• Issue

    Cancer Medicine: Volume 14, Issue 12

    June 2025

ISSUE INFORMATION

Open Access

Issue Information

  • First Published: 18 June 2025

RESEARCH ARTICLE

Open Access

Place of Death of People With Cancer in 12 Latin American Countries: A Population Study Using National Death Registers

  • First Published: 18 June 2025
Place of Death of People With Cancer in 12 Latin American Countries: A Population Study Using National Death Registers

This study provides a comprehensive analysis of cancer-related place of death (PoD) in 12 Latin American countries, highlighting significant cross-country variations and identifying key factors associated with dying at home versus in a hospital.

Open Access

ER Stress Induced by Artemisinin and Its Derivatives Determines the Susceptibility to Their Synergistic Apoptotic Killing With TRAIL

  • First Published: 23 June 2025
ER Stress Induced by Artemisinin and Its Derivatives Determines the Susceptibility to Their Synergistic Apoptotic Killing With TRAIL

Endoplasmic reticulum stress response is a deterministic factor defining the death in cancer cells treated with a combination of artemisinins and TRAIL.

REVIEW

Open Access

The Impact and Safety of GLP-1 Agents and Breast Cancer

  • First Published: 24 June 2025
The Impact and Safety of GLP-1 Agents and Breast Cancer

Weight gain is a common side effect of breast cancer treatment and is associated with increased cancer progression and mortality. GLP-1 receptor agonists are emerging as potential weight loss therapies for patients with breast cancer. There are key questions central to this paper: Are GLP-1 agents safe? Do they promote weight loss, and do they improve breast cancer outcomes?.

RESEARCH ARTICLE

Open Access

MicroRNA Let-7b-5p Targets IGF1R to Inhibit the Progression of Hepatocellular Carcinoma Through the AKT/mTOR Pathway

  • First Published: 18 June 2025
MicroRNA Let-7b-5p Targets IGF1R to Inhibit the Progression of Hepatocellular Carcinoma Through the AKT/mTOR Pathway

Our study highlights the innovative discovery that miRNAlet-7b-5p targets the IGF1R and inhibits the AKT/mTOR pathway, which has significant implications in the development of novel therapies to combat HCC, including qRT-PCR, clone formation assays, EdU experiments, scratch healing experiments, Transwell experiments, PI experiments, and protein immunoblotting.