Attenuates t-BHP-Induced Oxidative Stress Injury in HepG2 Cells through Antioxidant and Antiapoptosis Activities

Yiran Sun,  Qiuxia Lu,  Libo He,  Yueyue Shu,  Shiyan Zhang,  Shancai Tan,  Lin Tang, 
  • First Published: 22 November 2017
Research Article
Open Access

Modulatory Effect of Fermented Papaya Extracts on Mammary Gland Hyperplasia Induced by Estrogen and Progestin in Female Rats

Zhenqiang You,  Junying Sun,  Feng Xie,  Zhiqin Chen,  Sheng Zhang,  Hao Chen,  Fang Liu,  Lili Li,  Guocan Chen,  Yisheng Song,  Yaoxian Xuan,  Gaoli Zheng,  Yanfei Xin, 
  • First Published: 20 November 2017
Research Article
Open Access

Coenzyme Q10 Regulates Antioxidative Stress and Autophagy in Acute Myocardial Ischemia-Reperfusion Injury

Shao Liang,  Zhang Ping,  Jin Ge, 
  • First Published: 19 November 2017
Research Article
Open Access

Effects of Aging and Tocotrienol-Rich Fraction Supplementation on Brain Arginine Metabolism in Rats

Musalmah Mazlan,  Hamizah Shahirah Hamezah,  Nursiati Mohd Taridi,  Yu Jing,  Ping Liu,  Hu Zhang,  Wan Zurinah Wan Ngah,  Hanafi Ahmad Damanhuri, 
  • First Published: 19 November 2017
Editorial
Open Access

New Insights into the Benefits of Polyphenols in Chronic Diseases

A. Tresserra-Rimbau,  S. Arranz,  A. Vallverdu-Queralt, 
  • First Published: 19 November 2017
Research Article
Open Access

Solid Lipid Curcumin Particles Induce More DNA Fragmentation and Cell Death in Cultured Human Glioblastoma Cells than Does Natural Curcumin

Panchanan Maiti,  Abeer Al-Gharaibeh,  Nivya Kolli,  Gary L. Dunbar, 
  • First Published: 19 November 2017
Research Article
Open Access

Salusin-β Is Involved in Diabetes Mellitus-Induced Endothelial Dysfunction via Degradation of Peroxisome Proliferator-Activated Receptor Gamma

Hai-Jian Sun,  Dan Chen,  Pei-Yao Wang,  Ming-Yu Wan,  Chen-Xing Zhang,  Zhi-Xuan Zhang,  Wei Lin,  Feng Zhang, 
  • First Published: 19 November 2017
Clinical Study
Open Access

The Role of Redox-Regulating Enzymes in Inoperable Breast Cancers Treated with Neoadjuvant Chemotherapy

Nelli Roininen,  Kirsi-Maria Haapasaari,  Peeter Karihtala, 
  • First Published: 19 November 2017
Editorial
Open Access

Oxidative Stress in Metabolic Disorders and Drug-Induced Injury: The Potential Role of Nrf2 and PPARs Activators

Ayman M. Mahmoud,  M. Yvonne Alexander,  Yusuf Tutar,  Fiona L. Wilkinson,  Alessandro Venditti, 
  • First Published: 19 November 2017
Research Article
Open Access

Pretreatment Donors after Circulatory Death with Simvastatin Alleviates Liver Ischemia Reperfusion Injury through a KLF2-Dependent Mechanism in Rat

Zhongzhong Liu,  Xingjian Zhang,  Qi Xiao,  Shaojun Ye,  Chin-Hui Lai,  Jun Luo,  Xiaoying Huang,  Wei Wang,  Cheng Zeng,  Zibiao Zhong,  Xiaoli Fan,  Zhiping Xia,  Yan Xiong,  Xinfang Mao,  Qifa Ye,  Yanfeng Wang, 
  • First Published: 19 November 2017
Review Article
Open Access

DNA Methylation and the Potential Role of Methyl-Containing Nutrients in Cardiovascular Diseases

Gang Liu,  Peng Bin,  Tianwei Wang,  Wenkai Ren,  Jin Zhong,  Jun Liang,  Chien-An Andy Hu,  Zhaoying Zeng,  Yulong Yin, 
  • First Published: 16 November 2017
Editorial
Open Access

Discovery and Biological Evaluation of Natural Phenolic Antioxidants

Jie Li,  Keyvan Dastmalchi,  Lin-sen Qing,  Pei Luo, 
  • First Published: 16 November 2017
Research Article
Open Access

Deficiency of the Purinergic Receptor 2X7 Attenuates Nonalcoholic Steatohepatitis Induced by High-Fat Diet: Possible Role of the NLRP3 Inflammasome

Claudia Blasetti Fantauzzi,  Stefano Menini,  Carla Iacobini,  Chiara Rossi,  Eleonora Santini,  Anna Solini,  Giuseppe Pugliese, 
  • First Published: 15 November 2017
Research Article
Open Access

The Natural Carotenoid Crocetin and the Synthetic Tellurium Compound AS101 Protect the Ovary against Cyclophosphamide by Modulating SIRT1 and Mitochondrial Markers

Giovanna Di Emidio,  Giulia Rossi,  Isabelle Bonomo,  Gonzalo Luis Alonso,  Roberta Sferra,  Antonella Vetuschi,  Paolo Giovanni Artini,  Alessandro Provenzani,  Stefano Falone,  Gaspare Carta,  Anna Maria D’Alessandro,  Fernanda Amicarelli,  Carla Tatone, 
  • First Published: 15 November 2017
Research Article
Open Access

Preclinical Antileukemia Activity of Tramesan: A Newly Identified Bioactive Fungal Metabolite

M. R. Ricciardi,  R. Licchetta,  S. Mirabilii,  M. Scarpari,  A. Parroni,  A. A. Fabbri,  P. Cescutti,  M. Reverberi,  C. Fanelli,  A. Tafuri, 
  • First Published: 15 November 2017
Research Article
Open Access

Zinc Protects Oxidative Stress-Induced RPE Death by Reducing Mitochondrial Damage and Preventing Lysosome Rupture

Dinusha Rajapakse,  Tim Curtis,  Mei Chen,  Heping Xu, 
  • First Published: 14 November 2017
Research Article
Open Access

Edaravone, a Synthetic Free Radical Scavenger, Enhances Alteplase-Mediated Thrombolysis

Kiyoshi Kikuchi,  Kentaro Setoyama,  Ko-ichi Kawahara,  Tomoka Nagasato,  Takuto Terashi,  Koki Ueda,  Kazuki Nakanishi,  Shotaro Otsuka,  Naoki Miura,  Hisayo Sameshima,  Kazuya Hosokawa,  Yoichiro Harada,  Binita Shrestha,  Mika Yamamoto,  Yoko Morimoto-Yamashita,  Haruna Kikuchi,  Ryoji Kiyama,  Chinatsu Kamikokuryo,  Salunya Tancharoen,  Harutoshi Sakakima,  Motohiro Morioka,  Eiichiro Tanaka,  Takashi Ito,  Ikuro Maruyama, 
  • First Published: 10 November 2017
Research Article
Open Access

Oxidative Stress-Related Parthanatos of Circulating Mononuclear Leukocytes in Heart Failure

Tamás Bárány,  Andrea Simon,  Gergő Szabó,  Rita Benkő,  Zsuzsanna Mezei,  Levente Molnár,  Dávid Becker,  Béla Merkely,  Endre Zima,  Eszter M. Horváth, 
  • First Published: 09 November 2017

Research Article
Open Access

Cultivation and Immortalization of Human B-Cells Producing a Human Monoclonal IgM Antibody Binding to MDA-LDL: Further Evidence for Formation of Atherogenic MDA-LDL Adducts in Humans In Vivo

Franz Tatzber,  Edith Pursch,  Ulrike Resch,  Roswitha Pfragner,  Sandra Holasek,  Meinrad Lindschinger,  Gerhard Cvirn,  Willibald Wonisch, 
  • First Published: 09 November 2017
Editorial
Open Access

Antioxidant Phytochemicals at the Pharma-Nutrition Interface

Elena Azzini,  Jasminka Giacometti,  Gian Luigi Russo, 
  • First Published: 08 November 2017
Review Article
Open Access

Regulation of Sirtuin-Mediated Protein Deacetylation by Cardioprotective Phytochemicals

Niria Treviño-Saldaña,  Gerardo García-Rivas, 
  • First Published: 06 November 2017
Research Article
Open Access

The Role of Oxidative Stress in Decreased Acetylcholinesterase Activity at the Neuromuscular Junction of the Diaphragm during Sepsis

Hua Liu,  Jin Wu,  Jun-yan Yao,  Hong Wang,  Shi-tong Li, 
  • First Published: 05 November 2017
Research Article
Open Access

Activation of NLRP3 Inflammasome by Advanced Glycation End Products Promotes Pancreatic Islet Damage

Xiang Kong,  Ai-Ling Lu,  Xin-Ming Yao,  Qiang Hua,  Xiao-Yong Li,  Li Qin,  Hong-Mei Zhang,  Guang-Xun Meng,  Qing Su, 
  • First Published: 05 November 2017
Research Article
Open Access

Extracellular Vesicles from Adipose-Derived Mesenchymal Stem Cells Downregulate Senescence Features in Osteoarthritic Osteoblasts

Miguel Tofiño-Vian,  Maria Isabel Guillén,  María Dolores Pérez del Caz,  Miguel Angel Castejón,  Maria José Alcaraz, 
  • First Published: 05 November 2017
Research Article
Open Access

An Alginate/Cyclodextrin Spray Drying Matrix to Improve Shelf Life and Antioxidant Efficiency of a Blood Orange By-Product Extract Rich in Polyphenols: MMPs Inhibition and Antiglycation Activity in Dysmetabolic Diseases

Maria Rosaria Lauro,  Lucia Crascì,  Virgilio Giannone,  Gabriele Ballistreri,  Simona Fabroni,  Francesca Sansone,  Paolo Rapisarda,  Anna Maria Panico,  Giovanni Puglisi, 
  • First Published: 02 November 2017
Letter to the Editor
Open Access

Comment on “A Preclinical Systematic Review of Ginsenoside-Rg1 in Experimental Parkinson’s Disease”

Yi-bo He,  Yong-lin Liu,  Yi-min Chen, 
  • First Published: 01 November 2017

Review Article
Open Access

Cellular Senescence in Age-Related Macular Degeneration: Can Autophagy and DNA Damage Response Play a Role?

Janusz Blasiak,  Malgorzata Piechota,  Elzbieta Pawlowska,  Magdalena Szatkowska,  Ewa Sikora,  Kai Kaarniranta, 
  • First Published: 01 November 2017
Research Article
Open Access

Low Glucose Concentrations Induce a Similar Inflammatory Response in Monocytes from Type 2 Diabetic Patients and Healthy Subjects

Francesco Piarulli,  Giovanni Sartore,  Annalisa Sechi,  Daniela Basso,  Paola Fogar,  Eliana Greco,  Eugenio Ragazzi,  Annunziata Lapolla, 
  • First Published: 31 October 2017
Research Article
Open Access

Effects of White Wine Consumption on Weight in Rats: Do Polyphenols Matter?

Ana Marija Milat,  Ivana Mudnić,  Ivica Grković,  Nikola Ključević,  Mia Grga,  Iva Jerčić,  Diana Jurić,  Danica Ivanković,  Benjamin Benzon,  Mladen Boban, 
  • First Published: 31 October 2017
Editorial
Open Access

MicroRNA Regulation of Oxidative Stress

Jaideep Banerjee,  Savita Khanna,  Akash Bhattacharya, 
  • First Published: 31 October 2017
Research Article
Open Access

Probucol Protects Rats from Cardiac Dysfunction Induced by Oxidative Stress following Cardiopulmonary Resuscitation

Xu Xiao,  Huiyuan Hou,  Victor Lin,  Daisy Ho,  Kyle Tran,  Briana Che,  Adam May,  Jiancheng Zhang,  Zhigang Lu,  Zhongping Lu,  Peter X. Shaw, 
  • First Published: 30 October 2017
Research Article
Open Access

Resveratrol Prevents ROS-Induced Apoptosis in High Glucose-Treated Retinal Capillary Endothelial Cells via the Activation of AMPK/Sirt1/PGC-1α Pathway

Jun Li,  Songping Yu,  Jia Ying,  Tianyan Shi,  Peipei Wang, 
  • First Published: 29 October 2017
Research Article
Open Access

Immediate Early Response Gene X-1 (IEX-1) Mediates Ischemic Preconditioning-Induced Cardioprotection in Rats

Ming-Jiang Xu,  Yan Cai,  Aijuan Qu,  John Y.-J. Shyy,  Wenjing Li,  Xian Wang, 
  • First Published: 29 October 2017
Editorial
Open Access

Oxidants and Redox Signaling: Perspectives in Cancer Therapy, Inflammation, and Plasma Medicine

Sander Bekeschus,  Lars Bräutigam,  Kristian Wende,  Eva-Maria Hanschmann, 
  • First Published: 29 October 2017
Research Article
Open Access

Echinacoside Alleviates UVB Irradiation-Mediated Skin Damage via Inhibition of Oxidative Stress, DNA Damage, and Apoptosis

Di Zhang,  Chengtao Lu,  Zhe Yu,  Xiayin Wang,  Li Yan,  Juanli Zhang,  Hua Li,  Jianbo Wang,  Aidong Wen, 
  • First Published: 26 October 2017
Research Article
Open Access

Spondias purpurea L. (Anacardiaceae): Antioxidant and Antiulcer Activities of the Leaf Hexane Extract

Cynthia Layse Ferreira de Almeida,  Samara Alves Brito,  Temístocles Italo de Santana,  Henrique Bandeira Alves Costa,  Carlson Helder Reis de Carvalho Júnior,  Márcia Vanusa da Silva,  Lécio Leone de Almeida,  Larissa Araújo Rolim,  Vanda Lucia dos Santos,  Almir Gonçalves Wanderley,  Teresinha Gonçalves da Silva, 
  • First Published: 26 October 2017
Research Article
Open Access

Chemical Composition and Pharmacological Effects of Geopropolis Produced by Melipona quadrifasciata anthidioides

Cintia Miranda dos Santos,  Jaqueline Ferreira Campos,  Helder Freitas dos Santos,  José Benedito Perrella Balestieri,  Denise Brentan Silva,  Kely de Picoli Souza,  Carlos Alexandre Carollo,  Leticia M. Estevinho,  Edson Lucas dos Santos, 
  • First Published: 26 October 2017
Review Article
Open Access

Nrf2, a Potential Therapeutic Target against Oxidative Stress in Corneal Diseases

Xiu-Fen Liu,  Dan-Dan Zhou,  Tian Xie,  Tayyab Hamid Malik,  Cheng-Bo Lu,  Hai-Jun Li,  Fan Wang,  Chang Shu,  Cong Liu,  Cheng-Wei Lu,  Ji-Long Hao, 
  • First Published: 25 October 2017
Research Article
Open Access

Oxidative Stress Alters the Profile of Transcription Factors Related to Early Development on In Vitro Produced Embryos

Roberta Ferreira Leite,  Kelly Annes,  Jessica Ispada,  Camila Bruna de Lima,  Érika Cristina dos Santos,  Patricia Kubo Fontes,  Marcelo Fábio Gouveia Nogueira,  Marcella Pecora Milazzotto, 
  • First Published: 25 October 2017

Research Article
Open Access

Sirt1 Protects Endothelial Cells against LPS-Induced Barrier Dysfunction

Weijin Zhang,  Yaoyuan Zhang,  Xiaohua Guo,  Zhenhua Zeng,  Jie Wu,  Yanan Liu,  Jing He,  Ruiting Wang,  Qiaobing Huang,  Zhongqing Chen, 
  • First Published: 25 October 2017
Review Article
Open Access

Generation and Role of Reactive Oxygen and Nitrogen Species Induced by Plasma, Lasers, Chemical Agents, and Other Systems in Dentistry

Nayansi Jha,  Jae Jun Ryu,  Eun Ha Choi,  Nagendra Kumar Kaushik, 
  • First Published: 24 October 2017
Review Article
Open Access

Dietary Polyphenols in the Prevention of Stroke

A. Tressera-Rimbau,  S. Arranz,  M. Eder,  A. Vallverdú-Queralt, 
  • First Published: 24 October 2017
Review Article
Open Access

Oxidative Stress Modulation and ROS-Mediated Toxicity in Cancer: A Review on In Vitro Models for Plant-Derived Compounds

María José Vallejo,  Lizeth Salazar,  Marcelo Grijalva, 
  • First Published: 24 October 2017
Research Article
Open Access

Ginsenoside Rg1 Ameliorates Behavioral Abnormalities and Modulates the Hippocampal Proteomic Change in Triple Transgenic Mice of Alzheimer’s Disease

Lulin Nie,  Junxia Xia,  Honglian Li,  Zaijun Zhang,  Ying Yang,  Xinfeng Huang,  Zhendan He,  Jianjun Liu,  Xifei Yang, 
  • First Published: 24 October 2017
Review Article
Open Access

Roles and Mechanisms of Herbal Medicine for Diabetic Cardiomyopathy: Current Status and Perspective

Jinfan Tian,  Yingke Zhao,  Yanfei Liu,  Yue Liu,  Keji Chen,  Shuzheng Lyu, 
  • First Published: 24 October 2017
Review Article
Open Access

Cardiac Nonmyocyte Cell Functions and Crosstalks in Response to Cardiotoxic Drugs

Jessica Gambardella,  Bruno Trimarco,  Guido Iaccarino,  Daniela Sorriento, 
  • First Published: 22 October 2017
Research Article
Open Access

Acute Exposure to Cigarette Smoking Followed by Myocardial Infarction Aggravates Renal Damage in an In Vivo Mouse Model

Firas Kobeissy,  Abdullah Shaito,  Abdullah Kaplan,  Lama Baki,  Hassan Hayek,  Carole Dagher-Hamalian,  Ali Nehme,  Rana Ghali,  Emna Abidi,  Ahmad Husari,  Asad Zeidan,  Fouad A. Zouein,  Kazem Zibara, 
  • First Published: 22 October 2017
Research Article
Open Access

Antihypertensive Effects of Roselle-Olive Combination in L-NAME-Induced Hypertensive Rats

Rehab F. Abdel-Rahman,  Alyaa F. Hessin,  Marwan Abdelbaset,  Hanan A. Ogaly,  Reham M. Abd-Elsalam,  Salah M. Hassan, 
  • First Published: 22 October 2017
Research Article
Open Access

Resveratrol and Montelukast Alleviate Paraquat-Induced Hepatic Injury in Mice: Modulation of Oxidative Stress, Inflammation, and Apoptosis

Noha A. El-Boghdady,  Nourtan F. Abdeltawab,  Mohammed M. Nooh, 
  • First Published: 22 October 2017
Research Article
Open Access

Resveratrol Ameliorates Mitochondrial Elongation via Drp1/Parkin/PINK1 Signaling in Senescent-Like Cardiomyocytes

Xuecong Ren,  Li Chen,  Jing Xie,  Zhifeng Zhang,  Gengting Dong,  Jie Liang,  Liang Liu,  Hua Zhou,  Pei Luo, 
  • First Published: 22 October 2017
Review Article
Open Access

Involvement of Mitochondrial Disorders in Septic Cardiomyopathy

Arthur Durand,  Thibault Duburcq,  Thibault Dekeyser,  Remi Neviere,  Michael Howsam,  Raphael Favory,  Sebastien Preau, 
  • First Published: 22 October 2017
Research Article
Open Access

Proinflammatory Cytokines Are Soluble Mediators Linked with Ventricular Arrhythmias and Contractile Dysfunction in a Rat Model of Metabolic Syndrome

Evaristo Fernández-Sada,  Alejandro Torres-Quintanilla,  Christian Silva-Platas,  Noemí García,  B. Cicero Willis,  César Rodríguez-Rodríguez,  Erasmo De la Peña,  Judith Bernal-Ramírez,  Niria Treviño-Saldaña,  Yuriana Oropeza-Almazán,  Elena C. Castillo,  Leticia Elizondo-Montemayor,  Karla Carvajal,  Gerardo García-Rivas, 
  • First Published: 19 October 2017
Research Article
Open Access

Increased Oxidative Damage of RNA in Early-Stage Nephropathy in db/db Mice

Wan-Xia Wang,  Shun-Bin Luo,  Ping Jiang,  Meng-Ming Xia,  Ai-lian Hei,  Yong-Hui Mao,  Chuan-Bao Li,  Guo-Xin Hu,  Jian-Ping Cai, 
  • First Published: 19 October 2017
Research Article
Open Access

Acute Strenuous Exercise Induces an Imbalance on Histone H4 Acetylation/Histone Deacetylase 2 and Increases the Proinflammatory Profile of PBMC of Obese Individuals

Gilson P. Dorneles,  Maria Carolina R. Boeira,  Lucas L. Schipper,  Ivy R. V. Silva,  Viviane R. Elsner,  Pedro Dal Lago,  Alessandra Peres,  Pedro R. T. Romão, 
  • First Published: 19 October 2017
Research Article
Open Access

Slower Dynamics and Aged Mitochondria in Sporadic Alzheimer’s Disease

Patricia Martín-Maestro,  Ricardo Gargini,  Esther García,  George Perry,  Jesús Avila,  Vega García-Escudero, 
  • First Published: 19 October 2017

Research Article
Open Access

Carlina vulgaris L. as a Source of Phytochemicals with Antioxidant Activity

Maciej Strzemski,  Magdalena Wójciak-Kosior,  Ireneusz Sowa,  Daniel Załuski,  Wojciech Szwerc,  Jan Sawicki,  Ryszard Kocjan,  Marcin Feldo,  Sławomir Dresler, 
  • First Published: 18 October 2017
Research Article
Open Access

Oxidative Modification of Blood Serum Proteins in Multiple Sclerosis after Interferon Beta and Melatonin Treatment

Monika Adamczyk-Sowa,  Sabina Galiniak,  Ewa Żyracka,  Michalina Grzesik,  Katarzyna Naparło,  Paweł Sowa,  Grzegorz Bartosz,  Izabela Sadowska-Bartosz, 
  • First Published: 18 October 2017
Review Article
Open Access

Oxidative Stress and Cellular Response to Doxorubicin: A Common Factor in the Complex Milieu of Anthracycline Cardiotoxicity

Donato Cappetta,  Antonella De Angelis,  Luigi Sapio,  Lucia Prezioso,  Michela Illiano,  Federico Quaini,  Francesco Rossi,  Liberato Berrino,  Silvio Naviglio,  Konrad Urbanek, 
  • First Published: 18 October 2017
Research Article
Open Access

Ginger Oleoresin Alleviated γ-Ray Irradiation-Induced Reactive Oxygen Species via the Nrf2 Protective Response in Human Mesenchymal Stem Cells

Kaihua Ji,  Lianying Fang,  Hui Zhao,  Qing Li,  Yang Shi,  Chang Xu,  Yan Wang,  Liqing Du,  Jinhan Wang,  Qiang Liu, 
  • First Published: 18 October 2017
Research Article
Open Access

Rhinacanthin C Alleviates Amyloid-β Fibrils’ Toxicity on Neurons and Attenuates Neuroinflammation Triggered by LPS, Amyloid-β, and Interferon-γ in Glial Cells

Kai-An Chuang,  Ming-Han Li,  Ni-Hsuan Lin,  Chih-Hsuan Chang,  I-Huang Lu,  I-Hong Pan,  Tomoya Takahashi,  Ming-Der Perng,  Shu-Fang Wen, 
  • First Published: 18 October 2017
Review Article
Open Access

Molecular Mechanisms Responsible for Increased Vulnerability of the Ageing Oocyte to Oxidative Damage

Bettina P. Mihalas,  Kate A. Redgrove,  Eileen A. McLaughlin,  Brett Nixon, 
  • First Published: 18 October 2017
Research Article
Open Access

Exercise Inhibits the Effects of Smoke-Induced COPD Involving Modulation of STAT3

Maysa Alves Rodrigues Brandao-Rangel,  Andre Luis Lacerda Bachi,  Manoel Carneiro Oliveira-Junior,  Asghar Abbasi,  Adriano Silva-Renno,  Auriléia Aparecida de Brito,  Ana Paula Ligeiro de Oliveira,  Alessandra Choqueta Toledo-Arruda,  Maria Gabriela Belvisi,  Rodolfo Paula Vieira, 
  • First Published: 18 October 2017
Research Article
Open Access

Protective Effects and Possible Mechanisms of Ergothioneine and Hispidin against Methylglyoxal-Induced Injuries in Rat Pheochromocytoma Cells

Tuzz-Ying Song,  Nae-Cherng Yang,  Chien-Lin Chen,  Thuy Lan Vo Thi, 
  • First Published: 17 October 2017

Corrigendum
Open Access

Corrigendum to “Hydrogen Sulfide Prevents Formation of Reactive Oxygen Species through PI3K/Akt Signaling and Limits Ventilator-Induced Lung Injury”

Sashko Georgiev Spassov,  Rosa Donus,  Paul Mikael Ihle,  Helen Engelstaedter,  Alexander Hoetzel,  Simone Faller, 
  • First Published: 16 October 2017

Review Article
Open Access

The Roles of ROS in Cancer Heterogeneity and Therapy

Paulo Luiz de Sá Junior,  Diana Aparecida Dias Câmara,  Allan Saj Porcacchia,  Pâmela Maria Moreira Fonseca,  Salomão Doria Jorge,  Rodrigo Pinheiro Araldi,  Adilson Kleber Ferreira, 
  • First Published: 16 October 2017
Research Article
Open Access

Troxerutin Reduces Kidney Damage against BDE-47-Induced Apoptosis via Inhibiting NOX2 Activity and Increasing Nrf2 Activity

Qun Shan,  Juan Zhuang,  Guihong Zheng,  Zifeng Zhang,  Yanqiu Zhang,  Jun Lu,  Yuanlin Zheng, 
  • First Published: 15 October 2017
Review Article
Open Access

Uncoupling Protein 2: A Key Player and a Potential Therapeutic Target in Vascular Diseases

Giorgia Pierelli,  Rosita Stanzione,  Maurizio Forte,  Serena Migliarino,  Marika Perelli,  Massimo Volpe,  Speranza Rubattu, 
  • First Published: 15 October 2017
Research Article
Open Access

Effect of Chronic Administration of Resveratrol on Cognitive Performance during Aging Process in Rats

A. R. Navarro-Cruz,  R. Ramírez y Ayala,  C. Ochoa-Velasco,  E. Brambila,  R. Avila-Sosa,  S. Pérez-Fernández,  J. C. Morales-Medina,  P. Aguilar-Alonso, 
  • First Published: 15 October 2017
Research Article
Open Access

Cytoprotective Effects of Citicoline and Homotaurine against Glutamate and High Glucose Neurotoxicity in Primary Cultured Retinal Cells

Sergio Davinelli,  Flavia Chiosi,  Roberto Di Marco,  Ciro Costagliola,  Giovanni Scapagnini, 
  • First Published: 15 October 2017
Research Article
Open Access

Effects of Novel Nitric Oxide-Releasing Molecules against Oxidative Stress on Retinal Pigmented Epithelial Cells

Valeria Pittalà,  Annamaria Fidilio,  Francesca Lazzara,  Chiara Bianca Maria Platania,  Loredana Salerno,  Roberta Foresti,  Filippo Drago,  Claudio Bucolo, 
  • First Published: 12 October 2017
Research Article
Open Access

Mitochondria-Targeted Antioxidant SkQ1 Prevents Anesthesia-Induced Dry Eye Syndrome

Evgeni Yu. Zernii,  Olga S. Gancharova,  Viktoriia E. Baksheeva,  Marina O. Golovastova,  Ekaterina I. Kabanova,  Marina S. Savchenko,  Veronika V. Tiulina,  Larisa F. Sotnikova,  Andrey A. Zamyatnin Jr.,  Pavel P. Philippov,  Ivan I. Senin, 
  • First Published: 12 October 2017
Research Article
Open Access

Neuroprotective and Cognitive-Enhancing Effects of Microencapsulation of Mulberry Fruit Extract in Animal Model of Menopausal Women with Metabolic Syndrome

Supannika Kawvised,  Jintanaporn Wattanathorn,  Wipawee Thukham-mee, 
  • First Published: 12 October 2017
Research Article
Open Access

Contribution and Interactions of Hydroxycinnamic Acids Found in Bran and Wholegrain Sorghum (Sorghum bicolor L. Moench): Effects on the Antioxidant Capacity and Inhibition of Human Erythrocyte Hemolysis

Norma Julieta Salazar-López,  Gustavo A. González-Aguilar,  Guadalupe Loarca-Piña,  Francisco J. Cinco-Moroyoqui,  Ofelia Rouzaud-Sández,  J. Abraham Domínguez-Avila,  Maribel Robles-Sánchez, 
  • First Published: 12 October 2017
Research Article
Open Access

Ghrelin Protects Human Lens Epithelial Cells against Oxidative Stress-Induced Damage

Jie Bai,  Fan Yang,  Li Dong,  Yi Zheng, 
  • First Published: 10 October 2017
Research Article
Open Access

Cytotoxicity, Oxidative Stress, Cell Cycle Arrest, and Mitochondrial Apoptosis after Combined Treatment of Hepatocarcinoma Cells with Maleic Anhydride Derivatives and Quercetin

Gabriela Carrasco-Torres,  Rafael Baltiérrez-Hoyos,  Erik Andrade-Jorge,  Saúl Villa-Treviño,  José Guadalupe Trujillo-Ferrara,  Verónica Rocío Vásquez-Garzón, 
  • First Published: 10 October 2017
Research Article
Open Access

Increasing the Fungicidal Action of Amphotericin B by Inhibiting the Nitric Oxide-Dependent Tolerance Pathway

Kim Vriens,  Phalguni Tewari Kumar,  Caroline Struyfs,  Tanne L. Cools,  Pieter Spincemaille,  Tadej Kokalj,  Belém Sampaio-Marques,  Paula Ludovico,  Jeroen Lammertyn,  Bruno P. A. Cammue,  Karin Thevissen, 
  • First Published: 10 October 2017
Research Article
Open Access

Effect of ALDH2 on High Glucose-Induced Cardiac Fibroblast Oxidative Stress, Apoptosis, and Fibrosis

Xiaoyu Gu,  Tingting Fang,  Pinfang Kang,  Junfeng Hu,  Ying Yu,  Zhenghong Li,  Xiangyang Cheng,  Qin Gao, 
  • First Published: 09 October 2017
Review Article
Open Access

Redox Regulation of Inflammatory Processes Is Enzymatically Controlled

Inken Lorenzen,  Lisa Mullen,  Sander Bekeschus,  Eva-Maria Hanschmann, 
  • First Published: 08 October 2017
Editorial
Open Access

New Insights into the Benefits of Physical Activity and Exercise for Aging and Chronic Disease

James E. Turner,  Vitor A. Lira,  Patricia C. Brum, 
  • First Published: 08 October 2017
Editorial
Open Access

Magnesium and Other Biometals in Oxidative Medicine and Redox Biology

Martin Kolisek,  Rhian M. Touyz,  Andrea Romani,  Mario Barbagallo, 
  • First Published: 04 October 2017
Research Article
Open Access

Mechanism of Mechanical Trauma-Induced Extracellular Matrix Remodeling of Fibroblasts in Association with Nrf2/ARE Signaling Suppression Mediating TGF-β1/Smad3 Signaling Inhibition

Jianming Tang,  Bingshu Li,  Cheng Liu,  Yang Li,  Qiannan Li,  Linlin Wang,  Jie Min,  Ming Hu,  Shasha Hong,  Li Hong, 
  • First Published: 03 October 2017
Research Article
Open Access

Cardioprotective Effect of Resveratrol in a Postinfarction Heart Failure Model

Adam Riba,  Laszlo Deres,  Balazs Sumegi,  Kalman Toth,  Eszter Szabados,  Robert Halmosi, 
  • First Published: 03 October 2017
Research Article
Open Access

MicroRNA-93 Regulates Hypoxia-Induced Autophagy by Targeting ULK1

Wen Li,  Yue Yang,  Zhaoyu Ba,  Shupeng Li,  Hao Chen,  Xiaoyan Hou,  Linlin Ma,  Pengcheng He,  Lei Jiang,  Longxuan Li,  Rongrong He,  Liangqing Zhang,  Du Feng, 
  • First Published: 03 October 2017
Research Article
Open Access

Impact of Atherosclerosis- and Diabetes-Related Dicarbonyls on Vascular Endothelial Permeability: A Comparative Assessment

Mikhail V. Samsonov,  Asker Y. Khapchaev,  Alexander V. Vorotnikov,  Tatyana N. Vlasik,  Elena V. Yanushevskaya,  Maria V. Sidorova,  Evgeniy E. Efremov,  Vadim Z. Lankin,  Vladimir P. Shirinsky, 
  • First Published: 02 October 2017
Research Article
Open Access

Blood-Based Bioenergetic Profiling Reflects Differences in Brain Bioenergetics and Metabolism

Daniel J. Tyrrell,  Manish S. Bharadwaj,  Matthew J. Jorgensen,  Thomas C. Register,  Carol Shively,  Rachel N. Andrews,  Bryan Neth,  C. Dirk Keene,  Akiva Mintz,  Suzanne Craft,  Anthony J. A. Molina, 
  • First Published: 02 October 2017
Research Article
Open Access

Curcumin Reverses the Diazepam-Induced Cognitive Impairment by Modulation of Oxidative Stress and ERK 1/2/NF-κB Pathway in Brain

Alexandra C. Sevastre-Berghian,  Vlad Făgărăsan,  Vlad A. Toma,  Ioana Bâldea,  Diana Olteanu,  Remus Moldovan,  Nicoleta Decea,  Gabriela A. Filip,  Simona V. Clichici, 
  • First Published: 02 October 2017
Research Article
Open Access

Mutation Spectrum Induced by 8-Bromoguanine, a Base Damaged by Reactive Brominating Species, in Human Cells

Kazuya Shinmura,  Hisami Kato,  Masanori Goto,  Hong Tao,  Yusuke Inoue,  Satoki Nakamura,  Haruki Yoshida,  Emi Tsuzaki,  Haruhiko Sugimura, 
  • First Published: 30 September 2017
Research Article
Open Access

Generation and Bioenergetic Profiles of Cybrids with East Asian mtDNA Haplogroups

Huaibin Zhou,  Ke Nie,  Ruyi Qiu,  Jingting Xiong,  Xiaoli Shao,  Bingqian Wang,  Lijun Shen,  Jianxin Lyu,  Hezhi Fang, 
  • First Published: 28 September 2017
Review Article
Open Access

Oxidative Stress and Acute Kidney Injury in Critical Illness: Pathophysiologic Mechanisms—Biomarkers—Interventions, and Future Perspectives

Paraskevi Pavlakou,  Vassilios Liakopoulos,  Theodoros Eleftheriadis,  Michael Mitsis,  Evangelia Dounousi, 
  • First Published: 28 September 2017
Research Article
Open Access

Protective Effects of Oral Astaxanthin Nanopowder against Ultraviolet-Induced Photokeratitis in Mice

Fumiya Harada,  Tetsuro Morikawa,  Anton Lennikov,  Anthony Mukwaya,  Mira Schaupper,  Osamu Uehara,  Rie Takai,  Koki Yoshida,  Jun Sato,  Yukihiro Horie,  Hiroyuki Sakaguchi,  Ching-Zong Wu,  Yoshihiro Abiko,  Neil Lagali,  Nobuyoshi Kitaichi, 
  • First Published: 28 September 2017
Research Article
Open Access

Oxidative Stress Regulation on Endothelial Cells by Hydrophilic Astaxanthin Complex: Chemical, Biological, and Molecular Antioxidant Activity Evaluation

M. Zuluaga,  A. Barzegari,  D. Letourneur,  V. Gueguen,  G. Pavon-Djavid, 
  • First Published: 27 September 2017
Research Article
Open Access

Platelet Carbonic Anhydrase II, a Forgotten Enzyme, May Be Responsible for Aspirin Resistance

M. Jakubowski,  J. Dębski,  E. Szahidewicz-Krupska,  A. Turek-Jakubowska,  J. Gawryś,  K. Gawryś,  R. Skomro,  A. Derkacz,  A. Doroszko, 
  • First Published: 27 September 2017
Research Article
Open Access

Haptoglobin Genotype and Outcome after Subarachnoid Haemorrhage: New Insights from a Meta-Analysis

Ben Gaastra,  James Glazier,  Diederik Bulters,  Ian Galea, 
  • First Published: 26 September 2017

Research Article
Open Access

Chemical Profile and Antioxidant Activity of the Oil from Peony Seeds (Paeonia suffruticosa Andr.)

Xin Yang,  Di Zhang,  Li-min Song,  Qian Xu,  Hong Li,  Hui Xu, 
  • First Published: 26 September 2017
Research Article
Open Access

Oxidative Stress Delays Prometaphase/Metaphase of the First Cleavage in Mouse Zygotes via the MAD2L1-Mediated Spindle Assembly Checkpoint

Que Wu,  Zhiling Li,  Yue Huang,  Diting Qian,  Man Chen,  Wanfen Xiao,  Bin Wang, 
  • First Published: 25 September 2017
Review Article
Open Access

Treatment of the Fluoroquinolone-Associated Disability: The Pathobiochemical Implications

Krzysztof Michalak,  Aleksandra Sobolewska-Włodarczyk,  Marcin Włodarczyk,  Justyna Sobolewska,  Piotr Woźniak,  Bogusław Sobolewski, 
  • First Published: 25 September 2017
Editorial
Open Access

Brain Injury due to Mechanical Trauma and Ischemic-Hypoxic Insult: Biomarkers of Brain Injury and Oxidative Stress

Margherita Neri,  Andreas Büttner,  Vittorio Fineschi, 
  • First Published: 24 September 2017
Research Article
Open Access

Acidic Polysaccharide from Angelica sinensis Reverses Anemia of Chronic Disease Involving the Suppression of Inflammatory Hepcidin and NF-κB Activation

Kaiping Wang,  Jun Wu,  Fang Cheng,  Xiao Huang,  Fang Zeng,  Yu Zhang, 
  • First Published: 24 September 2017
Erratum
Open Access

Erratum to “Is p53 Involved in Tissue-Specific Insulin Resistance Formation?”

Justyna Strycharz,  Jozef Drzewoski,  Janusz Szemraj,  Agnieszka Sliwinska, 
  • First Published: 24 September 2017

Research Article
Open Access

Oxygen-Sensing Nox4 Generates Genotoxic ROS to Induce Premature Senescence of Nucleus Pulposus Cells through MAPK and NF-κB Pathways

Chencheng Feng,  Yang Zhang,  Minghui Yang,  Minghong Lan,  Huan Liu,  Bo Huang,  Yue Zhou, 
  • First Published: 24 September 2017
Review Article
Open Access

The Role of Antioxidant Enzymes in the Ovaries

Shan Wang,  Guolin He,  Meng Chen,  Tao Zuo,  Wenming Xu,  Xinghui Liu, 
  • First Published: 24 September 2017
Research Article
Open Access

Potassium Ascorbate with Ribose: Promising Therapeutic Approach for Melanoma Treatment

Carlotta Cavicchio,  Mascia Benedusi,  Erika Pambianchi,  Alessandra Pecorelli,  Franco Cervellati,  Vinno Savelli,  Duccio Calamandrei,  Emilia Maellaro,  Giorgio Rispoli,  Emanuela Maioli,  Giuseppe Valacchi, 
  • First Published: 24 September 2017
Erratum
Open Access

Erratum to “Impact of Yoga and Meditation on Cellular Aging in Apparently Healthy Individuals: A Prospective, Open-Label Single-Arm Exploratory Study”

Madhuri Tolahunase,  Rajesh Sagar,  Rima Dada, 
  • First Published: 24 September 2017

Erratum
Open Access

Erratum to “Nutritional and Lifestyle Interventions for Age-Related Macular Degeneration: A Review”

Ângela Carneiro,  José Paulo Andrade, 
  • First Published: 24 September 2017

Research Article
Open Access

Myricetin Possesses Potential Protective Effects on Diabetic Cardiomyopathy through Inhibiting IκBα/NFκB and Enhancing Nrf2/HO-1

Hai-han Liao,  Jin-xiu Zhu,  Hong Feng,  Jian Ni,  Nan Zhang,  Si Chen,  Huang-jun Liu,  Zheng Yang,  Wei Deng,  Qi-Zhu Tang, 
  • First Published: 24 September 2017

Corrigendum
Open Access

Corrigendum to “Identification of Patients Affected by Mitral Valve Prolapse with Severe Regurgitation: A Multivariable Regression Model”

Paola Songia,  Benedetta Porro,  Mattia Chiesa,  Veronika Myasoedova,  Francesco Alamanni,  Elena Tremoli,  Paolo Poggio, 
  • First Published: 24 September 2017

Erratum
Open Access

Erratum to “Resveratrol Attenuates Copper-Induced Senescence by Improving Cellular Proteostasis”

Liliana Matos,  Alexandra Monteiro Gouveia,  Henrique Almeida, 
  • First Published: 24 September 2017

Research Article
Open Access

Melatonin Supplementation Lowers Oxidative Stress and Regulates Adipokines in Obese Patients on a Calorie-Restricted Diet

Karolina Szewczyk-Golec,  Paweł Rajewski,  Marcin Gackowski,  Celestyna Mila-Kierzenkowska,  Roland Wesołowski,  Paweł Sutkowy,  Marta Pawłowska,  Alina Woźniak, 
  • First Published: 21 September 2017
Review Article
Open Access

Metallothionein in Brain Disorders

Daniel Juárez-Rebollar,  Camilo Rios,  Concepción Nava-Ruíz,  Marisela Méndez-Armenta, 
  • First Published: 20 September 2017
Research Article
Open Access

Edible Bird’s Nest Prevents Menopause-Related Memory and Cognitive Decline in Rats via Increased Hippocampal Sirtuin-1 Expression

Zhiping Hou,  Peiyuan He,  Mustapha Umar Imam,  Jiemen Qi,  Shiying Tang,  Chengjun Song,  Maznah Ismail, 
  • First Published: 20 September 2017
Research Article
Open Access

Biotransformation of Dioscorea nipponica by Rat Intestinal Microflora and Cardioprotective Effects of Diosgenin

Jia-Fu Feng,  Yi-Na Tang,  Hong Ji,  Zhan-Gang Xiao,  Lin Zhu,  Tao Yi, 
  • First Published: 20 September 2017
Review Article
Open Access

The Combination of Physical Exercise with Muscle-Directed Antioxidants to Counteract Sarcopenia: A Biomedical Rationale for Pleiotropic Treatment with Creatine and Coenzyme Q10

Michele Guescini,  Luca Tiano,  Maria Luisa Genova,  Emanuela Polidori,  Sonia Silvestri,  Patrik Orlando,  Carmela Fimognari,  Cinzia Calcabrini,  Vilberto Stocchi,  Piero Sestili, 
  • First Published: 20 September 2017
Erratum
Open Access

Erratum to “Long-Term Treatment of Native LDL Induces Senescence of Cultured Human Endothelial Cells”

Sung-Tack Oh,  Hoon Park,  Hyun Joong Yoon,  Sung Yeul Yang, 
  • First Published: 20 September 2017

Research Article
Open Access

MicroRNA-34a: A Key Regulator in the Hallmarks of Renal Cell Carcinoma

Eman A. Toraih,  Afaf T. Ibrahiem,  Manal S. Fawzy,  Mohammad H. Hussein,  Saeed Awad M. Al-Qahtani,  Aly A. M. Shaalan, 
  • First Published: 20 September 2017
Research Article
Open Access

VLDL Induced Modulation of Nitric Oxide Signalling and Cell Redox Homeostasis in HUVEC

Maria Chiara Magnifico,  Roxana Elena Oberkersch,  Azzurra Mollo,  Luca Giambelli,  Yasmine Grooten,  Paolo Sarti,  Graciela Cristina Calabrese,  Marzia Arese, 
  • First Published: 20 September 2017
Research Article
Open Access

Effects of Chimonanthus nitens Oliv. Leaf Extract on Glycolipid Metabolism and Antioxidant Capacity in Diabetic Model Mice

Hui Chen,  Yan Jiang,  Zhanwei Yang,  Wenbing Hu,  Lei Xiong,  Ning Wang,  Xin Liu,  Guodong Zheng,  Kehui Ouyang,  Wenjun Wang, 
  • First Published: 19 September 2017
Review Article
Open Access

Oxidative Stress and Endometriosis: A Systematic Review of the Literature

Gennaro Scutiero,  Piergiorgio Iannone,  Giulia Bernardi,  Gloria Bonaccorsi,  Savino Spadaro,  Carlo Alberto Volta,  Pantaleo Greco,  Luigi Nappi, 
  • First Published: 19 September 2017
Review Article
Open Access

Sepsis-Induced Cardiomyopathy: Oxidative Implications in the Initiation and Resolution of the Damage

Vasiliki Tsolaki,  Demosthenes Makris,  Konstantinos Mantzarlis,  Epameinontas Zakynthinos, 
  • First Published: 19 September 2017
Research Article
Open Access

Mitochondria-Targeted Antioxidants SkQ1 and MitoTEMPO Failed to Exert a Long-Term Beneficial Effect in Murine Polymicrobial Sepsis

Pia Rademann,  Adelheid Weidinger,  Susanne Drechsler,  Andras Meszaros,  Johannes Zipperle,  Mohammad Jafarmadar,  Sergiu Dumitrescu,  Ara Hacobian,  Luisa Ungelenk,  Franziska Röstel,  Jozsef Kaszaki,  Andrea Szabo,  Vladimir P. Skulachev,  Michael Bauer,  Soheyl Bahrami,  Sebastian Weis,  Andrey V. Kozlov,  Marcin F. Osuchowski, 
  • First Published: 19 September 2017
Research Article
Open Access

Inhibition of Caveolae Contributes to Propofol Preconditioning-Suppressed Microvesicles Release and Cell Injury by Hypoxia-Reoxygenation

Fan Deng,  Shuang Wang,  Shuyun Cai,  Zhe Hu,  Riping Xu,  Jingjing Wang,  Du Feng,  Liangqing Zhang, 
  • First Published: 19 September 2017
Research Article
Open Access

Antioxidant and Antifibrotic Effect of a Herbal Formulation In Vitro and in the Experimental Andropause via Nrf2/HO-1 Signaling Pathway

Woong Jin Bae,  Guan Qun Zhu,  Sae Woong Choi,  Hyun Cheol Jeong,  Fahad Bashraheel,  Kang Sup Kim,  Su Jin Kim,  Hyuk Jin Cho,  U Syn Ha,  Sung Hoo Hong,  Ji Youl Lee,  Hyun-A Oh,  Hye Cheong Koo,  Do Ram Kim,  Sung Yeoun Hwang,  Sae Woong Kim, 
  • First Published: 17 September 2017
Review Article
Open Access

Effects of Photobiomodulation Therapy on Oxidative Stress in Muscle Injury Animal Models: A Systematic Review

Solange Almeida dos Santos,  Andrey Jorge Serra,  Tatiane Garcia Stancker,  Maíra Cecília Brandão Simões,  Marcia Ataíze dos Santos Vieira,  Ernesto Cesar Leal-Junior,  Marko Prokic,  Andrea Vasconsuelo,  Simone Silva Santos,  Paulo de Tarso Camillo de Carvalho, 
  • First Published: 17 September 2017
Research Article
Open Access

Comparative Analysis of AGE and RAGE Levels in Human Somatic and Embryonic Stem Cells under H2O2-Induced Noncytotoxic Oxidative Stress Conditions

Maria Barandalla,  Elisa Haucke,  Bernd Fischer,  Alexander Navarrete Santos,  Silvia Colleoni,  Cesare Galli,  Anne Navarrete Santos,  Giovanna Lazzari, 
  • First Published: 17 September 2017
Research Article
Open Access

Cardiovascular Protective Effects of Salvianic Acid A on db/db Mice with Elevated Homocysteine Level

Lei Gao,  Parco M. Siu,  Shun-wan Chan,  Christopher W. K. Lai, 
  • First Published: 17 September 2017
Research Article
Open Access

NLRP3 Inflammasome Activation-Mediated Pyroptosis Aggravates Myocardial Ischemia/Reperfusion Injury in Diabetic Rats

Zhen Qiu,  Shaoqing Lei,  Bo Zhao,  Yang Wu,  Wating Su,  Min Liu,  Qingtao Meng,  Bin Zhou,  Yan Leng,  Zhong-yuan Xia, 
  • First Published: 14 September 2017
Research Article
Open Access

β-Naphthoflavone-Induced Mitochondrial Respiratory Damage in Cyp1 Knockout Mouse and in Cell Culture Systems: Attenuation by Resveratrol Treatment

Suresh Kumar Anandasadagopan,  Naveen M. Singh,  Haider Raza,  Seema Bansal,  Venkatesh Selvaraj,  Shilpee Singh,  Anindya Roy Chowdhury,  Nicolae Adrian Leu,  Narayan G. Avadhani, 
  • First Published: 14 September 2017
Review Article
Open Access

The Role of Nrf2 in Cardiovascular Function and Disease

Sandro Satta,  Ayman M. Mahmoud,  Fiona L. Wilkinson,  M. Yvonne Alexander,  Stephen J. White, 
  • First Published: 14 September 2017
Research Article
Open Access

Effect of Multicomponent Training on Blood Pressure, Nitric Oxide, Redox Status, and Physical Fitness in Older Adult Women: Influence of Endothelial Nitric Oxide Synthase (NOS3) Haplotypes

Atila Alexandre Trapé,  Elisangela Aparecida da Silva Lizzi,  Thiago Correa Porto Gonçalves,  Jhennyfer Aline Lima Rodrigues,  Simone Sakagute Tavares,  Riccardo Lacchini,  Lucas Cezar Pinheiro,  Graziele Cristina Ferreira,  José Eduardo Tanus-Santos,  Paula Payão Ovídio,  Alceu Afonso Jordão,  André Mourão Jacomini,  Anderson Saranz Zago,  Carlos Roberto Bueno Júnior, 
  • First Published: 14 September 2017
Research Article
Open Access

The Synthetic Lignan Secoisolariciresinol Diglucoside Prevents Asbestos-Induced NLRP3 Inflammasome Activation in Murine Macrophages

Ralph A. Pietrofesa,  Patrick Woodruff,  Wei-Ting Hwang,  Priyal Patel,  Shampa Chatterjee,  Steven M. Albelda,  Melpo Christofidou-Solomidou, 
  • First Published: 13 September 2017
Research Article
Open Access

Polydatin Prevents Methylglyoxal-Induced Apoptosis through Reducing Oxidative Stress and Improving Mitochondrial Function in Human Umbilical Vein Endothelial Cells

Ningbo Pang,  Tangting Chen,  Xin Deng,  Ni Chen,  Rong Li,  Meiping Ren,  Yongjie Li,  Mao Luo,  Haiyan Hao,  Jianbo Wu,  Liqun Wang, 
  • First Published: 13 September 2017
Research Article
Open Access

Simvastatin Ameliorates Diabetic Cardiomyopathy by Attenuating Oxidative Stress and Inflammation in Rats

Nawal M. Al-Rasheed,  Nouf M. Al-Rasheed,  Iman H. Hasan,  Maha A. Al-Amin,  Hanaa N. Al-Ajmi,  Raeesa A. Mohamad,  Ayman M. Mahmoud, 
  • First Published: 12 September 2017
Research Article
Open Access

Benign Effect of Extremely Low-Frequency Electromagnetic Field on Brain Plasticity Assessed by Nitric Oxide Metabolism during Poststroke Rehabilitation

Natalia Cichoń,  Piotr Czarny,  Michał Bijak,  Elżbieta Miller,  Tomasz Śliwiński,  Janusz Szemraj,  Joanna Saluk-Bijak, 
  • First Published: 12 September 2017
Research Article
Open Access

Resveratrol Modulation of Protein Expression in parkin-Mutant Human Skin Fibroblasts: A Proteomic Approach

Daniele Vergara,  Antonio Gaballo,  Anna Signorile,  Anna Ferretta,  Paola Tanzarella,  Consiglia Pacelli,  Marco Di Paola,  Tiziana Cocco,  Michele Maffia, 
  • First Published: 12 September 2017
Research Article
Open Access

miR-128 Is Implicated in Stress Responses by Targeting MAFG in Skeletal Muscle Cells

Rocco Caggiano,  Fabio Cattaneo,  Ornella Moltedo,  Giovanni Esposito,  Cinzia Perrino,  Bruno Trimarco,  Rosario Ammendola,  Raffaella Faraonio, 
  • First Published: 12 September 2017
Review Article
Open Access

Cell Signaling with Extracellular Thioredoxin and Thioredoxin-Like Proteins: Insight into Their Mechanisms of Action

Thierry Léveillard,  Najate Aït-Ali, 
  • First Published: 12 September 2017
Research Article
Open Access

The Evaluation of Oxidative Stress Parameters in Serum Patients with Relapsing-Remitting Multiple Sclerosis Treated with II-Line Immunomodulatory Therapy

Bożena Adamczyk,  Sławomir Wawrzyniak,  Sławomir Kasperczyk,  Monika Adamczyk-Sowa, 
  • First Published: 12 September 2017
Review Article
Open Access

Oxidative Stress in Hemodialysis Patients: A Review of the Literature

Vassilios Liakopoulos,  Stefanos Roumeliotis,  Xenia Gorny,  Evangelia Dounousi,  Peter R. Mertens, 
  • First Published: 12 September 2017
Research Article
Open Access

Blockage of NOX2/MAPK/NF-κB Pathway Protects Photoreceptors against Glucose Deprivation-Induced Cell Death

Bin Fan,  Bei-Fen Wang,  Lin Che,  Ying-Jian Sun,  Shu-Yan Liu,  Guang-Yu Li, 
  • First Published: 11 September 2017
Research Article
Open Access

Chronic Variable Stress Is Responsible for Lipid and DNA Oxidative Disorders and Activation of Oxidative Stress Response Genes in the Brain of Rats

Mariola Herbet,  Agnieszka Korga,  Monika Gawrońska-Grzywacz,  Magdalena Izdebska,  Iwona Piątkowska-Chmiel,  Ewa Poleszak,  Andrzej Wróbel,  Włodzimierz Matysiak,  Barbara Jodłowska-Jędrych,  Jarosław Dudka, 
  • First Published: 11 September 2017
Editorial
Open Access

Antioxidant, Anti-Inflammatory, and Microbial-Modulating Activities of Nutraceuticals and Functional Foods

Ilaria Peluso,  Thea Magrone,  Débora Villaño Valencia,  C.-Y. Oliver Chen,  Maura Palmery, 
  • First Published: 10 September 2017
Research Article
Open Access

Diabetes-Related Induction of the Heme Oxygenase System and Enhanced Colocalization of Heme Oxygenase 1 and 2 with Neuronal Nitric Oxide Synthase in Myenteric Neurons of Different Intestinal Segments

Lalitha Chandrakumar,  Mária Bagyánszki,  Zita Szalai,  Diána Mezei,  Nikolett Bódi, 
  • First Published: 10 September 2017
Research Article
Open Access

Probucol Reduces Testicular Torsion/Detorsion-Induced Ischemia/Reperfusion Injury in Rats

Si-Ming Wei,  Yu-Min Huang,  Jian Zhou, 
  • First Published: 10 September 2017
Research Article
Open Access

Effect of Neonatal Exposure to Poly(Ethylene Glycol)-block-Poly(Lactic Acid) Nanoparticles on Oxidative State in Infantile and Adult Female Rats

Monika Dvořáková,  Eva Rollerová,  Soňa Scsuková,  Alžbeta Bujňáková Mlynarčíková,  Lucia Laubertová,  Ingrid Žitňanová, 
  • First Published: 10 September 2017
Research Article
Open Access

NRF2 Is a Potential Modulator of Hyperresistance to Arsenic Toxicity in Stem-Like Keratinocytes

Xiafang Wu,  Bei Yang,  Yuxin Hu,  Ru Sun,  Huihui Wang,  Jingqi Fu,  Yongyong Hou,  Jingbo Pi,  Yuanyuan Xu, 
  • First Published: 10 September 2017
Research Article
Open Access

Pharmacological Basis for Use of Armillaria mellea Polysaccharides in Alzheimer’s Disease: Antiapoptosis and Antioxidation

Shengshu An,  Wenqian Lu,  Yongfeng Zhang,  Qingxia Yuan,  Di Wang, 
  • First Published: 10 September 2017
Research Article
Open Access

Estrogens Protect Calsequestrin-1 Knockout Mice from Lethal Hyperthermic Episodes by Reducing Oxidative Stress in Muscle

Antonio Michelucci,  Simona Boncompagni,  Marta Canato,  Carlo Reggiani,  Feliciano Protasi, 
  • First Published: 10 September 2017
Research Article
Open Access

Mitochondrial Respiration in Intact Peripheral Blood Mononuclear Cells and Sirtuin 3 Activity in Patients with Movement Disorders

Slawomir Michalak,  Jolanta Florczak-Wyspiańska,  Joanna Rybacka-Mossakowska,  Wojciech Ambrosius,  Krystyna Osztynowicz,  Aleksandra Baszczuk,  Wojciech Kozubski,  Ewa Wysocka, 
  • First Published: 10 September 2017
Research Article
Open Access

Role of Diet and Nutritional Supplements in Parkinson’s Disease Progression

Laurie K. Mischley,  Richard C. Lau,  Rachel D. Bennett, 
  • First Published: 10 September 2017
Research Article
Open Access

Expression and Role of the Calcium-Sensing Receptor in Rat Peripheral Blood Polymorphonuclear Neutrophils

Tai-yu Zhai,  Bao-hong Cui,  Lei Zou,  Jing-ya Zeng,  Song Gao,  Qianyu Zhao,  Yuan Wang,  Wan-lin Xie,  Yi-hua Sun, 
  • First Published: 10 September 2017
Research Article
Open Access

Antioxidant Treatment Reduces Formation of Structural Cores and Improves Muscle Function in RYR1Y522S/WT Mice

Antonio Michelucci,  Alessandro De Marco,  Flavia A. Guarnier,  Feliciano Protasi,  Simona Boncompagni, 
  • First Published: 10 September 2017
Review Article
Open Access

The Contribution of Singlet Oxygen to Insulin Resistance

Arnold N. Onyango, 
  • First Published: 07 September 2017
Research Article
Open Access

Bioavailable Concentrations of Delphinidin and Its Metabolite, Gallic Acid, Induce Antioxidant Protection Associated with Increased Intracellular Glutathione in Cultured Endothelial Cells

Katarzyna Goszcz,  Sherine J. Deakin,  Garry G. Duthie,  Derek Stewart,  Ian L. Megson, 
  • First Published: 07 September 2017
Research Article
Open Access

Dietary Flaxseed Oil Prevents Western-Type Diet-Induced Nonalcoholic Fatty Liver Disease in Apolipoprotein-E Knockout Mice

Hao Han,  Fubin Qiu,  Haifeng Zhao,  Haiying Tang,  Xiuhua Li,  Dongxing Shi, 
  • First Published: 07 September 2017
Editorial
Open Access

ROS and Oxidative Stress in Stem Cells

Artur Cieślar-Pobuda,  Jianbo Yue,  Hsin-Chen Lee,  Magdalena Skonieczna,  Yau-Huei Wei, 
  • First Published: 06 September 2017
Research Article
Open Access

circRNA_0046367 Prevents Hepatoxicity of Lipid Peroxidation: An Inhibitory Role against Hepatic Steatosis

Xing-Ya Guo,  Jian-Neng Chen,  Fang Sun,  Yu-Qin Wang,  Qin Pan,  Jian-Gao Fan, 
  • First Published: 05 September 2017
Research Article
Open Access

The Neuroprotective Effects of SIRT1 on NMDA-Induced Excitotoxicity

Xiaorong Yang,  Peipei Si,  Huaping Qin,  Litian Yin,  Liang-Jun Yan,  Ce Zhang, 
  • First Published: 01 September 2017
Research Article
Open Access

Salvianolic Acid A Inhibits OX-LDL Effects on Exacerbating Choroidal Neovascularization via Downregulating CYLD

Ke Mao,  Wanting Shu,  Libin Liu,  Qing Gu,  Qinghua Qiu,  XingWei Wu, 
  • First Published: 01 September 2017

Research Article
Open Access

UPLC-MS/MS Profile of Alkaloids with Cytotoxic Properties of Selected Medicinal Plants of the Berberidaceae and Papaveraceae Families

Anna Och,  Katarzyna Szewczyk,  Łukasz Pecio,  Anna Stochmal,  Daniel Załuski,  Anna Bogucka-Kocka, 
  • First Published: 30 August 2017
Research Article
Open Access

Oleate Prevents Palmitate-Induced Atrophy via Modulation of Mitochondrial ROS Production in Skeletal Myotubes

Hojun Lee,  Jae-Young Lim,  Seung-Jun Choi, 
  • First Published: 30 August 2017
Research Article
Open Access

Effects of Glutathione S-Transferase Gene Polymorphisms and Antioxidant Capacity per Unit Albumin on the Pathogenesis of Chronic Obstructive Pulmonary Disease

Tinghui Cao,  Naijin Xu,  Zhen Wang,  Hui Liu, 
  • First Published: 30 August 2017
Research Article
Open Access

Glycosides from Stevia rebaudiana Bertoni Possess Insulin-Mimetic and Antioxidant Activities in Rat Cardiac Fibroblasts

Cecilia Prata,  Laura Zambonin,  Benedetta Rizzo,  Tullia Maraldi,  Cristina Angeloni,  Francesco Vieceli Dalla Sega,  Diana Fiorentini,  Silvana Hrelia, 
  • First Published: 30 August 2017
Research Article
Open Access

Food Security and Leukocyte Telomere Length in Adult Americans

Mohsen Mazidi,  Andre Pascal Kengne,  Hassan Vatanparast, 
  • First Published: 29 August 2017
Editorial
Open Access

Applications of Antioxidants in Ameliorating Drugs and Xenobiotics Toxicity: Mechanistic Approach

Mohamed M. Abdel-Daim,  Yasser M. Moustafa,  Masakazu Umezawa,  Kota V. Ramana,  Elena Azzini, 
  • First Published: 29 August 2017
Research Article
Open Access

Cold Atmospheric Plasma Induces Apoptosis and Oxidative Stress Pathway Regulation in T-Lymphoblastoid Leukemia Cells

Eleonora Turrini,  Romolo Laurita,  Augusto Stancampiano,  Elena Catanzaro,  Cinzia Calcabrini,  Francesca Maffei,  Matteo Gherardi,  Vittorio Colombo,  Carmela Fimognari, 
  • First Published: 29 August 2017
Review Article
Open Access

Collaborative Power of Nrf2 and PPARγ Activators against Metabolic and Drug-Induced Oxidative Injury

Choongho Lee, 
  • First Published: 27 August 2017
Research Article
Open Access

Comparison of Anti-Inflammatory Effects of Flavonoid-Rich Common and Tartary Buckwheat Sprout Extracts in Lipopolysaccharide-Stimulated RAW 264.7 and Peritoneal Macrophages

Tae Gyu Nam,  Tae-Gyu Lim,  Bong Han Lee,  Sol Lim,  Hee Kang,  Seok Hyun Eom,  Miyoung Yoo,  Hae Won Jang,  Dae-Ok Kim, 
  • First Published: 27 August 2017
Editorial
Open Access

Biomarkers of Oxidative Stress in Experimental Models and Human Studies with Nutraceuticals: Measurement, Interpretation, and Significance 2017

Ilaria Peluso,  Maura Palmery,  Gregor Drummen, 
  • First Published: 27 August 2017
Review Article
Open Access

High Circulating Levels of ANGPTL2: Beyond a Clinical Marker of Systemic Inflammation

Nathalie Thorin-Trescases,  Eric Thorin, 
  • First Published: 24 August 2017
Research Article
Open Access

Testosterone Upregulates the Expression of Mitochondrial ND1 and ND4 and Alleviates the Oxidative Damage to the Nigrostriatal Dopaminergic System in Orchiectomized Rats

Wensheng Yan,  Yunxiao Kang,  Xiaoming Ji,  Shuangcheng Li,  Yingkun Li,  Guoliang Zhang,  Huixian Cui,  Geming Shi, 
  • First Published: 24 August 2017
Research Article
Open Access

Febuxostat Modulates MAPK/NF-κBp65/TNF-α Signaling in Cardiac Ischemia-Reperfusion Injury

Sana Irfan Khan,  Rajiv Kumar Malhotra,  Neha Rani,  Anil Kumar Sahu,  Ameesha Tomar,  Shanky Garg,  Tapas Chandra Nag,  Ruma Ray,  Shreesh Ojha,  Dharamvir Singh Arya,  Jagriti Bhatia, 
  • First Published: 24 August 2017
Research Article
Open Access

Baicalin Attenuates Subarachnoid Hemorrhagic Brain Injury by Modulating Blood-Brain Barrier Disruption, Inflammation, and Oxidative Damage in Mice

Xianqing Shi,  Yongjian Fu,  SongSong Zhang,  Hao Ding,  Jin Chen, 
  • First Published: 24 August 2017
Review Article
Open Access

The Beneficial Effects of Quercetin, Curcumin, and Resveratrol in Obesity

Yueshui Zhao,  Bo Chen,  Jing Shen,  Lin Wan,  Yinxin Zhu,  Tao Yi,  Zhangang Xiao, 
  • First Published: 24 August 2017
Research Article
Open Access

Enhancement of Antioxidant Mechanisms and Reduction of Oxidative Stress in Chickens after the Administration of Drinking Water Enriched with Polyphenolic Powder from Olive Mill Waste Waters

Aliki Papadopoulou,  Konstantinos Petrotos,  Dimitrios Stagos,  Konstantinos Gerasopoulos,  Antonios Maimaris,  Haralampos Makris,  Ioannis Kafantaris,  Sotiria Makri,  Efthalia Kerasioti,  Maria Halabalaki,  Vincent Brieudes,  Georgia Ntasi,  Stylianos Kokkas,  Pavlos Tzimas,  Panagiotis Goulas,  Alexander M. Zakharenko,  Kirill S. Golokhvast,  Aristidis Tsatsakis,  Demetrios Kouretas, 
  • First Published: 24 August 2017
Research Article
Open Access

Exercise Training Restores Cardiac MicroRNA-1 and MicroRNA-29c to Nonpathological Levels in Obese Rats

André C. Silveira,  Tiago Fernandes,  Úrsula P. R. Soci,  João L. P. Gomes,  Diego L. Barretti,  Glória G. F. Mota,  Carlos Eduardo Negrão,  Edilamar M. Oliveira, 
  • First Published: 23 August 2017

Clinical Study
Open Access

Effect of Weight Loss, Exercise, or Both on Undercarboxylated Osteocalcin and Insulin Secretion in Frail, Obese Older Adults

Georgia Colleluori,  Nicola Napoli,  Uma Phadnis,  Reina Armamento-Villareal,  Dennis T. Villareal, 
  • First Published: 23 August 2017
Review Article
Open Access

Modulatory Mechanism of Polyphenols and Nrf2 Signaling Pathway in LPS Challenged Pregnancy Disorders

Tarique Hussain,  Bie Tan,  Gang Liu,  Ghulam Murtaza,  Najma Rahu,  Muhammad Saleem,  Yulong Yin, 
  • First Published: 23 August 2017
Research Article
Open Access

Low-Dose Ionizing Radiation Affects Mesenchymal Stem Cells via Extracellular Oxidized Cell-Free DNA: A Possible Mediator of Bystander Effect and Adaptive Response

V. A. Sergeeva,  E. S. Ershova,  N. N. Veiko,  E. M. Malinovskaya,  A. A. Kalyanov,  L. V. Kameneva,  S. V. Stukalov,  O. A. Dolgikh,  M. S. Konkova,  A. V. Ermakov,  V. P. Veiko,  V. L. Izhevskaya,  S. I. Kutsev,  S. V. Kostyuk, 
  • First Published: 22 August 2017
Corrigendum
Open Access

Corrigendum to “Metformin Decreases Reactive Oxygen Species, Enhances Osteogenic Properties of Adipose-Derived Multipotent Mesenchymal Stem Cells In Vitro, and Increases Bone Density In Vivo”

Krzysztof Marycz,  Krzysztof A. Tomaszewski,  Katarzyna Kornicka,  Brandon Michael Henry,  Sebastian Wroński,  Jacek Tarasiuk,  Monika Maredziak, 
  • First Published: 20 August 2017

Research Article
Open Access

Total Oxidant and Antioxidant Status in Prepubertal Children with Obesity

Grażyna Rowicka,  Hanna Dyląg,  Jadwiga Ambroszkiewicz,  Agnieszka Riahi,  Halina Weker,  Magdalena Chełchowska, 
  • First Published: 20 August 2017
Review Article
Open Access

Role of Oxidative Stress and Mitochondrial Dysfunction in Sepsis and Potential Therapies

Konstantinos Mantzarlis,  Vasiliki Tsolaki,  Epaminondas Zakynthinos, 
  • First Published: 20 August 2017
Research Article
Open Access

Anticataractogenesis and Antiretinopathy Effects of the Novel Protective Agent Containing the Combined Extract of Mango and Vietnamese Coriander in STZ-Diabetic Rats

Jintanaporn Wattanathorn,  Paphaphat Thiraphatthanavong,  Wipawee Thukham-mee,  Supaporn Muchimapura,  Panakaporn Wannanond,  Terdthai Tong-un, 
  • First Published: 20 August 2017
Corrigendum
Open Access

Corrigendum to “Immune Profile of Obese People and In Vitro Effects of Red Grape Polyphenols on Peripheral Blood Mononuclear Cells”

Thea Magrone,  Emilio Jirillo,  Anna Spagnoletta,  Manrico Magrone,  Matteo Antonio Russo,  Sergio Fontana,  Flavia Laforgia,  Ilaria Donvito,  Angelo Campanella,  Franco Silvestris,  Giovanni De Pergola, 
  • First Published: 20 August 2017

Review Article
Open Access

Beer Polyphenols and Menopause: Effects and Mechanisms—A Review of Current Knowledge

Berner Andrée Sandoval-Ramírez,  Rosa M. Lamuela-Raventós,  Ramon Estruch,  Gemma Sasot,  Monica Doménech,  Anna Tresserra-Rimbau, 
  • First Published: 17 August 2017
Review Article
Open Access

Mitochondrial Function and Mitophagy in the Elderly: Effects of Exercise

Osvaldo C. Moreira,  Brisamar Estébanez,  Susana Martínez-Florez,  José A. de Paz,  María J. Cuevas,  Javier González-Gallego, 
  • First Published: 16 August 2017
Research Article
Open Access

Serum Bilirubin Levels and Promoter Variations in HMOX1 and UGT1A1 Genes in Patients with Fabry Disease

Alena Jirásková,  Giulia Bortolussi,  Gabriela Dostálová,  Lenka Eremiášová,  Lubor Golaň,  Vilém Danzig,  Aleš Linhart,  Libor Vítek, 
  • First Published: 16 August 2017
Research Article
Open Access

Seabuckthorn Paste Protects Lipopolysaccharide-Induced Acute Lung Injury in Mice through Attenuation of Oxidative Stress

Leilei Du,  Xiaoxin Hu,  Chu Chen,  Tingting Kuang,  Hengfu Yin,  Li Wan, 
  • First Published: 16 August 2017
Research Article
Open Access

Baicalin Ameliorates Liver Injury Induced by Chronic plus Binge Ethanol Feeding by Modulating Oxidative Stress and Inflammation via CYP2E1 and NRF2 in Mice

Ping He,  Yafeng Wu,  Jianchao Shun,  Yaodong Liang,  Mingliang Cheng,  Yuping Wang, 
  • First Published: 16 August 2017
Research Article
Open Access

Resveratrol-Enriched Rice Attenuates UVB-ROS-Induced Skin Aging via Downregulation of Inflammatory Cascades

Lalita Subedi,  Taek Hwan Lee,  Hussain Mustatab Wahedi,  So-Hyeon Baek,  Sun Yeou Kim, 
  • First Published: 16 August 2017

Review Article
Open Access

Effects of Polyphenol Intake on Metabolic Syndrome: Current Evidences from Human Trials

Gemma Chiva-Blanch,  Lina Badimon, 
  • First Published: 15 August 2017
Review Article
Open Access

Protein Posttranslational Modifications: Roles in Aging and Age-Related Disease

Ana L. Santos,  Ariel B. Lindner, 
  • First Published: 15 August 2017
Research Article
Open Access

The Evaluation of Antioxidant and Anti-Inflammatory Effects of Eucommia ulmoides Flavones Using Diquat-Challenged Piglet Models

Daixiu Yuan,  Tarique Hussain,  Bie Tan,  Yanhong Liu,  Peng Ji,  Yulong Yin, 
  • First Published: 15 August 2017
Research Article
Open Access

Increased Levels of Oxidative Stress Markers, Soluble CD40 Ligand, and Carotid Intima-Media Thickness Reflect Acceleration of Atherosclerosis in Male Patients with Ankylosing Spondylitis in Active Phase and without the Classical Cardiovascular Risk Factors

Agata Stanek,  Armand Cholewka,  Tomasz Wielkoszyński,  Ewa Romuk,  Karolina Sieroń,  Aleksander Sieroń, 
  • First Published: 15 August 2017
Research Article
Open Access

A Cystine-Rich Whey Supplement (Immunocal®) Provides Neuroprotection from Diverse Oxidative Stress-Inducing Agents In Vitro by Preserving Cellular Glutathione

Aimee N. Winter,  Erika K. Ross,  Vamsi Daliparthi,  Whitney A. Sumner,  Danielle M. Kirchhof,  Evan Manning,  Heather M. Wilkins,  Daniel A. Linseman, 
  • First Published: 15 August 2017
Research Article
Open Access

An Extract from the Plant Deschampsia antarctica Protects Fibroblasts from Senescence Induced by Hydrogen Peroxide

Ana Ortiz-Espín,  Esther Morel,  Ángeles Juarranz,  Antonio Guerrero,  Salvador González,  Ana Jiménez,  Francisca Sevilla, 
  • First Published: 15 August 2017
Review Article
Open Access

FOXO Transcriptional Factors and Long-Term Living

Ghulam Murtaza,  Abida Kalsoom Khan,  Rehana Rashid,  Saiqa Muneer,  Syed Muhammad Farid Hasan,  Jianxin Chen, 
  • First Published: 15 August 2017
Corrigendum
Open Access

Corrigendum to “Propofol Attenuates Small Intestinal Ischemia Reperfusion Injury through Inhibiting NADPH Oxidase Mediated Mast Cell Activation”

Xiaoliang Gan,  Dandan Xing,  Guangjie Su,  Shun Li,  Chenfang Luo,  Michael G. Irwin,  Zhengyuan Xia,  Haobo Li,  Ziqing Hei, 
  • First Published: 14 August 2017

Research Article
Open Access

Treatment Effects of Ischemic Stroke by Berberine, Baicalin, and Jasminoidin from Huang-Lian-Jie-Du-Decoction (HLJDD) Explored by an Integrated Metabolomics Approach

Qian Zhang,  Xiaowei Fu,  Junsong Wang,  Minghua Yang,  Lingyi Kong, 
  • First Published: 14 August 2017
Research Article
Open Access

Loss of Sigma-1 Receptor Chaperone Promotes Astrocytosis and Enhances the Nrf2 Antioxidant Defense

Tzu-Yu Weng,  Denise T. Hung,  Tsung-Ping Su,  Shang-Yi A. Tsai, 
  • First Published: 14 August 2017
Corrigendum
Open Access

Corrigendum to “Paricalcitol Pretreatment Attenuates Renal Ischemia-Reperfusion Injury via Prostaglandin E2 Receptor EP4 Pathway”

Yu Ah Hong,  Keum Jin Yang,  So Young Jung,  Ki Cheol Park,  Hyunsu Choi,  Jeong Min Oh,  Sang Ju Lee,  Yoon Kyung Chang,  Cheol WheePark,  Chul Woo Yang,  Suk Young Kim,  Hyeon Seok Hwang, 
  • First Published: 13 August 2017

Research Article
Open Access

Caffeic Acid Phenethyl Ester Reduces Ischemia-Induced Kidney Mitochondrial Injury in Rats

Sonata Trumbeckaite,  Neringa Pauziene,  Darius Trumbeckas,  Mindaugas Jievaltas,  Rasa Baniene, 
  • First Published: 13 August 2017
Research Article
Open Access

Antioxidant and Anti-Inflammatory Effects of Shungite against Ultraviolet B Irradiation-Induced Skin Damage in Hairless Mice

Ma. Easter Joy Sajo,  Cheol-Su Kim,  Soo-Ki Kim,  Kwang Yong Shim,  Tae-Young Kang,  Kyu-Jae Lee, 
  • First Published: 13 August 2017
Research Article
Open Access

Centella asiatica Attenuates Mitochondrial Dysfunction and Oxidative Stress in Aβ-Exposed Hippocampal Neurons

Nora E. Gray,  Jonathan A. Zweig,  Donald G. Matthews,  Maya Caruso,  Joseph F. Quinn,  Amala Soumyanath, 
  • First Published: 13 August 2017
Research Article
Open Access

Rosmarinic Acid Alleviates the Endothelial Dysfunction Induced by Hydrogen Peroxide in Rat Aortic Rings via Activation of AMPK

Hui Zhou,  Baocai Fu,  Bo Xu,  Xiangquan Mi,  Gang Li,  Chengjun Ma,  Jianxin Xie,  Ji Li,  Zhenhua Wang, 
  • First Published: 13 August 2017
Research Article
Open Access

SIRT1 Activation by Resveratrol Alleviates Cardiac Dysfunction via Mitochondrial Regulation in Diabetic Cardiomyopathy Mice

Sai Ma,  Jing Feng,  Ran Zhang,  Jiangwei Chen,  Dong Han,  Xiang Li,  Bo Yang,  Xiujuan Li,  Miaomiao Fan,  Congye Li,  Zuhong Tian,  Yabin Wang,  Feng Cao, 
  • First Published: 13 August 2017
Research Article
Open Access

Increased Mitochondrial Mass and Cytosolic Redox Imbalance in Hippocampal Astrocytes of a Mouse Model of Rett Syndrome: Subcellular Changes Revealed by Ratiometric Imaging of JC-1 and roGFP1 Fluorescence

Dörthe F. Bebensee,  Karolina Can,  Michael Müller, 
  • First Published: 13 August 2017
Review Article
Open Access

Cellular and Molecular Mechanisms of Diabetic Atherosclerosis: Herbal Medicines as a Potential Therapeutic Approach

Jinfan Tian,  Yanfei Liu,  Yue Liu,  Keji Chen,  Shuzheng Lyu, 
  • First Published: 13 August 2017
Review Article
Open Access

Dietary Polyphenols, Mediterranean Diet, Prediabetes, and Type 2 Diabetes: A Narrative Review of the Evidence

Marta Guasch-Ferré,  Jordi Merino,  Qi Sun,  Montse Fitó,  Jordi Salas-Salvadó, 
  • First Published: 13 August 2017
Review Article
Open Access

Aging: Molecular Pathways and Implications on the Cardiovascular System

Arthur José Pontes Oliveira de Almeida,  Thaís Porto Ribeiro,  Isac Almeida de Medeiros, 
  • First Published: 09 August 2017
Research Article
Open Access

Cytokines Genotype-Phenotype Correlation in Nonalcoholic Steatohepatitis

Ioana Corina Bocsan,  Mircea Vasile Milaciu,  Raluca Maria Pop,  Stefan Cristian Vesa,  Lorena Ciumarnean,  Daniela Maria Matei,  Anca Dana Buzoianu, 
  • First Published: 09 August 2017
Research Article
Open Access

Pleiotropic Effects of Biguanides on Mitochondrial Reactive Oxygen Species Production

Alena Pecinova,  Zdenek Drahota,  Jana Kovalcikova,  Nikola Kovarova,  Petr Pecina,  Lukas Alan,  Michal Zima,  Josef Houstek,  Tomas Mracek, 
  • First Published: 09 August 2017
Research Article
Open Access

A New Natural Antioxidant Mixture Protects against Oxidative and DNA Damage in Endothelial Cell Exposed to Low-Dose Irradiation

T. Cervelli,  D. Panetta,  T. Navarra,  S. Gadhiri,  P. Salvadori,  A. Galli,  D. Caramella,  G. Basta,  E. Picano,  S. Del Turco, 
  • First Published: 09 August 2017
Clinical Study
Open Access

Antioxidant Effects of a Hydroxytyrosol-Based Pharmaceutical Formulation on Body Composition, Metabolic State, and Gene Expression: A Randomized Double-Blinded, Placebo-Controlled Crossover Trial

Carmela Colica,  Laura Di Renzo,  Domenico Trombetta,  Antonella Smeriglio,  Sergio Bernardini,  Giorgia Cioccoloni,  Renata Costa de Miranda,  Paola Gualtieri,  Paola Sinibaldi Salimei,  Antonino De Lorenzo, 
  • First Published: 09 August 2017
Research Article
Open Access

Depletion of the Third Complement Component Ameliorates Age-Dependent Oxidative Stress and Positively Modulates Autophagic Activity in Aged Retinas in a Mouse Model

Dorota Rogińska,  Miłosz P. Kawa,  Ewa Pius-Sadowska,  Renata Lejkowska,  Karolina Łuczkowska,  Barbara Wiszniewska,  Kai Kaarniranta,  Jussi J. Paterno,  Christian A. Schmidt,  Bogusław Machaliński,  Anna Machalińska, 
  • First Published: 08 August 2017
Research Article
Open Access

Fucoxanthin, a Marine Carotenoid, Attenuates β-Amyloid Oligomer-Induced Neurotoxicity Possibly via Regulating the PI3K/Akt and the ERK Pathways in SH-SY5Y Cells

Jiajia Lin,  Jie Yu,  Jiaying Zhao,  Ke Zhang,  Jiachen Zheng,  Jialing Wang,  Chunhui Huang,  Jingrong Zhang,  Xiaojun Yan,  William H. Gerwick,  Qinwen Wang,  Wei Cui,  Shan He, 
  • First Published: 08 August 2017
Research Article
Open Access

Markers of Oxidative Stress and Inflammation in Ascites and Plasma in Patients with Platinum-Sensitive, Platinum-Resistant, and Platinum-Refractory Epithelial Ovarian Cancer

Juan Carlos Cantón-Romero,  Alejandra Guillermina Miranda-Díaz,  Jose Luis Bañuelos-Ramírez,  Sandra Carrillo-Ibarra,  Sonia Sifuentes-Franco,  José Alberto Castellanos-González,  Adolfo Daniel Rodríguez-Carrizalez, 
  • First Published: 07 August 2017
Research Article
Open Access

Increased Circulating Levels of Interleukin-6 Induce Perturbation in Redox-Regulated Signaling Cascades in Muscle of Dystrophic Mice

Laura Pelosi,  Laura Forcina,  Carmine Nicoletti,  Bianca Maria Scicchitano,  Antonio Musarò, 
  • First Published: 06 August 2017
Research Article
Open Access

Elucidation of Molecular Mechanisms of Streptozotocin-Induced Oxidative Stress, Apoptosis, and Mitochondrial Dysfunction in Rin-5F Pancreatic β-Cells

Arwa M. T. Al Nahdi,  Annie John,  Haider Raza, 
  • First Published: 06 August 2017
Research Article
Open Access

Stress-Activated Degradation of Sphingolipids Regulates Mitochondrial Function and Cell Death in Yeast

Sara Manzanares-Estreder,  Amparo Pascual-Ahuir,  Markus Proft, 
  • First Published: 06 August 2017
Review Article
Open Access

Oxidative Stress in Pancreatic Beta Cell Regeneration

Jingjing Wang,  Hongjun Wang, 
  • First Published: 03 August 2017
Research Article
Open Access

PPAR-γ Activation Prevents Septic Cardiac Dysfunction via Inhibition of Apoptosis and Necroptosis

Shiyan Peng,  Junmei Xu,  Wei Ruan,  Suobei Li,  Feng Xiao, 
  • First Published: 03 August 2017
Research Article
Open Access

Effect of Emodin on Preventing Postoperative Intra-Abdominal Adhesion Formation

Guangbing Wei,  Yunhua Wu,  Qi Gao,  Cancan Zhou,  Kai Wang,  Cong Shen,  Guanghui Wang,  Kang Wang,  Xuejun Sun,  Xuqi Li, 
  • First Published: 02 August 2017
Editorial
Open Access

Biomarkers of Aging: From Cellular Senescence to Age-Associated Diseases

Maria João Martins,  Miguel Constância,  Delminda Neves,  Andreas Simm, 
  • First Published: 02 August 2017
Research Article
Open Access

Ameliorative Effect of Daidzein on Cisplatin-Induced Nephrotoxicity in Mice via Modulation of Inflammation, Oxidative Stress, and Cell Death

Hongzhou Meng,  Guanghou Fu,  Jie Shen,  Kezhen Shen,  Zhijie Xu,  Yiming Wang,  Baiye Jin,  Hao Pan, 
  • First Published: 02 August 2017
Research Article
Open Access

Genetic Transformation and Hairy Root Induction Enhance the Antioxidant Potential of Lactuca serriola L.

Mohamed A. El-Esawi,  Amr Elkelish,  Hosam O. Elansary,  Hayssam M. Ali,  Mohamed Elshikh,  Jacques Witczak,  Margaret Ahmad, 
  • First Published: 01 August 2017
Research Article
Open Access

Histopathological Changes in the Kidney following Congestive Heart Failure by Volume Overload in Rats

Noureddin B. Aboryag,  Doaa M. Mohamed,  Lukas Dehe,  Mohammed Shaqura,  Sacha Treskatsch,  Mehdi Shakibaei,  Michael Schäfer,  Shaaban A. Mousa, 
  • First Published: 31 July 2017
Research Article
Open Access

3-Hydroxykynurenine and 3-Hydroxyanthranilic Acid Enhance the Toxicity Induced by Copper in Rat Astrocyte Culture

Daniela Ramírez-Ortega,  Alelí Ramiro-Salazar,  Dinora González-Esquivel,  Camilo Ríos,  Benjamín Pineda,  Verónica Pérez de la Cruz, 
  • First Published: 31 July 2017
Research Article
Open Access

Apigenin Alleviates Endotoxin-Induced Myocardial Toxicity by Modulating Inflammation, Oxidative Stress, and Autophagy

Fang Li,  Fangfang Lang,  Huilin Zhang,  Liangdong Xu,  Yidan Wang,  Chunxiao Zhai,  Enkui Hao, 
  • First Published: 30 July 2017
Research Article
Open Access

Cardioprotective Effects of Transfusion of Late-Phase Preconditioned Plasma May Be Induced by Activating the Reperfusion Injury Salvage Kinase Pathway but Not the Survivor Activating Factor Enhancement Pathway in Rats

Yang Zhao,  Zhi-nan Zheng,  Yan-na Pi,  Xue Liang,  San-qing Jin, 
  • First Published: 30 July 2017
Research Article
Open Access

Mulberry Fruit Extract Affords Protection against Ethyl Carbamate-Induced Cytotoxicity and Oxidative Stress

Wei Chen,  Yuting Li,  Tao Bao,  Vemana Gowd, 
  • First Published: 27 July 2017
Research Article
Open Access

Circulating miRNAs in Pediatric Pulmonary Hypertension Show Promise as Biomarkers of Vascular Function

Vitaly O. Kheyfets,  Carmen C. Sucharov,  Uyen Truong,  Jamie Dunning,  Kendall Hunter,  Dunbar Ivy,  Shelley Miyamoto,  Robin Shandas, 
  • First Published: 27 July 2017
Research Article
Open Access

Hypoxia Downregulates MAPK/ERK but Not STAT3 Signaling in ROS-Dependent and HIF-1-Independent Manners in Mouse Embryonic Stem Cells

Jan Kučera,  Julie Netušilová,  Stanislava Sladeček,  Martina Lánová,  Ondřej Vašíček,  Kateřina Štefková,  Jarmila Navrátilová,  Lukáš Kubala,  Jiří Pacherník, 
  • First Published: 27 July 2017
Research Article
Open Access

Diosmin Attenuates Methotrexate-Induced Hepatic, Renal, and Cardiac Injury: A Biochemical and Histopathological Study in Mice

Mohamed M. Abdel-Daim,  Hesham A. Khalifa,  Abdelrahman Ibrahim Abushouk,  Mohamed A. Dkhil,  Saleh A. Al-Quraishy, 
  • First Published: 27 July 2017
Review Article
Open Access

Oxidative Stress: Harms and Benefits for Human Health

Gabriele Pizzino,  Natasha Irrera,  Mariapaola Cucinotta,  Giovanni Pallio,  Federica Mannino,  Vincenzo Arcoraci,  Francesco Squadrito,  Domenica Altavilla,  Alessandra Bitto, 
  • First Published: 27 July 2017
Corrigendum
Open Access

Corrigendum to “Macroautophagy and Selective Mitophagy Ameliorate Chondrogenic Differentiation Potential in Adipose Stem Cells of Equine Metabolic Syndrome: New Findings in the Field of Progenitor Cells Differentiation”

Krzysztof Marycz,  Katarzyna Kornicka,  Jakub Grzesiak,  Agnieszka Śmieszek,  Jolanta Szłapka, 
  • First Published: 27 July 2017

Research Article
Open Access

Green Tea Polyphenols Ameliorate the Early Renal Damage Induced by a High-Fat Diet via Ketogenesis/SIRT3 Pathway

Weijie Yi,  Xiao Xie,  Miying Du,  Yongjun Bu,  Nannan Wu,  Hui Yang,  Chong Tian,  Fangyi Xu,  Siyun Xiang,  Piwei Zhang,  Zhuo Chen,  Xuezhi Zuo,  Chenjiang Ying, 
  • First Published: 26 July 2017
Review Article
Open Access

Honey, Propolis, and Royal Jelly: A Comprehensive Review of Their Biological Actions and Health Benefits

Visweswara Rao Pasupuleti,  Lakhsmi Sammugam,  Nagesvari Ramesh,  Siew Hua Gan, 
  • First Published: 26 July 2017
Research Article
Open Access

Activation of Endocannabinoid Receptor 2 as a Mechanism of Propofol Pretreatment-Induced Cardioprotection against Ischemia-Reperfusion Injury in Rats

Hai-Jing Sun,  Yan Lu,  Hao-Wei Wang,  Hao Zhang,  Shuang-Ran Wang,  Wen-Yun Xu,  Hai-Long Fu,  Xue-Ya Yao,  Feng Yang,  Hong-Bin Yuan, 
  • First Published: 26 July 2017
Review Article
Open Access

Protective Mechanisms of the Mitochondrial-Derived Peptide Humanin in Oxidative and Endoplasmic Reticulum Stress in RPE Cells

Leonid Minasyan,  Parameswaran G. Sreekumar,  David R. Hinton,  Ram Kannan, 
  • First Published: 26 July 2017
Research Article
Open Access

2-Deoxy-D-glucose Restore Glucocorticoid Sensitivity in Acute Lymphoblastic Leukemia via Modification of N-Linked Glycosylation in an Oxygen Tension-Independent Manner

Zaira Leni,  Paulina Ćwiek,  Valeriya Dimitrova,  Andrea S. Dulcey,  Nicola Zamboni,  Cedric Simillion,  Geetha Rossi,  Kurt Leibundgut,  Alexandre Arcaro, 
  • First Published: 26 July 2017
Review Article
Open Access

Long Noncoding RNAs and RNA-Binding Proteins in Oxidative Stress, Cellular Senescence, and Age-Related Diseases

Chongtae Kim,  Donghee Kang,  Eun Kyung Lee,  Jae-Seon Lee, 
  • First Published: 25 July 2017
Research Article
Open Access

Role of Mitochondrial Genome Mutations in Pathogenesis of Carotid Atherosclerosis

Margarita A. Sazonova,  Vasily V. Sinyov,  Anastasia I. Ryzhkova,  Elena V. Galitsyna,  Zukhra B. Khasanova,  Anton Yu Postnov,  Elena I. Yarygina,  Alexander N. Orekhov,  Igor A. Sobenin, 
  • First Published: 25 July 2017

Research Article
Open Access

Oxidative Biochemistry Disbalance and Changes on Proteomic Profile in Salivary Glands of Rats Induced by Chronic Exposure to Methylmercury

Leonardo Oliveira Bittencourt,  Bruna Puty,  Senda Charone,  Walessa Alana Bragança Aragão,  Paulo Mecenas Farias-Junior,  Marcia Cristina Freitas Silva,  Maria Elena Crespo-Lopez,  Aline de Lima Leite,  Marilia Afonso Rabelo Buzalaf,  Rafael Rodrigues Lima, 
  • First Published: 24 July 2017
Review Article
Open Access

Pro- and Antioxidant Functions of the Peroxisome-Mitochondria Connection and Its Impact on Aging and Disease

Amparo Pascual-Ahuir,  Sara Manzanares-Estreder,  Markus Proft, 
  • First Published: 24 July 2017
Research Article
Open Access

Identification of Four Oxidative Stress-Responsive MicroRNAs, miR-34a-5p, miR-1915-3p, miR-638, and miR-150-3p, in Hepatocellular Carcinoma

Yong Wan,  Ruixia Cui,  Jingxian Gu,  Xing Zhang,  Xiaohong Xiang,  Chang Liu,  Kai Qu,  Ting Lin, 
  • First Published: 24 July 2017
Research Article
Open Access

Preliminary Data on the Interaction between Some Biometals and Oxidative Stress Status in Mild Cognitive Impairment and Alzheimer’s Disease Patients

Ioana-Miruna Balmuș,  Stefan-Adrian Strungaru,  Alin Ciobica,  Mircea-Nicusor Nicoara,  Romeo Dobrin,  Gabriel Plavan,  Cristinel Ștefănescu, 
  • First Published: 24 July 2017
Research Article
Open Access

Selaginella bryopteris Aqueous Extract Improves Stability and Function of Cryopreserved Human Mesenchymal Stem Cells

Abhishek Kumar Singh,  Anubhuti Jha,  Arindam Bit,  Andrey P. Kiassov,  Albert A. Rizvanov,  Archit Ojha,  Pooja Bhoi,  Pradeep Kumar Patra,  Awanish Kumar,  Akalabya Bissoyi, 
  • First Published: 24 July 2017
Research Article
Open Access

Modulation of Glutathione Hemostasis by Inhibition of 12/15-Lipoxygenase Prevents ROS-Mediated Cell Death after Hepatic Ischemia and Reperfusion

Moritz Drefs,  Michael N. Thomas,  Markus Guba,  Martin K. Angele,  Jens Werner,  Marcus Conrad,  Christian J. Steib,  Lesca M. Holdt,  Joachim Andrassy,  Andrej Khandoga,  Markus Rentsch, 
  • First Published: 24 July 2017
Review Article
Open Access

Epigenetics and Oxidative Stress in Aging

Amy Guillaumet-Adkins,  Yania Yañez,  Manuel D. Peris-Diaz,  Ines Calabria,  Cora Palanca-Ballester,  Juan Sandoval, 
  • First Published: 20 July 2017
Review Article
Open Access

Functional, Cellular, and Molecular Remodeling of the Heart under Influence of Oxidative Cigarette Tobacco Smoke

Abdullah Kaplan,  Emna Abidi,  Rana Ghali,  George W. Booz,  Firas Kobeissy,  Fouad A. Zouein, 
  • First Published: 20 July 2017
Research Article
Open Access

Associations between Specific Redox Biomarkers and Age in a Large European Cohort: The MARK-AGE Project

Daniela Weber,  Wolfgang Stuetz,  Olivier Toussaint,  Florence Debacq-Chainiaux,  Martijn E. T. Dollé,  Eugène Jansen,  Efstathios S. Gonos,  Claudio Franceschi,  Ewa Sikora,  Antti Hervonen,  Nicolle Breusing,  Thilo Sindlinger,  María Moreno-Villanueva,  Alexander Bürkle,  Tilman Grune, 
  • First Published: 19 July 2017
Research Article
Open Access

Combined Respiratory Chain Deficiency and UQCC2 Mutations in Neonatal Encephalomyopathy: Defective Supercomplex Assembly in Complex III Deficiencies

René G. Feichtinger,  Michaela Brunner-Krainz,  Bader Alhaddad,  Saskia B. Wortmann,  Reka Kovacs-Nagy,  Tatjana Stojakovic,  Wolfgang Erwa,  Bernhard Resch,  Werner Windischhofer,  Sarah Verheyen,  Sabine Uhrig,  Christian Windpassinger,  Felix Sternberg,  Christine Makowski,  Tim M. Strom,  Thomas Meitinger,  Holger Prokisch,  Wolfgang Sperl,  Tobias B. Haack,  Johannes A. Mayr, 
  • First Published: 19 July 2017
Research Article
Open Access

Hongjingtian Injection Attenuates Myocardial Oxidative Damage via Promoting Autophagy and Inhibiting Apoptosis

Shujing Zhang,  Ling Zhang,  Han Zhang,  Guanwei Fan,  Jiuwen Qiu,  Zongbao Fang,  Haibo Wu,  Yi Wang,  Xiaoping Zhao, 
  • First Published: 19 July 2017
Research Article
Open Access

In Vivo Radioprotective Activity of Cell-Permeable Bifunctional Antioxidant Enzyme GST-TAT-SOD against Whole-Body Ionizing Irradiation in Mice

Jianru Pan,  Huocong He,  Ying Su,  Guangjin Zheng,  Junxin Wu,  Shutao Liu,  Pingfan Rao, 
  • First Published: 19 July 2017
Research Article
Open Access

mTOR Inhibition Rejuvenates the Aging Gingival Fibroblasts through Alleviating Oxidative Stress

Yiru Xia,  Mengjun Sun,  Yufeng Xie,  Rong Shu, 
  • First Published: 19 July 2017
Research Article
Open Access

Overexpression of Brg1 Alleviates Hepatic Ischemia/Reperfusion-Induced Acute Lung Injury through Antioxidative Stress Effects

Mian Ge,  Chaojin Chen,  Weifeng Yao,  Shaoli Zhou,  Fei Huang,  Jun Cai,  Ziqing Hei, 
  • First Published: 16 July 2017
Research Article
Open Access

Amelioration of Abnormalities Associated with the Metabolic Syndrome by Spinacia oleracea (Spinach) Consumption and Aerobic Exercise in Rats

Vandana Panda,  Kinjal Mistry,  S. Sudhamani,  Mukesh Nandave,  Shreesh Kumar Ojha, 
  • First Published: 16 July 2017
Research Article
Open Access

REGγ Contributes to Regulation of Hemoglobin and Hemoglobin δ Subunit

Qiuhong Zuo,  Shanshan Cheng,  Wenxiang Huang,  Muhammad Zeeshan Bhatti,  Yanyan Xue,  Yuanyuan Zhang,  Bianhong Zhang,  Lei Li,  Lin Wu,  Junjiang Fu,  Jiwu Chen,  Xiaotao Li, 
  • First Published: 16 July 2017
Research Article
Open Access

ROS-Mediated Apoptosis and Genotoxicity Induced by Palladium Nanoparticles in Human Skin Malignant Melanoma Cells

Saud Alarifi,  Daoud Ali,  Saad Alkahtani,  Rafa S. Almeer, 
  • First Published: 16 July 2017
Review Article
Open Access

Neuroprotection of Catalpol for Experimental Acute Focal Ischemic Stroke: Preclinical Evidence and Possible Mechanisms of Antioxidation, Anti-Inflammation, and Antiapoptosis

Xia-wei Zheng,  Wen-ting Yang,  Shuang Chen,  Qing-qing Xu,  Chun-shuo Shan,  Guo-qing Zheng,  Ji-chen Ruan, 
  • First Published: 13 July 2017
Research Article
Open Access

Progression of Hepatic Adenoma to Carcinoma in Ogg1 Mutant Mice Induced by Phenobarbital

Anna Kakehashi,  Naomi Ishii,  Takahiro Okuno,  Masaki Fujioka,  Min Gi,  Shoji Fukushima,  Hideki Wanibuchi, 
  • First Published: 13 July 2017
Research Article
Open Access

Expression of the NRF2 Target Gene NQO1 Is Enhanced in Mononuclear Cells in Human Chronic Kidney Disease

Jianlin Shen,  Marianne Rasmussen,  Qi-Rong Dong,  Martin Tepel,  Alexandra Scholze, 
  • First Published: 13 July 2017
Review Article
Open Access

Antiobesity Effects of Anthocyanins in Preclinical and Clinical Studies

Elena Azzini,  Jasminka Giacometti,  Gian Luigi Russo, 
  • First Published: 13 July 2017
Review Article
Open Access

Disrupted Skeletal Muscle Mitochondrial Dynamics, Mitophagy, and Biogenesis during Cancer Cachexia: A Role for Inflammation

Brandon N. VanderVeen,  Dennis K. Fix,  James A. Carson, 
  • First Published: 13 July 2017
Research Article
Open Access

NADPH Oxidase 2 Regulates NLRP3 Inflammasome Activation in the Brain after Traumatic Brain Injury

Merry W. Ma,  Jing Wang,  Krishnan M. Dhandapani,  Darrell W. Brann, 
  • First Published: 12 July 2017
Review Article
Open Access

Ethanolamine and Phosphatidylethanolamine: Partners in Health and Disease

Dhaval Patel,  Stephan N. Witt, 
  • First Published: 12 July 2017
Research Article
Open Access

Ginkgolide B Suppresses TLR4-Mediated Inflammatory Response by Inhibiting the Phosphorylation of JAK2/STAT3 and p38 MAPK in High Glucose-Treated HUVECs

Kun Chen,  Wenjia Sun,  Yun Jiang,  Beidong Chen,  Yanyang Zhao,  Jie Sun,  Huan Gong,  Ruomei Qi, 
  • First Published: 12 July 2017
Research Article
Open Access

Effect of Content of Sulfate Groups in Seaweed Polysaccharides on Antioxidant Activity and Repair Effect of Subcellular Organelles in Injured HK-2 Cells

Xiao-Tao Ma,  Xin-Yuan Sun,  Kai Yu,  Bao-Song Gui,  Qin Gui,  Jian-Ming Ouyang, 
  • First Published: 12 July 2017
Review Article
Open Access

Oxidative Stress in Neurodegenerative Diseases: From Molecular Mechanisms to Clinical Applications

Zewen Liu,  Tingyang Zhou,  Alexander C. Ziegler,  Peter Dimitrion,  Li Zuo, 
  • First Published: 12 July 2017
Research Article
Open Access

Mitochondrial Respiration in Human Colorectal and Breast Cancer Clinical Material Is Regulated Differently

Andre Koit,  Igor Shevchuk,  Lyudmila Ounpuu,  Aleksandr Klepinin,  Vladimir Chekulayev,  Natalja Timohhina,  Kersti Tepp,  Marju Puurand,  Laura Truu,  Karoliina Heck,  Vahur Valvere,  Rita Guzun,  Tuuli Kaambre, 
  • First Published: 11 July 2017
Research Article
Open Access

The Effects of Diabetes Induction on the Rat Heart: Differences in Oxidative Stress, Inflammatory Cells, and Fibrosis between Subendocardial and Interstitial Myocardial Areas

Maria C. Guido,  Alyne F. Marques,  Elaine R. Tavares,  Marcelo D. Tavares de Melo,  Vera M. C. Salemi,  Raul C. Maranhão, 
  • First Published: 11 July 2017
Editorial
Open Access

mTOR Signaling in Cardiometabolic Disease, Cancer, and Aging

Anindita Das,  Flávio Reis,  Yasuhiro Maejima,  Zhiyou Cai,  Jun Ren, 
  • First Published: 10 July 2017
Research Article
Open Access

Cardioprotective Effect of Selective Estrogen Receptor Modulator Raloxifene Are Mediated by Heme Oxygenase in Estrogen-Deficient Rat

Anikó Posa,  Renáta Szabó,  Krisztina Kupai,  Anikó Magyariné Berkó,  Médea Veszelka,  Gergő Szűcs,  Denise Börzsei,  Mariann Gyöngyösi,  Imre Pávó,  Zoltán Deim,  Zoltán Szilvássy,  Béla Juhász,  Csaba Varga, 
  • First Published: 09 July 2017
Research Article
Open Access

Brain-Derived Neurotrophic Factor Attenuates Septic Myocardial Dysfunction via eNOS/NO Pathway in Rats

Ni Zeng,  Junmei Xu,  Weifeng Yao,  Suobei Li,  Wei Ruan,  Feng Xiao, 
  • First Published: 09 July 2017
Review Article
Open Access

Effects of Antioxidant Supplements on the Survival and Differentiation of Stem Cells

Sara Shaban,  Mostafa Wanees Ahmed El-Husseny,  Abdelrahman Ibrahim Abushouk,  Amr Muhammad Abdo Salem,  Mediana Mamdouh,  Mohamed M. Abdel-Daim, 
  • First Published: 09 July 2017
Research Article
Open Access

Metformin and Its Sulfenamide Prodrugs Inhibit Human Cholinesterase Activity

Magdalena Markowicz-Piasecka,  Joanna Sikora,  Łukasz Mateusiak,  Elżbieta Mikiciuk-Olasik,  Kristiina M. Huttunen, 
  • First Published: 09 July 2017
Research Article
Open Access

Neuroprotective and Memory-Enhancing Effect of the Combined Extract of Purple Waxy Corn Cob and Pandan in Ovariectomized Rats

Woranan Kirisattayakul,  Jintanaporn Wattanathorn,  Sittichai Iamsaard,  Jinatta Jittiwat,  Bhalang Suriharn,  Kamol Lertrat, 
  • First Published: 09 July 2017
Review Article
Open Access

Oxidative Stress Gene Expression Profile Correlates with Cancer Patient Poor Prognosis: Identification of Crucial Pathways Might Select Novel Therapeutic Approaches

Alessandra Leone,  Maria Serena Roca,  Chiara Ciardiello,  Susan Costantini,  Alfredo Budillon, 
  • First Published: 09 July 2017
Research Article
Open Access

Pitaya Extracts Induce Growth Inhibition and Proapoptotic Effects on Human Cell Lines of Breast Cancer via Downregulation of Estrogen Receptor Gene Expression

Deborah de Almeida Bauer Guimarães,  Danielle dos Santos Bonfim De Castro,  Felipe Leite de Oliveira,  Eduardo Matos Nogueira,  Marco Antônio Mota da Silva,  Anderson Junger Teodoro, 
  • First Published: 06 July 2017
Research Article
Open Access

Flavonoids as Putative Inducers of the Transcription Factors Nrf2, FoxO, and PPARγ

Kathrin Pallauf,  Nils Duckstein,  Mario Hasler,  Lars-Oliver Klotz,  Gerald Rimbach, 
  • First Published: 06 July 2017
Research Article
Open Access

Mitochondria-Targeted Antioxidant SkQ1 Improves Dermal Wound Healing in Genetically Diabetic Mice

Ilya A. Demyanenko,  Vlada V. Zakharova,  Olga P. Ilyinskaya,  Tamara V. Vasilieva,  Artem V. Fedorov,  Vasily N. Manskikh,  Roman A. Zinovkin,  Olga Yu Pletjushkina,  Boris V. Chernyak,  Vladimir P. Skulachev,  Ekaterina N. Popova, 
  • First Published: 06 July 2017
Research Article
Open Access

Baicalin Ameliorates Experimental Liver Cholestasis in Mice by Modulation of Oxidative Stress, Inflammation, and NRF2 Transcription Factor

Kezhen Shen,  Xiaowen Feng,  Hao Pan,  Feng Zhang,  Haiyang Xie,  Shusen Zheng, 
  • First Published: 05 July 2017
Research Article
Open Access

Curcumin Protects Skin against UVB-Induced Cytotoxicity via the Keap1-Nrf2 Pathway: The Use of a Microemulsion Delivery System

Maya Ben Yehuda Greenwald,  Marina Frušić-Zlotkin,  Yoram Soroka,  Shmuel Ben Sasson,  Ronit Bitton,  Havazelet Bianco-Peled,  Ron Kohen, 
  • First Published: 05 July 2017
Review Article
Open Access

The Involvement of Mg2+ in Regulation of Cellular and Mitochondrial Functions

Ivana Pilchova,  Katarina Klacanova,  Zuzana Tatarkova,  Peter Kaplan,  Peter Racay, 
  • First Published: 05 July 2017
Research Article
Open Access

Metabolic Reprogramming, Autophagy, and Reactive Oxygen Species Are Necessary for Primordial Germ Cell Reprogramming into Pluripotency

D. Sainz de la Maza,  A. Moratilla,  V. Aparicio,  C. Lorca,  Y. Alcaina,  D. Martín,  M. P. De Miguel, 
  • First Published: 05 July 2017
Review Article
Open Access

Lysosomes as Oxidative Targets for Cancer Therapy

Rebecca F. Dielschneider,  Elizabeth S. Henson,  Spencer B. Gibson, 
  • First Published: 05 July 2017
Clinical Study
Open Access

Lung-Protective Ventilation Strategies for Relief from Ventilator-Associated Lung Injury in Patients Undergoing Craniotomy: A Bicenter Randomized, Parallel, and Controlled Trial

Chaoliang Tang,  Juan Li,  Shaoqing Lei,  Bo Zhao,  Zhetao Zhang,  Wenting Huang,  Si Shi,  Xiaoqing Chai,  Chaoshi Niu,  Zhongyuan Xia, 
  • First Published: 05 July 2017
Review Article
Open Access

Does Regular Exercise Counter T Cell Immunosenescence Reducing the Risk of Developing Cancer and Promoting Successful Treatment of Malignancies?

James E. Turner,  Patricia C. Brum, 
  • First Published: 02 July 2017
Research Article
Open Access

Effects of Redox Modulation on Cell Proliferation, Viability, and Migration in Cultured Rat and Human Tendon Progenitor Cells

Yuk Wa Lee,  Sai Chuen Fu,  Man Yi Yeung,  Chun Man Lawrence Lau,  Kai Ming Chan,  Leung Kim Hung, 
  • First Published: 02 July 2017
Research Article
Open Access

Maresin 1 Ameliorates Lung Ischemia/Reperfusion Injury by Suppressing Oxidative Stress via Activation of the Nrf-2-Mediated HO-1 Signaling Pathway

Quanchao Sun,  You Wu,  Feng Zhao,  Jianjun Wang, 
  • First Published: 02 July 2017
Research Article
Open Access

The Preconditioning of Berberine Suppresses Hydrogen Peroxide-Induced Premature Senescence via Regulation of Sirtuin 1

Xiaofei Zhu,  Haodi Yue,  Xiaofang Guo,  Jingyi Yang,  Jingshuo Liu,  Jiangtao Liu,  Ruijie Wang,  Wenjuan Zhu, 
  • First Published: 02 July 2017
Review Article
Open Access

The Central Role of Biometals Maintains Oxidative Balance in the Context of Metabolic and Neurodegenerative Disorders

Michal Pokusa,  Alžbeta Kráľová Trančíková, 
  • First Published: 02 July 2017
Review Article
Open Access

A Review of the Molecular Mechanisms Underlying the Development and Progression of Cardiac Remodeling

Leonardo Schirone,  Maurizio Forte,  Silvia Palmerio,  Derek Yee,  Cristina Nocella,  Francesco Angelini,  Francesca Pagano,  Sonia Schiavon,  Antonella Bordin,  Albino Carrizzo,  Carmine Vecchione,  Valentina Valenti,  Isotta Chimenti,  Elena De Falco,  Sebastiano Sciarretta,  Giacomo Frati, 
  • First Published: 02 July 2017
Research Article
Open Access

The Correlation between Chemical Structures and Antioxidant, Prooxidant, and Antitrypanosomatid Properties of Flavonoids

João Luiz Baldim,  Bianca Gonçalves Vasconcelos de Alcântara,  Olívia da Silva Domingos,  Marisi Gomes Soares,  Ivo Santana Caldas,  Rômulo Dias Novaes,  Tiago Branquinho Oliveira,  João Henrique Ghilardi Lago,  Daniela Aparecida Chagas-Paula, 
  • First Published: 02 July 2017
Research Article
Open Access

Oxidative Phosphorylation System in Gastric Carcinomas and Gastritis

René G. Feichtinger,  Daniel Neureiter,  Tom Skaria,  Silja Wessler,  Timothy L. Cover,  Johannes A. Mayr,  Franz A. Zimmermann,  Gernot Posselt,  Wolfgang Sperl,  Barbara Kofler, 
  • First Published: 28 June 2017
Research Article
Open Access

Commiphora molmol Modulates Glutamate-Nitric Oxide-cGMP and Nrf2/ARE/HO-1 Pathways and Attenuates Oxidative Stress and Hematological Alterations in Hyperammonemic Rats

Ayman M. Mahmoud,  Sultan Alqahtani,  Sarah I. Othman,  Mousa O. Germoush,  Omnia E. Hussein,  Gadh Al-Basher,  Jong Seong Khim,  Maha A. Al-Qaraawi,  Hanan M. Al-Harbi,  Abdulmannan Fadel,  Ahmed A. Allam, 
  • First Published: 28 June 2017
Review Article
Open Access

Role of Kallistatin Treatment in Aging and Cancer by Modulating miR-34a and miR-21 Expression

Julie Chao,  Youming Guo,  Pengfei Li,  Lee Chao, 
  • First Published: 28 June 2017
Review Article
Open Access

Pathomechanisms of Oxidative Stress in Inflammatory Bowel Disease and Potential Antioxidant Therapies

Tian Tian,  Ziling Wang,  Jinhua Zhang, 
  • First Published: 28 June 2017
Research Article
Open Access

Effect of Cocoa Polyphenolic Extract on Macrophage Polarization from Proinflammatory M1 to Anti-Inflammatory M2 State

Laura Dugo,  Maria Giovanna Belluomo,  Chiara Fanali,  Marina Russo,  Francesco Cacciola,  Mauro Maccarrone,  Anna Maria Sardanelli, 
  • First Published: 28 June 2017
Research Article
Open Access

Effect of Whole-Body Cryotherapy on Antioxidant Systems in Experimental Rat Model

Bronisława Skrzep-Poloczek,  Ewa Romuk,  Bernadeta Wiśnowiska,  Aleksander J. Owczarek,  Piotr Choręza,  Aleksander Sieroń,  Ewa Birkner,  Dominika Stygar, 
  • First Published: 27 June 2017
Research Article
Open Access

Methane Suppresses Microglial Activation Related to Oxidative, Inflammatory, and Apoptotic Injury during Spinal Cord Injury in Rats

WeiHeng Wang,  Xiaodong Huang,  Jian Li,  Aijun Sun,  Jiangming Yu,  Ning Xie,  YanHai Xi,  Xiaojian Ye, 
  • First Published: 27 June 2017
Research Article
Open Access

Toxicity and Immunogenicity in Murine Melanoma following Exposure to Physical Plasma-Derived Oxidants

Sander Bekeschus,  Katrin Rödder,  Bob Fregin,  Oliver Otto,  Maxi Lippert,  Klaus-Dieter Weltmann,  Kristian Wende,  Anke Schmidt,  Rajesh Kumar Gandhirajan, 
  • First Published: 27 June 2017
Research Article
Open Access

Quercetin Reverses Rat Liver Preneoplastic Lesions Induced by Chemical Carcinogenesis

Gabriela Carrasco-Torres,  Hugo Christian Monroy-Ramírez,  Arturo Axayacatl Martínez-Guerra,  Rafael Baltiérrez-Hoyos,  María de los Ángeles Romero-Tlalolini,  Saúl Villa-Treviño,  Xariss Sánchez-Chino,  Verónica Rocío Vásquez-Garzón, 
  • First Published: 27 June 2017
Review Article
Open Access

DNA Oncogenic Virus-Induced Oxidative Stress, Genomic Damage, and Aberrant Epigenetic Alterations

Mankgopo Magdeline Kgatle,  Catherine Wendy Spearman,  Asgar Ali Kalla,  Henry Norman Hairwadzi, 
  • First Published: 27 June 2017
Research Article
Open Access

Comparison of the Neuroprotective and Anti-Inflammatory Effects of the Anthocyanin Metabolites, Protocatechuic Acid and 4-Hydroxybenzoic Acid

Aimee N. Winter,  Matthew C. Brenner,  Noelle Punessen,  Michael Snodgrass,  Caleb Byars,  Yingyot Arora,  Daniel A. Linseman, 
  • First Published: 27 June 2017
Research Article
Open Access

Influence of the Microstructure and Silver Content on Degradation, Cytocompatibility, and Antibacterial Properties of Magnesium-Silver Alloys In Vitro

Zhidan Liu,  Ronald Schade,  Bérengère Luthringer,  Norbert Hort,  Holger Rothe,  Sören Müller,  Klaus Liefeith,  Regine Willumeit-Römer,  Frank Feyerabend, 
  • First Published: 22 June 2017
Research Article
Open Access

Fish Scale Collagen Peptides Protect against CoCl2/TNF-α-Induced Cytotoxicity and Inflammation via Inhibition of ROS, MAPK, and NF-κB Pathways in HaCaT Cells

Fazli Subhan,  Hae Yeong Kang,  Yeseon Lim,  Muhammad Ikram,  Sun-Yong Baek,  Songwan Jin,  Young Hun Jeong,  Jong Young Kwak,  Sik Yoon, 
  • First Published: 22 June 2017
Research Article
Open Access

SIRT3 Enhances Mesenchymal Stem Cell Longevity and Differentiation

Ryan A. Denu, 
  • First Published: 21 June 2017
Research Article
Open Access

The Treadmill Exercise Protects against Dopaminergic Neuron Loss and Brain Oxidative Stress in Parkinsonian Rats

Roberta Oliveira da Costa,  Carlos Vinicius Jataí Gadelha-Filho,  Ayane Edwiges Moura da Costa,  Mariana Lima Feitosa,  Dayane Pessoa de Araújo,  Jalles Dantas de Lucena,  Pedro Everson Alexandre de Aquino,  Francisco Arnaldo Viana Lima,  Kelly Rose Tavares Neves,  Glauce Socorro de Barros Viana, 
  • First Published: 21 June 2017

Research Article
Open Access

Comparative Therapeutic Effects of Minocycline Treatment and Bone Marrow Mononuclear Cell Transplantation following Striatal Stroke

Celice C. Souza,  Michelle Castro da Silva,  Rosana Telma Lopes,  Marcelo M. Cardoso,  Lucas Lacerda de Souza,  Adriano Guimarães Santos,  Ijair Rogério dos Santos,  Edna C. S. Franco,  Walace Gomes-Leal, 
  • First Published: 21 June 2017
Research Article
Open Access

Mulberry Anthocyanin Extract Ameliorates Oxidative Damage in HepG2 Cells and Prolongs the Lifespan of Caenorhabditis elegans through MAPK and Nrf2 Pathways

Fujie Yan,  Yushu Chen,  Ramila Azat,  Xiaodong Zheng, 
  • First Published: 21 June 2017
Research Article
Open Access

Picroside II Shows Protective Functions for Severe Acute Pancreatitis in Rats by Preventing NF-κB-Dependent Autophagy

Xuehua Piao,  Baohai Liu,  Lianyi Guo,  Fanji Meng,  Leming Gao, 
  • First Published: 21 June 2017
Research Article
Open Access

Moderate Autophagy Inhibits Vascular Smooth Muscle Cell Senescence to Stabilize Progressed Atherosclerotic Plaque via the mTORC1/ULK1/ATG13 Signal Pathway

Zhenli Luo,  Wenhuan Xu,  Sai Ma,  Hongyu Qiao,  Lei Gao,  Ran Zhang,  Bo Yang,  Ya Qiu,  Jiangwei Chen,  Ming Zhang,  Bo Tao,  Feng Cao,  Yabin Wang, 
  • First Published: 21 June 2017
Review Article
Open Access

Salvianolic Acid Exerts Cardioprotection through Promoting Angiogenesis in Animal Models of Acute Myocardial Infarction: Preclinical Evidence

Long-jie Yu,  Ke-Jian Zhang,  Jia-Zhen Zhu,  Qun Zheng,  Xiao-Yi Bao,  Saroj Thapa,  Yan Wang,  Mao-Ping Chu, 
  • First Published: 21 June 2017
Research Article
Open Access

Concurrent Aerobic and Resistance Training Has Anti-Inflammatory Effects and Increases Both Plasma and Leukocyte Levels of IGF-1 in Late Middle-Aged Type 2 Diabetic Patients

Giosuè Annibalini,  Francesco Lucertini,  Deborah Agostini,  Luciana Vallorani,  Annamaria Gioacchini,  Elena Barbieri,  Michele Guescini,  Lucia Casadei,  Annunziata Passalia,  Marta Del Sal,  Giovanni Piccoli,  Mauro Andreani,  Ario Federici,  Vilberto Stocchi, 
  • First Published: 21 June 2017
Review Article
Open Access

MicroRNAs and Autophagy: Fine Players in the Control of Chondrocyte Homeostatic Activities in Osteoarthritis

Stefania D’Adamo,  Silvia Cetrullo,  Manuela Minguzzi,  Ylenia Silvestri,  Rosa Maria Borzì,  Flavio Flamigni, 
  • First Published: 21 June 2017
Research Article
Open Access

Dietary Polyphenol Intake, but Not the Dietary Total Antioxidant Capacity, Is Inversely Related to Cardiovascular Disease in Postmenopausal Polish Women: Results of WOBASZ and WOBASZ II Studies

Anna M. Witkowska,  Anna Waśkiewicz,  Małgorzata E. Zujko,  Danuta Szcześniewska,  Andrzej Pająk,  Urszula Stepaniak,  Wojciech Drygas, 
  • First Published: 20 June 2017
Research Article
Open Access

Myricitrin Modulates NADPH Oxidase-Dependent ROS Production to Inhibit Endotoxin-Mediated Inflammation by Blocking the JAK/STAT1 and NOX2/p47phox Pathways

Shimei Qi,  Zunyong Feng,  Qiang Li,  Zhilin Qi,  Yao Zhang, 
  • First Published: 20 June 2017
Research Article
Open Access

Moringa oleifera Seeds Attenuate Vascular Oxidative and Nitrosative Stresses in Spontaneously Hypertensive Rats

Joseph Iharinjaka Randriamboavonjy,  Marc Rio,  Pierre Pacaud,  Gervaise Loirand,  Angela Tesse, 
  • First Published: 20 June 2017
Research Article
Open Access

The Inhibitory Effect of WenxinKeli on H9C2 Cardiomyocytes Hypertrophy Induced by Angiotensin II through Regulating Autophagy Activity

Jie Li,  Yang Li,  Ying Zhang,  Dan Hu,  Yonghong Gao,  Hongcai Shang,  Yanwei Xing, 
  • First Published: 20 June 2017
Review Article
Open Access

Targeting Endothelial Function to Treat Heart Failure with Preserved Ejection Fraction: The Promise of Exercise Training

Andreas B. Gevaert,  Katrien Lemmens,  Christiaan J. Vrints,  Emeline M. Van Craenenbroeck, 
  • First Published: 19 June 2017
Research Article
Open Access

A Decrease of Brain MicroRNA-122 Level Is an Early Marker of Cerebrovascular Disease in the Stroke-Prone Spontaneously Hypertensive Rat

Rosita Stanzione,  Franca Bianchi,  Maria Cotugno,  Simona Marchitti,  Maurizio Forte,  Carla Busceti,  Larisa Ryskalin,  Francesco Fornai,  Massimo Volpe,  Speranza Rubattu, 
  • First Published: 18 June 2017
Research Article
Open Access

Apple Flavonoids Suppress Carcinogen-Induced DNA Damage in Normal Human Bronchial Epithelial Cells

Vazhappilly Cijo George,  H. P. Vasantha Rupasinghe, 
  • First Published: 18 June 2017
Research Article
Open Access

Modulatory Effect of Monochromatic Blue Light on Heat Stress Response in Commercial Broilers

Safaa E. Abdo,  Seham El-Kassas,  Abeer F. El-Nahas,  Shawky Mahmoud, 
  • First Published: 18 June 2017
Research Article
Open Access

High-Intensity Exercise Reduces Cardiac Fibrosis and Hypertrophy but Does Not Restore the Nitroso-Redox Imbalance in Diabetic Cardiomyopathy

Ulises Novoa,  Diego Arauna,  Marisol Moran,  Madelaine Nuñez,  Sebastián Zagmutt,  Sergio Saldivia,  Cristian Valdes,  Jorge Villaseñor,  Carmen Gloria Zambrano,  Daniel R. Gonzalez, 
  • First Published: 18 June 2017
Review Article
Open Access

Reactive Oxygen Species-Mediated Mechanisms of Action of Targeted Cancer Therapy

Hanna-Riikka Teppo,  Ylermi Soini,  Peeter Karihtala, 
  • First Published: 18 June 2017
Research Article
Open Access

NRF2 Plays a Critical Role in Both Self and EGCG Protection against Diabetic Testicular Damage

Chenyu Pan,  Shengzhu Zhou,  Junduo Wu,  Lingyun Liu,  Yanyan Song,  Tie Li,  Lijuan Ha,  Xiaona Liu,  Fuchun Wang,  Jingyan Tian,  Hao Wu, 
  • First Published: 18 June 2017
Review Article
Open Access

Measurement and Clinical Significance of Biomarkers of Oxidative Stress in Humans

Ilaria Marrocco,  Fabio Altieri,  Ilaria Peluso, 
  • First Published: 18 June 2017
Research Article
Open Access

Adherence to the Mediterranean Diet and Circulating Levels of Sirtuin 4 in Obese Patients: A Novel Association

Luigi Barrea,  Giovanni Tarantino,  Carolina Di Somma,  Giovanna Muscogiuri,  Paolo Emidio Macchia,  Andrea Falco,  Annamaria Colao,  Silvia Savastano, 
  • First Published: 15 June 2017
Research Article
Open Access

Neuronal Damage Induced by Perinatal Asphyxia Is Attenuated by Postinjury Glutaredoxin-2 Administration

Juan Ignacio Romero,  Mariana Inés Holubiec,  Tamara Logica Tornatore,  Stéphanie Rivière,  Eva-Maria Hanschmann,  Rodolfo Alberto Kölliker-Frers,  Julia Tau,  Eduardo Blanco,  Pablo Galeano,  Fernando Rodríguez de Fonseca,  Christopher Horst Lillig,  Francisco Capani, 
  • First Published: 15 June 2017
Research Article
Open Access

Risperidone-Induced Renal Damage and Metabolic Side Effects: The Protective Effect of Resveratrol

Sedat Bilgiç,  Deniz Taştemir Korkmaz,  Sebile Azirak,  Ayşe Nilay Güvenç,  Nevin Kocaman,  Mehmet Kaya Özer, 
  • First Published: 15 June 2017
Research Article
Open Access

The Role of Free Radicals in Hemolytic Toxicity Induced by Atmospheric-Pressure Plasma Jet

Ku Youn Baik,  Yoon Ho Huh,  Yong Hee Kim,  Jeongho Kim,  Min Su Kim,  Hun-Kuk Park,  Eun Ha Choi,  Byoungchoo Park, 
  • First Published: 14 June 2017
Review Article
Open Access

Omega-3 Polyunsaturated Fatty Acids in Critical Illness: Anti-Inflammatory, Proresolving, or Both?

Alessio Molfino,  Maria Ida Amabile,  Massimo Monti,  Maurizio Muscaritoli, 
  • First Published: 14 June 2017
Research Article
Open Access

Heme Oxygenase-1, a Key Enzyme for the Cytoprotective Actions of Halophenols by Upregulating Nrf2 Expression via Activating Erk1/2 and PI3K/Akt in EA.hy926 Cells

Xiu E. Feng,  Tai Gang Liang,  Jie Gao,  De Peng Kong,  Rui Ge,  Qing Shan Li, 
  • First Published: 14 June 2017
Research Article
Open Access

The Protective Effect of Indole-3-Acetic Acid (IAA) on H2O2-Damaged Human Dental Pulp Stem Cells Is Mediated by the AKT Pathway and Involves Increased Expression of the Transcription Factor Nuclear Factor-Erythroid 2-Related Factor 2 (Nrf2) and Its Downstream Target Heme Oxygenase 1 (HO-1)

Daehwan Kim,  Hyewon Kim,  Kichul Kim,  Sangho Roh, 
  • First Published: 14 June 2017
Research Article
Open Access

Novel Therapeutic Effects of Leonurine On Ischemic Stroke: New Mechanisms of BBB Integrity

Qiu-Yan Zhang,  Zhi-Jun Wang,  De-Miao Sun,  Ying Wang,  Peng Xu,  Wei-Jun Wu,  Xin-Hua Liu,  Yi-Zhun Zhu, 
  • First Published: 13 June 2017
Review Article
Open Access

Are Antioxidants a Potential Therapy for FSHD? A Review of the Literature

Adam Philip Denny,  Alison Kay Heather, 
  • First Published: 12 June 2017
Research Article
Open Access

Tanshinone IIA Inhibits Glutamate-Induced Oxidative Toxicity through Prevention of Mitochondrial Dysfunction and Suppression of MAPK Activation in SH-SY5Y Human Neuroblastoma Cells

Haifeng Li,  Wenjing Han,  Hongyu Wang,  Fei Ding,  Lingyun Xiao,  Ruona Shi,  Liping Ai,  Zebo Huang, 
  • First Published: 11 June 2017
Review Article
Open Access

Sestrin2 as a Novel Biomarker and Therapeutic Target for Various Diseases

Mazhar Pasha,  Ali H. Eid,  Assaad A. Eid,  Yves Gorin,  Shankar Munusamy, 
  • First Published: 11 June 2017
Research Article
Open Access

Lycium barbarum Reduces Abdominal Fat and Improves Lipid Profile and Antioxidant Status in Patients with Metabolic Syndrome

Mayara Zagonel de Souza Zanchet,  Geisson Marcos Nardi,  Letícia de Oliveira Souza Bratti,  Fabíola Branco Filippin-Monteiro,  Claudriana Locatelli, 
  • First Published: 08 June 2017
Research Article
Open Access

Hydrogen Sulfide Inhibits Autophagic Neuronal Cell Death by Reducing Oxidative Stress in Spinal Cord Ischemia Reperfusion Injury

Lei Xie,  Sifei Yu,  Kai Yang,  Changwei Li,  Yu Liang, 
  • First Published: 08 June 2017
Research Article
Open Access

Activation of p47phox as a Mechanism of Bupivacaine-Induced Burst Production of Reactive Oxygen Species and Neural Toxicity

Yu-jie Li,  Wei Zhao,  Xu-jiao Yu,  Feng-xian Li,  Zi-ting Liu,  Le Li,  Shi-yuan Xu, 
  • First Published: 08 June 2017
Research Article
Open Access

Methylglyoxal Induces Changes in the Glyoxalase System and Impairs Glutamate Uptake Activity in Primary Astrocytes

Fernanda Hansen,  Fabiana Galland,  Franciane Lirio,  Daniela Fraga de Souza,  Carollina Da Ré,  Rafaela Ferreira Pacheco,  Adriana Fernanda Vizuete,  André Quincozes-Santos,  Marina Concli Leite,  Carlos-Alberto Gonçalves, 
  • First Published: 08 June 2017
Review Article
Open Access

MNRR1, a Biorganellar Regulator of Mitochondria

Lawrence I. Grossman,  Neeraja Purandare,  Rooshan Arshad,  Stephanie Gladyck,  Mallika Somayajulu,  Maik Hüttemann,  Siddhesh Aras, 
  • First Published: 08 June 2017
Research Article
Open Access

miR-Let7A Controls the Cell Death and Tight Junction Density of Brain Endothelial Cells under High Glucose Condition

Juhyun Song,  So Ra Yoon,  Oh Yoen Kim, 
  • First Published: 07 June 2017
Review Article
Open Access

Mitochondrial Nucleoid: Shield and Switch of the Mitochondrial Genome

Sung Ryul Lee,  Jin Han, 
  • First Published: 07 June 2017
Research Article
Open Access

Chk1 Promotes DNA Damage Response Bypass following Oxidative Stress in a Model of Hydrogen Peroxide-Associated Ulcerative Colitis through JNK Inactivation and Chromatin Binding

Kathrin Reissig,  Andrew Silver,  Roland Hartig,  Antje Schinlauer,  Diana Walluscheck,  Thomas Guenther,  Sandra Siedentopf,  Jochen Ross,  Diep-Khanh Vo,  Albert Roessner,  Angela Poehlmann-Nitsche, 
  • First Published: 07 June 2017
Research Article
Open Access

Mitochondrial Uncoupler Prodrug of 2,4-Dinitrophenol, MP201, Prevents Neuronal Damage and Preserves Vision in Experimental Optic Neuritis

Reas S. Khan,  Kimberly Dine,  John G. Geisler,  Kenneth S. Shindler, 
  • First Published: 07 June 2017
Research Article
Open Access

miR-382 Contributes to Renal Tubulointerstitial Fibrosis by Downregulating HSPD1

Yi Fang,  Ting Xie,  Ning Xue,  Qing Kuang,  Zheng Wei,  Mingyu Liang,  Xiaoqiang Ding, 
  • First Published: 07 June 2017
Research Article
Open Access

Protective Effect of Icariin on the Development of Preimplantation Mouse Embryos against Hydrogen Peroxide-Induced Oxidative Injury

Rong Ye,  Songhua Xu,  Yue Liu,  Lili Pang,  Xiuli Lian,  Yuhuan Zhong,  Yang Su,  Shie Wang, 
  • First Published: 07 June 2017
Research Article
Open Access

Genetic Nrf2 Overactivation Inhibits the Deleterious Effects Induced by Hepatocyte-Specific c-met Deletion during the Progression of NASH

Pierluigi Ramadori,  Hannah Drescher,  Stephanie Erschfeld,  Athanassios Fragoulis,  Thomas W. Kensler,  Christoph Jan Wruck,  Francisco Javier Cubero,  Christian Trautwein,  Konrad L. Streetz,  Daniela C. Kroy, 
  • First Published: 06 June 2017
Research Article
Open Access

Assessing Free-Radical-Mediated DNA Damage during Cardiac Surgery: 8-Oxo-7,8-dihydro-2′-deoxyguanosine as a Putative Biomarker

Linda Turnu,  Alessandro Di Minno,  Benedetta Porro,  Isabella Squellerio,  Alice Bonomi,  Chiara Maria Manega,  José Pablo Werba,  Alessandro Parolari,  Elena Tremoli,  Viviana Cavalca, 
  • First Published: 04 June 2017
Research Article
Open Access

Paradoxical Effect of Nonalcoholic Red Wine Polyphenol Extract, Provinols™, in the Regulation of Cyclooxygenases in Vessels from Zucker Fatty Rats (fa/fa)

Abdelali Agouni,  Hadj Ahmed Mostefai,  Anne-Hélène Lagrue,  Martina Sladkova,  Philippe Rouet,  Franck Desmoulin,  Olga Pechanova,  Maria Carmen Martínez,  Ramaroson Andriantsitohaina, 
  • First Published: 04 June 2017
Research Article
Open Access

MicroRNAs Modulate Oxidative Stress in Hypertension through PARP-1 Regulation

Douglas F. Dluzen,  Yoonseo Kim,  Paul Bastian,  Yongqing Zhang,  Elin Lehrmann,  Kevin G. Becker,  Nicole Noren Hooten,  Michele K. Evans, 
  • First Published: 04 June 2017
Research Article
Open Access

Neutrophil and Monocyte Bactericidal Responses to 10 Weeks of Low-Volume High-Intensity Interval or Moderate-Intensity Continuous Training in Sedentary Adults

David B. Bartlett,  Sam O. Shepherd,  Oliver J. Wilson,  Ahmed M. Adlan,  Anton J. M. Wagenmakers,  Christopher S. Shaw,  Janet M. Lord, 
  • First Published: 01 June 2017
Review Article
Open Access

Impact of Aging and Exercise on Mitochondrial Quality Control in Skeletal Muscle

Yuho Kim,  Matthew Triolo,  David A. Hood, 
  • First Published: 01 June 2017
Research Article
Open Access

Association of the Composite Inflammatory Biomarker GlycA, with Exercise-Induced Changes in Body Habitus in Men and Women with Prediabetes

David B. Bartlett,  Cris A. Slentz,  Margery A. Connelly,  Lucy W. Piner,  Leslie H. Willis,  Lori A. Bateman,  Esther O. Granville,  Connie W. Bales,  Kim M. Huffman,  William E. Kraus, 
  • First Published: 31 May 2017
Corrigendum
Open Access

Corrigendum to “Plant-Derived Antioxidants in Disease Prevention”

Renata Szymanska,  Pavel Pospisil,  Jerzy Kruk, 
  • First Published: 31 May 2017

Research Article
Open Access

The Antioxidant Machinery of Young and Senescent Human Umbilical Vein Endothelial Cells and Their Microvesicles

Guillermo Bodega,  Matilde Alique,  Lourdes Bohórquez,  Sergio Ciordia,  María C. Mena,  Manuel R. Ramírez, 
  • First Published: 31 May 2017
Research Article
Open Access

LC-QTOF-MS Analysis and Activity Profiles of Popular Antioxidant Dietary Supplements in Terms of Quality Control

Elwira Sieniawska,  Tomasz Baj,  Rafal Sawicki,  Aleksandra Wanat,  Krzysztof Kamil Wojtanowski,  Grazyna Ginalska,  Grazyna Zgorka,  Jolanta Szymanska, 
  • First Published: 31 May 2017
Clinical Study
Open Access

Actinidia chinensis Planch. Improves the Indices of Antioxidant and Anti-Inflammation Status of Type 2 Diabetes Mellitus by Activating Keap1 and Nrf2 via the Upregulation of MicroRNA-424

Longfeng Sun,  Xiaofei Li,  Gang Li,  Bing Dai,  Wei Tan, 
  • First Published: 31 May 2017
Corrigendum
Open Access

Corrigendum to “Association of Nuclear Factor-Erythroid 2-Related Factor 2, Thioredoxin Interacting Protein, and Heme Oxygenase-1 Gene Polymorphisms with Diabetes and Obesity in Mexican Patients”

Angélica Saraí Jiménez-Osorio,  Susana González-Reyes,  Wylly Ramsés García-Niño,  Hortensia Moreno-Macías,  Martha Eunice Rodríguez-Arellano,  Gilberto Vargas-Alarcón,  Joaquín Zúñiga,  Rodrigo Barquera,  José Pedraza-Chaverri,  Juan Pablo Meza-Espinoza,  Evelia Leal-Ugarte,  Valeria Peralta-Leal, 
  • First Published: 30 May 2017

Review Article
Open Access

Evidence of Mitochondrial Dysfunction in Autism: Biochemical Links, Genetic-Based Associations, and Non-Energy-Related Mechanisms

Keren K. Griffiths,  Richard J. Levy, 
  • First Published: 29 May 2017
Research Article
Open Access

Homocysteine Induces Apoptosis of Human Umbilical Vein Endothelial Cells via Mitochondrial Dysfunction and Endoplasmic Reticulum Stress

Zhimin Zhang,  Congying Wei,  Yanfen Zhou,  Tao Yan,  Zhengqiang Wang,  Wei Li,  Lianyou Zhao, 
  • First Published: 28 May 2017
Research Article
Open Access

NPC-EXs Alleviate Endothelial Oxidative Stress and Dysfunction through the miR-210 Downstream Nox2 and VEGFR2 Pathways

Hua Liu,  Jinju Wang,  Yusen Chen,  Yanfang Chen,  Xiaotang Ma,  Ji C. Bihl,  Yi Yang, 
  • First Published: 28 May 2017
Review Article
Open Access

Mitophagy Transcriptome: Mechanistic Insights into Polyphenol-Mediated Mitophagy

Sijie Tan,  Esther Wong, 
  • First Published: 25 May 2017
Research Article
Open Access

The Effects of Blast Exposure on Protein Deimination in the Brain

Peter J. Attilio,  Michael Flora,  Alaa Kamnaksh,  Donald J. Bradshaw,  Denes Agoston,  Gregory P. Mueller, 
  • First Published: 24 May 2017
Review Article
Open Access

NADPH Oxidases: Insights into Selected Functions and Mechanisms of Action in Cancer and Stem Cells

Magdalena Skonieczna,  Tomasz Hejmo,  Aleksandra Poterala-Hejmo,  Artur Cieslar-Pobuda,  Rafal J. Buldak, 
  • First Published: 23 May 2017
Research Article
Open Access

Tubulin Beta-3 Chain as a New Candidate Protein Biomarker of Human Skin Aging: A Preliminary Study

Sylvia G. Lehmann,  Sandrine Bourgoin-Voillard,  Michel Seve,  Walid Rachidi, 
  • First Published: 23 May 2017
Research Article
Open Access

Hepatoprotective Effect of Polyphenol-Enriched Fraction from Folium Microcos on Oxidative Stress and Apoptosis in Acetaminophen-Induced Liver Injury in Mice

Hongtan Wu,  Gang Zhang,  Lisen Huang,  Haiyue Pang,  Na Zhang,  Yupei Chen,  Gueyhorng Wang, 
  • First Published: 23 May 2017
Review Article
Open Access

The Impact of Environmental Factors in Influencing Epigenetics Related to Oxidative States in the Cardiovascular System

Francesco Angelini,  Francesca Pagano,  Antonella Bordin,  Marika Milan,  Isotta Chimenti,  Mariangela Peruzzi,  Valentina Valenti,  Antonino Marullo,  Leonardo Schirone,  Silvia Palmerio,  Sebastiano Sciarretta,  Colin E. Murdoch,  Giacomo Frati,  Elena De Falco, 
  • First Published: 21 May 2017
Research Article
Open Access

Enhancement of Mitochondrial Transfer by Antioxidants in Human Mesenchymal Stem Cells

Chia-Jung Li,  Po-Kong Chen,  Li-Yi Sun,  Cheng-Yoong Pang, 
  • First Published: 17 May 2017
Review Article
Open Access

Tissue- and Condition-Specific Isoforms of Mammalian Cytochrome c Oxidase Subunits: From Function to Human Disease

Christopher A. Sinkler,  Hasini Kalpage,  Joseph Shay,  Icksoo Lee,  Moh H. Malek,  Lawrence I. Grossman,  Maik Hüttemann, 
  • First Published: 16 May 2017
Research Article
Open Access

Ziziphus nummularia Inhibits Inflammation-Induced Atherogenic Phenotype of Human Aortic Smooth Muscle Cells

Manal Fardoun,  Tuqa Al-Shehabi,  Ahmed El-Yazbi,  Khodr Issa,  Fouad Zouein,  Dina Maaliki,  Rabah Iratni,  Ali H. Eid, 
  • First Published: 16 May 2017
Review Article
Open Access

Mechanisms Underlying the Essential Role of Mitochondrial Membrane Lipids in Yeast Chronological Aging

Younes Medkour,  Paméla Dakik,  Mélissa McAuley,  Karamat Mohammad,  Darya Mitrofanova,  Vladimir I. Titorenko, 
  • First Published: 16 May 2017
Review Article
Open Access

Cardiovascular Mitochondrial Dysfunction Induced by Cocaine: Biomarkers and Possible Beneficial Effects of Modulators of Oxidative Stress

Manuela Graziani,  Paolo Sarti,  Marzia Arese,  Maria Chiara Magnifico,  Aldo Badiani,  Luciano Saso, 
  • First Published: 16 May 2017
Review Article
Open Access

MicroRNA Regulation of Oxidative Stress-Induced Cellular Senescence

Huaije Bu,  Sophia Wedel,  Maria Cavinato,  Pidder Jansen-Dürr, 
  • First Published: 16 May 2017
Research Article
Open Access

Camellia sinensis Prevents Perinatal Nicotine-Induced Neurobehavioral Alterations, Tissue Injury, and Oxidative Stress in Male and Female Mice Newborns

Jamaan S. Ajarem,  Gadh Al-Basher,  Ahmed A. Allam,  Ayman M. Mahmoud, 
  • First Published: 15 May 2017
Research Article
Open Access

Antifatigue Effect of Luteolin-6-C-Neohesperidoside on Oxidative Stress Injury Induced by Forced Swimming of Rats through Modulation of Nrf2/ARE Signaling Pathways

Fang-fang Duan,  Ying Guo,  Jing-wan Li,  Ke Yuan, 
  • First Published: 15 May 2017
Research Article
Open Access

The Stimulated Glycolytic Pathway Is Able to Maintain ATP Levels and Kinetic Patterns of Bovine Epididymal Sperm Subjected to Mitochondrial Uncoupling

João D. A. Losano,  Juan Fernando Padín,  Iago Méndez-López,  Daniel S. R. Angrimani,  Antonio G. García,  Valquiria H. Barnabe,  Marcilio Nichi, 
  • First Published: 09 May 2017
Research Article
Open Access

Antioxidant Treatment Induces Hyperactivation of the HPA Axis by Upregulating ACTH Receptor in the Adrenal and Downregulating Glucocorticoid Receptors in the Pituitary

Jessika P. Prevatto,  Rafael C. Torres,  Bruno L. Diaz,  Patrícia M. R. e Silva,  Marco A. Martins,  Vinicius F. Carvalho, 
  • First Published: 09 May 2017
Review Article
Open Access

Hypoxia in Obesity and Diabetes: Potential Therapeutic Effects of Hyperoxia and Nitrate

Reza Norouzirad,  Pedro González-Muniesa,  Asghar Ghasemi, 
  • First Published: 08 May 2017
Review Article
Open Access

Small Dense Low-Density Lipoprotein as Biomarker for Atherosclerotic Diseases

Ekaterina A. Ivanova,  Veronika A. Myasoedova,  Alexandra A. Melnichenko,  Andrey V. Grechko,  Alexander N. Orekhov, 
  • First Published: 07 May 2017
Research Article
Open Access

Spontaneous Production of Glutathione-Conjugated Forms of 1,2-Dichloropropane: Comparative Study on Metabolic Activation Processes of Dihaloalkanes Associated with Occupational Cholangiocarcinoma

Yu Toyoda,  Tappei Takada,  Hiroshi Suzuki, 
  • First Published: 07 May 2017
Research Article
Open Access

Pterostilbene 4′-β-Glucoside Protects against DSS-Induced Colitis via Induction of Tristetraprolin

Yingqing Chen,  Jeongmin Park,  Yeonsoo Joe,  Hyeok-Jun Park,  Seung-Joo Jekal,  Daisuke Sato,  Hiroki Hamada,  Hun Taeg Chung, 
  • First Published: 07 May 2017
Research Article
Open Access

Red Yeast Rice Protects Circulating Bone Marrow-Derived Proangiogenic Cells against High-Glucose-Induced Senescence and Oxidative Stress: The Role of Heme Oxygenase-1

Jung-Tung Liu,  Huey-Yi Chen,  Wen-Chi Chen,  Kee-Ming Man,  Yung-Hsiang Chen, 
  • First Published: 07 May 2017
Research Article
Open Access

Mitochondrial Transfer from Wharton’s Jelly Mesenchymal Stem Cell to MERRF Cybrid Reduces Oxidative Stress and Improves Mitochondrial Bioenergetics

Yao-Chung Chuang,  Chia-Wei Liou,  Shang-Der Chen,  Pei-Wen Wang,  Jiin-Haur Chuang,  Mao-Meng Tiao,  Te-Yao Hsu,  Hung-Yu Lin,  Tsu-Kung Lin, 
  • First Published: 04 May 2017
Review Article
Open Access

Sirt1 Inhibits Oxidative Stress in Vascular Endothelial Cells

Weijin Zhang,  Qiaobing Huang,  Zhenhua Zeng,  Jie Wu,  Yaoyuan Zhang,  Zhongqing Chen, 
  • First Published: 04 May 2017
Review Article
Open Access

Caveolin-1: An Oxidative Stress-Related Target for Cancer Prevention

Shengqi Wang,  Neng Wang,  Yifeng Zheng,  Jin Zhang,  Fengxue Zhang,  Zhiyu Wang, 
  • First Published: 04 May 2017
Review Article
Open Access

Monoamine Oxidases, Oxidative Stress, and Altered Mitochondrial Dynamics in Cardiac Ageing

Damien Maggiorani,  Nicola Manzella,  Dale E. Edmondson,  Andrea Mattevi,  Angelo Parini,  Claudia Binda,  Jeanne Mialet-Perez, 
  • First Published: 04 May 2017
Research Article
Open Access

The Repeated Administration of Resveratrol Has Measurable Effects on Circulating T-Cell Subsets in Humans

J. Luis Espinoza,  Ly Quoc Trung,  Pleiades T. Inaoka,  Kayoko Yamada,  Dao T. An,  Shohei Mizuno,  Shinji Nakao,  Akiyoshi Takami, 
  • First Published: 04 May 2017
Research Article
Open Access

Cytoprotective Mechanisms Mediated by Polyphenols from Chilean Native Berries against Free Radical-Induced Damage on AGS Cells

Felipe Ávila,  Cristina Theoduloz,  Camilo López-Alarcón,  Eva Dorta,  Guillermo Schmeda-Hirschmann, 
  • First Published: 02 May 2017
Research Article
Open Access

Protective Effects of Methane-Rich Saline on Rats with Lipopolysaccharide-Induced Acute Lung Injury

Aijun Sun,  Weiheng Wang,  Xiaojian Ye,  Yang Wang,  Xiangqun Yang,  Zhouheng Ye,  Xuejun Sun,  Chuansen Zhang, 
  • First Published: 02 May 2017
Research Article
Open Access

Therapeutic Hypothermia Reduces Oxidative Damage and Alters Antioxidant Defenses after Cardiac Arrest

Fernanda S. Hackenhaar,  Tássia M. Medeiros,  Fernanda M. Heemann,  Camile S. Behling,  Jordana S. Putti,  Camila D. Mahl,  Cleber Verona,  Ana Carolina A. da Silva,  Maria C. Guerra,  Carlos A. S. Gonçalves,  Vanessa M. Oliveira,  Diego F. M. Riveiro,  Silvia R. R. Vieira,  Mara S. Benfato, 
  • First Published: 02 May 2017
Research Article
Open Access

Application of Numerical Analysis of the Shape of Electron Paramagnetic Resonance Spectra for Determination of the Number of Different Groups of Radicals in the Burn Wounds

Paweł Olczyk,  Katarzyna Komosinska-Vassev,  Paweł Ramos,  Łukasz Mencner,  Krystyna Olczyk,  Barbara Pilawa, 
  • First Published: 02 May 2017
Research Article
Open Access

HIV-1 Transactivator Protein Induces ZO-1 and Neprilysin Dysfunction in Brain Endothelial Cells via the Ras Signaling Pathway

Wenlin Jiang,  Wen Huang,  Yanlan Chen,  Min Zou,  Dingyue Peng,  Debing Chen, 
  • First Published: 02 May 2017
Editorial
Open Access

Oxidative Stress and Inflammation in Cardiovascular Disease

Noemí García,  Cecilia Zazueta,  Leopoldo Aguilera-Aguirre, 
  • First Published: 27 April 2017
Editorial
Open Access

Dietary Supplements/Antioxidants: Impact on Redox Status in Brain Diseases

Gilles J. Guillemin,  Musthafa Mohamed Essa,  Byoung-Joon Song,  Thamilarasan Manivasagam, 
  • First Published: 26 April 2017
Editorial
Open Access

Oxidative Stress in Liver Diseases: Pathogenesis, Prevention, and Therapeutics

Ravirajsinh N. Jadeja,  Ranjitsinh V. Devkar,  Srinivas Nammi, 
  • First Published: 26 April 2017
Research Article
Open Access

H2S Donor NaHS Changes the Production of Endogenous H2S and NO in D-Galactose-Induced Accelerated Ageing

Wei Wu,  Cui-Lan Hou,  Xue-Pan Mu,  Chen Sun,  Yi-Chun Zhu,  Ming-Jie Wang,  Qian-Zhou Lv, 
  • First Published: 23 April 2017
Corrigendum
Open Access

Corrigendum to “Basic Fibroblast Growth Factor Inhibits Apoptosis and Promotes Proliferation of Adipose-Derived Mesenchymal Stromal Cells Isolated from Patients with Type 2 Diabetes by Reducing Cellular Oxidative Stress”

Daria Nawrocka,  Katarzyna Kornicka,  Joanna Szydlarska,  Krzysztof Marycz, 
  • First Published: 22 April 2017

Corrigendum
Open Access

Corrigendum to “(−)-Epicatechin Prevents Blood Pressure Increase and Reduces Locomotor Hyperactivity in Young Spontaneously Hypertensive Rats”

M. Kluknavsky,  P. Balis,  A. Puzserova,  J. Radosinska,  A. Berenyiova,  M. Drobna,  S. Lukac,  J. Muchova,  I. Bernatova, 
  • First Published: 20 April 2017

Review Article
Open Access

Research Progress on Signaling Pathway-Associated Oxidative Stress in Endothelial Cells

Ying Liang,  Jiajia Li,  Qinlu Lin,  Ping Huang,  Lin Zhang,  Wei Wu,  Youchu Ma, 
  • First Published: 19 April 2017
Review Article
Open Access

Potential of Lichen Compounds as Antidiabetic Agents with Antioxidative Properties: A Review

Vinitha M. Thadhani,  Veranja Karunaratne, 
  • First Published: 12 April 2017
Research Article
Open Access

Inhibition of miR-302 Suppresses Hypoxia-Reoxygenation-Induced H9c2 Cardiomyocyte Death by Regulating Mcl-1 Expression

Yao-Ching Fang,  Chi-Hsiao Yeh, 
  • First Published: 11 April 2017
Review Article
Open Access

Opuntia spp.: Characterization and Benefits in Chronic Diseases

María del Socorro Santos Díaz,  Ana-Paulina Barba de la Rosa,  Cécile Héliès-Toussaint,  Françoise Guéraud,  Anne Nègre-Salvayre, 
  • First Published: 09 April 2017
Research Article
Open Access

4-Hydroxynonenal Contributes to Angiogenesis through a Redox-Dependent Sphingolipid Pathway: Prevention by Hydralazine Derivatives

Caroline Camaré,  Corinne Vanucci-Bacqué,  Nathalie Augé,  Mélanie Pucelle,  Corinne Bernis,  Audrey Swiader,  Michel Baltas,  Florence Bedos-Belval,  Robert Salvayre,  Anne Nègre-Salvayre, 
  • First Published: 05 April 2017
Research Article
Open Access

A Single Zidovudine (AZT) Administration Delays Hepatic Cell Proliferation by Altering Oxidative State in the Regenerating Rat Liver

Armando Butanda-Ochoa,  Diego Rolando Hernández-Espinosa,  Marisela Olguín-Martínez,  Lourdes Sánchez-Sevilla,  Mario R. Rodríguez,  Benito Chávez-Rentería,  Alberto Aranda-Fraustro,  Rolando Hernández-Muñoz, 
  • First Published: 05 April 2017
Research Article
Open Access

HO-1 Is Essential for Tetrahydroxystilbene Glucoside Mediated Mitochondrial Biogenesis and Anti-Inflammation Process in LPS-Treated RAW264.7 Macrophages

Weihua Yu,  Xiaodi Zhang,  Hao Wu,  Qingbiao Zhou,  Zhao Wang,  Rui Liu,  Jiangzheng Liu,  Xin Wang,  Chunxu Hai, 
  • First Published: 03 April 2017
Review Article
Open Access

Involvement of Nrf2 in Ocular Diseases

Shehzad Batliwala,  Christy Xavier,  Yang Liu,  Hongli Wu,  Iok-Hou Pang, 
  • First Published: 03 April 2017
Research Article
Open Access

Dihydropyridine Derivatives as Cell Growth Modulators In Vitro

Imanta Bruvere,  Egils Bisenieks,  Janis Poikans,  Janis Uldrikis,  Aiva Plotniece,  Karlis Pajuste,  Martins Rucins,  Brigita Vigante,  Zenta Kalme,  Marina Gosteva,  Ilona Domracheva,  Astrida Velena,  Tea Vukovic,  Lidija Milkovic,  Gunars Duburs,  Neven Zarkovic, 
  • First Published: 03 April 2017
Research Article
Open Access

Paricalcitol Pretreatment Attenuates Renal Ischemia-Reperfusion Injury via Prostaglandin E2 Receptor EP4 Pathway

Yu Ah Hong,  Keum Jin Yang,  So Young Jung,  Ki Cheol Park,  Hyunsu Choi,  Jeong Min Oh,  Sang Ju Lee,  Yoon Kyung Chang,  Cheol Whee Park,  Chul Woo Yang,  Suk Young Kim,  Hyeon Seok Hwang, 
  • First Published: 29 March 2017

Research Article
Open Access

Role of Protein Kinase C and Nox2-Derived Reactive Oxygen Species Formation in the Activation and Maturation of Dendritic Cells by Phorbol Ester and Lipopolysaccharide

Judith Stein,  Sebastian Steven,  Matthias Bros,  Stephan Sudowe,  Michael Hausding,  Matthias Oelze,  Thomas Münzel,  Stephan Grabbe,  Angelika Reske-Kunz,  Andreas Daiber, 
  • First Published: 28 March 2017
Research Article
Open Access

Evaluating the Risk of Tumors Diseases Based on Measurement of Urinary and Serumal Antioxidants Using the New Agar Diffusion Methods

Ying Zhou,  Jing Chen,  Zhen Wang,  Hui Liu, 
  • First Published: 28 March 2017
Research Article
Open Access

Distinguishing the Unique Neuropathological Profile of Blast Polytrauma

W. Brad Hubbard,  Shaylen Greenberg,  Carly Norris,  Joseph Eck,  Erin Lavik,  Pamela VandeVord, 
  • First Published: 23 March 2017
Research Article
Open Access

A Clinically Relevant Variant of the Human Hydrogen Sulfide-Synthesizing Enzyme Cystathionine β-Synthase: Increased CO Reactivity as a Novel Molecular Mechanism of Pathogenicity?

João B. Vicente,  Henrique G. Colaço,  Francesca Malagrinò,  Paulo E. Santo,  André Gutierres,  Tiago M. Bandeiras,  Paula Leandro,  José A. Brito,  Alessandro Giuffrè, 
  • First Published: 22 March 2017
Research Article
Open Access

Antiretroviral Therapy Initiation Alters the Redox System of Asymptomatic HIV-Infected Individuals: A Longitudinal Study

Karen Ingrid Tasca,  Juliana Trindade Caleffi,  Camila Renata Correa,  Mariana Gatto,  Francilene Capel Tavares,  Caio Cavassan Camargo,  Alexandrina Sartori,  Mara Biasin,  Lenice do Rosário de Souza, 
  • First Published: 21 March 2017
Research Article
Open Access

Protective Effects of Dinitrosyl Iron Complexes under Oxidative Stress in the Heart

Valery I. Kapelko,  Vladimir L. Lakomkin,  Alexander A. Abramov,  Elena V. Lukoshkova,  Nidas A. Undrovinas,  Asker Y. Khapchaev,  Vladimir P. Shirinsky, 
  • First Published: 21 March 2017
Research Article
Open Access

Differential Regulation of Cardiac Function and Intracardiac Cytokines by Rapamycin in Healthy and Diabetic Rats

Christian Luck,  Vincent G. DeMarco,  Abuzar Mahmood,  Madhavi P. Gavini,  Lakshmi Pulakat, 
  • First Published: 20 March 2017
Research Article
Open Access

Effect of Red Orange Juice Consumption on Body Composition and Nutritional Status in Overweight/Obese Female: A Pilot Study

E. Azzini,  E. Venneria,  D. Ciarapica,  M. S. Foddai,  F. Intorre,  M. Zaccaria,  F. Maiani,  L. Palomba,  L. Barnaba,  C. Tubili,  G. Maiani,  A. Polito, 
  • First Published: 20 March 2017
Research Article
Open Access

Long-Term Effects of Maternal Deprivation on Redox Regulation in Rat Brain: Involvement of NADPH Oxidase

Branka Marković,  Nevena V. Radonjić,  Gordana Jevtić,  Tihomir Stojković,  Milica Velimirović,  Milan Aksić,  Joko Poleksić,  Tatjana Nikolić,  Dubravka Aleksić,  Vidosava Radonjić,  Branislav Filipović,  Nataša D. Petronijević, 
  • First Published: 20 March 2017
Review Article
Open Access

Physical Exercise on Inflammatory Markers in Type 2 Diabetes Patients: A Systematic Review of Randomized Controlled Trials

Luciana Costa Melo,  Jaime Dativo-Medeiros,  Carlos Eduardo Menezes-Silva,  Fabiano Timbó Barbosa,  Célio Fernando de Sousa-Rodrigues,  Luiza A. Rabelo, 
  • First Published: 19 March 2017
Research Article
Open Access

Impact on Autophagy and Ultraviolet B Induced Responses of Treatment with the MTOR Inhibitors Rapamycin, Everolimus, Torin 1, and pp242 in Human Keratinocytes

Song Xu,  Li Li,  Min Li,  Mengli Zhang,  Mei Ju,  Xu Chen,  Heng Gu, 
  • First Published: 16 March 2017
Corrigendum
Open Access

Corrigendum to “The Overexpression of NALP3 Inflammasome in Knee Osteoarthritis Is Associated with Synovial Membrane Prolidase and NADPH Oxidase 2”

Denise Clavijo-Cornejo,  Karina Martínez-Flores,  Karina Silva-Luna,  Gabriela Angélica Martínez-Nava,  Javier Fernández-Torres,  Yessica Zamudio-Cuevas,  Mónica Guadalupe Santamaría-Olmedo,  Julio Granados-Montiel,  Carlos Pineda,  Alberto López-Reyes, 
  • First Published: 16 March 2017

Research Article
Open Access

[Retracted] Molecular Hydrogen Effectively Heals Alkali-Injured Cornea via Suppression of Oxidative Stress

Cestmir Cejka,  Jan Kossl,  Barbora Hermankova,  Vladimir Holan,  Jitka Cejkova, 
  • First Published: 16 March 2017

Research Article
Open Access

Characterization of NO-Induced Nitrosative Status in Human Placenta from Pregnant Women with Gestational Diabetes Mellitus

Francisco Visiedo,  Celeste Santos-Rosendo,  Rosa M. Mateos-Bernal,  M. del Mar Gil-Sánchez,  Fernando Bugatto,  Manuel Aguilar-Diosdado,  Carmen Segundo,  Cristina López-Tinoco, 
  • First Published: 16 March 2017
Research Article
Open Access

Cinnamon Polyphenol Extract Inhibits Hyperlipidemia and Inflammation by Modulation of Transcription Factors in High-Fat Diet-Fed Rats

Zeynep Tuzcu,  Cemal Orhan,  Nurhan Sahin,  Vijaya Juturu,  Kazim Sahin, 
  • First Published: 15 March 2017
Editorial
Open Access

Oxidative Stress in Retinal Diseases

Yuhei Nishimura,  Hideaki Hara,  Mineo Kondo,  Samin Hong,  Takeshi Matsugi, 
  • First Published: 15 March 2017
Research Article
Open Access

The Transcription Factor Bach1 Suppresses the Developmental Angiogenesis of Zebrafish

Li Jiang,  Meng Yin,  Jie Xu,  Mengping Jia,  Shaoyang Sun,  Xu Wang,  Jianyi Zhang,  Dan Meng, 
  • First Published: 14 March 2017

Review Article
Open Access

ROS: Crucial Intermediators in the Pathogenesis of Intervertebral Disc Degeneration

Chencheng Feng,  Minghui Yang,  Minghong Lan,  Chang Liu,  Yang Zhang,  Bo Huang,  Huan Liu,  Yue Zhou, 
  • First Published: 14 March 2017
Research Article
Open Access

Amifostine Pretreatment Attenuates Myocardial Ischemia/Reperfusion Injury by Inhibiting Apoptosis and Oxidative Stress

Shao-ze Wu,  Lu-yuan Tao,  Jiao-ni Wang,  Zhi-qiang Xu,  Jie Wang,  Yang-jing Xue,  Kai-yu Huang,  Jia-feng Lin,  Lei Li,  Kang-ting Ji, 
  • First Published: 14 March 2017
Research Article
Open Access

Cerium Oxide Nanoparticles in Lung Acutely Induce Oxidative Stress, Inflammation, and DNA Damage in Various Organs of Mice

Abderrahim Nemmar,  Priya Yuvaraju,  Sumaya Beegam,  Mohamed A. Fahim,  Badreldin H. Ali, 
  • First Published: 14 March 2017
Research Article
Open Access

A Fermented Whole Grain Prevents Lipopolysaccharides-Induced Dysfunction in Human Endothelial Progenitor Cells

Laura Giusti,  Morena Gabriele,  Giuseppe Penno,  Monia Garofolo,  Vincenzo Longo,  Stefano Del Prato,  Daniela Lucchesi,  Laura Pucci, 
  • First Published: 13 March 2017
Review Article
Open Access

A Preclinical Systematic Review of Ginsenoside-Rg1 in Experimental Parkinson’s Disease

Liang Song,  Meng-Bei Xu,  Xiao-Li Zhou,  Dao-pei Zhang,  Shu-ling Zhang,  Guo-qing Zheng, 
  • First Published: 13 March 2017

Research Article
Open Access

Antioxidant and Ex Vivo Immune System Regulatory Properties of Boswellia serrata Extracts

Daniela Beghelli,  Gloria Isani,  Paola Roncada,  Giulia Andreani,  Onelia Bistoni,  Martina Bertocchi,  Giulio Lupidi,  Alessia Alunno, 
  • First Published: 13 March 2017
Review Article
Open Access

The Utility of Ovotransferrin and Ovotransferrin-Derived Peptides as Possible Candidates in the Clinical Treatment of Cardiovascular Diseases

Shuang Chen,  Hongmei Jiang,  Hanhui Peng,  Xiaosong Wu,  Jun Fang, 
  • First Published: 13 March 2017

Review Article
Open Access

Recent Advances and Challenges of mTOR Inhibitors Use in the Treatment of Patients with Tuberous Sclerosis Complex

Filipe Palavra,  Conceição Robalo,  Flávio Reis, 
  • First Published: 12 March 2017
Research Article
Open Access

Kiwifruit Alleviates Learning and Memory Deficits Induced by Pb through Antioxidation and Inhibition of Microglia Activation In Vitro and In Vivo

Wei-Zhen Xue,  Qian-Qian Yang,  Yiwen Chen,  Rong-Xin Zou,  Dong Xing,  Yi Xu,  Yong-Sheng Liu,  Hui-Li Wang, 
  • First Published: 12 March 2017
Research Article
Open Access

Alleviation of Oxidative Damage and Involvement of Nrf2-ARE Pathway in Mesodopaminergic System and Hippocampus of Status Epilepticus Rats Pretreated by Intranasal Pentoxifylline

Yunxiao Kang,  Wensheng Yan,  Hui Fang,  Guoliang Zhang,  Yakun Du,  Lei Wang,  Huixian Cui,  Geming Shi, 
  • First Published: 12 March 2017
Research Article
Open Access

The Citrus Flavanone Naringenin Protects Myocardial Cells against Age-Associated Damage

Eleonora Da Pozzo,  Barbara Costa,  Chiara Cavallini,  Lara Testai,  Alma Martelli,  Vincenzo Calderone,  Claudia Martini, 
  • First Published: 12 March 2017
Research Article
Open Access

Dietary Saccharomyces cerevisiae Cell Wall Extract Supplementation Alleviates Oxidative Stress and Modulates Serum Amino Acids Profiles in Weaned Piglets

Gang Liu,  Lei Yu,  Yordan Martínez,  Wenkai Ren,  Hengjia Ni,  Naif Abdullah Al-Dhabi,  Veeramuthu Duraipandiyan,  Yulong Yin, 
  • First Published: 12 March 2017
Research Article
Open Access

Sulforaphane Protects against High Cholesterol-Induced Mitochondrial Bioenergetics Impairments, Inflammation, and Oxidative Stress and Preserves Pancreatic β-Cells Function

Catalina Carrasco-Pozo,  Kah Ni Tan,  Martin Gotteland,  Karin Borges, 
  • First Published: 12 March 2017
Research Article
Open Access

Antioxidant, Cytotoxic, and Toxic Activities of Propolis from Two Native Bees in Brazil: Scaptotrigona depilis and Melipona quadrifasciata anthidioides

Thaliny Bonamigo,  Jaqueline Ferreira Campos,  Tamaeh Monteiro Alfredo,  José Benedito Perrella Balestieri,  Claudia Andrea Lima Cardoso,  Edgar Julian Paredes-Gamero,  Kely de Picoli Souza,  Edson Lucas dos Santos, 
  • First Published: 09 March 2017
Review Article
Open Access

Crosstalk between Tryptophan Metabolism and Cardiovascular Disease, Mechanisms, and Therapeutic Implications

Gang Liu,  Shuai Chen,  Jin Zhong,  Kunling Teng,  Yulong Yin, 
  • First Published: 09 March 2017
Research Article
Open Access

Redox Regulating Enzymes and Connected MicroRNA Regulators Have Prognostic Value in Classical Hodgkin Lymphomas

Peeter Karihtala,  Katja Porvari,  Ylermi Soini,  Kirsi-Maria Haapasaari, 
  • First Published: 09 March 2017
Research Article
Open Access

Acarbose Accelerates Wound Healing via Akt/eNOS Signaling in db/db Mice

Xue Han,  Yaping Deng,  Jiawen Yu,  Yuannan Sun,  Guofei Ren,  Jian Cai,  Jianjun Zhu,  Guojun Jiang, 
  • First Published: 08 March 2017
Research Article
Open Access

Reperfusion Therapy with Rapamycin Attenuates Myocardial Infarction through Activation of AKT and ERK

Scott M. Filippone,  Arun Samidurai,  Sean K. Roh,  Chad K. Cain,  Jun He,  Fadi N. Salloum,  Rakesh C. Kukreja,  Anindita Das, 
  • First Published: 08 March 2017
Research Article
Open Access

Prevention of Streptozotocin-Induced Diabetic Nephropathy by MG132: Possible Roles of Nrf2 and IκB

Lili Kong,  Yangwei Wang,  Manyu Luo,  Yi Tan,  Wenpeng Cui,  Lining Miao, 
  • First Published: 08 March 2017
Research Article
Open Access

Capsular Polysaccharide of Mycoplasma ovipneumoniae Induces Sheep Airway Epithelial Cell Apoptosis via ROS-Dependent JNK/P38 MAPK Pathways

Zhongjia Jiang,  Fuyang Song,  Yanan Li,  Di Xue,  Ning Zhao,  Jiamei Zhang,  Guangcun Deng,  Min Li,  Xiaoming Liu,  Yujiong Wang, 
  • First Published: 07 March 2017
Research Article
Open Access

Development and In Vitro Evaluation of an Innovative “Dietary Flavonoid Supplement” on Osteoarthritis Process

Maria Rosaria Lauro,  Lucia Crascí,  Francesca Sansone,  Venera Cardile,  Anna Maria Panico,  Giovanni Puglisi, 
  • First Published: 07 March 2017
Research Article
Open Access

Spermidine Oxidation-Mediated Degeneration of Retinal Pigment Epithelium in Rats

Koji Ohashi,  Masaaki Kageyama,  Katsuhiko Shinomiya,  Yukie Fujita-Koyama,  Shin-ichiro Hirai,  Osamu Katsuta,  Masatsugu Nakamura, 
  • First Published: 07 March 2017
Research Article
Open Access

Nicotinamide Adenine Dinucleotide Protects against Spinal Cord Ischemia Reperfusion Injury-Induced Apoptosis by Blocking Autophagy

Lei Xie,  Sifei Yu,  Zhenfei Wang,  Kai Yang,  Zhuochao Liu,  Changwei Li,  Yu Liang, 
  • First Published: 07 March 2017
Research Article
Open Access

Protection of Human Umbilical Vein Endothelial Cells against Oxidative Stress by MicroRNA-210

Tianyi Li,  Xianjing Song,  Jichang Zhang,  Lei Zhao,  Yongfeng Shi,  Zhibo Li,  Jia Liu,  Ning Liu,  Youyou Yan,  Yanlong Xiao,  Xin Tian,  Wei Sun,  Yinuo Guan,  Bin Liu, 
  • First Published: 07 March 2017
Research Article
Open Access

Reactive Oxygen Species Evoked by Potassium Deprivation and Staurosporine Inactivate Akt and Induce the Expression of TXNIP in Cerebellar Granule Neurons

Marco Antonio Zaragoza-Campillo,  Julio Morán, 
  • First Published: 06 March 2017
Research Article
Open Access

The Hepatoprotective and MicroRNAs Downregulatory Effects of Crocin Following Hepatic Ischemia-Reperfusion Injury in Rats

Ghaidafeh Akbari,  Seyyed Ali Mard,  Mahin Dianat,  Esrafil Mansouri, 
  • First Published: 06 March 2017
Review Article
Open Access

Eag1 K+ Channel: Endogenous Regulation and Functions in Nervous System

Bo Han,  Tursonjan Tokay,  Guangming Zhang,  Peng Sun,  Shangwei Hou, 
  • First Published: 06 March 2017
Research Article
Open Access

Obesity Downregulates MicroRNA-126 Inducing Capillary Rarefaction in Skeletal Muscle: Effects of Aerobic Exercise Training

João Lucas Penteado Gomes,  Tiago Fernandes,  Ursula Paula Reno Soci,  André Casanova Silveira,  Diego Lopes Mendes Barretti,  Carlos Eduardo Negrão,  Edilamar Menezes Oliveira, 
  • First Published: 06 March 2017
Review Article
Open Access

Exercise Modifies the Gut Microbiota with Positive Health Effects

Vincenzo Monda,  Ines Villano,  Antonietta Messina,  Anna Valenzano,  Teresa Esposito,  Fiorenzo Moscatelli,  Andrea Viggiano,  Giuseppe Cibelli,  Sergio Chieffi,  Marcellino Monda,  Giovanni Messina, 
  • First Published: 05 March 2017
Research Article
Open Access

Intramyocardial Injection of Recombinant Adeno-Associated Viral Vector Coexpressing PR39/Adrenomedullin Enhances Angiogenesis and Reduces Apoptosis in a Rat Myocardial Infarction Model

Rui An,  Cong Xi,  Jian Xu,  Ying Liu,  Shumiao Zhang,  Yuemin Wang,  Yuewen Hao,  Lijun Sun, 
  • First Published: 02 March 2017
Research Article
Open Access

BAG5 Interacts with DJ-1 and Inhibits the Neuroprotective Effects of DJ-1 to Combat Mitochondrial Oxidative Damage

Li-xia Qin,  Jie-qiong Tan,  Hai-nan Zhang,  Kousar Rizwana,  Jia-hong Lu,  Jian-guang Tang,  Bo Jiang,  Xiang-min Shen,  Ji-feng Guo,  Bei-sha Tang,  Li-ming Tan,  Chun-yu Wang, 
  • First Published: 02 March 2017
Review Article
Open Access

Multifarious Beneficial Effect of Nonessential Amino Acid, Glycine: A Review

Meerza Abdul Razak,  Pathan Shajahan Begum,  Buddolla Viswanath,  Senthilkumar Rajagopal, 
  • First Published: 01 March 2017

Editorial
Open Access

Lipid Peroxidation Products in Human Health and Disease 2016

Kota V. Ramana,  Sanjay Srivastava,  Sharad S. Singhal, 
  • First Published: 28 February 2017
Research Article
Open Access

Rat Liver Enzyme Release Depends on Blood Flow-Bearing Physical Forces Acting in Endothelium Glycocalyx rather than on Liver Damage

Julieta A. Díaz-Juárez,  Rolando Hernández-Muñoz, 
  • First Published: 28 February 2017
Research Article
Open Access

Pentaerythritol Tetranitrate In Vivo Treatment Improves Oxidative Stress and Vascular Dysfunction by Suppression of Endothelin-1 Signaling in Monocrotaline-Induced Pulmonary Hypertension

Sebastian Steven,  Matthias Oelze,  Moritz Brandt,  Elisabeth Ullmann,  Swenja Kröller-Schön,  Tjebo Heeren,  Lan P. Tran,  Steffen Daub,  Mobin Dib,  Dirk Stalleicken,  Philip Wenzel,  Thomas Münzel,  Andreas Daiber, 
  • First Published: 28 February 2017
Editorial
Open Access

Neuroprotection in Neurodegenerative Disease: From Basic Science to Clinical Applications

Marta C. Monteiro,  Michael D. Coleman,  Eric J. Hill,  Rui D. Prediger,  Cristiane S. F. Maia, 
  • First Published: 28 February 2017
Research Article
Open Access

Cellular Homeostasis and Antioxidant Response in Epithelial HT29 Cells on Titania Nanotube Arrays Surface

Rabiatul Basria SMN Mydin,  Srimala Sreekantan,  Roshasnorlyza Hazan,  Mustafa Fadzil Farid Wajidi,  Ishak Mat, 
  • First Published: 28 February 2017
Research Article
Open Access

Podocyte Injury and Albuminuria in Experimental Hyperuricemic Model Rats

Shinichiro Asakawa,  Shigeru Shibata,  Chikayuki Morimoto,  Takeshi Shiraishi,  Takashi Nakamura,  Yoshifuru Tamura,  Takanori Kumagai,  Makoto Hosoyamada,  Shunya Uchida, 
  • First Published: 28 February 2017
Editorial
Open Access

Oxidative Stress and Autophagy in Metabolism and Longevity

Ajit Vikram,  Ramakrishnan Anish,  Ashutosh Kumar,  Durga Nand Tripathi,  Ravinder K. Kaundal, 
  • First Published: 28 February 2017
Research Article
Open Access

Hepatoprotective Effects of Antrodia cinnamomea: The Modulation of Oxidative Stress Signaling in a Mouse Model of Alcohol-Induced Acute Liver Injury

Yange Liu,  Juan Wang,  Lanzhou Li,  Wenji Hu,  Yidi Qu,  Yipei Ding,  Lina Meng,  Lirong Teng,  Di Wang, 
  • First Published: 27 February 2017
Research Article
Open Access

Small Interfering RNA Targeting Mitochondrial Calcium Uniporter Improves Cardiomyocyte Cell Viability in Hypoxia/Reoxygenation Injury by Reducing Calcium Overload

Yuriana Oropeza-Almazán,  Eduardo Vázquez-Garza,  Héctor Chapoy-Villanueva,  Guillermo Torre-Amione,  Gerardo García-Rivas, 
  • First Published: 27 February 2017
Research Article
Open Access

Autophagy Is a Protective Response to the Oxidative Damage to Endplate Chondrocytes in Intervertebral Disc: Implications for the Treatment of Degenerative Lumbar Disc

Ke Chen,  Xiaohua Lv,  Wei Li,  Fei Yu,  Jianjing Lin,  Junxuan Ma,  Deming Xiao, 
  • First Published: 22 February 2017
Research Article
Open Access

Antigenotoxic Properties of Agaricus blazei against Hydrogen Peroxide in Human Peripheral Blood Cells

Lada Živković,  Sunčica Borozan,  Andrea Čabarkapa,  Dijana Topalović,  Ummi Ciptasari,  Vladan Bajić,  Biljana Spremo-Potparević, 
  • First Published: 21 February 2017
Review Article
Open Access

Carrageenan Based Bionanocomposites as Drug Delivery Tool with Special Emphasis on the Influence of Ferromagnetic Nanoparticles

Abida Kalsoom Khan,  Ain Us Saba,  Shamyla Nawazish,  Fahad Akhtar,  Rehana Rashid,  Sadullah Mir,  Bushra Nasir,  Furqan Iqbal,  Samina Afzal,  Fahad Pervaiz,  Ghulam Murtaza, 
  • First Published: 20 February 2017
Research Article
Open Access

Diallyl Trisulfide Suppresses Oxidative Stress-Induced Activation of Hepatic Stellate Cells through Production of Hydrogen Sulfide

Feng Zhang,  Huanhuan Jin,  Li Wu,  Jiangjuan Shao,  Xiaojing Zhu,  Anping Chen,  Shizhong Zheng, 
  • First Published: 20 February 2017
Research Article
Open Access

TBHQ Alleviated Endoplasmic Reticulum Stress-Apoptosis and Oxidative Stress by PERK-Nrf2 Crosstalk in Methamphetamine-Induced Chronic Pulmonary Toxicity

Yun Wang,  Yu-Han Gu,  Ming Liu,  Yang Bai,  Li-Ye Liang,  Huai-Liang Wang, 
  • First Published: 20 February 2017
Review Article
Open Access

Astragaloside IV for Experimental Focal Cerebral Ischemia: Preclinical Evidence and Possible Mechanisms

Hui-Lin Wang,  Qi-Hui Zhou,  Meng-Bei Xu,  Xiao-Li Zhou,  Guo-Qing Zheng, 
  • First Published: 20 February 2017
Research Article
Open Access

Cellular Preoxygenation Partially Attenuates the Antitumoral Effect of Cisplatin despite Highly Protective Effects on Renal Epithelial Cells

Bahram Rasoulian,  Ayat Kaeidi,  Maryam Rezaei,  Zahra Hajializadeh, 
  • First Published: 19 February 2017
Review Article
Open Access

Insights for Oxidative Stress and mTOR Signaling in Myocardial Ischemia/Reperfusion Injury under Diabetes

Dajun Zhao,  Jian Yang,  Lifang Yang, 
  • First Published: 19 February 2017
Research Article
Open Access

Influence of Synbiotics on Selected Oxidative Stress Parameters

Paulina Kleniewska,  Rafał Pawliczak, 
  • First Published: 13 February 2017
Review Article
Open Access

Aspects of Carbon Monoxide in Form of CO-Releasing Molecules Used in Cancer Treatment: More Light on the Way

Malamati Kourti,  Wen G. Jiang,  Jun Cai, 
  • First Published: 13 February 2017
Review Article
Open Access

A Review of mTOR Pathway Inhibitors in Gynecologic Cancer

Andréia Cristina de Melo,  Eduardo Paulino,  Álvaro Henrique Ingles Garces, 
  • First Published: 13 February 2017
Review Article
Open Access

Resistance to mTORC1 Inhibitors in Cancer Therapy: From Kinase Mutations to Intratumoral Heterogeneity of Kinase Activity

Seraina Faes,  Nicolas Demartines,  Olivier Dormond, 
  • First Published: 09 February 2017
Research Article
Open Access

The Short Isoform of DNAJB6 Protects against 1-Methyl-4-phenylpridinium Ion-Induced Apoptosis in LN18 Cells via Inhibiting Both ROS Formation and Mitochondrial Membrane Potential Loss

Yeon-Mi Hong,  Yohan Hong,  Yeong-Gon Choi,  Sujung Yeo,  Soo Hee Jin,  Sae-Won Lee,  Backil Sung,  Sook-Hyun Lee,  Hyejin Jung,  Sabina Lim, 
  • First Published: 09 February 2017
Research Article
Open Access

Reactive Oxygen Species Mediated Prostaglandin E2 Contributes to Acute Response of Epithelial Injury

Yi-Ping Hu,  Yin-Bo Peng,  Yi-Fan Zhang,  Ying Wang,  Wei-Rong Yu,  Min Yao,  Xiu-Jun Fu, 
  • First Published: 09 February 2017
Research Article
Open Access

Resveratrol Attenuates Copper-Induced Senescence by Improving Cellular Proteostasis

Liliana Matos,  Alexandra Monteiro Gouveia,  Henrique Almeida, 
  • First Published: 09 February 2017

Review Article
Open Access

Targeting Oxidative Stress for Treatment of Glaucoma and Optic Neuritis

Atsuko Kimura,  Kazuhiko Namekata,  Xiaoli Guo,  Takahiko Noro,  Chikako Harada,  Takayuki Harada, 
  • First Published: 08 February 2017
Research Article
Open Access

Triethylenetetramine Synergizes with Pharmacologic Ascorbic Acid in Hydrogen Peroxide Mediated Selective Toxicity to Breast Cancer Cell

Lianlian Wang,  Xiaofang Luo,  Cong Li,  Yubing Huang,  Ping Xu,  Laetitia H. Lloyd-Davies,  Thibaut Delplancke,  Chuan Peng,  Rufei Gao,  Hongbo Qi,  Chao Tong,  Philip Baker, 
  • First Published: 08 February 2017
Research Article
Open Access

The Neuroprotective Effects of Brazilian Green Propolis on Neurodegenerative Damage in Human Neuronal SH-SY5Y Cells

Junjun Ni,  Zhou Wu,  Jie Meng,  Aiqin Zhu,  Xin Zhong,  Shizheng Wu,  Hiroshi Nakanishi, 
  • First Published: 06 February 2017
Research Article
Open Access

Bioenergetic Changes during Differentiation of Human Embryonic Stem Cells along the Hepatic Lineage

Branden M. Hopkinson,  Claus Desler,  Mark Kalisz,  Peter Siig Vestentoft,  Lene Juel Rasmussen,  Hanne Cathrine Bisgaard, 
  • First Published: 06 February 2017
Review Article
Open Access

Oxidative Stress-Related Mechanisms and Antioxidant Therapy in Diabetic Retinopathy

Cheng Li,  Xiao Miao,  Fengsheng Li,  Shudong Wang,  Quan Liu,  Yonggang Wang,  Jian Sun, 
  • First Published: 06 February 2017
Research Article
Open Access

Parental High-Fat Diet Promotes Inflammatory and Senescence-Related Changes in Prostate

Kulbhushan Tikoo,  Ajit Vikram,  Shweta Shrivastava,  Gopabandhu Jena,  Heta Shah,  Richa Chhabra, 
  • First Published: 05 February 2017
Review Article
Open Access

Amino Acid Catabolism in Alzheimer’s Disease Brain: Friend or Foe?

Jeddidiah W. D. Griffin,  Patrick C. Bradshaw, 
  • First Published: 05 February 2017
Research Article
Open Access

Identification of Patients Affected by Mitral Valve Prolapse with Severe Regurgitation: A Multivariable Regression Model

Paola Songia,  Benedetta Porro,  Mattia Chiesa,  Veronika Myasoedova,  Francesco Alamanni,  Elena Tremoli,  Paolo Poggio, 
  • First Published: 02 February 2017

Editorial
Open Access

Oxidative Stress in Infection and Consequent Disease

Alexander V. Ivanov,  Birke Bartosch,  Maria G. Isaguliants, 
  • First Published: 01 February 2017
Editorial
Open Access

Oxidative Stress in the Newborn

Giuseppe Buonocore,  Serafina Perrone,  Maria Luisa Tataranno, 
  • First Published: 31 January 2017
Research Article
Open Access

Alcoholic Extract of Eclipta alba Shows In Vitro Antioxidant and Anticancer Activity without Exhibiting Toxicological Effects

Navneet Kumar Yadav,  Rakesh Kumar Arya,  Kapil Dev,  Chetan Sharma,  Zakir Hossain,  Sanjeev Meena,  K. R. Arya,  J. R. Gayen,  Dipak Datta,  R. K. Singh, 
  • First Published: 31 January 2017
Research Article
Open Access

African Ancestry Gradient Is Associated with Lower Systemic F2-Isoprostane Levels

Francis Annor,  Michael Goodman,  Bharat Thyagarajan,  Ike Okosun,  Ayo Doumatey,  Barbara A. Gower,  Dora Il’yasova, 
  • First Published: 31 January 2017
Editorial
Open Access

NRF2 as an Emerging Therapeutic Target

Ian M. Copple,  Albena T. Dinkova-Kostova,  Thomas W. Kensler,  Karen T. Liby,  W. Christian Wigley, 
  • First Published: 31 January 2017
Research Article
Open Access

Hydrogen Sulfide Prevents Formation of Reactive Oxygen Species through PI3K/Akt Signaling and Limits Ventilator-Induced Lung Injury

Sashko Georgiev Spassov,  Rosa Donus,  Paul Mikael Ihle,  Helen Engelstaedter,  Alexander Hoetzel,  Simone Faller, 
  • First Published: 31 January 2017

Editorial
Open Access

Oxidative Stress in Disease and Aging: Mechanisms and Therapies 2016

Claudio Cabello-Verrugio,  Felipe Simon,  Capucine Trollet,  Juan F. Santibañez, 
  • First Published: 26 January 2017
Research Article
Open Access

Decreased Tissue COX5B Expression and Mitochondrial Dysfunction during Sepsis-Induced Kidney Injury in Rats

Jochen Hinkelbein,  Lennert Böhm,  Stefan Braunecker,  Christoph Adler,  Edoardo De Robertis,  Fabrizio Cirillo, 
  • First Published: 26 January 2017
Research Article
Open Access

Gut Microbiota in a Rat Oral Sensitization Model: Effect of a Cocoa-Enriched Diet

Mariona Camps-Bossacoma,  Francisco J. Pérez-Cano,  Àngels Franch,  Margarida Castell, 
  • First Published: 25 January 2017
Research Article
Open Access

Evaluation of Anti-Inflammatory Properties of Isoorientin Isolated from Tubers of Pueraria tuberosa

Kotha Anilkumar,  Gorla V. Reddy,  Rajaram Azad,  Nagendra Sastry Yarla,  Gangappa Dharmapuri,  Anand Srivastava,  Mohammad A. Kamal,  Reddanna Pallu, 
  • First Published: 24 January 2017
Research Article
Open Access

Age and Environment Influences on Mouse Prion Disease Progression: Behavioral Changes and Morphometry and Stereology of Hippocampal Astrocytes

J. Bento-Torres,  L. L. Sobral,  R. R. Reis,  R. B. de Oliveira,  D. C. Anthony,  P. F. C. Vasconcelos,  Cristovam Wanderley Picanço Diniz, 
  • First Published: 24 January 2017
Research Article
Open Access

Immune Profile of Obese People and In Vitro Effects of Red Grape Polyphenols on Peripheral Blood Mononuclear Cells

Thea Magrone,  Emilio Jirillo,  Anna Spagnoletta,  Manrico Magrone,  Matteo Antonio Russo,  Sergio Fontana,  Flavia Laforgia,  Ilaria Donvito,  Angelo Campanella,  Franco Silvestris,  Giovanni De Pergola, 
  • First Published: 24 January 2017

Research Article
Open Access

Nutritional Supplementation Inhibits the Increase in Serum Malondialdehyde in Patients with Wet Age-Related Macular Degeneration

Toshiyuki Matsuura,  Kei Takayama,  Hiroki Kaneko,  Fuxiang Ye,  Hiroshi Fukukita,  Taichi Tsunekawa,  Keiko Kataoka,  Shiang-Jyi Hwang,  Yosuke Nagasaka,  Yasuki Ito,  Hiroko Terasaki, 
  • First Published: 24 January 2017
Research Article
Open Access

Aspalatone Prevents VEGF-Induced Lipid Peroxidation, Migration, Tube Formation, and Dysfunction of Human Aortic Endothelial Cells

Himangshu Sonowal,  Pabitra B. Pal,  Kirtikar Shukla,  Kota V. Ramana, 
  • First Published: 24 January 2017
Research Article
Open Access

Comparison of Effects of Different Statins on Contrast-Induced Acute Kidney Injury in Rats: Histopathological and Biochemical Findings

Xiao-lei Wang,  Tuo Zhang,  Liu-hua Hu,  Shi-qun Sun,  Wei-feng Zhang,  Zhe Sun,  Ling-hong Shen,  Ben He, 
  • First Published: 24 January 2017
Research Article
Open Access

A Chilean Berry Concentrate Protects against Postprandial Oxidative Stress and Increases Plasma Antioxidant Activity in Healthy Humans

Ines Urquiaga,  Felipe Ávila,  Guadalupe Echeverria,  Druso Perez,  Sebastian Trejo,  Federico Leighton, 
  • First Published: 24 January 2017
Research Article
Open Access

Tocotrienol-Rich Fraction Ameliorates Antioxidant Defense Mechanisms and Improves Replicative Senescence-Associated Oxidative Stress in Human Myoblasts

Shy Cian Khor,  Wan Zurinah Wan Ngah,  Yasmin Anum Mohd Yusof,  Norwahidah Abdul Karim,  Suzana Makpol, 
  • First Published: 24 January 2017
Research Article
Open Access

Plasma DNA Mediate Autonomic Dysfunctions and White Matter Injuries in Patients with Parkinson’s Disease

Meng-Hsiang Chen,  Pei-Chin Chen,  Cheng-Hsien Lu,  Hsiu-Ling Chen,  Yi-Ping Chao,  Shau-Hsuan Li,  Yi-Wen Chen,  Wei-Che Lin, 
  • First Published: 23 January 2017
Research Article
Open Access

Synthetic Isoliquiritigenin Inhibits Human Tongue Squamous Carcinoma Cells through Its Antioxidant Mechanism

Cuilan Hou,  Wenguang Li,  Zengyou Li,  Jing Gao,  Zhenjie Chen,  Xiqiong Zhao,  Yaya Yang,  Xiaoyu Zhang,  Yong Song, 
  • First Published: 22 January 2017
Editorial
Open Access

Interplay between Oxidative Stress and Metabolism in Signalling and Disease 2016

Eric E. Kelley,  Antonio Marcus de Andrade Paes,  Hariom Yadav,  Celia Quijano,  Adriana Cassina,  Andrés Trostchansky, 
  • First Published: 22 January 2017
Clinical Study
Open Access

Iron Supplementation Effects on Redox Status following Aseptic Skeletal Muscle Trauma in Adults and Children

Chariklia K. Deli,  Ioannis G. Fatouros,  Vassilis Paschalis,  Athanasios Tsiokanos,  Kalliopi Georgakouli,  Athanasios Zalavras,  Alexandra Avloniti,  Yiannis Koutedakis,  Athanasios Z. Jamurtas, 
  • First Published: 22 January 2017
Editorial
Open Access

Oxidative Stress and Inflammation in Hepatic Diseases: Current and Future Therapy

Karina Reyes-Gordillo,  Ruchi Shah,  Pablo Muriel, 
  • First Published: 22 January 2017
Research Article
Open Access

Hydrogen-Rich Water Ameliorates Total Body Irradiation-Induced Hematopoietic Stem Cell Injury by Reducing Hydroxyl Radical

Junling Zhang,  Xiaolei Xue,  Xiaodan Han,  Yuan Li,  Lu Lu,  Deguan Li,  Saijun Fan, 
  • First Published: 22 January 2017
Research Article
Open Access

Long-Term Treatment of Native LDL Induces Senescence of Cultured Human Endothelial Cells

Sung-Tack Oh,  Hoon Park,  Hyun Joong Yoon,  Sung Yeul Yang, 
  • First Published: 19 January 2017

Review Article
Open Access

Sirtuins Expression and Their Role in Retinal Diseases

Sankarathi Balaiya,  Khaled K. Abu-Amero,  Altaf A. Kondkar,  Kakarla V. Chalam, 
  • First Published: 19 January 2017
Review Article
Open Access

Relationships between Stress Granules, Oxidative Stress, and Neurodegenerative Diseases

Lihua Chen,  Beidong Liu, 
  • First Published: 18 January 2017
Review Article
Open Access

Retinal Diseases Associated with Oxidative Stress and the Effects of a Free Radical Scavenger (Edaravone)

Tomomi Masuda,  Masamitsu Shimazawa,  Hideaki Hara, 
  • First Published: 18 January 2017
Review Article
Open Access

Is p53 Involved in Tissue-Specific Insulin Resistance Formation?

Justyna Strycharz,  Jozef Drzewoski,  Janusz Szemraj,  Agnieszka Sliwinska, 
  • First Published: 17 January 2017

Research Article
Open Access

Mitochondrial Ferritin Deletion Exacerbates β-Amyloid-Induced Neurotoxicity in Mice

Peina Wang,  Qiong Wu,  Wenyue Wu,  Haiyan Li,  Yuetong Guo,  Peng Yu,  Guofen Gao,  Zhenhua Shi,  Baolu Zhao,  Yan-Zhong Chang, 
  • First Published: 16 January 2017
Research Article
Open Access

Oxidative Stress Triggered by Apigenin Induces Apoptosis in a Comprehensive Panel of Human Cervical Cancer-Derived Cell Lines

Raquel P. Souza,  Patrícia de S. Bonfim-Mendonça,  Fabrícia Gimenes,  Bianca A. Ratti,  Vanessa Kaplum,  Marcos L. Bruschi,  Celso V. Nakamura,  Sueli O. Silva,  Silvya S. Maria-Engler,  Marcia E. L. Consolaro, 
  • First Published: 16 January 2017
Research Article
Open Access

Impact of Yoga and Meditation on Cellular Aging in Apparently Healthy Individuals: A Prospective, Open-Label Single-Arm Exploratory Study

Madhuri Tolahunase,  Rajesh Sagar,  Rima Dada, 
  • First Published: 16 January 2017

Research Article
Open Access

Antibacterial, Anti-Inflammatory, Antioxidant, and Antiproliferative Properties of Essential Oils from Hairy and Normal Roots of Leonurus sibiricus L. and Their Chemical Composition

Przemysław Sitarek,  Patricia Rijo,  Catarina Garcia,  Ewa Skała,  Danuta Kalemba,  Adam J. Białas,  Janusz Szemraj,  Dariusz Pytel,  Monika Toma,  Halina Wysokińska,  Tomasz Śliwiński, 
  • First Published: 16 January 2017
Research Article
Open Access

Sulforaphane Prevents Angiotensin II-Induced Testicular Cell Death via Activation of NRF2

Yonggang Wang,  Hao Wu,  Ying Xin,  Yang Bai,  Lili Kong,  Yi Tan,  Feng Liu,  Lu Cai, 
  • First Published: 16 January 2017
Research Article
Open Access

ROS-Dependent Activation of Autophagy through the PI3K/Akt/mTOR Pathway Is Induced by Hydroxysafflor Yellow A-Sonodynamic Therapy in THP-1 Macrophages

Yueqing Jiang,  Jiayuan Kou,  Xiaobo Han,  Xuesong Li,  Zhaoyu Zhong,  Zhongni Liu,  Yinghong Zheng,  Ye Tian,  Liming Yang, 
  • First Published: 16 January 2017
Research Article
Open Access

Pathway-Driven Approaches of Interaction between Oxidative Balance and Genetic Polymorphism on Metabolic Syndrome

Ho-Sun Lee,  Taesung Park, 
  • First Published: 16 January 2017
Research Article
Open Access

The Neuroprotective Effects of Carvacrol on Ethanol-Induced Hippocampal Neurons Impairment via the Antioxidative and Antiapoptotic Pathways

Peng Wang,  Qian Luo,  Hui Qiao,  Hui Ding,  Yonggang Cao,  Juan Yu,  Ruxia Liu,  Qianlong Zhang,  Hui Zhu,  Lihui Qu, 
  • First Published: 16 January 2017
Review Article
Open Access

Macrophage Migration Inhibitory Factor as an Emerging Drug Target to Regulate Antioxidant Response Element System

Hiroshi Yukitake,  Masayuki Takizawa,  Haruhide Kimura, 
  • First Published: 16 January 2017
Review Article
Open Access

Antioxidant, Immunomodulating, and Microbial-Modulating Activities of the Sustainable and Ecofriendly Spirulina

Alberto Finamore,  Maura Palmery,  Sarra Bensehaila,  Ilaria Peluso, 
  • First Published: 15 January 2017
Research Article
Open Access

Phytoconstituents and Nutritional Properties of the Fruits of Eleutherococcus divaricatus and Eleutherococcus sessiliflorus: A Study of Non-European Species Cultivated in Poland

Daniel Załuski,  Marta Olech,  Robert Verpoorte,  Inamullah Khan,  Rafał Kuźniewski,  Renata Nowak, 
  • First Published: 15 January 2017
Review Article
Open Access

Exercise Training Attenuates the Dysregulated Expression of Adipokines and Oxidative Stress in White Adipose Tissue

Takuya Sakurai,  Junetsu Ogasawara,  Ken Shirato,  Tetsuya Izawa,  Shuji Oh-ishi,  Yoshinaga Ishibashi,  Zsolt Radák,  Hideki Ohno,  Takako Kizaki, 
  • First Published: 12 January 2017
Research Article
Open Access

Rutin as a Mediator of Lipid Metabolism and Cellular Signaling Pathways Interactions in Fibroblasts Altered by UVA and UVB Radiation

Agnieszka Gęgotek,  Paula Rybałtowska-Kawałko,  Elżbieta Skrzydlewska, 
  • First Published: 12 January 2017
Review Article
Open Access

Nutrition and AGE-ing: Focusing on Alzheimer’s Disease

Giulia Abate,  Mariagrazia Marziano,  Wiramon Rungratanawanich,  Maurizio Memo,  Daniela Uberti, 
  • First Published: 12 January 2017
Review Article
Open Access

Protective Effect of Antioxidants on Neuronal Dysfunction and Plasticity in Huntington’s Disease

Thirunavukkarasu Velusamy,  Archana S. Panneerselvam,  Meera Purushottam,  Muthuswamy Anusuyadevi,  Pramod Kumar Pal,  Sanjeev Jain,  Musthafa Mohamed Essa,  Gilles J. Guillemin,  Mahesh Kandasamy, 
  • First Published: 12 January 2017
Research Article
Open Access

Antioxidants of Phyllanthus emblica L. Bark Extract Provide Hepatoprotection against Ethanol-Induced Hepatic Damage: A Comparison with Silymarin

Renuka Chaphalkar,  Kishori G. Apte,  Yogesh Talekar,  Shreesh Kumar Ojha,  Mukesh Nandave, 
  • First Published: 12 January 2017
Research Article
Open Access

Basic Fibroblast Growth Factor Inhibits Apoptosis and Promotes Proliferation of Adipose-Derived Mesenchymal Stromal Cells Isolated from Patients with Type 2 Diabetes by Reducing Cellular Oxidative Stress

Daria Nawrocka,  Katarzyna Kornicka,  Joanna Szydlarska,  Krzysztof Marycz, 
  • First Published: 11 January 2017

Research Article
Open Access

Semipurified Ethyl Acetate Partition of Methanolic Extract of Melastoma malabathricum Leaves Exerts Gastroprotective Activity Partly via Its Antioxidant-Antisecretory-Anti-Inflammatory Action and Synergistic Action of Several Flavonoid-Based Compounds

Noor Wahida Ismail Suhaimy,  Ahmad Khusairi Noor Azmi,  Norhafizah Mohtarrudin,  Maizatul Hasyima Omar,  Siti Farah Md. Tohid,  Manraj Singh Cheema,  Lay Kek Teh,  Mohd. Zaki Salleh,  Zainul Amiruddin Zakaria, 
  • First Published: 11 January 2017
Research Article
Open Access

Apolipoprotein CIII Overexpression-Induced Hypertriglyceridemia Increases Nonalcoholic Fatty Liver Disease in Association with Inflammation and Cell Death

Adriene A. Paiva,  Helena F. Raposo,  Amarylis C. B. A. Wanschel,  Tarlliza R. Nardelli,  Helena C. F. Oliveira, 
  • First Published: 10 January 2017
Review Article
Open Access

The Role of CYP2E1 in the Drug Metabolism or Bioactivation in the Brain

W. A. García-Suástegui,  L. A. Ramos-Chávez,  M. Rubio-Osornio,  M. Calvillo-Velasco,  J. A. Atzin-Méndez,  J. Guevara,  D. Silva-Adaya, 
  • First Published: 10 January 2017
Research Article
Open Access

Arsenite Effects on Mitochondrial Bioenergetics in Human and Mouse Primary Hepatocytes Follow a Nonlinear Dose Response

Hemantkumar Chavan,  Pamela Christudoss,  Kristen Mickey,  Robert Tessman,  Hong-min Ni,  Russell Swerdlow,  Partha Krishnamurthy, 
  • First Published: 09 January 2017
Review Article
Open Access

Nutritional and Lifestyle Interventions for Age-Related Macular Degeneration: A Review

Ângela Carneiro,  José Paulo Andrade, 
  • First Published: 05 January 2017

Research Article
Open Access

Activation of the Nrf2-Keap 1 Pathway in Short-Term Iodide Excess in Thyroid in Rats

Tingting Wang,  Xue Liang,  Iruni Roshanie Abeysekera,  Umar Iqbal,  Qi Duan,  Gargi Naha,  Laixiang Lin,  Xiaomei Yao, 
  • First Published: 04 January 2017
Research Article
Open Access

EGCG Prevents High Fat Diet-Induced Changes in Gut Microbiota, Decreases of DNA Strand Breaks, and Changes in Expression and DNA Methylation of Dnmt1 and MLH1 in C57BL/6J Male Mice

Marlene Remely,  Franziska Ferk,  Sonja Sterneder,  Tahereh Setayesh,  Sylvia Roth,  Tatjana Kepcija,  Rahil Noorizadeh,  Irene Rebhan,  Martina Greunz,  Johanna Beckmann,  Karl-Heinz Wagner,  Siegfried Knasmüller,  Alexander G. Haslberger, 
  • First Published: 04 January 2017
Research Article
Open Access

Oxidative Stress as a Physiological Pain Response in Full-Term Newborns

S. Perrone,  C. V. Bellieni,  S. Negro,  M. Longini,  A. Santacroce,  M. L. Tataranno,  F. Bazzini,  E. Belvisi,  A. Picardi,  F. Proietti,  L. Iantorno,  G. Buonocore, 
  • First Published: 04 January 2017
Research Article
Open Access

Tualang Honey Protects the Rat Midbrain and Lung against Repeated Paraquat Exposure

Suk Peng Tang,  Sirajudeen Kuttulebbai Nainamohamed Salam,  Hasnan Jaafar,  Siew Hua Gan,  Mustapha Muzaimi,  Siti Amrah Sulaiman, 
  • First Published: 03 January 2017
Research Article
Open Access

MitoTEMPO Prevents Oxalate Induced Injury in NRK-52E Cells via Inhibiting Mitochondrial Dysfunction and Modulating Oxidative Stress

Jiaqiao Zhang,  Qing Wang,  Chuou Xu,  Yuchao Lu,  Henglong Hu,  Baolong Qin,  Yufeng Wang,  Deng He,  Cong Li,  Xiao Yu,  Shaogang Wang,  Jihong Liu, 
  • First Published: 02 January 2017
Research Article
Open Access

Dimethyl Fumarate Induces Glutathione Recycling by Upregulation of Glutathione Reductase

Christina Hoffmann,  Michael Dietrich,  Ann-Kathrin Herrmann,  Teresa Schacht,  Philipp Albrecht,  Axel Methner, 
  • First Published: 01 January 2017