Carbonate can reduce Candida albicans filamentation and biofilm formation in certain media, and it enhances sensitivity to some antifungal drugs.

Bacillus xiamenensis interacts with Moraxella osloensis, and the indole-3-carboxaldehyde produced by B. xiamenensis is a promising agent with specific bactericidal activity against M. osloensis. structure–activity relationship analysis indicates that the indole ring and aldehyde moiety of indole-3-carboxaldehyde are vital for its anti-M. osloensis activity.

By extracting DNA from sound and decayed wood samples at various stages of natural decomposition in both conifer (gymnosperm) and angiosperm wood substrates, we found that DNA quality significantly impacted the ability to amplify and sequence the samples. Despite variability in extraction efficiency, extraction bias (the types of microbes identified) among the methods tested was negligible, lending confidence to comparisons of previously published amplicon data sets. This study provides a cost-benefit table for making protocol decisions and offers novel guidance on fungal DNA extractions from complex organic substrates, which will benefit future metagenomic efforts currently challenging for fungi.

Immobilized freshwater microalgae, specifically a combination of Chlamydomonas reinhardtii and Scenedesmus obliquus, exhibit superior efficiency in the removal of diclofenac from water compared to their free-floating counterparts. This research validates the concept of employing immobilized algal cocktails to effectively degrade diclofenac in wastewater treatment processes. “Created with BioRender.com”.

This study evaluated the effectiveness of prophylactic phage treatment in reducing Salmonella Enteritidis levels in chickens and its impact on their overall gut microbiome. Additionally, we examined the persistence of phages in vivo, both in the presence and absence of Salmonella, and investigated the emergence of bacterial resistance to the 6-phage cocktail used.

The eight TolC-dependent multidrug efflux pumps of Escherichia coli confer resistance to antibiotics. We report that while individual TolC-dependent pumps are dispensable for growth under many stress conditions in the absence of antimicrobials, possibly due to their partially overlapping substrate profiles, TolC-dependent efflux is required for maximal growth under most conditions.

This study investigated the antimicrobial activity of 2,3-N,N-diphenyl quinoxaline derivatives against representative bacteria and mycobacteria species. The findings indicated selective activity against Gram-positive clinical isolates, including Staphylococcus aureus, Enterococcus faecium, and Enterococcus faecalis, particularly antibiotic-resistant isolates. Additionally, two derivatives showed efficacy against bacterial biofilms.

This study developed qPCR probes that specifically distinguish Pseudomonas sivasensis CF10PS3 from other strains within the species. These probes enabled precise monitoring of CF10PS3 persistence in the wheat phyllosphere under field conditions, providing insights into microbial population dynamics.

This study examines the prevalence of tick-borne pathogens in Ixodes ricinus ticks in the north-eastern Italian Alps. It found an average infection rate of 27.1%, with 11 zoonotic pathogens identified, showing varying infection rates across different years and habitats. Notably, co-infections were present in 8% of positive ticks, highlighting the dynamic risk of tick-borne diseases in this region.

The quorum sensing (QS) system of Cereibacter sphaeroides includes six LuxR homologs and one acylhomoserine lactone synthase homolog. Two LuxR homologs, CerM and CerN, are involved in regulating the expression of ctrA, which is part of the CckA/ChpT/CtrA two-component system that controls flagellar motility. This study indicates that CerN-AHL counteracts CerM's repression of ctrA, thereby connecting the QS system with the regulation by the two-component system.