Magnetic resonance imaging (MRI) plays an important role in the diagnosis of NMOSD based on the 2015 consensus criteria and its differentiation from other mimickers. High frequency of abnormal Spine and Brain MRI findings was found in Egyptian population. Even though no specific patterns were typical for AQP4-seropositive patients, certain findings may suggest NMOSD diagnosis and warrant AQP4-IgGs testing.

Demyelinating neuropathy was found more often in patients with RA neuropathy than expected. Particular nerve conduction studies parameters are useful for the differential diagnosis of RA patients with neuropathy.