CANO may be a simpler and more convenient indicator for assisting the diagnosis of small airway dysfunction in stable asthma.

This paper proposes a new model based on CNN and CapsNet, which uses CLAHE algorithm to enhance image contrast, input the preprocessed image into the network for training, and use ReLU as the activation function to adjust the parameters to make it optimal. This method combines the advantages of traditional convolutional neural network and capsule network and has a good classification effect on small COVID-19 X-ray image datasets.

FR+CTC is an effective and reliable biomarker for the diagnosis of lung cancer. Combining conventional serum tumor biomarkers, including CA125, CEA, CYFRA21-1, CA153, and NSE, could improve diagnostic efficiency. Furthermore, FR+CTC level is correlated with tumor staging, degree of invasion, pathological subtypes, and tumor size.

In this retrospective study, all the atypical pathogens including Chlamydia psittaci, Legionella and Mycoplasma were identified by mNGS. A comparison of clinical characteristics of nine Chlamydia psittaci pneumonia (C. p), four Legionella pneumonia (L. p) and five Mycoplasma pneumonia (M. p) were firstly accessed.

Can radiomic and clinical characteristics method improve the prediction of treatment response in COVID-19 patients? This study found that small area emphasis and serum creatinine levels have significance in different treatment response groups. It is suggested that the combined model can improve the prognostic prediction and dynamic clinical process analysis finding more potential valuable indicators.

The present study found that expression of forkhead box protein j1 (Foxj1) declined in the airway epithelium of patients with non-CF BE and was related to cilia length and disease severity. It indicated that downregulation of Foxj1 might play an important role in pathogenesis and development of non-CF BE by modulating airway cilia function.

From 309 hospitalized patients with COVID-19, 37.8% had delirium. Regarding the high frequency of important complication, further attention should be paid to the mental state of patients with COVID-19.

Patients with high preoperative CA19-9 values had shorter overall and disease-free survival times. This shows that the preoperative CA19-9 value is a prognostic factor at least as important as CEA in lung metastasis of colorectal carcinoma.

Given the recent change challenge in the treatment of the costs of Pseudomonas infection, the need to understand the risk of recurrence and mortality is important. This study demonstrated, despite of intrinsic limitations of the study design, that monotherapy in a short time (<14 days) is effective, and it is possible to report the susceptibility profile of this pathogen.

D(A-a)O₂ is a valuable indicator for the management of sepsis patient. When D(A-a)O₂ was less than or equal to 300 mmHg, it has no any association with the prognosis of patient, but the mortality rate increases once D(A-a)O₂ became greater than 300 mmHg. The safe range of D(A-a)O₂ for patients with sepsis in the hospital and ICU is less than 300 mmHg.

In this study, we constructed a nomogram to predict the probability of brain metastasis in SCLC patients. We eventually identified 10 factors, including gender, T stage, N stage, ECOG, HGB, LYMPH, PLT, RBP, CEA and NSE, which are readily available in clinical practice.

Cytomegalovirus (CMV) seropositivity has been recently linked to severity and progression of obstructive lung diseases. Among 403 participants from the longitudinal, population-based TESAOD study aged 28–55 years at enrollment, we found that, after full adjustment for covariates, high CMV serology at enrollment was associated with accelerated decline of FEV₁ and FEV₁/FVC (see figure) during follow-up.

Ivacaftor's effectiveness and safety was evaluated in the real world, over 5 years, in patients with at least one G551D mutation within the West of Scotland. Findings include the following: Improvement in mean per cent predicted forced expiratory volume in 1 s (FEV₁), sustained increase in body mass index, decreased intravenous antibiotic use from baseline, reduced hospital bed occupancy from baseline, and good safety profile.

A post-hoc analysis of a steroid stewardship program evaluated the effect of this intervention on glycemic control in AECOPD patients. Steroid stewardship decreased the proportion of glucose readings >180 mg/dL in hospitalized patients. Mean glucose readings were lower but did not reach statistical significance.